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Deep Brain Stimulation

Deep Brain Stimulation Book
Author : Kelvin L. Chou, MD,Susan Grube,Parag G. Patil
Publisher : Demos Medical Publishing
Release : 2011-12-21
ISBN : 1936303116
Language : En, Es, Fr & De

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Book Description :

"A deep brain stimulator (DBS) device is like a pacemaker for the heart, but the electrodes are placed into the brain. DBS helps in neurological disorders by changing the activity of brain cells depending on where the electrodes are placed. In 1973, Yoshio Hosobuchi first performed chronic deep brain stimulation, to treat pain, by implanting electrodes. In 2002, long-term results of pallidal stimulation were reported for Parkinson's disease. Thus, this book discusses how Parkinson's disease, essential tremor, dystonia, and a few other neurological and psychiatric disorders are treated with DBS"--Provided by publisher.

Deep Brain Stimulation for Neurological Disorders

Deep Brain Stimulation for Neurological Disorders Book
Author : Toru Itakura
Publisher : Springer
Release : 2014-08-28
ISBN : 3319084763
Language : En, Es, Fr & De

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Book Description :

Chronic electrical stimulation of the brain has demonstrated excellent outcomes in patients with Parkinson’s disease and has recently also been applied to various other neurological diseases. This comprehensive, up-to-date textbook will meet the needs of all who wish to learn more about the application of deep brain stimulation and will provide a sound basis for safe and accurate surgery. The book comprises two main parts, the first of which presents relevant anatomical and functional background information on the basal ganglia, thalamus and other brain structures as well as on the mechanism of brain stimulation. The second part describes clinical studies on deep brain stimulation, covering results in a range of movement disorders and psychiatric diseases and also important aspects of instrumentation and technique. The authors are outstanding scientists and experts in the field from across the world.

Brain Stimulation in Psychiatry

Brain Stimulation in Psychiatry Book
Author : Charles H. Kellner
Publisher : Cambridge University Press
Release : 2012-05-31
ISBN : 0521172551
Language : En, Es, Fr & De

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Book Description :

An authoritative, concise, how-to guide to the various brain stimulation treatments used in psychiatry.

Transcranial Brain Stimulation

Transcranial Brain Stimulation Book
Author : Carlo Miniussi,Walter Paulus,Paolo M. Rossini
Publisher : CRC Press
Release : 2012-12-03
ISBN : 1439875715
Language : En, Es, Fr & De

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Book Description :

Since the discovery of transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (tES), these non-invasive brain stimulation (NIBS) techniques have been used to investigate the state of cortical excitability, and the excitability of the cortico-cortical and corticospinal pathways. In addition, these techniques have been found to induce neuroplasticity—a significant breakthrough in our understanding of the brain at work. Transcranial Brain Stimulation presents a wide range of possible brain stimulation applications and discusses what new information can be gained from using this technique on the dynamics of brain functions, hierarchical organization, and effective connectivity. Implications of recent findings related to the therapeutic application are discussed by an international group of leading experts, who present practical guidance on the use of each technique, and catalog the results of numerous TMS and tES studies on biological and behavioral effects.

Brain Stimulation Therapies for Clinicians Second Edition

Brain Stimulation Therapies for Clinicians  Second Edition Book
Author : Edmund S. Higgins, M.D.,Mark S. George, M.D.
Publisher : American Psychiatric Pub
Release : 2019-08-13
ISBN : 1615371672
Language : En, Es, Fr & De

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Book Description :

This new edition provides thoroughly updated information on the growing list of electrical stimulation therapies now in use or under study, including electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), transcranial magnetic stimulation (TMS), deep brain stimulation (DBS), cortical stimulation (CS), and transcranial direct current stimulation (TDCS), as well as new coverage of promising treatments such as low intensity focused ultrasound pulsation (LIFUP) and temporal interference stimulation (TI).

