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Bone Repair Biomaterials

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Bone Repair Biomaterials

Bone Repair Biomaterials Book
Author : J A Planell,S M Best,D Lacroix,A Merolli
Publisher : Elsevier
Release : 2009-08-26
ISBN : 1845696611
Language : En, Es, Fr & De

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Book Description :

Bone repair is a fundamental part of the rapidly expanding medical care sector and has benefited from many recent technological developments. With an increasing number of technologies available, it is vital that the correct technique is selected for specific clinical procedures. This unique book will provide a comprehensive review of the materials science, engineering principles and recent advances in this important area. The first part of the book reviews the fundamentals of bone repair and regeneration. Chapters in the second part discuss the science and properties of biomaterials used for bone repair such as metals, ceramics, polymers and composites. The final section of the book discusses clinical applications and considerations with chapters on such topics as orthopaedic surgery, tissue engineering, implant retrieval and ethics of bone repair biomaterials. With its distinguished editors and team of international contributors, Bone repair biomaterials is an invaluable reference for researchers and clinicians within the biomedical industry and academia. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Reviews the fundamentals of bone repair and regeneration addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair with specific chapters assessing metals, ceramics, polymers and composites

Bone Repair Biomaterials

Bone Repair Biomaterials Book
Author : Kendell Pawelec,J. A. Planell
Publisher : Woodhead Publishing
Release : 2018-11-29
ISBN : 0081024525
Language : En, Es, Fr & De

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Book Description :

Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

Bone Substitute Biomaterials

Bone Substitute Biomaterials Book
Author : K. Mallick
Publisher : Elsevier
Release : 2014-08-05
ISBN : 0857099035
Language : En, Es, Fr & De

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Book Description :

Bone substitute biomaterials are fundamental to the biomedical sector, and have recently benefitted from extensive research and technological advances aimed at minimizing failure rates and reducing the need for further surgery. This book reviews these developments, with a particular focus on the desirable properties for bone substitute materials and their potential to encourage bone repair and regeneration. Part I covers the principles of bone substitute biomaterials for medical applications. One chapter reviews the quantification of bone mechanics at the whole-bone, micro-scale, and non-scale levels, while others discuss biomineralization, osteoductivization, materials to fill bone defects, and bioresorbable materials. Part II focuses on biomaterials as scaffolds and implants, including multi-functional scaffolds, bioceramics, and titanium-based foams. Finally, Part III reviews further materials with the potential to encourage bone repair and regeneration, including cartilage grafts, chitosan, inorganic polymer composites, and marine organisms. Provides a detailed and accurate overview of the bone substitute biomaterials, a fundamental part of the biomaterials and biomedical sector Provides readers with the principles of bone substitute biomaterials Reviews biomaterials for bone regeneration

A Tissue Regeneration Approach to Bone and Cartilage Repair

A Tissue Regeneration Approach to Bone and Cartilage Repair Book
Author : Hala Zreiqat,Colin R. Dunstan,Vicki Rosen
Publisher : Springer
Release : 2014-12-05
ISBN : 3319132660
Language : En, Es, Fr & De

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Book Description :

Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration. Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues. This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.

Bioactive Materials for Bone Regeneration

Bioactive Materials for Bone Regeneration Book
Author : Jiang Chang,Xingdong Zhang,Kerong Dai
Publisher : Academic Press
Release : 2020-02-28
ISBN : 0128135042
Language : En, Es, Fr & De

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Book Description :

Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments

Bone Tissue Engineering

Bone Tissue Engineering Book
Author : Jeffrey O. Hollinger,Thomas A. Einhorn,Bruce Doll,Charles Sfeir
Publisher : CRC Press
Release : 2004-10-14
ISBN : 1135501912
Language : En, Es, Fr & De

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Book Description :

Focusing on bone biology, Bone Tissue Engineering integrates basic sciences with tissue engineering. It includes contributions from world-renowned researchers and clinicians who discuss key topics such as different models and approaches to bone tissue engineering, as well as exciting clinical applications for patients. Divided into four sections, t

