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Brain Oscillations Synchrony And Plasticity

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Brain Oscillations Synchrony and Plasticity

Brain Oscillations  Synchrony and Plasticity Book
Author : Jos J. Eggermont
Publisher : Academic Press
Release : 2021-01-11
ISBN : 0128204087
Language : En, Es, Fr & De

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Book Description :

Brain Oscillations, Synchrony and Plasticity: Basic Principles and Application to Auditory-Related Disorders discusses the role of brain oscillations, especially with respect to the auditory system and how those oscillations are measured, change over the lifespan, and falter leading to a variety of psychiatric and neurological disorders. The book begins with a description of these cortical rhythm oscillations and how they function in both the normal and pathological brain. It explains how these oscillations are important to auditory, executive and attention brain networks and how they relate to the development, production and deterioration of speech and language. In addition, treatment of malfunctioning cortical rhythms are reviewed using neuromodulation, such as transcranial magnetic, direct current, random noise, and alternating current stimulation, as well as focused ultrasound. The book concludes by describing the potential role of oscillations in dyslexia, autism, schizophrenia and Alzheimer’s disease. Introduces readers to brain imaging methods such as structural and functional magnetic resonance imaging, EEG and magnetoencephalography, in the study of brain oscillations, synchrony and networks of the normal and pathological brain Highlights the role of brain oscillations in perception and cognition, in particular with respect to the auditory system, speech and language Describes lifespan changes, from preterm to senescence, of brain oscillations, brain networks and how they relate to the development and deterioration of speech and language Explains the effects of hearing loss on neural network change in the auditory and non-auditory networks such as the default mode-, the salience-, the executive- and attention networks Illustrates the breakdown of network connections in auditory-related disorders such as tinnitus and in psychiatric disorders with a strong auditory, speech and language component

Manipulative approaches to human brain dynamics

Manipulative approaches to human brain dynamics Book
Author : Keiichi Kitajo,Takashi Hanakawa, Risto Juhani Ilmoniemi,Carlo Miniussi
Publisher : Frontiers Media SA
Release : 2015-05-29
ISBN : 2889194795
Language : En, Es, Fr & De

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Book Description :

In this EBook, we highlight how newly emerging techniques for non-invasive manipulation of the human brain, combined with simultaneous recordings of neural activity, contribute to the understanding of brain functions and neural dynamics in humans. A growing body of evidence indicates that the neural dynamics (e.g., oscillations, synchrony) are important in mediating information processing and networking for various functions in the human brain. Most of previous studies on human brain dynamics, however, show correlative relationships between brain functions and patterns of neural dynamics measured by imaging methods such as electroencephalography (EEG), magnetoencephalography (MEG), near-infrared spectroscopy (NIRS), positron emission tomography (PET) and functional magnetic resonance imaging (fMRI). In contrast, manipulative approaches by non-invasive brain stimulation (NIBS) have been developed and extensively used. These approaches include transcranial magnetic stimulation (TMS) and transcranial electric stimulation (tES) such as transcranial direct current stimulation (tDCS), alternating current stimulation (tACS), and random noise stimulation (tRNS), which can directly manipulate neural dynamics in the intact human brain. Although the neural-correlate approach is a strong tool, we think that manipulative approaches have far greater potential to show causal roles of neural dynamics in human brain functions. There have been technical challenges with using manipulative methods together with imaging methods. However, thanks to recent technical developments, it has become possible to use combined methods such as TMS–EEG coregistration. We can now directly measure and manipulate neural dynamics and analyze functional consequences to show causal roles of neural dynamics in various brain functions. Moreover, these combined methods can probe brain excitability, plasticity and cortical networking associated with information processing in the intact human brain. The contributors to this EBook have succeeded in showcasing cutting-edge studies and demonstrate the huge impact of their approaches on many areas in human neuroscience and clinical applications.

