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Breathborne Biomarkers And The Human Volatilome

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Breathborne Biomarkers and the Human Volatilome

Breathborne Biomarkers and the Human Volatilome Book
Author : Cristina Davis,Joachim Pleil,Jonathan Beauchamp
Publisher : Elsevier
Release : 2020-06-06
ISBN : 0128223979
Language : En, Es, Fr & De

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Book Description :

Breathborne biomarkers carry information on the state of human health, and their role in aiding clinical diagnosis or in therapeutic monitoring has become increasingly important as advances in the field are made. Breathborne Biomarkers and the Human Volatilome, Second Edition, provides a comprehensive update and reworking of the 2013 book Volatile Biomarkers, by Anton Amann and David Smith. The new editing team has expanded this edition beyond volatile organic compounds to cover the broad field of breath analysis, including the many exciting developments that have occurred since the first edition was published. This thoroughly revised volume includes the latest discoveries and applications in breath research from the world's foremost scientists, and offers insights into related future developments. It is an ideal resource for researchers, scientists, and clinicians with an interest in breath analysis. Presents recent advances in the field of breath analysis Includes an extensive overview of established biomarkers, detection tools, disease targets, specific applications, data analytics, and study design Offers a broad treatise of each topic, from basic concepts to a comprehensive review of discoveries, current consensus of understanding, and prospective future developments Acts as both a primer for beginners and a reference for seasoned researchers

Volatile Biomarkers for Human Health

Volatile Biomarkers for Human Health Book
Author : Hossam Haik
Publisher : Royal Society of Chemistry
Release : 2022-09-30
ISBN : 1839164301
Language : En, Es, Fr & De

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Book Description :

This book offers an outlook into the challenges in the continuing development of volatile biomarkers and their wider availability to healthcare research and industries.

Breath Analysis

Breath Analysis Book
Author : Stefan Weigl
Publisher : Springer Nature
Release : 2022-11-14
ISBN : 3031185269
Language : En, Es, Fr & De

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Book Description :

This volume highlights the potentials as well as the limits and challenges of human breath analysis and describes the current efforts made to advance this promising technology from bench to bed. Human breath analysis is a young, interdisciplinary and innovative research field aiming to provide a smart and non-invasive diagnostic tool, which can be used for screening, detecting and monitoring of diseases or metabolic disorders. This book presents different approaches for breath analysis including real-time and offline mass spectrometry as well as optical and semiconductor gas sensing methods. Besides, the role of smart algorithms to improve the performance of those technologies and the importance of pulmonary function diagnostics for more reliable and meaningful breath analysis are highlighted. Finally, current application scenarios and future perspectives of breath analysis and pulmonary functioning tests are addressed. The volume is useful for researchers, who are new in the field, to easily get an overview of the current status and the challenges present in human breath analysis. Topics from fundamental research over targeted sensor development and application scenarios are described. Thus, this volume covers all development stages providing support and inspiration for engineers, medical doctors and scientists from various fields.

Solving the plasmalogen puzzle from basic science to clinical application

Solving the plasmalogen puzzle     from basic science to clinical application Book
Author : Masanori Honsho,Fabian Dorninger,Johannes Berger
Publisher : Frontiers Media SA
Release : 2023-02-17
ISBN : 2832514944
Language : En, Es, Fr & De

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Book Description :

Download Solving the plasmalogen puzzle from basic science to clinical application book written by Masanori Honsho,Fabian Dorninger,Johannes Berger, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Proceedings of SIE 2022

Proceedings of SIE 2022 Book
Author : Giuseppe Cocorullo,Felice Crupi,Ernesto Limiti
Publisher : Springer Nature
Release : 2023-02-27
ISBN : 303126066X
Language : En, Es, Fr & De

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Book Description :

This book showcases the state of the art in the field of electronics, as presented by researchers and engineers at the 53rd Annual Meeting of the Italian Electronics Society (SIE), held in Rende (CS), Italy, on September 5-7, 2022. It covers a broad range of aspects, including: integrated circuits and systems, micro- and nano-electronic devices, microwave electronics, sensors and microsystems, optoelectronics and photonics, power electronics, electronic systems and applications.

Environmental Management

Environmental Management Book
Author : Marc Lame,Richard Marcantonio
Publisher : Cambridge University Press
Release : 2022-09-22
ISBN : 1009100246
Language : En, Es, Fr & De

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Book Description :

A textbook and manual on environmental management that provides theory and practical skills needed to address current issues and trends.

