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Brain Lipids In Synaptic Function And Neurological Disease

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Brain Lipids in Synaptic Function and Neurological Disease

Brain Lipids in Synaptic Function and Neurological Disease Book
Author : Jacques Fantini,Nouara Yahi
Publisher : Academic Press
Release : 2015-05-12
ISBN : 0128004924
Language : En, Es, Fr & De

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Book Description :

Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer’s, Creutzfeldt-Jakob’s and Parkinson’s. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders. Written to provide a "hands-on" approach for readers Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings Step-by-step guide to memorize and draw lipid structures Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique

Omega 3 Fatty Acids in Brain and Neurological Health

Omega 3 Fatty Acids in Brain and Neurological Health Book
Author : Ronald Ross Watson,Fabien De Meester
Publisher : Elsevier
Release : 2014-06-25
ISBN : 0124105475
Language : En, Es, Fr & De

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Book Description :

Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. Omega-3 Fatty Acids in Brain and Neurological Health is the first book to focus exclusively on the role of omega-3 fatty acids on general brain health. The articles in this collection illustrate omega-3 fatty acids' importance in longevity, cognitive impairment, and structure and function of the brain's neurons. Research has established links between omega-3 fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis. This book encompasses some of the most recent research, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep, and neurodegenerative diseases. This collection helps to push research forward toward a complete understanding of omega-3 fatty acids' relationship to brain and neurological health. The first book-length collection of original research on the connection between omega-3 fatty acids and the brain Provides a comprehensive introduction to the state of research on omega-3 fatty acids and the brain and directions for future research A foundational collection for neuroscience, neurology, and nutrition research

Lipid Mediators and Their Metabolism in the Brain

Lipid Mediators and Their Metabolism in the Brain Book
Author : Akhlaq A. Farooqui
Publisher : Springer Science & Business Media
Release : 2011-08-12
ISBN : 9781441999405
Language : En, Es, Fr & De

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Book Description :

Lipid Mediators and Their Metabolism in the Brain presents readers with cutting edge and comprehensive information not only on the synthesis and degradation of glycerophospholipid-, sphingolipid-, and cholesterol-derived lipid mediators, but also their involvement in neurological disorders. It is hoped that this monograph will be useful not only to postgraduate student and their teachers, but also to research scientists and physicians, who are curious about the generation and roles of lipid mediators in the brain.

Pharmacological Modification of Excitatory Hippocampal Ca1 Synapses in Pathological Models of Neuroinflammation and Alzheimer s Disease

Pharmacological Modification of Excitatory Hippocampal Ca1 Synapses in Pathological Models of Neuroinflammation and Alzheimer s Disease Book
Author : Keng-Yu Chang
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"An integral component of synaptic transmission is the capacity of synapses to adjust their structural and functional properties in response to the activities of other neurons in a process called synaptic plasticity. Changes in excitatory synapses can occur on dendritic spines, postsynaptic sites of the majority of excitatory synapses in the brain. In many neurodegenerative diseases, dendritic spine dysgenesis is observed; thus knowing what causes spine abnormalities will aid the development of therapies against these diseases. Recent studies suggest that neuroinflammation contributes to many neurological disorders such as, Alzheimer's disease (AD). Therefore, targeting neuroinflammation may be a viable way against different neurodegenerative diseases in addition to the use of cognitive enhancers. The goal of my thesis is to understand how spines are affected in neurodegenerative diseases and develop effective methods to prevent and promote the recovery in diseased brains. To address this problem, I have used a multidisciplinary approach to examine structural and functional changes of the CA3-CA1 excitatory synapses in the hippocampus during neuroinflammation and the addition of cognitive enhancing compound. The specific aims of my doctoral thesis work are as follows:AIM 1: To understand effect of lipid homeostasis on synaptic structure and function in a neuroinflammation model. Since neuroinflammation is an important contributor of various neurological diseases, I focused on how the neuronal circuitry will be affected during incidences of neuroinflammation and how can this be corrected. I found that in lipopolysaccharide (LPS)-mediated model of neuroinflammation, there is an abnormal lipid aggregation in the form of lipid bodies (LBs), disruption in mitochondrial function, changes in spine morphology and synaptic transmission. The addition of the polyunsaturated fatty acid, docosahexanoic acid (DHA) prevents LPS-associated deficits. My findings suggest that DHA supplementation may provide an attractive multiple-pronged approach in counteracting cellular damage caused by neuroinflammation. AIM 2: To understand effect of pharmacological inhibition of aromatase on synaptic structure and function in during oligomeric beta-amyloid42 (Abeta42)-mediated toxicity. Epidemiological studies revealed that pharmacological inhibition of estrogen synthesis through the use of aromatase inhibitors, such as letrozole, for the post-operative treatment of hormonally-responsive breast cancer also increases the incidences of cognitive decline in patients with unknown reasons. Interestingly, I found that inhibition of hippocampal local estrogen synthesis with letrozole disrupts mitochondrial homeostasis and decreases dendritic spines and synaptic proteins. These deficits are exacerbated in the presence of oligomeric Abeta42-mediated toxicity. My findings may explain why letrozole users have higher chances of cognitive impairments and that off-target effects of aromatase inhibition in the brain must be carefully considered. AIM 3: To study the effect of long-term pharmacological cognitive enhancement using ampakines on synaptic structure and function. In line with current believes, direct enhancement of synaptic transmission can be used as a therapeutic method to target ailing neuronal communication observed in neurodegenerative diseases. I found that chronically enhancing AMPA receptors using the ampakine, CX546, surprisingly causes a decrease in dendritic spine densities and excitatory synaptic transmission that is accompanied by a concurrent enhancement of synaptic efficacy and plasticity. My findings provide a mechanistic explanation, at the synaptic structural and functional level, for the cognitive enhancing ability of chronic ampakine treatment.Findings presented in my doctoral thesis contribute to our understanding how the brain responds to neuroinflammation pathologies and cognitive enhancing compounds." --

