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Cell And Tissue Based Molecular Pathology

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Cell and Tissue Based Molecular Pathology E Book

Cell and Tissue Based Molecular Pathology E Book Book
Author : Raymond R. Tubbs,Mark H. Stoler
Publisher : Elsevier Health Sciences
Release : 2008-09-22
ISBN : 1437719481
Language : En, Es, Fr & De

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Book Description :

This volume in the Foundations in Diagnostic Pathology Series packs today's most essential cell and tissue base molecular pathology into a compact, high-yield format! It focuses on the state of the art in practical validated molecular diagnostics as applied across the fields of surgical pathology and cytology. With an emphasis on current, clinically valid, and diagnostically important applications today and in the near future, you can be assured you’re getting the most up-to-date, authoritative coverage available. Its pragmatic, well-organized approach, nearly 250 full-color illustrations, and at-a-glance boxes and tables make the information you need easy to access. Practical and affordable, this resource is ideal for study and review as well as everyday clinical practice! Offers detailed discussions on today’s technologies to help you select the best test for case evaluation. Presents recognized molecular pathologists who convey the most current information, keeping you on the cusp of your field. Features nearly 250 full-color illustrations that present important pathologic features, enabling you to form a differential diagnosis and compare your findings with actual cases. Uses a consistent, user-friendly format, including at-a-glance boxes and tables for easy reference.

Cell and Tissue Based Molecular Pathology A Volume in the Series Foundations in Diagnostic Pathology

Cell and Tissue Based Molecular Pathology  A Volume in the Series Foundations in Diagnostic Pathology Book
Author : Alexander J. F. Lazar
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Cell and Tissue Based Molecular Pathology A Volume in the Series Foundations in Diagnostic Pathology book written by Alexander J. F. Lazar, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Diagnostic Molecular Pathology Cell and tissue genotyping

Diagnostic Molecular Pathology  Cell and tissue genotyping Book
Author : C. S. Herrington,James O'Donnell McGee
Publisher : Unknown
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Diagnostic Molecular Pathology Cell and tissue genotyping book written by C. S. Herrington,James O'Donnell McGee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Essential Concepts in Molecular Pathology

Essential Concepts in Molecular Pathology Book
Author : William B Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Release : 2019-12-15
ISBN : 9780128132579
Language : En, Es, Fr & De

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Book Description :

Essential Concepts in Molecular Pathology, Second Edition offers and introduction to molecular genetics and the "molecular" aspects of human disease. Illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology and genetics residents, molecular pathology fellows an advanced understanding of molecular mechanisms of disease beyond what they learned in medical and graduate school. All audiences will benefit from learning to think of human disease in terms of complex biological processes rather than focusing on isolated organ systems. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ; this fully updated introductory reference provides the background necessary for the understanding of today's advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Orients the non- pathologists about what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology; the cell biology behind pathophysiology

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology Book
Author : C. S. Herrington,James O'Donnell McGee
Publisher : Unknown
Release : 1992
ISBN : 9780199632411
Language : En, Es, Fr & De

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Book Description :

Download Diagnostic Molecular Pathology book written by C. S. Herrington,James O'Donnell McGee, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Diagnostic Molecular Pathology

Diagnostic Molecular Pathology Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Release : 2016-10-05
ISBN : 0128011572
Language : En, Es, Fr & De

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Book Description :

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions Highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Basic Concepts of Molecular Pathology

Basic Concepts of Molecular Pathology Book
Author : Philip T. Cagle,Timothy Craig Allen
Publisher : Springer Science & Business Media
Release : 2009-06-10
ISBN : 9780387896267
Language : En, Es, Fr & De

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Book Description :

Over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. Molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. As a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. The Molecular Pathology Library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. Basic Concepts of Molecular Pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. Those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the Basic Concepts of Molecular Pathology to be a succinct, portable, user-friendly aid in their practice and studies. The service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.

Molecular Pathology of Liver Diseases

Molecular Pathology of Liver Diseases Book
Author : Satdarshan P. S. Monga
Publisher : Springer Science & Business Media
Release : 2010-12-14
ISBN : 9781441971074
Language : En, Es, Fr & De

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Book Description :

Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Molecular Pathology

Molecular Pathology Book
Author : John M. S. Bartlett,Abeer Shaaban,Fernando Schmitt
Publisher : Cambridge University Press
Release : 2016-03-01
ISBN : 1107443466
Language : En, Es, Fr & De

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Book Description :

Practical overview of current molecular techniques and their applications in each organ system, for practising and trainee pathologists.

Molecular Pathology

Molecular Pathology Book
Author : Antoni Horst
Publisher : CRC Press
Release : 2018-05-04
ISBN : 1351083228
Language : En, Es, Fr & De

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Book Description :

This book provides modern views of developments in medical sciences based on advances in molecular pathology. Topics discussed include the molecule; the genome of eukaryotes and its function; gene regulation; the proteins; molecular aspects of inflammation, immunology, and carcinogenesis; molecular biology of the nervous system; molecular defects in the endocrine system; molecular diseases of the blood and blood-forming tissues; and diagnosis of molecular diseases. Four tables and 75 figures illustrate the concepts and provide a quick means to reference important data. Immunologists, pathologists, geneticists, and all other researchers in the biological and medical sciences will find a wealth of information in this ground-breaking new book.