Brain Stimulation

Brain Stimulation Book
Author : Filippo Agnesi,Matthew D. Johnson,Jerrold L. Vitek
Publisher : Elsevier Inc. Chapters
Release : 2013-11-11
ISBN : 0128080108
Language : En, Es, Fr & De

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Book Description :

Chronic deep brain stimulation (DBS) has become a widely accepted surgical treatment for medication-refractory movement disorders and is under evaluation for a variety of neurological disorders. In order to create opportunities to improve treatment efficacy, streamline parameter selection, and foster new potential applications, it is important to have a clear and comprehensive understanding of how DBS works. Although early hypothesis proposed that high-frequency electrical stimulation inhibited neuronal activity proximal to the active electrode, recent studies have suggested that the output of the stimulated nuclei is paradoxically activated by DBS. Such regular, time-locked output is thought to override the transmission of pathological bursting and oscillatory activity through the stimulated nuclei, as well as inducing synaptic plasticity and network reorganization. This chapter reviews electrophysiological experiments, biochemical analyses, computer modeling and imaging studies positing that, although general principles exist, the therapeutic mechanism(s) of action depend both on the site of stimulation and on the disorder being treated.

Deep Brain Stimulation Management

Deep Brain Stimulation Management Book
Author : William J. Marks, Jr
Publisher : Cambridge University Press
Release : 2015-08-31
ISBN : 1107084253
Language : En, Es, Fr & De

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Book Description :

Essential reference guide for clinicians working with DBS patients, fully revised throughout with new chapters on epilepsy and psychiatric disorders.

Deep Brain Stimulation Programming

Deep Brain Stimulation Programming Book
Author : Erwin B. Montgomery, Jr.
Publisher : Oxford University Press
Release : 2016-09-22
ISBN : 0190259604
Language : En, Es, Fr & De

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Book Description :

Deep brain stimulation programming (DBS) continues to grow as an effective therapy for a wide range of neurological and psychiatric disorders, helping patients reach optimal control of their disorder. With the technique finding so much success, the next question is how to make the complexities of post-operative programming cost-effective, especially when traditional medications and treatments can no longer do the job. The second edition of Deep Brain Stimulation Programming is fully revised and up-to-date with the latest technologies and focuses on post-operative programing, which no other text does. This book provides programmers with a foundation of the brain as an electrical device, focusing on the mechanisms by which neurons respond to electrical stimulation, how to control the stimulation and the regional anatomy, and the many variations that influence a patient's response to DBS. Dr. Montgomery explores new techniques of programming; including those based on stimulation frequency, closed-loop DBS, and the roles of oscillators in DBS; and new technological advances that make pre-existing theories of pathophysiology obsolete. Key Features of the Second Edition Include . Highlights post-operative deep brain stimulation; . Includes the most recent discoveries in deep brain stimulation programming; . Highly illustrated with figures for absorption of key programming and techniques; . Provides an appendix of additional resources available through the Greenville Neuromodulation Center. "

Intraoperative Neurophysiological Monitoring for Deep Brain Stimulation

Intraoperative Neurophysiological Monitoring for Deep Brain Stimulation Book
Author : Erwin B. Montgomery, Jr.,Erwin B. Montgomery (Jr.)
Publisher : Oxford University Press (UK)
Release : 2014-07-16
ISBN : 0199351007
Language : En, Es, Fr & De

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Book Description :

A thorough understanding of electricity, electronics, biophysics, neurophysiology, and neuroanatomy is important to render more tractable, and otherwise complex, electrophysiologically-based targeting in the brain during operative manipulations. Most importantly, electrophysiological monitoring requires controlling the movement of electrons in electronic circuits in order to prevent irreversible damage. This new textbook presents a fundamental discussion of electrons, the forces moving these electrons, and the electrical circuits controlling these forces. The forces that allow recording and analysis also permeate the environment producing interference, such as noise and artifacts. Intraoperative Neurophysiological Monitoring for Deep Brain Stimulation discusses how to avoid or suppress noise and artifacts for the most successful surgical outcome.