Materials and Devices for Bone Disorders

Materials and Devices for Bone Disorders Book
Author : Susmita Bose,Amit Bandyopadhyay
Publisher : Academic Press
Release : 2016-11-03
ISBN : 0128028033
Language : En, Es, Fr & De

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Book Description :

Materials for Bone Disorders is written by a cross-disciplinary team of research scientists, engineers, and clinicians and bridges the gap between materials science and bone disorders, providing integrated coverage of biomaterials and their applications. The bioceramics, biopolymers, composites, and metallic materials used in the treatment of bone disorders are introduced, as are their interactions with cells, biomolecules, and body tissues. The main types of bone disorder and disease are covered including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders. Bone disorders are common across all ages. Various forms of bone disorders can change the lifestyle of otherwise normal and healthy people. With the development of novel materials, many forms of bone disorders are becoming manageable, allowing people to lead a fairly normal life. Specific consideration is given to areas where recent advances are enabling new treatments, such as the use of resorbable ceramics in bone tissue engineering and drug delivery, newer polymer-based implants in load-bearing contexts, and engineering biomaterials surfaces including modifying surface chemistry. Ethical and regulatory issues are also explored. Explores biomaterials for bone repair and related applications in orthopedics and dentistry in a clinical context Introduces biomaterials applications in the context of specific diseases, bone disorders, and theraputic contexts Includes input from a world-class team of research scientists, engineers, and clinicians Covers the main types of bone disorder and disease including osteoporosis, spinal injury, load bearing joint diseases, bone cancer, and forms of cranio-maxillofacial disorders

Functional Nanomaterials for Regenerative Tissue Medicines

Functional Nanomaterials for Regenerative Tissue Medicines Book
Author : Mariappan Rajan
Publisher : CRC Press
Release : 2021-12-09
ISBN : 100048694X
Language : En, Es, Fr & De

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Book Description :

This book covers nanomaterials in tissue engineering for regenerative therapies of heart, skin, eye, skeletal muscle, and the nervous system. The book emphasizes fundamental design concepts and emerging forms of nanomaterials in soft- and hard-tissue engineering. FEATURES Fills a gap in the literature related to the application of nanomaterials in hard- and soft-tissue regeneration, repair, and restructure Discusses a variety of applications, including cardiac, kidney, liver, bone, wound healing, artificial organs, and dental Presents advantages and limitations of various nanomaterials alongside future challenges Functional Nanomaterials for Regenerative Tissue Medicines is essential for academics and industry professionals working in tissue engineering, biomedicine, biopharmaceuticals, and nanotechnology. It is primarily intended for materials researchers (to develop the platforms related to tissue regeneration) as well as clinicians (to learn and apply nanomaterials in their practice) and industrial scientists (to develop commercial blood substitute products).

Octacalcium Phosphate Biomaterials

Octacalcium Phosphate Biomaterials Book
Author : Gerard Insley,Osamu Suzuki
Publisher : Woodhead Publishing
Release : 2019-11-20
ISBN : 0081025122
Language : En, Es, Fr & De

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Book Description :

Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material. Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties Presents the clinical potential of octacalcium phosphate biomaterials Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair Book
Author : Mario Barbosa,M Cristina L Martins
Publisher : Woodhead Publishing
Release : 2017-09-25
ISBN : 008100852X
Language : En, Es, Fr & De

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Book Description :

Peptides and Proteins as Biomaterials for Tissue Regeneration and Repair highlights the various important considerations that go into biomaterial development, both in terms of fundamentals and applications. After covering a general introduction to protein and cell interactions with biomaterials, the book discusses proteins in biomaterials that mimic the extracellular matrix (ECM). The properties, fabrication and application of peptide biomaterials and protein-based biomaterials are discussed in addition to in vivo and in vitro studies. This book is a valuable resource for researchers, scientists and advanced students interested in biomaterials science, chemistry, molecular biology and nanotechnology. Presents an all-inclusive and authoritative coverage of the important role which protein and peptides play as biomaterials for tissue regeneration Explores protein and peptides from the fundamentals, to processing and applications Written by an international group of leading biomaterials researchers

