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Characterisation And Design Of Tissue Scaffolds

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Characterisation and Design of Tissue Scaffolds

Characterisation and Design of Tissue Scaffolds Book
Author : Paul Tomlins
Publisher : Woodhead Publishing Limited
Release : 2015-10-28
ISBN : 9781782420873
Language : En, Es, Fr & De

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Book Description :

Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues. Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers. Summarizes concepts and current practice in the characterization and design of tissue scaffolds Discusses design and preparation of scaffolds Details how to prepare tissue scaffolds, discusses techniques in characterization, and presents practical considerations for manufacturers

Characterisation and Design of Tissue Scaffolds

Characterisation and Design of Tissue Scaffolds Book
Author : Paul Tomlins
Publisher : Elsevier
Release : 2015-10-30
ISBN : 1782420959
Language : En, Es, Fr & De

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Book Description :

Characterisation and Design of Tissue Scaffolds offers scientists a useful guide on the characterization of tissue scaffolds, detailing what needs to be measured and why, how such measurements can be made, and addressing industrially important issues. Part one provides readers with information on the fundamental considerations in the characterization of tissue scaffolds, while other sections detail how to prepare tissue scaffolds, discuss techniques in characterization, and present practical considerations for manufacturers. Summarizes concepts and current practice in the characterization and design of tissue scaffolds Discusses design and preparation of scaffolds Details how to prepare tissue scaffolds, discusses techniques in characterization, and presents practical considerations for manufacturers

3D Printing for Tissue Engineering and Regenerative Medicine

3D Printing for Tissue Engineering and Regenerative Medicine Book
Author : Murat Guvendiren ,Vahid Serpooshan
Publisher : MDPI
Release : 2020-12-02
ISBN : 3039361120
Language : En, Es, Fr & De

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Book Description :

Three-dimensional (3D) printing enables the fabrication of tissue-engineered constructs and devices from a patient’s own medical data, leading to the creation of anatomically matched and patient-specific constructs. There is a growing interest in applying 3D printing technologies in the fields of tissue engineering and regenerative medicine. The main printing methods include extrusion-based, vat photopolymerization, droplet-based, and powder-based printing. A variety of materials have been used for printing, from metal alloys and ceramics to polymers and elastomers as well as from hydrogels to extracellular matrix proteins. More recently, bioprinting, a subcategory of 3D printing, has enabled the precise assembly of cell-laden biomaterials (i.e., bioinks) for the construction of complex 3D functional living tissues or artificial organs. In this Special Issue, we aim to capture state-of-the-art research papers and the most current review papers focusing on 3D printing for tissue engineering and regenerative medicine. In particular, we seek novel studies on the development of 3D printing and bioprinting approaches, developing printable materials (inks and bioinks), and utilizing 3D-printed scaffolds for tissue engineering and regenerative medicine applications. These applications are not limited to but include scaffolds for in vivo tissue regeneration and tissue analogues for in vitro disease modeling and/or drug screening.

Alginates

Alginates Book
Author : Md Saquib Hasnain,Amit Kumar Nayak
Publisher : CRC Press
Release : 2019-04-01
ISBN : 042965992X
Language : En, Es, Fr & De

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Book Description :

This new volume explores the latest research on the use of alginate as a biopolymer in various biomedical applications and therapeutics. The uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of drugs, nucleic acid materials, proteins and peptides, genes, herbal therapeutic agents, nutraceuticals, and more. This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as hydrogels, gels, composites, nanoparticles, scaffolds, etc., used for the biomedical applications and therapeutics. Alginate, a biopolymer of natural origin, is of immense interest for its variety of applications in pharmaceuticals (as medical diagnostic aids) and in materials science. It is the one of the most abundant natural biopolymers and is considered an excellent excipient because of its non-toxic, stable, and biodegradable properties. Several research innovations have been made on applications of alginate in drug delivery and biomedicines. There needs to be a thorough understanding of the synthesis, purification, and characterization of alginates and its derivatives for their utility in healthcare fields, and this volume offers an abundance of information toward that end.