Brain Stimulation

Brain Stimulation Book
Author : David T. Brocker,Warren M. Grill
Publisher : Elsevier Inc. Chapters
Release : 2013-11-11
ISBN : 0128080078
Language : En, Es, Fr & De

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Book Description :

Deep brain stimulation is a remarkable therapy that has mainstreamed electrical stimulation of the brain for the treatment of neurological dysfunction. To appreciate the mechanisms of deep brain stimulation, we need to understand the excitability of neural tissue. Here, we survey the pertinent principles of electrical excitation in the brain. The amount of current delivered and the tissue conductivity together determine the strength and extent of potentials generated by stimulation. The electrode–tissue interface is an important junction where electrical charge carriers in the stimulation hardware are converted to ionic charge carriers in the tissue. Cathodic stimulation tends to depolarize neural elements more easily than anodic stimulation. The current–distance relationship describes how the amount of current needed to excite an axon increases as a function of its distance from the electrode. This relationship also depends on the axon’s diameter because large-diameter axons are excited more easily than small-diameter axons. For a given axon, the strength–duration relationship describes the inverse relationship between threshold current amplitude and pulse duration. Specific stimulation parameters must be considered to avoid stimulation-induced tissue damage. A strong foundation in these principles facilitates understanding of the complex effects of electrical stimulation in the brain.

Brain Stimulation

Brain Stimulation Book
Author : Robert S. Fisher
Publisher : Elsevier Inc. Chapters
Release : 2013-11-11
ISBN : 012808023X
Language : En, Es, Fr & De

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Book Description :

Deep brain stimulation for seizures has been applied to cerebellum, caudate, locus coeruleus, subthalamic nucleus, mammillary bodies, centromedian thalamus, anterior nucleus of thalamus, hippocampus and amygdala, hippocampal commissure, corpus callosum, neocortex, and occasionally to other sites. Animal and clinical studies have primarily investigated seizure prevention and, to a lessersmaller extent, seizure interruption. No studies have yet shown stimulation able to cure epilepsy. A wide variety of stimulation parameters have been employed in multiple different combinations of frequencies, amplitudes, and durations. Literature review identifies at least 52 clinical studies of brain stimulation for epilepsy in 817 patients. Two studies were large, randomized, and controlled, one in the anterior nucleus of thalamus and another at the cortical or hippocampal seizure focus; both of these studies showed efficacy and tolerability of stimulation. Many questions remain. We do not know the mechanisms, the best stimulation parameters, the best patient population, or how to predict benefit in advance. We do not know why benefit of neurostimulation for epilepsy seems to increase over time or whether there are long-term deleterious effects. All of these questions may be answerable with a combination of laboratory research and clinical experience.

Twenty Things to Know about Deep Brain Stimulation

Twenty Things to Know about Deep Brain Stimulation Book
Author : Erwin B. Montgomery, Jr.
Publisher : Oxford University Press, USA
Release : 2015-01-30
ISBN : 0199338825
Language : En, Es, Fr & De

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Book Description :

Twenty Things to Know About Deep Brain Stimulation is an extensive and in-depth critical analysis of the field of Deep Brain Stimulation (DBS) from what many may consider a revolutionary perspective. This book demonstrates the unique nature and incredible promise of DBS and shows how it is unparalleled as a therapeutic intervention. Dr. Montgomery provides an epistemic analysis of the presuppositions, assumptions and fallacies underlying current clinical understanding of DBS as well as the physiology and pathophysiology affected by DBS. Reviews of the safety and efficacy for a number of conditions, patient selections and issues in the post-operative management are also included. Given the revolutionary potential and the complexity of DBS in an ever changing healthcare delivery context, the ethics of DBS are discussed in detail.