Karch s Drug Abuse Handbook

Karch s Drug Abuse Handbook Book
Author : Steven Karch,Bruce A. Goldberger
Publisher : CRC Press
Release : 2022-11-25
ISBN : 1351643126
Language : En, Es, Fr & De

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Book Description :

Karch’s Drug Abuse Handbook, Third Edition remains the quintessential compendium addressing the pharmacological, medical, and legal aspects of drugs and informing the forensic community of the latest scientific advances and emergent practices. For this edition, Dr. Karch has brought on clinical and forensic toxicology expert Dr. Bruce Goldberger, editor-in-chief of the Journal of Analytical Toxicology and president of the American Board of Forensic Toxicology, to serve as co-editor. In addition, world-renowned scientists and medical professionals have contributed their work and expertise in tackling the latest developments in drug testing, drug-related medical emergencies, and the drug toxicology. Topics addressed include genetic testing in drug death investigation, pathology, toxicogenetics, alcohol, post-mortem toxicology, new psychoactive substances, the latest legal issues and challenges as well as drugs and drug testing in sports, and the ethical, legal, and practical issues involved. Vivid pictures and diagrams throughout illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. With unparalleled detail, the latest research and the highest level of authoritative medical scientific information, The Drug Abuse Handbook, Third Edition remains the definitive resource for drug related issues.

Advances in the Diagnosis and Control of Johne s Disease

Advances in the Diagnosis and Control of Johne s Disease Book
Author : Marta Alonso-Hearn,Kumi de Silva,Miguel Salgado
Publisher : Frontiers Media SA
Release : 2021-12-01
ISBN : 288971750X
Language : En, Es, Fr & De

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Book Description :

Download Advances in the Diagnosis and Control of Johne s Disease book written by Marta Alonso-Hearn,Kumi de Silva,Miguel Salgado, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomarker Validation

Biomarker Validation Book
Author : Harald Seitz,Sarah Schumacher
Publisher : John Wiley & Sons
Release : 2015-02-23
ISBN : 3527680675
Language : En, Es, Fr & De

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Book Description :

Built on a decade of experience with novel molecular diagnostics, this practice-oriented guide shows how to cope with validation issues during all stages of biomarker development, from the first clinical studies to the eventual commercialization of a new diagnostic test.

Carbon Monoxide in Drug Discovery

Carbon Monoxide in Drug Discovery Book
Author : Leo E. Otterbein,Binghe Wang
Publisher : John Wiley & Sons
Release : 2022-05-10
ISBN : 1119783429
Language : En, Es, Fr & De

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Book Description :

CARBON MONOXIDE IN DRUG DISCOVERY An insightful reference for the latest physiological and therapeutic studies of carbon monoxide In Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential, a team of distinguished authors delivers foundational knowledge, the latest research, and remaining challenges regarding the physiological roles and therapeutic efficacy of carbon monoxide (CO). The editors have included a broad selection of resources from leading experts in the field that discuss the background and physiological roles of CO, a variety of delivery forms including CO prodrugs using benign carriers, CO sensing, therapeutic applications, and clinical trials. Organized by topic to allow each chapter to be read individually, the book covers a wide range of topics, from physiological and patho-physiological mechanisms at the molecular level to clinical applications for multiple disease processes. The editors of Carbon Monoxide in Drug Discovery have created a compelling argument for shifting the accepted understanding of CO from poison to bioactive molecule with enormous clinical benefits. Readers will also benefit from: A thorough introduction to the background and physiological actions of carbon monoxide, including endogenous CO production in sickness and in health Comprehensive explorations of CO delivery forms, including non-carrier formulations, metal-carbonyl complexes, and organic CO donors Practical discussions of carbon monoxide sensing and scavenging, including fluorescent probes for intracellular carbon monoxide detection In-depth examinations of the therapeutic applications of CO, including CO in solid organ transplantation Perfect for professors, graduate students, and postdocs in the fields of biology, pharmacology, immunology, medicinal chemistry, toxicology, and drug delivery, Carbon Monoxide in Drug Discovery: Basics, Pharmacology, and Therapeutic Potential is also an invaluable resource for industrial scientists in these areas.

Volatile Biomarkers

Volatile Biomarkers Book
Author : Anton Amann,David Smith
Publisher : Newnes
Release : 2013-03-27
ISBN : 0444626204
Language : En, Es, Fr & De

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Book Description :

Volatile organic compounds (VOCs) in exhaled breath, sweat or urine carry much information on the state of human health. The role of VOCs in clinical diagnosis and therapeutic monitoring is expected to become increasingly significant due to recent advances in the field. Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine includes the latest discoveries and applications for VOCs from the world's foremost scientists and clinicians working in this emerging analytic area. Appeals to a multidisciplinary audience, including scientists, researchers, and clinicians with an interest in breath analysis Features the latest scientific research and technical breakthroughs in the diagnostic and therapeutic aspects of volatile organic compounds Includes case presentations documenting applications in multiple areas of human health and safety

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications Book
Author : Raquel Cumeras,Xavier Correig
Publisher : CRC Press
Release : 2018-11-09
ISBN : 042978242X
Language : En, Es, Fr & De