Nanocomposites for Musculoskeletal Tissue Regeneration

Nanocomposites for Musculoskeletal Tissue Regeneration Book
Author : Huinan Liu
Publisher : Woodhead Publishing
Release : 2016-02-23
ISBN : 178242475X
Language : En, Es, Fr & De

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Book Description :

Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass

Basic Concepts on 3D Cell Culture

Basic Concepts on 3D Cell Culture Book
Author : Cornelia Kasper,Dominik Egger,Antonina Lavrentieva
Publisher : Springer Nature
Release : 2021-06-09
ISBN : 3030667499
Language : En, Es, Fr & De

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Book Description :

This textbook shall introduce the students to 3D cell culture approaches and applications. An overview on existing techniques and equipment is provided and insight into various aspects and challenges that researchers need to consider and face during culture of 3D cells is given. The reader will learn the importance of physiological cell, tissue and organ models and gains important knowledge on 3D analytics. This textbook deepens selected aspects of the textbook “Cell Culture Technology”, which also is published in this series, while offering extended insight into 3D cell culture. The concept of the textbook encompasses various lectures ranging from basics in cell cultivation, tissue engineering, biomaterials and biocompatibility, in vitro test systems and regenerative medicine. The textbook addresses Master- and PhD students interested and/or working in the field of modern cell culture applications and will support the understanding of the essential strategies in 3D cell culture and waken awareness for the potentials and challenges of this application.

Biomaterials for Implants and Scaffolds

Biomaterials for Implants and Scaffolds Book
Author : Qing Li,Yiu-Wing Mai
Publisher : Springer
Release : 2016-11-30
ISBN : 3662535742
Language : En, Es, Fr & De

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Book Description :

This book highlights the latest, cutting-edge advances in implantable biomaterials. It brings together a class of advanced biomaterials in two highly active research areas, namely implants and tissue scaffolds, to underline their respective functional requirements for further development. It is unique in providing a full range of methodological procedures, including materials syntheses, characterisation, cellular tests and mathematical modelling. Covering metallic, ceramic, polymeric and composite materials commonly used in biological applications and clinical therapeutics, it is a valuable resource for anyone wanting to further their understanding of the latest developments in implantable biomaterials. Focusing on biomedical applications in implants and scaffolds, it provides methodological guides to this rapidly growing field. Qing Li and Yiu-Wing Mai are both professors at the University of Sydney, School of Aerospace, Mechanical and Mechatronic Engineering.

Wound Healing Biomaterials Volume 1

Wound Healing Biomaterials   Volume 1 Book
Author : Magnus Ågren
Publisher : Woodhead Publishing
Release : 2016-06-03
ISBN : 0081006055
Language : En, Es, Fr & De

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Book Description :

Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials. Provides more systematic and comprehensive coverage of specific therapies and biomaterials for wound healing Highlights research that is concerned with new therapies, regeneration methods, and the use of biomaterials to assist in wound healing and healing response Presents an organized layout of the material that is carefully arranged with clear titles and comprehensive section headings Looks at tissue regeneration strategies, making this an all encompassing book on the topic of wound care

Science and Principles of Biodegradable and Bioresorbable Medical Polymers

Science and Principles of Biodegradable and Bioresorbable Medical Polymers Book
Author : Xiang Cheng Zhang
Publisher : Woodhead Publishing
Release : 2016-09-22
ISBN : 0081003935
Language : En, Es, Fr & De

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Book Description :

Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers. Provides a practical guide to the fundamentals, synthesis, and processing of bioresorbable polymers in medicine Contains comprehensive coverage of material properties, including unique insights into modeling degradation Written by an eclectic mix of international authors with experience in academia and industry

Characterization of Biomaterials

Characterization of Biomaterials Book
Author : Mangal Roy,Amit Bandyopadhyay,Susmita Bose
Publisher : Elsevier Inc. Chapters
Release : 2013-03-12
ISBN : 0128071036
Language : En, Es, Fr & De