Plasticity in the Adult Brain From Genes to Neurotherapy

Plasticity in the Adult Brain  From Genes to Neurotherapy Book
Author : M.A. Hofman,G.J. Boer,E.J.W. Van Someren,J. Verhaagen,D.F. Swaab,A.J.G.D. Holtmaat
Publisher : Elsevier
Release : 2002-10-23
ISBN : 008049773X
Language : En, Es, Fr & De

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Book Description :

In the past decade neuronal plasticity has become a major theme of modern neurobiology, from cellular and molecular mechanisms of synapse formation in worms and insects to behavioural recovery from strokes in elderly humans. For this reason the focus of interest in the present volume of Progress in Brain Research is on the topic of neuroplasticity in mature organisms, including humans. Contributions range from neurogenesis and synaptic plasticity in the adult primate brain, to neural mechanisms of learning and memory, and the influence of environmental factors and aging on the functional potential of the central nervous system. Several contributions focus on recent developments in neural regeneration and brain repair, providing challenging evidence that the use of stem cell neurotherapy may be beneficial to humans suffering from various neurological and psychiatric diseases. This volume integrates new information on the cellular and molecular mechanisms of neuroplasticity and highlights challenging future questions in this exciting and topical area of neuroscience.

Rhythms of the Brain

Rhythms of the Brain Book
Author : Gyorgy Buzsaki
Publisher : Oxford University Press
Release : 2011
ISBN : 0199828237
Language : En, Es, Fr & De

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Book Description :

Studies of mechanisms in the brain that allow complicated things to happen in a coordinated fashion have produced some of the most spectacular discoveries in neuroscience. This book provides eloquent support for the idea that spontaneous neuron activity, far from being mere noise, is actually the source of our cognitive abilities. It takes a fresh look at the coevolution of structure and function in the mammalian brain, illustrating how self-emerged oscillatory timing is the brain's fundamental organizer of neuronal information. The small-world-like connectivity of the cerebral cortex allows for global computation on multiple spatial and temporal scales. The perpetual interactions among the multiple network oscillators keep cortical systems in a highly sensitive metastable state and provide energy-efficient synchronizing mechanisms via weak links. In a sequence of cycles, György Buzsáki guides the reader from the physics of oscillations through neuronal assembly organization to complex cognitive processing and memory storage. His clear, fluid writing-accessible to any reader with some scientific knowledge-is supplemented by extensive footnotes and references that make it just as gratifying and instructive a read for the specialist. The coherent view of a single author who has been at the forefront of research in this exciting field, this volume is essential reading for anyone interested in our rapidly evolving understanding of the brain.

Slow Brain Oscillations of Sleep Resting State and Vigilance

Slow Brain Oscillations of Sleep  Resting State and Vigilance Book
Author : Anonim
Publisher : Elsevier
Release : 2011-08-13
ISBN : 0444538380
Language : En, Es, Fr & De

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Book Description :

This volume of Progress in Brain Research documents research presented at the 26th International Summer School of Brain Research (Amsterdam, Jun/Jul 2010) and looks at how the oscillations that characterize brain activity vary between task performance - the EEG power and performance modulations, rest - the MRI default mode and other networks, and sleep - the cortical slow oscillations. Studies over the past decade indicate that the study of these slow oscillations is essential for our understanding of plasticity, memory, brain structure from synapse to default mode network, cognition, consciousness and ultimately for our understanding of the mechanisms and functions of sleep and vigilance. Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Network Functions and Plasticity

Network Functions and Plasticity Book
Author : Jian Jing
Publisher : Academic Press
Release : 2017-04-11
ISBN : 0128034998
Language : En, Es, Fr & De

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Book Description :

Network Functions and Plasticity: Perspectives from Studying Neuronal Electrical Coupling in Microcircuits focuses on the specific roles of electrical coupling in tractable, well-defined circuits, highlighting current research that offers novel insights for electrical coupling‘s roles in sensory and motor functions, neural computations, decision-making, regulation of network activity, circuit development, and learning and memory. Bringing together a diverse group of international experts and their contributions using a variety of approaches to study different invertebrate and vertebrate model systems with a focus on the role of electrical coupling/gap junctions in microcircuits, this book presents a timely contribution for students and researchers alike. Provides an easy-to-read introduction on neural circuits of the model system Focuses on the specific roles of electrical coupling in tractable, well-defined circuits Includes recent discoveries and findings that are presented in the context of historical background Outlines outstanding issues and future research in the field