Update on Dementia

Update on Dementia Book
Author : Davide Moretti
Publisher : BoD – Books on Demand
Release : 2016-09-28
ISBN : 9535126547
Language : En, Es, Fr & De

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Book Description :

The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma and discrimination should be promoted. The common efforts and the final aim will have to be the progress of a ''dementia-constructive'' world, where people with dementia can take advantage of equal opportunities.

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases

Role of the Mediterranean Diet in the Brain and Neurodegenerative Diseases Book
Author : Tahira Farooqui,Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2017-10-24
ISBN : 0128119608
Language : En, Es, Fr & De

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Book Description :

Role of the Mediterranean Diet in the Brain and Neurodegenerative Disease provides a comprehensive overview of the effects of all components of the Mediterranean diet on the brain, along with its beneficial effects in neurodegenerative diseases. It covers topics on neurodegenerative diseases (Alzheimer disease (AD), Parkinson disease, (PD) Huntington disease (HD) and Amyotrophic Lateral Sclerosis (ALS), also providing information on how cardiovascular disease, Type 2 Diabetes, and Metabolic Syndrome become risk factors for neurodegenerative diseases. This book focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative diseases as well as signal transduction. The Mediterranean diet is characterized by the abundant consumption of olive oil, high consumption of plant foods (fruits, vegetables, pulses, cereals, nuts and seeds); frequent and moderate intake of wine (mainly with meals); moderate consumption of fish, seafood, yogurt, cheese, poultry and eggs; and low consumption of red meat and processed meat products. High consumption of dietary fiber, low glycemic index and glycemic load, anti-inflammatory effects, and antioxidant compounds may act together to produce favorable effects on health status. Collective evidence suggests that Mediterranean diet not only increases longevity by lowering cardiovascular disease, inhibiting cancer growth, but also by protecting the body from age-dependent cognitive decline. Comprehensively provides an overview of the effects of the Mediterranean diet on the brain and its beneficial effects in neurodegenerative diseases Discusses the relationship among Type 2 Diabetes, Metabolic Syndrome and Alzheimer's Disease, and the effect of the Mediterranean diet on normal aging, longevity, and other neurodegenerative diseases Focuses on how the Mediterranean diet suppresses oxidative stress and neuroinflammation in neurodegenerative disease