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Book Description :

In joint replacement surgery with suboptimal bone, allograft materials are often used to achieve biological fixation of the metallic implant to the host bone and reducing the implant fixation time. The most commonly used techniques are cemented and hydroxyapatite (HA)-coated metallic implants. Typically, HA coatings are suggested for patients with better bone stock, whereas recommended implant fixation process for most other osteoporotic patients is bone cements. In general, there is a long-standing need to improve the performance of hip and other devices for longer in vivo implant lifetime that can help in reducing the number of revision surgeries, as well as minimizing physical and mental trauma to the patient. To achieve these goals, it is important to understand the mechanical and biological properties of coatings that can influence not only its short- and long-term bioactivity but also life span in vivo. Over the years, it has been recognized that the stability of a coated implant is governed by its physical and mechanical properties. A coating that separates from the implant provides no advantage over an uncoated implant and undesirable due to problems with debris materials, which can lead to osteolysis. Therefore, it is important to properly characterize the coated implants in terms of its physical and mechanical properties. In this chapter, specific details on coating characterization techniques including sample dimensions, sample preparation, experimental procedure and data interpretation are discussed. In particular, the standards and requirements of regulatory organizations are presented elucidating the significance and use of each characterization. It is important to appreciate that mechanical properties of coatings can only be determined with certain coating specification such as coating thickness. This chapter is designed even for non-experts to follow mechanical property characterizations of coatings on medical implants.

Encyclopedia of Biocolloid and Biointerface Science 2 Volume Set

Encyclopedia of Biocolloid and Biointerface Science  2 Volume Set Book
Author : Hiroyuki Ohshima
Publisher : John Wiley & Sons
Release : 2016-09-26
ISBN : 1118542762
Language : En, Es, Fr & De

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Book Description :

This encyclopedia uniquely concentrates on biocolloids and biointerfaces rather than the broader field of colloid and interface science. Biocolloids and biointerfaces are the youngest but increasingly prominent studied area of colloid and interface science, and this encyclopedia uses "soft particles" and "soft interface" as surface models in observing phenomena in biological systems. Provides a detailed description of the fundamental theories, dealing with the physicochemical and theoretical aspects of biocolloid and biointerface science Offers a detailed description of soft interfaces or surfaces Includes detailed description of applications of fundamental biocolloid and biointerface theories to nano-, bio, and environmental sciences A useful and timely resource for researchers and graduates in the field of biocolloid and biointerface science, as well as engineers in the field of nanotechnology, bioscience, and environmental science.

Standardisation in Cell and Tissue Engineering

Standardisation in Cell and Tissue Engineering Book
Author : V Salih
Publisher : Elsevier
Release : 2013-07-31
ISBN : 0857098721
Language : En, Es, Fr & De

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Book Description :

The increased use of biodegradable synthetic or natural scaffolds combined with cells and/or biological molecules, in order to create functional replacement tissue in a damaged tissue site, has led to the need for the development of ‘best practice’ methods in the area of tissue engineering to help ensure the creation of safe, high quality products. Standardisation in cell and tissue engineering introduces concepts and current practice in the field of cell and tissue engineering to a wide audience and aims to provide awareness of the importance of standardisation in this area while suggesting directions for further investigation. Part one provides an overview of methods for cell and tissue engineering and includes chapters on the fundamentals of cell and matrix biology for tissue engineering, 3D collagen biomatrix development, and control and vascularisation of tissue-engineered constructs. Part two begins with a chapter exploring the methods and protocols of standardisation in cell and tissue engineering before moving on to highlight issues of quality control in cell and tissue engineering, standardised chemical analysis and testing of biomaterials and principles of good laboratory practice (GLP) for in vitro cell culture applications. Standardisation in cell and tissue engineering is a standard reference for leading research groups, government agencies, regulatory bodies, and researchers and technicians at all levels across the whole range of disciplines using cell culture within the pharmaceutical, biotechnology and biomedical industries. Introduces concepts and current practice in the field of cell and tissue engineering Highlights the importance of standardisation in cell and tissue engineering and suggests directions for further investigation Explores methods and protocols of standardisation in cell and tissue engineering and issues of quality control in cell and tissue engineering