Brain Stimulation and Behavioral Change

Brain Stimulation and Behavioral Change Book
Author : Claudio Lucchiari,Nicholas J. Kelley,Maria E. Vanutelli,Roberta Ferrucci
Publisher : Frontiers Media SA
Release : 2019-05-15
ISBN : 2889458385
Language : En, Es, Fr & De

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Book Description :

The eBook entitled “Brain Stimulation and Behavioral Change” is a collection of articles about the use of transcranial electric stimulation (tES) to change behaviors and face pathological conditions, to enhance cognition and to explore cerebral functions using safe and non-invasive brain modulation techniques. The tESs include transcranial direct current stimulation (tDCS), transcranial alternate current stimulation (tACS), and, due to the way it induces changes in the brain, Transcranial Magnetic Stimulation (TMS). The use of tES has recently exploded. Certainly, one reason for this explosion of research is that it is a cheap way to change behavior. However, on the other hand, we still know very little about the neural mechanisms that underlie tES. The present eBook includes both original studies and reviews. It covers a wide scope of arguments, including studies aimed at testing the potential ability of tES in mitigating physical and psychiatric symptoms, and to support neurological rehabilitation, enhancing reading abilities, motor abilities, and creativity. Furthermore, some contributions about the role of tES in discovering and mapping the neuro-functional correlates of higher cognitive functions are also included. The common background of the contributions included in the eBook lies in the idea that we need sound scientific evidence about how to move these techniques from labs to real-life contexts. Addressing these issues and understanding the real potentialities of tES in clinical and non-clinical applications require a significant cross-fertilization between disciplines. We hope this eBook will be able to boost the discussion on this vital topic.

Deep Brain Stimulation

Deep Brain Stimulation Book
Author : Damiaan Denys,Matthijs Feenstra,Rick Schuurman
Publisher : Springer Science & Business Media
Release : 2012-09-14
ISBN : 3642309917
Language : En, Es, Fr & De

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Book Description :

Deep Brain Stimulation: A New Frontier in Psychiatry provides an overview of current developments and the future possibilities of deep brain stimulation for patients with therapy-refractory psychiatric disorders. The side-by-side presentation of clinical applications and animal research provides a truly translational approach. Also included is a special chapter on the ethical issues involved in deep brain stimulation in psychiatry. Deep brain stimulation of selected brain areas has been shown to result in a substantial improvement of symptoms and quality of life in patients suffering from obsessive-compulsive disorder, major depressive disorder and drug addiction. Although it is still an experimental therapy and the number of psychiatric patients that are treated is low, its effectiveness and safety makes deep brain stimulation the most promising therapy for treating other serious and life-threatening psychiatric conditions.

Models and Simulations of the Electric Field in Deep Brain Stimulation

Models and Simulations of the Electric Field in Deep Brain Stimulation Book
Author : Fabiola Alonso
Publisher : Linköping University Electronic Press
Release : 2018-09-10
ISBN : 917685261X
Language : En, Es, Fr & De

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Book Description :

Deep brain stimulation (DBS) is an established surgical therapy for movement disorders such as Parkinson’s disease (PD) and essential tremor (ET). A thin electrode is implanted in a predefined area of the brain with the use of stereotactic neurosurgery. In the last few years new DBS electrodes and systems have been developed with possibilities for using more parameters for control of the stimulation volume. In this thesis, simulations using the finite element method (FEM) have been developed and used for investigation of the electric field (EF) extension around different types of DBS lead designs (symmetric, steering) and stimulation modes (voltage, current). The electrode surrounding was represented either with a homogeneous model or a patient-specific model based on individual preoperative magnetic resonance imaging (MRI). The EF was visualized and compared for different lead designs and operating modes. In Paper I, the EF was quantitatively investigated around two lead designs (3389 and 6148) simulated to operate in voltage and current mode under acute and chronic time points following implantation.Simulations showed a major impact on the EF extension between postoperative time points which may explain the clinical decisions to change the stimulation amplitude weeks after implantation. In Paper II, the simulations were expanded to include two leads having steering function (6180, Surestim1) and patient-specific FEM simulations in the zona incerta. It was found that both the heterogeneity of the tissue and the operating mode, influence the EF distribution and that equivalent contact configurations of the leads result in similar EF. The steering mode presented larger volumes in current mode when using equivalent amplitudes. Simulations comparing DBS and intraoperative stimulation test using a microelectrode recording (MER) system (Paper III), showed that several parallel MER leads and the presence of the non-active DBS contacts influence the EF distribution and that the DBS EF volume can cover, but also extend to, other anatomical areas. Paper IV introduces a method for an objective exploitation of intraoperative stimulation test data in order to identify the optimal implant position in the thalamus of the chronic DBS lead. Patient-specific EF simulations were related to the anatomy with the help of brain atlases and the clinical effects which were quantified by accelerometers. The first results indicate that the good clinical effect in ET is due to several structures around the ventral intermediate nucleus of the thalamus.