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Book Description :

This volume presents a thought-provoking state-of-the-art picture of how volatile compounds are used in metabolomics, currently a hot topic in the metabolomics field. It provides a thorough description of what volatile organic compounds (VOCs) are, why they are important in biomedicine, and what the analytical platforms are used. It also looks at multivariate analysis and databases needs. Because VOCs are end-up compounds of metabolic processes, volatiles can be linked to different diseases or pathologies for both diagnosis and prognosis. The authors provide authoritative information and guidance on the analytical and statistical techniques used and how to identify, and they review the main current areas of application, which include breath metabolomics, cancer diagnosis, and microbial volatiles. Key Features: Presents a thorough overview of volatile research in biomedical applications Examines both gold standard techniques (metabolomics based) and artificial olfactory systems Reviews all aspects of volatile metabolites in biomedicine research, from origin to detection platforms Describes relevant diseases diagnosis and prognosis achievements, including cancer

Exhaled Biomarkers

Exhaled Biomarkers Book
Author : I. Horvath,J.C. de Jongste
Publisher : European Respiratory Society
Release : 2010-09-01
ISBN : 1849840059
Language : En, Es, Fr & De

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Book Description :

Exhaled air contains numerous substances, often in extremely low concentrations. The development of sensitive detection techniques has made it possible to examine the composition of exhaled air in relation to a variety of airway diseases and other disorders. In this book, an overview of current cutting-edge breath analysis techniques and their clinical applications is provided for the clinician. The various contributions give a fascinating perspective of a future where new, highly sensitive methodologies will enable clinicians to diagnose and monitor a wide variety of diseases merely by taking.

Proton Transfer Reaction Mass Spectrometry

Proton Transfer Reaction Mass Spectrometry Book
Author : Andrew M. Ellis,Christopher A. Mayhew
Publisher : John Wiley & Sons
Release : 2014-02-03
ISBN : 9781405176682
Language : En, Es, Fr & De

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Book Description :

Proton Transfer Reaction Mass Spectrometry (PTR-MS) is a rapidly growing analytical technique for detecting and identifying very small quantities of chemical compounds in air. It has seen widespread use in atmospheric monitoring and food science and shows increasing promise in applications such as industrial process monitoring, medical science and in crime and security scenarios. Written by leading researchers, this is the first book devoted to PTR-MS and it provides a comprehensive account of the basic principles, the experimental technique and various applications, thus making this book essential reading for researchers, technicians, postgraduate students and professionals in industry. The book contains nine chapters and is divided into two parts. The first part describes the underlying principles of the PTR-MS technique, including • the relevant ion-molecule chemistry • thermodynamics and reaction kinetics • a discussion of ion sources, drift tubes and mass spectrometers • practical aspects of PTR-MS, including calibration. The second part of the book turns its attention to some of the many applications of PTR-MS, demonstrating the scope and benefits, as well as the limitations, of the technique. The chapters that make up the second part of the book build upon the material presented in the first part and are essentially self-contained reviews focusing on the following topics: • environmental science • food science • medicine • homeland security, and • applications of PTR-MS in liquid analysis.

Flavor Perception

Flavor Perception Book
Author : Andrew J. Taylor,Deborah D. Roberts
Publisher : John Wiley & Sons
Release : 2008-04-15
ISBN : 1405150017
Language : En, Es, Fr & De

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Book Description :

Unlike other human senses, the exact mechanisms that lead to our perception of flavor have not yet been elucidated. It is recognised that the process involves a wide range of stimuli, which are thought likely to interact in a complex way, but, since the chemical compounds and physical structures that activate the flavor sensors change as the food is eaten, measurements of the changes in stimuli with time are essential to an understanding of the relationship between stimuli and perception. It is clear that we need to consider the whole process - the release of flavor chemicals in the mouth, the transport processes to the receptors, the specificity and characteristics of the receptors, the transduction mechanisms and the subsequent processing of signals locally and at higher centres in the brain. This book provides a state-of-the-art review of our current understanding of the key stages of flavor perception for those working in the flavor field, whether in the academic or industrial sector. In particular, it is directed at food scientists and technologists, ingredients suppliers and sensory scientists.