Smart Biomaterials

Smart Biomaterials Book
Author : Mitsuhiro Ebara,Yohei Kotsuchibashi,Ravin Narain,Naokazu Idota,Young-Jin Kim,John M. Hoffman,Koichiro Uto,Takao Aoyagi
Publisher : Springer
Release : 2014-05-28
ISBN : 4431544003
Language : En, Es, Fr & De

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Book Description :

This book provides comprehensive coverage of smart biomaterials and their potential applications, a field that is developing at a very rapid pace. Because smart biomaterials are an emerging class of biomaterials that respond to small changes in external stimuli with large discontinuous changes in their physical properties, they have been designed to act as an “on–off” switch for, among others, bio separation, immunoanalysis, drug delivery technologies, gene therapy, diagnostics, bio sensors and artificial muscles. After an introduction to the topic and the history of smart biomaterials, the author gives the reader an in-depth look at the properties, mechanics, and characterization of smart biomaterials including hydrogels, particles, assemblies, surfaces, fibers and conjugates. Information on the wide range of applications for these materials follows, including drug delivery, tissue engineering, diagnostics, biosensors, bio separation and actuators. In addition, recent advances in shape memory biomaterials as active components of medical devices are also presented.

Advanced Techniques in Bone Regeneration

Advanced Techniques in Bone Regeneration Book
Author : Alessandro Rozim Zorzi,João Batista de Miranda
Publisher : BoD – Books on Demand
Release : 2016-08-31
ISBN : 9535125389
Language : En, Es, Fr & De

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Book Description :

Advanced Techniques in Bone Regeneration is a book that brings together over 15 chapters, written by leading practitioners and researchers, of the latest advances in the area, including surgical techniques, new discoveries, and promising methods involving biomaterials and tissue engineering. This book is intended for all who work in the treatment of disorders involving problems with the regeneration of bone tissue, are doctors or dentists, as well as are researchers and teachers involved in this exciting field of scientific knowledge.

Mineralized Collagen Bone Graft Substitutes

Mineralized Collagen Bone Graft Substitutes Book
Author : Xiu-Mei Wang,Zhi-Ye Qiu,Helen Cui
Publisher : Woodhead Publishing
Release : 2019-04-18
ISBN : 0081027397
Language : En, Es, Fr & De

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Book Description :

Mineralized Collagen Bone Graft Substitutes presents a comprehensive study of biomimetic mineralized collagen, synthesized in vitro, a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the clinical use of this novel material, the book provides a complete examination, from bench to bedside. Chapters discuss natural bone and familiar biomaterials for bone repair, the preparation and safety of mineralized collagen, products made of mineralized collagen, and present clinical case studies. This book is an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. Provides a deep analysis of synthetic collagen, from bench to bedside Systematically examines the structure, principles, properties, biomimetic synthesis and characterization of mineralized collagen for bone repair Includes case studies that look at a range of clinical bone repair applications of Mineralized collagen and their clinical results

Translating Biomaterials for Bone Graft

Translating Biomaterials for Bone Graft Book
Author : Joo L. Ong,Teja Guda
Publisher : CRC Press
Release : 2017-01-06
ISBN : 1315363518
Language : En, Es, Fr & De

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Book Description :

Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

Biomedical Applications of Inorganic Materials

Biomedical Applications of Inorganic Materials Book
Author : Gareth R Williams
Publisher : Royal Society of Chemistry
Release : 2021-12-20
ISBN : 178801930X
Language : En, Es, Fr & De

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Book Description :

This book provides a contemporary research-led overview of the applications of inorganic materials in biomedicine. It begins with a short introduction summarising key concepts in inorganic materials (layered materials, framework materials etc.), and explaining the need for new materials in medicine. It then discusses the key areas in which inorganic materials have been applied, considering: drug delivery; imaging; diagnostics and theranostics; hard matter restoration; and vaccines. Each chapter gives an overview of the major extant challenges in the research area, before presenting a systematic review of how inorganic materials have been applied to gain traction in the field. A clear focus is maintained on the fate of the applied materials in vivo, clinical considerations, and the path to translation from lab to clinic. With contributions from leading researchers, Biomedical Applications of Inorganic Materials will provide a comprehensive introduction for advanced undergraduates, postgraduates and researchers wishing to learn about the topic.