Cellular Response to Biomaterials

Cellular Response to Biomaterials Book
Author : Lucy Di Silvio
Publisher : Elsevier
Release : 2008-12-22
ISBN : 184569547X
Language : En, Es, Fr & De

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Book Description :

The response of cells to biomaterials is critical in medical devices. Traditionally inert biomaterials were used to minimise the reaction in cells in contact with the material. However, it has been realised that specific cell responses may be beneficial in such areas as encouraging adhesion, healing or cell multiplication. Cellular response to biomaterials discusses the response of cells to a wide range of biomaterials targeted at specific medical applications. Part one discusses cell responses to a variety of polymers and ceramics with chapters on such topics as degradable polymers and biocompatibility. Part two covers cell responses and regenerative medicine with coverage of themes such as vascular grafts, nerve repair and Bioglass®. Part three examines the effect of surfaces and proteins on cell response. Specific chapters review nano-engineered surfaces, the influence of plasma proteins on bone cell adhesion and surface modification of titanium implants. With its distinguished editor and team of international contributors, Cellular response to biomaterials is an essential read for those researching or studying medical devices in industry and academia. Examines the response of cells to a wide range of biomaterials targeted at specific medical applications Discusses cell responses and regenerative medicine with specific chapters on vascular grafts and nerve repair Assesses the effect of surfaces and proteins on cell response including the influence of plasma proteins on cell adhesion and surface modification of titanium implants

Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials

Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials Book
Author : Munmaya Mishra
Publisher : CRC Press
Release : 2017-08-16
ISBN : 135165120X
Language : En, Es, Fr & De

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Book Description :

The Concise Encyclopedia of Biomedical Polymers and Polymeric Biomaterials presents new and selected content from the 11-volume Biomedical Polymers and Polymeric Biomaterials Encyclopedia. The carefully culled content includes groundbreaking work from the earlier published work as well as exclusive online material added since its publication in print. A diverse and global team of renowned scientists provide cutting edge information concerning polymers and polymeric biomaterials. Acknowledging the evolving nature of the field, the encyclopedia also features newly added content in areas such as tissue engineering, tissue repair and reconstruction, and biomimetic materials.

Advances in Polyhydroxyalkanoate PHA Production Volume 2

Advances in Polyhydroxyalkanoate  PHA  Production  Volume 2 Book
Author : Martin Koller
Publisher : MDPI
Release : 2020-05-20
ISBN : 3039286404
Language : En, Es, Fr & De

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Book Description :

Nowadays, we are witnessing highly dynamic research activities related to the intriguing field of biodegradable materials with plastic-like properties. These activities are stimulated by the strengthened public awareness of prevailing ecological issues connected to growing piles of plastic waste and increasing greenhouse gas emissions; this goes hand-in-hand with the ongoing depletion of fossil feedstocks, which are traditionally used to produce full carbon backbone polymers. Polyhydroxyalkanoate (PHA) biopolyesters, a family of plastic-like materials with versatile material properties, are increasing considered to be a future-oriented solution for diminishing these concerns. PHA production is based on renewable resources and occurs in a bio-mediated fashion through the action of living organisms. If accomplished in an optimized way, PHA production and the entire PHA lifecycle are embedded into nature´s closed cycles of carbon. Sustainable and efficient PHA production requires understanding and improvement of all the individual process steps. Holistic improvement of PHA production, applicable on an industrially relevant scale, calls for, inter alia, consolidated knowledge about the enzymatic and genetic particularities of PHA-accumulating organisms, an in-depth understanding of the kinetics of the bioprocess, the selection of appropriate inexpensive fermentation feedstocks, tailoring of PHA composition at the level of its monomeric constituents, optimized biotechnological engineering, and novel strategies for PHA recovery from biomass characterized by low energy and chemical requirements. This Special Issue represents a comprehensive compilation of articles in which these individual aspects have been addressed by globally recognized experts.