Molecular Surgical Pathology

Molecular Surgical Pathology Book
Author : Liang Cheng,John N. Eble
Publisher : Springer Science & Business Media
Release : 2012-11-15
ISBN : 1461449006
Language : En, Es, Fr & De

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Book Description :

Molecular Surgical Pathology provides a concise review of recent advancement of molecular pathology in each organ system. The text is intended as a “first knowledge base” in the rapidly evolving field of molecular pathology and is organized in a user friendly outline format. Each chapter is organ-based and covers important aspects of molecular pathology and its impact on our daily practice of surgical pathology. The topics presented herein constitute the fundamentals and core base of knowledge required for the daily practice of surgical pathology. This book focuses on the practical utilities of molecular techniques and molecular biomarkers in daily practice of surgical pathology. The emphasis is on the impact of molecular pathology for tumor classification, diagnosis and differential diagnosis as well as its implications for patient management and personalized care. Numerous tables, diagrams and color illustrations are included throughout. Molecular Surgical Pathology will prove a very useful resource for pathologists in training who are preparing for the Board and in-service examination. It will also be a unique and invaluable resource for medical oncologists, physicians, other medical professionals and basic research scientists with interest in molecular pathology of human cancers.

Rosai and Ackerman s Surgical Pathology E Book

Rosai and Ackerman s Surgical Pathology E Book Book
Author : Juan Rosai
Publisher : Elsevier Health Sciences
Release : 2011-06-20
ISBN : 032308804X
Language : En, Es, Fr & De

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Book Description :

Rosai and Ackerman’s Surgical Pathology delivers the authoritative guidance you need to overcome virtually any challenge in surgical pathology. Recognized globally for his unmatched expertise, preeminent specialist Juan Rosai, MD brings you state-of-the-art coverage of the latest advancements in immunohistochemistry, genetics, molecular biology, prognostic/predictive markers, and much more - equipping you to effectively and efficiently diagnose the complete range of neoplastic and non-neoplastic entities. Efficiently review the clinical presentation, gross and microscopic features, ultrastructural and immunohistochemical findings, differential diagnosis, therapy, and prognosis for virtually every pathologic entity. Compare your findings to more than 3,300 outstanding illustrations that capture the characteristic presentation of every type of lesion. Avoid diagnostic pitfalls using Dr. Rosai's expert observations on what to look for, what to be careful about, and which presentations can be misleading. Find quick answers on tumor staging, quality control procedures, and the handling of gross specimens through valuable appendices. Make optimal use of all the very latest advances including our increased understanding of the genetic basis of inherited and acquired disease, the newest molecular genetic and immunohistochemical techniques, and the most recent WHO disease classification schemes.

Bladder Pathology

Bladder Pathology Book
Author : Liang Cheng,Antonio Lopez-Beltran,David G Bostwick
Publisher : John Wiley & Sons
Release : 2012-05-18
ISBN : 111827539X
Language : En, Es, Fr & De

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Book Description :

The human urinary bladder is subject to a unique andextraordinarily diverse array of congenital, inflammatory,metaplastic, and neoplastic abnormalities. This book providescontemporary, comprehensive, and evidence-based practiceinformation for pathologists, urologists, oncologists, and othermedical professionals. In Bladder Pathology, a full spectrum of pathologicconditions that afflict the bladder and urothelium are describedand lavishly illustrated. With its emphasis on diagnostic criteriaand differential diagnoses, this book is of particular value topracticing pathologists—assisting in the pathologist’srecognition, understanding, and accurate interpretation of thelight microscopic findings in bladder specimens. Features and benefits of this new volume include: • 1,741 high-quality, color illustrations and 112 tables toillustrate the wide range of pathologic and clinical features inthe urinary tract • An evidence-based approach to diagnosis and patientmanagement for infectious, nonneoplastic, and neoplastic conditions • Recent advances in the molecular genetics of the urinarybladder with discussion of their current or potential impact on diagnosis and personalized patient care • With emphasis on the scientific validation of currentdiagnostic methods and their direct application in clinicalpractice, Bladder Pathology is a cutting-edge resource thatnot only offers comprehensive research and clinicalinformation for practicing surgical pathologists, urologists,oncologists, and their clinical colleagues, but also captures agenuine sense of excitement about recent advances in this vital,ever-evolving field.