Emergent Brain Dynamics

Emergent Brain Dynamics Book
Author : April A. Benasich,Urs Ribary
Publisher : MIT Press
Release : 2018-07-31
ISBN : 0262038633
Language : En, Es, Fr & De

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Book Description :

Experts explore the maturation of nonlinear brain dynamics from a developmental perspective and consider the relationship of neurodevelopmental disorders to early disruption in dynamic coordination. This volume in the Strüngmann Forum Reports series explores the complex mechanisms that accompany the dynamic processes by which the brain evolves and matures. Integrating perspectives from multiple disciplines, the book identifies knowledge gaps and proposes innovative ways forward for this emerging area of cross-disciplinary study. The contributors examine maturation of nonlinear brain dynamics across systems from a developmental perspective and relate these organizing networks to the establishment of normative cognition and pathology seen in many neurodevelopmental disorders. The book looks at key mechanistic questions, including: What role does dynamic coordination play in the establishment and maintenance of brain networks and structural and functional connectivity? How are local and global functional networks assembled and transformed over normative development? To what degree do oscillatory patterns vary across development? What is the impact of critical periods, and which factors initiate and terminate such periods? It also explores the potential of new technologies and techniques to enhance understanding of normative development and to enable early identification and remediation of neurodevelopmental and neuropsychiatric disorders that may result from early disruption in dynamic coordination. Contributors Sylvain Baillet, Yehezkel Ben-Ari, April A. Benasich, Olivier Bertrand, Gyorgy Buzsáki, Alain Chédotal, Sam M. Doesburg, Gordin Fishell, Adriana Galván, Jennifer N. Gelinas, Jay Giedd, Pierre Gressens, Ileana L. Hanganu-Opatz, Rowshanak Hashemiyoon, Takao K. Hensch, Suzana Herculano-Houzel, Mark Hübener, Mark, Matthias Kaschube, Michael S. Kobor, Bryan Kolb, Thorsten Kolling, Jean-Philippe Lachaux, Ulman Lindenberger, Heiko J. Luhmann, Hannah Monyer, Sarah R. Moore, Charles A. Nelson III, Tomáš Paus, Patrick L. Purdon, Pasko Rakic, Urs Ribary, Akira Sawa, Terrence J. Sejnowski, Wolf Singer, Cheryl L. Sisk, Nicholas C. Spitzer, Michael P. Stryker, Migranka Sur, Peter J. Uhlhaas

Brain Oscillations in Human Communication

Brain Oscillations in Human Communication Book
Author : Anne Keitel,Johanna Rimmele,Sophie Molholm,Joachim Gross
Publisher : Frontiers Media SA
Release : 2018-04-20
ISBN : 2889454584
Language : En, Es, Fr & De

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Book Description :

Brain oscillations, or neural rhythms, reflect widespread functional connections between large-scale neural networks, as well as within cortical networks. As such they have been related to many aspects of human behaviour. An increasing number of studies have demonstrated the role of brain oscillations at distinct frequency bands in cognitive, sensory and motor tasks. Consequentially, those rhythms also affect diverse aspects of human communication. On the one hand, this comprises verbal communication; a field where the understanding of neural mechanisms has seen huge advances in recent years. Speech is inherently organised in a rhythmic manner. For example, time scales of phonemes and syllables, but also formal prosodic aspects such as intonation and stress, fall into distinct frequency bands. Likewise, neural rhythms in the brain play a role in speech segmentation and coding of continuous speech at multiple time scales, as well as in the production of speech. On the other hand, human communication involves widespread and diverse nonverbal aspects where the role of neural rhythms is far less understood. This can be the enhancement of speech processing through visual signals, thought to be guided via brain oscillations, or the conveying of emotion, which results in differential rhythmic modulations in the observer. Additionally, body movements and gestures often have a communicative purpose and are known to modulate sensorimotor rhythms in the observer. This Research Topic of Frontiers in Human Neuroscience highlights the diverse aspects of human communication that are shaped by rhythmic activity in the brain. Relevant contributions are presented from various fields including cognitive and social neuroscience, neuropsychiatry, and methodology. As such they provide important new insights into verbal and non-verbal communication, pathological changes, and methodological innovations.