Brain Lipids and Cholesterol in Neuropsychiatric Disorders

Brain Lipids and Cholesterol in Neuropsychiatric Disorders Book
Author : Erika Freemantle
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Neuropsychiatric disorders and suicidal behaviour represent major contributions to mortality in Canada. Among the many factors associated with psychiatric disorders and suicide, alterations in lipids and cholesterol have been demonstrated both peripherally and centrally, supporting their roles as mediating variables in the underlying neuropathology. Cholesterol (CHL) regulation is a complex and dynamic system, and while animal studies also support a mediating role of CHL on brain function, efforts to determine a biological association in humans have achieved only modest gains. While mechanisms governing cholesterol regulation are not entirely understood, cholesterol is well accepted to have important impacts on a variety of brain functions from neurotransmission to synaptic plasticity and neurodegeneration, with unique contributions from neurons, astrocytes, and oligodendrocytes. Given the extensive regulatory feedback mechanisms and the implications in neurological function, determining a biological basis for the association of cholesterol with neuropsychiatric disorders remains an important area of research. This research aimed to explore the neurobiological mechanism whereby alterations in CHL may relate to neuropsychiatric phenotypes. The results presented in chapter 3 suggest, while no clear differences were found in suicide completers with major depressive disorder, expression of several CHL related genes associate more strongly with white matter CHL levels compared to grey matter, suggesting a potential contribution of SORT1, LPL, and ABCA2, in the regulation of white matter CHL. The results of chapter 4 suggest altered phospholipid levels and expression of lysosomal acid lipase A gene in violent suicides in the prefrontal cortex, which would have important consequences for inhibitory neurotransmission. The results of chapter 4 suggest an increase in 24-hydroxycholesterol in the prefrontal cortex of suicide completers and this could have implications for synapse maintenance and loss in the neuropathology of suicide. In regards to CHL levels, however, little evidence in support of alterations in CNS CHL in neuropsychiatric disorders and suicidal behaviour was noted." --

The Role of Glycosylation in Health and Disease

The Role of Glycosylation in Health and Disease Book
Author : Gordan Lauc,Irena Trbojević-Akmačić
Publisher : Springer Nature
Release : 2021-09-08
ISBN : 3030701158
Language : En, Es, Fr & De

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Book Description :

Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research. Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans. The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.

Sterol Regulation of Ion Channels

Sterol Regulation of Ion Channels Book
Author : Anonim
Publisher : Academic Press
Release : 2017-08-29
ISBN : 0128096209
Language : En, Es, Fr & De

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Book Description :

Sterol Regulation of Ion Channels, Volume 80, the latest in the Current Topics in Membranes series provides outstanding content to the scientific community on relevant topics that relate to the broad field of membranes. Topics of note in this new release include Membrane structure and general mechanisms of sterol regulation of ion channels, the Regulation of ion channels by sterols as boundary lipids, the Differential effects of sterols on ion channels: specific vs. non-specific interactions, the Structural determinants of cholesterol-ion channels interactions, and the Regulation of Ca2+-sensitive K+ channels by cholesterol and bile acids via distinct channel subunits and sites, amongst other specialized chapters. The serial is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes Contains original material, both textual and illustrative, that make it a very relevant reference Presented in a very comprehensive manner Ideal for both researchers in the field and general readers

Membrane Proteins

Membrane Proteins Book
Author : Rossen Donev
Publisher : Academic Press
Release : 2022-01-13
ISBN : 0323988962
Language : En, Es, Fr & De

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Book Description :

Membrane Proteins, Volume 128 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Protein Chemistry and Structural Biology series Updated release includes the latest information on the membrane proteins

Curcumin for Neurological and Psychiatric Disorders

Curcumin for Neurological and Psychiatric Disorders Book
Author : Tahira Farooqui,Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2019-03-16
ISBN : 0128154624
Language : En, Es, Fr & De

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Book Description :

Curcumin for Neurological and Psychiatric Disorders: Neurochemical and Pharmacological Properties focuses on the different molecular mechanisms underlying curcumin-mediated beneficial effects in neurological diseases. The book's editors discuss the neurochemical and pharmacological properties of curcumin, followed by the effect of curcumin in neurotraumatic diseases, neurodegenerative diseases, and neuropsychiatric diseases. The book also offers a perspective on future studies on the treatment of neurological disorders. The beneficial effects of curcumin have been observed both in cultured cells and in animal models, thus paving the way for ongoing present and future human clinical trials. Curcumin produces antioxidant and anti-inflammatory effects not only by blocking oxidative stress and neuroinflammation in neurotraumatic and neurodegenerative diseases, but also by restoring cellular homeostasis and rebalancing redox equilibrium. Identifies molecular mechanisms of curcumin effects in neurological diseases Includes effects on neurotraumatic, neurodegenerative and psychiatric diseases Covers the antioxidant, anti-inflammatory and immunomodulatory effects of curcumin Examines curcumin’s potential in developing new therapeutic drugs