Plastic Surgery E Book

Plastic Surgery E Book Book
Author : Geoffrey C Gurtner,Peter C. Neligan
Publisher : Elsevier Health Sciences
Release : 2017-08-08
ISBN : 0323356958
Language : En, Es, Fr & De

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Book Description :

Completely revised to meet the demands of today’s trainee and practicing plastic surgeon, Principles, Volume 1 of Plastic Surgery, 4th Edition, features new full-color clinical photos, dynamic videos, and authoritative coverage of hot topics in the field. Editor-narrated PowerPoint presentations offer a step-by-step audio-visual walkthrough of techniques and procedures in plastic surgery. Offers evidence-based advice from a diverse collection of experts to help you apply the very latest advances in plastic surgery and ensure optimal outcomes. Provides updated coverage of: Digital technology in plastic surgery; Repair and grafting of fat and adipose tissue; Stem cell therapy and tissue engineering; and Treatment of Lymphedema

Manufacturing Characterisation and Properties of Advanced Nanocomposites

Manufacturing  Characterisation and Properties of Advanced Nanocomposites Book
Author : Yu Dong,Alokesh Pramanik,Dongyan Liu,Rehan Umer
Publisher : MDPI
Release : 2018-09-13
ISBN : 303897188X
Language : En, Es, Fr & De

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Book Description :

This book is a printed edition of the Special Issue "Manufacturing, Characterisation and Properties of Advanced Nanocomposites" that was published in J. Compos. Sci.

Marine Algae Extracts

Marine Algae Extracts Book
Author : Se-Kwon Kim,Katarzyna Chojnacka
Publisher : John Wiley & Sons
Release : 2015-01-30
ISBN : 3527679588
Language : En, Es, Fr & De

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Book Description :

Designed as the primary reference for the biotechnological use of macroalgae, this comprehensive handbook covers the entire value chain from the cultivation of algal biomass to harvesting and processing it, to product extraction and formulation. In addition to covering a wide range of product classes, from polysaccharides to terpenes and from enyzmes to biofuels, it systematically discusses current and future applications of algae-derived products in pharmacology, medicine, cosmetics, food and agriculture. In doing so, it brings together the expertise of marine researchers, biotechnologists and process engineers for a one-stop resource on the biotechnology of marine macroalgae.

Tissue Engineering Using Ceramics and Polymers

Tissue Engineering Using Ceramics and Polymers Book
Author : Aldo R. Boccaccini,J Gough
Publisher : Elsevier
Release : 2007-10-31
ISBN : 1845693817
Language : En, Es, Fr & De

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Book Description :

Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering. An innovative and up-to-date reference for professionals and academics Environmental scanning electron microscopy is discussed Analyses bone regeneration and specific types of tisue engineering

A Manual for Biomaterials Scaffold Fabrication Technology

A Manual for Biomaterials Scaffold Fabrication Technology Book
Author : Gilson Khang,Moon Suk Kim,Hai Bang Lee
Publisher : World Scientific Publishing Company
Release : 2007-07-03
ISBN : 9813101601
Language : En, Es, Fr & De

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Book Description :

Tissue engineering has been recognized as offering an alternative technique to whole-organ and tissue transplantation for diseased, failed, or malfunctioned organs. To reconstruct a new tissue via tissue engineering, the following triad components are needed: (1) cells which are harvested and dissociated from the donor tissue; (2) biomaterials as scaffold substrates in which cells are attached and cultured, resulting in implantation at the desired site of the functioning tissue; and (3) growth factors which promote and/or prevent cell adhesion, proliferation, migration, and differentiation. Of these three key components, scaffolds play a critical role in tissue engineering. This timely book focuses on the preparation and characterization of scaffold biomaterials for the application of tissue-engineered scaffolds. More importantly, it serves as an experimental guidebook on the standardization of the fabrication process and characterization of scaffolding technology.