Advances in Psychology Research

Advances in Psychology Research Book
Author : Alexandra Columbus
Publisher : Nova Publishers
Release : 2008
ISBN : 9781600219245
Language : En, Es, Fr & De

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Book Description :

Presents original research results on the leading edge of psychology research. Each article has been carefully selected in an attempt to present substantial research results across a broad spectrum.

Understanding Dynamical Interactions in the Hippocampus

Understanding Dynamical Interactions in the Hippocampus Book
Author : Jack N. Waddell
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Understanding Dynamical Interactions in the Hippocampus book written by Jack N. Waddell, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Electric Brain

Electric Brain Book
Author : R. Douglas Fields
Publisher : BenBella Books
Release : 2020-02-04
ISBN : 1948836297
Language : En, Es, Fr & De

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Book Description :

What is as unique as your fingerprints and more revealing than your diary? Hint: Your body is emitting them right now and has been every single day of your life. Brainwaves. Analyzing brainwaves, the imperceptible waves of electricity surging across your scalp, has been possible for nearly a century. But only now are neuroscientists becoming aware of the wealth of information brainwaves hold about a person's life, thoughts, and future health. From the moment a reclusive German doctor discovered waves of electricity radiating from the heads of his patients in the 1920s, brainwaves have sparked astonishment and intrigue, yet the significance of the discovery and its momentous implications have been poorly understood. Now, it is clear that these silent broadcasts can actually reveal a stunning wealth of information about any one of us. In Electric Brain, world-renowned neuroscientist and author R. Douglas Fields takes us on an enthralling journey into the world of brainwaves, detailing how new brain science could fundamentally change society, separating fact from hyperbole along the way. In this eye-opening and in-depth look at the most recent findings in brain science, Fields explores groundbreaking research that shows brainwaves can: • Reveal the type of brain you have—its strengths and weaknesses and your aptitude for learning different types of information • Allow scientists to watch your brain learn, glean your intelligence, and even tell how adventurous you are • Expose hidden dysfunctions—including signifiers of mental illness and neurological disorders • Render your thoughts and transmit them to machines and back from machines into your brain • Meld minds by telepathically transmitting information from one brain to another • Enable individuals to rewire their own brains and improve cognitive performance Written by one of the neuroscientists on the cutting edge of brainwave research, Electric Brain tells a fascinating and obscure story of discovery, explains the latest science, and looks to the future—and the exciting possibilities in store for medicine, technology, and our understanding of ourselves.

Cortical Oscillations in Health and Disease

Cortical Oscillations in Health and Disease Book
Author : Roger D. Traub,Miles A. Whittington
Publisher : Oxford University Press, USA
Release : 2010
ISBN : 0195342798
Language : En, Es, Fr & De

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Book Description :

This book first reviews the case that brain oscillations not only are important for cognition, as long suspected, but also play a part in the expression of signs and symptoms of neuropsychiatric disorders. The cellular mechanisms of many of the clinically relevant oscillations have been studied by the authors and their colleagues, using in vitro slice methods as well as detailed computer simulations. A surprising insight is that gap junctions between principal neurons play an absolutely critical role in so many types of oscillation in neuronal populations; oscillations are not just the result of properties of individual neurons and their synaptic connections. Furthermore, the way in which gap junctions produce oscillations in the cortex is novel, involving as it does global properties of networks, rather than just the time constants of membrane currents. This insight has implications for therapeutics as well as for our understanding of normal brain functions.

The Neurobiology of Childhood

The Neurobiology of Childhood Book
Author : Susan L. Andersen,Daniel S. Pine
Publisher : Springer
Release : 2014-05-13
ISBN : 3642549136
Language : En, Es, Fr & De

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Book Description :

During the past years there has been rapid progress in the understanding of how early life stress impacts psychopathology in children. The first two parts of this book present the basic principles of brain development and describe the most important neuronal systems. This includes systems involved in emotion processing, cognitive control, and social processes. These first two general sections are followed by an overview about recent research on various neuronal and psychiatric disorders, where environmental exposures and altered brain development play an important role: sleep, autism, ADHD and other developmental forms of psychopathology.