Biochemical Factors Concerned in the Functional Activity of the Nervous System

Biochemical Factors Concerned in the Functional Activity of the Nervous System Book
Author : D. Richter
Publisher : Elsevier
Release : 2013-10-22
ISBN : 1483138488
Language : En, Es, Fr & De

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Book Description :

Biochemical Factors Concerned in the Functional Activity of the Nervous System presents the biological aspects concerned in the functional activity of the nervous system. This book covers several interesting topics concerning the central nervous system, including phospholipids, RNA synthesis, nerve impulse flow, and nerve growth factor. Comprised of 213 chapters, this book begins with an overview of the electron micrographs of calcium–ATP–phospholipid complexes. This text then examines the biochemical and histochemical studies on sectioned rat spinal cords, which demonstrated two types of monoamine-reducing drugs. Other chapters consider the diversity of antagonistic relations between the thiamine derivatives and vitamin B6, which is manifested by changes in the glutamate–GABA, histidine–histamine, tryptophan–serotonin, and tyrosine–noradrenaline systems. This book discusses as well the influence of a conditioned avoidance training experience on the incorporation of radioactive uridine into the RNA of mouse brain. The final chapter deals with the amino acid-incorporating activity of cerebral polyribosomes. This book is a valuable resource for biochemists, neurologists, pharmacologists, and biophysicists.

Molecular Organization of Membranes Where Biology Meets Biophysics

Molecular Organization of Membranes  Where Biology Meets Biophysics Book
Author : Marek Cebecauer,David Holowka
Publisher : Frontiers Media SA
Release : 2018-02-07
ISBN : 2889454096
Language : En, Es, Fr & De

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Book Description :

Biological membranes protect cells and organelles from the surrounding environment, but serve also as organising platforms for physiological processes such as cell signalling. The hydrophobic core of membranes is composed of lipids and proteins influencing each other. Local membrane composition and properties define its molecular organisation and, in this way, regulate the function of all associated molecules. Therefore, studying interactions of components, biophysical properties and overall membrane dynamics provides essential information on its function in the context of cell activities. Such knowledge can contribute to biomedical fields such as pharmacology, immunology, neurobiology and many others. The goal of the Research Topic entitled ‘Molecular organisation of membranes: where biology meets biophysics’ was to provide a comprehensive platform for publishing articles, reviews and opinions focused on membrane organisation and the forces behind its heterogeneous and dynamic structure. We collected 11 works which cover topics as diverse as general membrane organisation models, membrane trafficking and signalling regulation, biogenesis of caveolae, protein-lipid interactions and the importance of membrane-associated tetraspanins networks. The prevalent theme was the existence of membrane nanodomains. To this point, new emerging technologies are presented which own the power to bring a novel insight on how membrane nanodomains are formed and maintained and what is their function. We believe that the collection of works in this Research Topic brings forward some important questions which will stimulate further research in this difficult but exciting field.

Trace Amines and Neurological Disorders

Trace Amines and Neurological Disorders Book
Author : Tahira Farooqui,Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2016-07-12
ISBN : 0128036168
Language : En, Es, Fr & De

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Book Description :

Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders. Focuses on recent findings on trace amines, providing insights into the functional significance, molecular mechanisms, and biological relevance of TAARS in neurological disorders Edited work with chapters authored by leaders in the field from around the globe, the broadest, most expert coverage available Provides cutting-edge research on trace amines-mediated signaling in vertebrate model systems

Glycosphingolipids Signaling

Glycosphingolipids Signaling Book
Author : Cheorl-Ho Kim
Publisher : Springer Nature
Release : 2021-01-23
ISBN : 9811558078
Language : En, Es, Fr & De

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Book Description :