Synthesis of Best Seller Drugs

Synthesis of Best Seller Drugs Book
Author : Ruben Vardanyan,Victor Hruby
Publisher : Academic Press
Release : 2016-01-07
ISBN : 0124115241
Language : En, Es, Fr & De

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Book Description :

Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation

Chemical Ionization Mass Spectrometry

Chemical Ionization Mass Spectrometry Book
Author : Alex. G. Harrison
Publisher : Routledge
Release : 2018-05-11
ISBN : 1351461532
Language : En, Es, Fr & De

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Book Description :

The only comprehensive guide to CIMS applications in structural elucidation and analytical studies Chemical Ionization Mass Spectrometry, 2nd Edition, provides a comprehensive, up-to-date review of CIMS applications in structural elucidation and quantitative analytical studies. For the benefit of readers without a background in gaseous ion chemistry, a thorough review is presented in Chapter 2. Other chapters discuss such topics as reagent ion systems within the context of the thermochemistry and kinetics of the ionization process, including reactions and the type of information obtained; isotopic exchange reactions; stereochemical effects in chemical ionization; and reactive ion/molecule collisions in quadrupole cells. Chemical ionization mass spectra of 13 classes of compounds are discussed in detail to illustrate the influence of different functional groups on the spectra observed. Chemical Ionization Mass Spectrometry, 2nd Edition will be a valuable reference for anyone interested in mass spectrometry and gaseous ion chemistry in general.

Principles of Organic Chemistry

Principles of Organic Chemistry Book
Author : Robert J. Ouellette,J. David Rawn
Publisher : Academic Press
Release : 2015-02-13
ISBN : 0128026340
Language : En, Es, Fr & De

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Book Description :

Class-tested and thoughtfully designed for student engagement, Principles of Organic Chemistry provides the tools and foundations needed by students in a short course or one-semester class on the subject. This book does not dilute the material or rely on rote memorization. Rather, it focuses on the underlying principles in order to make accessible the science that underpins so much of our day-to-day lives, as well as present further study and practice in medical and scientific fields. This book provides context and structure for learning the fundamental principles of organic chemistry, enabling the reader to proceed from simple to complex examples in a systematic and logical way. Utilizing clear and consistently colored figures, Principles of Organic Chemistry begins by exploring the step-by-step processes (or mechanisms) by which reactions occur to create molecular structures. It then describes some of the many ways these reactions make new compounds, examined by functional groups and corresponding common reaction mechanisms. Throughout, this book includes biochemical and pharmaceutical examples with varying degrees of difficulty, with worked answers and without, as well as advanced topics in later chapters for optional coverage. Incorporates valuable and engaging applications of the content to biological and industrial uses Includes a wealth of useful figures and problems to support reader comprehension and study Provides a high quality chapter on stereochemistry as well as advanced topics such as synthetic polymers and spectroscopy for class customization

Modern Sample Preparation for Chromatography

Modern Sample Preparation for Chromatography Book
Author : Serban Moldoveanu,Victor David
Publisher : Elsevier
Release : 2021-02-24
ISBN : 0323898203
Language : En, Es, Fr & De

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Book Description :

Modern Sample Preparation for Chromatography, Second Edition explains the principles of sample preparation for chromatographic analysis. A variety of procedures are applied to make real-world samples amenable for chromatographic analysis and to improve results. This book's authors discuss each procedure’s advantages, disadvantages and their applicability to different types of samples, along with their fit for different types of chromatographic analysis. The book contains numerous literature references and examples of sample preparation for different matrices and new sections on green approaches in sample preparation, progress in automation of sample preparation, non-conventional solvents for LLE (ionic liquids, deep eutectic mixtures, and others), and more. Presents numerous techniques applied for sample preparation for chromatographic analysis Provides an up-to-date source of information regarding the progress made in sample preparation for chromatography Describes examples for specific types of matrices, providing a guide for choosing the appropriate sample preparation method for a given analysis

Synthesis of Essential Drugs

Synthesis of Essential Drugs Book
Author : Ruben Vardanyan,Victor Hruby
Publisher : Elsevier
Release : 2006-03-10
ISBN : 9780080462127
Language : En, Es, Fr & De

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Book Description :

Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for these drugs, this book fills the gap that exists in the literature of drug synthesis. It provides the kind of information that will be of interest to those who work, or plan to begin work, in the areas of biologically active compounds and the synthesis of medicinal drugs. This book presents the synthesis of various groups of drugs in an order similar to that traditionally presented in a pharmacology curriculum. This was done with a very specific goal in mind – to harmonize the chemical aspects with the pharmacology curriculum in a manner useful to chemists. Practically every chapter begins with an accepted brief definition and description of a particular group of drugs, proposes their classification, and briefly explains the present model of their action. This is followed by a detailed discussion of methods for their synthesis. Of the thousands of drugs existing on the pharmaceutical market, the book mainly covers generic drugs that are included in the WHO’s Essential List of Drugs. For practically all of the 700+ drugs described in the book, references (around 2350) to the methods of their synthesis are given along with the most widespread synonyms. Synthesis of Essential Drugs is an excellent handbook for chemists, biochemists, medicinal chemists, pharmacists, pharmacologists, scientists, professionals, students, university libraries, researchers, medical doctors and students, and professionals working in medicinal chemistry. * Provides a brief description of methods of synthesis, activity and implementation of all drug types * Includes synonyms * Includes over 2300 references