Biomag 96

Biomag 96 Book
Author : Cheryl J. Aine,Yoshio Okada,Gerhard Stroink,Stephen J. Swithenby,Charles C. Wood
Publisher : Springer Science & Business Media
Release : 2013-11-11
ISBN : 146121260X
Language : En, Es, Fr & De

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Book Description :

A modified Linear Estimation Approach was performed to reconstruct current sources within the heart. Based on MRI data sets the Boundary Element Method was used to create tailored multicompartment models of the human thorax which were used to solve the forward problem of magnetocardiography. The ability of the proposed method was demonstrated for the localization of a single current dipole as an example of a focal source. By means of introducing small shiftings to all reconstruction dipoles during linear estimation solution as well as performing a successive focussing strategy ignoring places without significant electrical activity the method could easily be extended to the reconstruction of real 3D sources. Based on a special minimum-norm solution the source volume can be estimated applying a finite element approximation using cube elements. The size of an extended current source can be estimated by superimposing the reconstructed dipoles to an equivalent dipole and comparing the corresponding volume with the sphere which would be related to the equivalent dipole. The deviation of these volumes can be taken as a criterion for non-dipolarity of sources.

Adaptive Processing of Brain Signals

Adaptive Processing of Brain Signals Book
Author : Saeid Sanei
Publisher : John Wiley & Sons
Release : 2013-05-28
ISBN : 1118622146
Language : En, Es, Fr & De

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Book Description :

In this book, the field of adaptive learning and processing is extended to arguably one of its most important contexts which is the understanding and analysis of brain signals. No attempt is made to comment on physiological aspects of brain activity; instead, signal processing methods are developed and used to assist clinical findings. Recent developments in detection, estimation and separation of diagnostic cues from different modality neuroimaging systems are discussed. These include constrained nonlinear signal processing techniques which incorporate sparsity, nonstationarity, multimodal data, and multiway techniques. Key features: Covers advanced and adaptive signal processing techniques for the processing of electroencephalography (EEG) and magneto-encephalography (MEG) signals, and their correlation to the corresponding functional magnetic resonance imaging (fMRI) Provides advanced tools for the detection, monitoring, separation, localising and understanding of functional, anatomical, and physiological abnormalities of the brain Puts a major emphasis on brain dynamics and how this can be evaluated for the assessment of brain activity in various states such as for brain-computer interfacing emotions and mental fatigue analysis Focuses on multimodal and multiway adaptive processing of brain signals, the new direction of brain signal research

Spike timing dependent plasticity

Spike timing dependent plasticity Book
Author : Henry Markram,Wulfram Gerstner,Per Jesper Sjöström
Publisher : Frontiers E-books
Release : 2021-12-03
ISBN : 2889190439
Language : En, Es, Fr & De

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Book Description :

Hebb's postulate provided a crucial framework to understand synaptic alterations underlying learning and memory. Hebb's theory proposed that neurons that fire together, also wire together, which provided the logical framework for the strengthening of synapses. Weakening of synapses was however addressed by "not being strengthened", and it was only later that the active decrease of synaptic strength was introduced through the discovery of long-term depression caused by low frequency stimulation of the presynaptic neuron. In 1994, it was found that the precise relative timing of pre and postynaptic spikes determined not only the magnitude, but also the direction of synaptic alterations when two neurons are active together. Neurons that fire together may therefore not necessarily wire together if the precise timing of the spikes involved are not tighly correlated. In the subsequent 15 years, Spike Timing Dependent Plasticity (STDP) has been found in multiple brain brain regions and in many different species. The size and shape of the time windows in which positive and negative changes can be made vary for different brain regions, but the core principle of spike timing dependent changes remain. A large number of theoretical studies have also been conducted during this period that explore the computational function of this driving principle and STDP algorithms have become the main learning algorithm when modeling neural networks. This Research Topic will bring together all the key experimental and theoretical research on STDP.

Sleep and Chronobiology in Plasticity and Memory

Sleep and Chronobiology in Plasticity and Memory Book
Author : Jason Robert Gerstner,H. Craig Heller,Sara J. Aton
Publisher : Frontiers Media SA
Release : 2016-01-15
ISBN : 2889197468
Language : En, Es, Fr & De

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Book Description :

Chronobiological mechanisms regulating time-of-day mediated behaviors, such as sleep and circadian rhythms, are thought to interact with and/or share cellular and molecular signaling cascades that shape synaptic plasticity and neural excitability. These same factors are also known to underlie events that govern higher-order cognitive processing, including learning and memory formation, and often through phylogenetically conserved pathways. This suggests that factors which contribute to adaptive responses to changing environmental stimuli are likely derived from basic evolutionarily ancient processes, and underscores the importance of using both invertebrate and vertebrate models to study the interaction of chronobiology and cognitive processing. This issue highlights current views along with original research on sleep and circadian features of plasticity and memory in multiple species, models, and systems.