This book presents the latest knowledge and the most recent research results on glycosphingolipid (GSL)-mediated signaling. GSLs are important constituents of the plasma membrane that exert their distinct functions through binding to certain functional proteins. They play a role in various human diseases and also function as human alloantigens. Cellular GSLs are associated with many biological functions such as cellular oncotransformation, phenotype change, neuronal or embryonic development, regulation of cell division, cell–cell interaction, cell attachment, adhesion, and motility, and intracellular signaling via protein–carbohydrate or carbohydrate–carbohydrate interactions. This book opens by providing the key background on GSL glycan–receptor interactions and mammalian GSL synthesis. Up-to-date information is then presented on all aspects of GSL-dependent signaling. Viral protein and bacterial toxin protein interactions with host cell GSLs are examined in depth, and the concluding chapter is devoted to signaling regulation. The book should assist in the further development of new strategies against emerging infectious agents and intractable diseases.

Food for the Ageing Population

Food for the Ageing Population Book
Author : Monique Raats
Publisher : Elsevier
Release : 2008-12-17
ISBN : 1845695488
Language : En, Es, Fr & De

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Book Description :

The world’s ageing population is increasing and food professionals will have to address the needs of older generations more closely in the future. This unique volume reviews the characteristics of the ageing population as food consumers, the role of nutrition in healthy ageing and the design of food products and services for the elderly. Chapters in part one discuss aspects of the elderly’s relationship with food such as appetite and ageing, ageing and sensory perception, food and satisfaction with life, and the social significance of meals. The second part of the book reviews the role of nutrition in extending functionality into later years, with chapters on topics such as undernutrition and conditions such as Alzheimer's disease, bone and joint health and eye-related disorders. Concluding chapters address the issues of food safety and the elderly, designing new foods and beverages for the ageing and nutrition education programmes. With its distinguished editors and contributors, Food for the ageing population is an essential reference for those involved in the research, development and provision of food products for the older generation. A unique review of the chararacteristics of the ageing population as food consumers Discusses aspects of the elderlys relationship with food, including appetite, ageing and sensory perception and the social significance of meals Examines the role of nutrition in extending functionality in later years, focusing on undernutrition, Alzheimers and bone and joint health

Diet and Exercise in Cognitive Function and Neurological Diseases

Diet and Exercise in Cognitive Function and Neurological Diseases Book
Author : Akhlaq A. Farooqui,Tahira Farooqui
Publisher : John Wiley & Sons
Release : 2015-03-23
ISBN : 1118840550
Language : En, Es, Fr & De

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Book Description :

Diet and Exercise in Cognitive Function and Neurological Diseases looks at the role and impact that nutrition and activity have on cognitive function and neurological health. The book is divided into the two sections. The first focuses on diet and its impact on neurobiological processes. Chapters focus on the impacts of specific diets, such as the Mediterranean diet, ketogenic and vegan diets, as well as the role specific nutrients, fats, fatty acids, and caloric intake have on neurological health and cognitive function. The second part of the book focuses on exercise, and its role in maintaining cognitive function, reducing neuroinflammatory responses, regulating adult neurogenesis, and healthy brain aging. Other chapters in this section look at the impacts of disease in the management of specific neurological disorders such multiple sclerosis and Parkinson’s disease. Collectively, the chapters in Diet and Exercise in Cognitive Function and Neurological Diseases come together to form a timely reference on the neurobiological interplay between diet and exercise on long-term brain health and cognitive function.

Handbook of Neurochemistry

Handbook of Neurochemistry Book
Author : Abel Lajtha
Publisher : Unknown
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Handbook of Neurochemistry book written by Abel Lajtha, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders

Insulin Resistance As a Risk Factor in Visceral and Neurological Disorders Book
Author : Akhlaq A. Farooqui
Publisher : Academic Press
Release : 2020-03
ISBN : 0128196033
Language : En, Es, Fr & De

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Book Description :

Insulin Resistance as a Risk Factor in Visceral and Neurological Disorders provides an overview on the risk factors for insulin resistance in visceral and neurological disorders. The book focuses on molecular mechanisms and signal transduction processes associated with the links. The comprehensive information in this monograph will not only help in the early detection of insulin resistance related visceral and neurological disorders, but also promote the discovery of new drugs which may block or delay onset in elderly patients. Understanding these processes is important not only for patients, caregivers and health professionals, but also for health policymakers who must plan for national resources.

Research Awards Index

Research Awards Index Book
Author : Anonim
Publisher : Unknown
Release : 1984
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Research Awards Index book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.