Bone and Soft Tissue Pathology E Book

Bone and Soft Tissue Pathology E Book Book
Author : Andrew L. Folpe,Carrie Y. Inwards
Publisher : Elsevier Health Sciences
Release : 2009-08-07
ISBN : 1437719473
Language : En, Es, Fr & De

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Book Description :

Bone and Soft Tissue Pathology: A Volume in the Diagnostic Pathology Series, by Andrew L. Folpe, MD and Carrie Y. Inwards, MD, packs today's most essential bone and soft tissue pathology know-how into a compact, high-yield format! The book's pragmatic, well-organized approach—complemented by abundant full-color, high-quality illustrations and at-a-glance tables—makes it easy to access the information you need to quickly and accurately identify pathology specimens. The result is a practical, affordable reference for study and review as well as for everyday clinical practice. Reviews normal histology before examining abnormal findings, enabling you to conveniently compare their characteristics in one place at one time. Covers both neoplastic and non-neoplastic conditions of bone and soft tissue to equip you to meet a wide range of diagnostic challenges. Uses a consistent, user-friendly format to explore each entity's clinical features, pathologic features (gross and microscopic), ancillary studies, differential diagnoses, and prognostic and therapeutic considerations...making it easy to locate specific information on a particular entity. Features abundant boxes and tables throughout that enhance the presentation and accessibility of the material. Offers nearly 1,000 full-color, high-quality illustrations that demonstrate the key features of a wide variety of pathologic lesions to facilitate greater accuracy in identification of specimens.

Bone and Soft Tissue Pathology

Bone and Soft Tissue Pathology Book
Author : Andrew L. Folpe,Carrie Y. Inwards
Publisher : Elsevier Health Sciences
Release : 2010
ISBN : 0443066884
Language : En, Es, Fr & De

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Book Description :

Today's most essential bone and soft tissue pathology know-how in a compact, high-yield format. The book is pragmatic and well-organized, and the Expert Consult provides online access to full text and download-ready illustrations.

Molecular Pathology

Molecular Pathology Book
Author : William B. Coleman,Gregory J. Tsongalis
Publisher : Academic Press
Release : 2017-11-09
ISBN : 0128027878
Language : En, Es, Fr & De

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Book Description :

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Practical Oncologic Molecular Pathology

Practical Oncologic Molecular Pathology Book
Author : Yi Ding,Linsheng Zhang
Publisher : Springer Nature
Release : 2021-07-10
ISBN : 3030732274
Language : En, Es, Fr & De

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Book Description :

This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology. Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals.

Connective Tissue Disease

Connective Tissue Disease Book
Author : Jouni Uitto
Publisher : CRC Press
Release : 2021-07-29
ISBN : 1000447227
Language : En, Es, Fr & De

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Book Description :

This book is a collection of works that canvass many of the recent developments in various areas of connective tissue research. It focuses on the structure of the components, molecular organization and pathology of the extracellular matrix.

Diagnostic Pathology Molecular Oncology E Book

Diagnostic Pathology  Molecular Oncology E Book Book
Author : Mohammad A Vasef,Aaron Auerbach
Publisher : Elsevier Health Sciences
Release : 2019-08-08
ISBN : 0323611451
Language : En, Es, Fr & De

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Book Description :

Covering all aspects of molecular pathology as it relates to the transformation and pathogenesis of cancer, this award-winning volume in the Diagnostic Pathology series is an expert resource for pathologists at all levels of experience and training, both as a quick reference and as an efficient review to improve knowledge and skills. This easily accessible, point-of-care reference features templated, bulleted content that is generously illustrated with charts, graphs, tables, and color photomicrographs of histology with special stains. It offers a practical, clinical approach to examining how molecular mutations affect common medical diseases and identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies. Provides updated information on molecular mutations in different tumors, including solid tumors and hematopoietic neoplasms, and new targeted therapies geared toward these molecular alterations Discusses now widely used immunotherapy treatments, including how immunotherapy has revolutionized the treatment of many neoplasms such as breast and lung carcinomas and lymphoma Features more than 2,000 annotated images throughout, including H&E stains, immunostains, and FISH images Covers timely topics such as: Recent advances in cancer immunotherapy, specifically in the molecular basis of immunotherapy Newly discovered targeted therapies, including multiple lung carcinoma therapies now considered for patients based on existing mutations to specific genes (KRAS, ALK, BRAF, and ROS) The need for integration of myeloid and lymphoid gene panels due to increased knowledge from next generation sequencing studies of new mutations and the resulting newly developed molecular targets Increased usage of next generation sequencing techniques Changes to hematopoietic tumor details based on revised WHO guidelines Recipient of a 2016 BMA Award: Highly Commended, Pathology (previous edition)

Cell Structure Function

Cell Structure   Function Book
Author : Guy Orchard,Brian Nation
Publisher : Oxford University Press
Release : 2015
ISBN : 0199652473
Language : En, Es, Fr & De

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Book Description :

Describes the structural and functional features of the various types of cell from which the human body is formed, focusing on normal cellular structure and function and giving students and trainees a firm grounding in the appearance and behavior of healthy cells and tissues on which can be built a robust understanding of cellular pathology.