Non Invasive Brain Stimulation in the Study and Modulation of Metaplasticity in Neurological Disorders

Non Invasive Brain Stimulation in the Study and Modulation of Metaplasticity in Neurological Disorders Book
Author : Mariagiovanna Cantone,Giuseppe Lanza,Federico Ranieri,George M. Opie,Carmen Terranova
Publisher : Frontiers Media SA
Release : 2021-09-03
ISBN : 2889712605
Language : En, Es, Fr & De

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Book Description :

Download Non Invasive Brain Stimulation in the Study and Modulation of Metaplasticity in Neurological Disorders book written by Mariagiovanna Cantone,Giuseppe Lanza,Federico Ranieri,George M. Opie,Carmen Terranova, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Calculations E Book

Clinical Calculations   E Book Book
Author : Joyce LeFever Kee,Sally M. Marshall,Mary Catherine Forrester,Kathryn Woods
Publisher : Elsevier Health Sciences
Release : 2020-06-12
ISBN : 0323674224
Language : En, Es, Fr & De

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Book Description :

Learn to calculate drug dosages safely, accurately, and easily with Kee’s Clinical Calculations, 9th Edition! This market-leading text covers all four major drug calculation methods, including ratio & proportion, formula, fractional equation, and dimensional analysis. It also includes practice problems for both general care as well as specialty areas such as pediatrics, labor and delivery, critical care, and community nursing. With its market-leading, comprehensive coverage; strong emphasis on patient safety; and the incorporation of the latest information on antidiabetic agents, anticoagulant agents, drug administration techniques, and devices; Kee remains the winning choice for easy drug calculation mastery. Coverage of all four major drug calculation methods includes ratio & proportion, formula, fractional equation, and dimensional analysis to help you learn and apply the method that works best for you. The latest information on drug administration techniques and devices helps you master the most up-to-date techniques of drug administration, including oral, intravenous, intra-muscular, subcutaneous, and other routes. Caution boxes provide alerts to problems or issues related to various drugs and their administration. Information on infusion pumps covers enteral, single, multi-channel, PCA, and insulin; and explains their use in drug administration. Calculations for Specialty Areas section addresses the drug calculations needed to practice in pediatric, critical care, labor and delivery, and community settings. Detailed, full-color photos and illustrations show the most current equipment for IV therapy, the latest types of pumps, and the newest syringes. Comprehensive post-test lets you test your knowledge of key concepts from the text. NEW! Updated information on Antidiabetic Agents (orals and injectables) has been added throughout the text where appropriate. NEW! Updated content on Anticoagulant Agents is housed in an all-new chapter. NEW! Colorized abbreviations for the four methods of calculation (BF, RP, FE, and DA) appear in the Example Problems sections. NEW! Updated content and patient safety guidelines throughout the text reflects the latest practices and procedures. NEW! Updated practice problems across the text incorporate the latest drugs and dosages.

Neural Networks Artificial Intelligence and Industrial Applications

Neural Networks  Artificial Intelligence and Industrial Applications Book
Author : Bert Kappen,Stan Gielen
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1447130871
Language : En, Es, Fr & De

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Book Description :

Neural networks is a field of research which has enjoyed rapid expansion in both the academic and industrial research communities. This volume contains papers presented at the Third Annual SNN Symposium on Neural Networks to be held in Nijmegen, The Netherlands, 14 - 15 September 1995. The papers are divided into two sections: the first gives an overview of new developments in neurobiology, the cognitive sciences, robotics, vision and data modelling. The second presents working neural network solutions to real industrial problems, including process control, finance and marketing. The resulting volume gives a comprehensive view of the state of the art in 1995 and will provide essential reading for postgraduate students and academic/industrial researchers.