Fundamentals and Clinics of Deep Brain Stimulation

Fundamentals and Clinics of Deep Brain Stimulation Book
Author : Yasin Temel,Albert F.G. Leentjens,Rob M.A. de Bie,Stephan Chabardes,Alfonso Fasano
Publisher : Springer Nature
Release : 2020-03-24
ISBN : 3030363465
Language : En, Es, Fr & De

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Book Description :

This book provides a state-of-the-art overview of our current understanding of deep brain stimulation (DBS) for the treatment of neurological and psychiatric disorders. With a broad multidisciplinary scope, it presents contributions from leading experts in the field from Europe and America, who share not only their knowledge, but their experience as well. The book focuses both on basic and theoretical aspects of DBS, as well as clinical and practical aspects. It follows an evidence-based approach, and where possible offers clinical recommendations based on published guidelines. It starts with a general section, which discusses basic principles and general considerations. This is followed a sections dedicated to neurological disorders, and psychiatric disorders, in which only accepted indications are discussed. All experimental indications are discussed in the final chapter. The text is supplemented with numerous illustrations. Intended for medical specialists and residents involved in the treatment of patients with DBS, it also appeals to other professionals working with DBS patients, such as psychologists, nurses, physiotherapists, as well as basic and clinical neuroscientists.

Deep Brain Stimulation Programming

Deep Brain Stimulation Programming Book
Author : Erwin B. Montgomery, Jr., MD
Publisher : Oxford University Press
Release : 2010-04-13
ISBN : 0199890013
Language : En, Es, Fr & De

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Book Description :

Deep Brain Stimulation (DBS) is a remarkable therapy for an expanding range of neurological and psychiatric disorders. In many cases it is better than best medical therapy and succeeds even when brain transplants fail. Yet despite the remarkable benefits, many physicians and healthcare professionals seem hesitant to embrace this therapy. Post-operative programming of the DBS systems seems unfamiliar, even mysterious, and is viewed as difficult and time consuming. However, DBS programming is rational and can be efficient and effective if one understands the basing underlying concepts of electronics, electrophysiology, and the relevant regional anatomy. Even these principles can be relatively easy to grasp. The book helps the reader to obtain an intuitive understanding of the basic principles of electronics, electrophysiology and the relevant regional anatomy through the use of readily understood metaphors and numerous illustrations. In addition a number of tools are provided including algorithms to ensure efficient and thorough programming. Forms are provided to help with documentation. In addition, DBS related research provides a remarkable tool to understand how the brain works and what happens in diseases such as Parkinson's disease. Already long cherished theories of the pathophysiology of Parkinson's disease must be abandoned. Indeed, these DBS derived insights suggest fundamental revisions of theories of brain function are in order. The book provides an introduction to where some of the new theories may lead particularly with the growing awareness of the importance of oscillations in the brain's activities. The brain has more in common with electrical devices, such as computers, than it does to a stew of chemicals. DBS operates at the electrical level in the brain, which is fundamental to how the brain creates, manipulates and conveys information and may indeed be fundamental to the misinformation the results in the dysfunction related to disorders of the brain. For downloadable forms and other relevant material, please visit: http://www.uab.edu/DBS_PrinciplesAndPractice

The Stimulated Brain

The Stimulated Brain Book
Author : Roi Cohen Kadosh
Publisher : Elsevier
Release : 2014-06-01
ISBN : 0124047122
Language : En, Es, Fr & De

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Book Description :

The Stimulated Brain—which garnered an Honorable Mention for Biomedicine & Neuroscience at the 2015 PROSE Awards from the Association of American Publishers—presents the first integration of findings on brain stimulation from different research fields with a primary focus on Transcranial Electrical Stimulation (tES), one of the most frequently used noninvasive stimulation methods. The last decade has witnessed a significant increase in the amount of research exploring how noninvasive brain stimulation can not only modulate but also enhance cognition and brain functions. However, although Transcranial Magnetic Stimulation (TMS) and particularly tES have the potential to become more widely applicable techniques (as they come with none of the risks associated with deep brain stimulation) the reference literature on these neurotechnologies has been sparse. This resource provides a broad survey of current knowledge, and also marks future directions in cognitive and neuro-enhancement. It expands our understanding of basic research findings from animals and humans, including clear translational benefits for applied research and the therapeutic use of noninvasive brain stimulation methods. The book's coverage includes a primer that paves the way to a more advanced knowledge of tES and its physiological basis; current research findings on cognitive and neuro-enhancement in animals and typical and atypical human populations, such as neurological patients; and discussions of future directions, including specific neuroethical issues and pathways for collaboration and entrepreneurialism. The Stimulated Brain is the first book to provide a comprehensive understanding of different aspects of noninvasive brain stimulation that are critical for scientists, clinicians, and those who are interested in “stimulating their minds by exploring this fascinating field of research. Honorable Mention for Biomedicine & Neuroscience in the 2015 PROSE Awards from the Association of American Publishers The only reference on the market to focus on transcranial electrical stimulation (tES) Coverage across technical, historical, and application topics makes this the single, comprehensive resource for researchers and students Edited book with chapters authored by international leaders in the fields of medicine, neuroscience, psychology, and philosophy—providing the broadest, most expert coverage available

Advance Brain Stimulation by Psychoconduction

Advance Brain Stimulation by Psychoconduction Book
Author : Chester Litvin Phd
Publisher : Trafford Publishing
Release : 2012-02
ISBN : 1466901527
Language : En, Es, Fr & De

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Book Description :

This book is a series of exercises to reeducate the brain cells. This explains the method and system for the psychological treatment by brain stimulation of the psychologically disordered object. This provides a possibility to stimulate the simple cells to assist the complex cells in order to correctly perform the assigned command. The system reeducates the brain cells by transferring the same information to various parts of the brain. The psychoconduction is the process of translating the simplified symbol to various parts of the brain. The goal is to correct or replace the complex cells, which can be audio, video, kinesthetic, and/or olfactory. Those cells have difficulty to process information correctly and need to be tune up and balance. The tune up of the different parts of the brain on the same information is providing correction of the brain complex cell. This method provides many patterns of video, audio, kinesthetic symbols. The patterns of visual, audio, kinesthetic, olfactory, tactile, and musical information can be based on the binary arithmetic and can be different from binary base. Those various patterns called Litvin's Code. In this book the patterns are based on binary code.

Deep Brain Stimulation and Epilepsy

Deep Brain Stimulation and Epilepsy Book
Author : Hans O. Lüders
Publisher : CRC Press
Release : 2020-08-27
ISBN : 1000148955
Language : En, Es, Fr & De

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Book Description :

Deep brain stimulation has been used effectively for many years to treat patients suffering from Parkinson's disease. Now, neurologists and neurosurgeons are using electric pulse generators to block abnormal activity, i.e. epileptic fits. Promising research results indicate that electric pulses implanted deep in the brain can affect neurocircuitry and help stop oncoming seizures. Supplying a solid background on brain stimulation and its application to epilepsy, Deep Brain Stimulation and Epilepsy provides a historical overview, explores pathogenesis of brain stimulation, discusses animal experiments and human studies, and explores future prospects of brain stimulation for epileptic control. The editor and his team of contributors distill information drawn directly from the literature into one convenient resource.