Biomaterials for Bone Regeneration

Biomaterials for Bone Regeneration Book
Author : P. Dubruel,S. Van Vlierberghe
Publisher : Elsevier
Release : 2014-06-09
ISBN : 0857098101
Language : En, Es, Fr & De

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Book Description :

Novel Biomaterials for Bone Regeneration provides a comprehensive review of currently available biomaterials and how they can be applied in bone regeneration. In recent decades, there has been a shift from the idea of using biomaterials as passive substitutes for damaged bones towards the concept of biomaterials as aids for the regeneration of a host's own bone tissue. This has generated an important field of research and a range of technological developments. Part one of this book discusses a wide range of materials, including calcium phosphate cements, hydrogels, biopolymers, synthetic polymers, and shape memory polymers. Part two then turns to the processing and surface modification of biomaterials, as well as how biomaterials can be evaluated both for their mechanical properties and for immunocompatibility with the host. Finally, part three covers a variety of cellular approaches, and production and delivery of biomaterials for bone regeneration. Chapters also consider the potential of electromagnetic and ultrasonic stimulation of biomaterials to aid in the regenerative process. Novel Biomaterials for Bone Regeneration represents an important resource for academics, clinicians, and industry professionals working in the area of biomedical materials, providing them with both an overview of the current state-of-the-art, and an indication of potential future developments. Provides comprehensive coverage of novel materials, techniques, and applications of biomaterials for bone regeneration Provides vital information on the various types of materials used in bone regeneration Discusses processing, modification, and evaluation techniques of biomaterials, and looks at cellular approaches and stimulation of biomaterials for bone regeneration

Tissue Engineering Using Ceramics and Polymers

Tissue Engineering Using Ceramics and Polymers Book
Author : Aldo R. Boccaccini,J Gough
Publisher : Elsevier
Release : 2007-10-31
ISBN : 1845693817
Language : En, Es, Fr & De

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Book Description :

Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering. An innovative and up-to-date reference for professionals and academics Environmental scanning electron microscopy is discussed Analyses bone regeneration and specific types of tisue engineering

Biomechanics and Biomaterials in Orthopedics

Biomechanics and Biomaterials in Orthopedics Book
Author : Dominique G. Poitout
Publisher : Springer
Release : 2016-06-15
ISBN : 1848826648
Language : En, Es, Fr & De

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Book Description :

With the constant evolution of implant technology, and improvement in the production of allograft and bone substitutes, the armamentarium of the orthopaedic surgeon has significantly expanded. In particular, the recent involvement of nanotechnologies opens up the possibilities of new approaches in the interactive interfaces of implants. With many important developments occurring since the first edition of this well-received book, this updated resource informs orthopaedic practitioners on a wide range of biomechanical advances in one complete reference guide. Biomechanics and Biomaterials in Orthopedics, 2nd edition compiles the most prominent work in the discipline to offer newly-qualified orthopedic surgeons a summary of the fundamental skills that they will need to apply in their day-to-day work, while also updating the knowledge of experienced surgeons. This book covers both basic concepts concerning biomaterials and biomechanics as well as their clinical application and the experience from everyday practical use. This book will be of great value to specialists in orthopedics and traumatology, while also providing an important basis for graduate and postgraduate learning.

The Chemistry of Inorganic Biomaterials

The Chemistry of Inorganic Biomaterials Book
Author : Christopher Spicer
Publisher : Royal Society of Chemistry
Release : 2021-08-18
ISBN : 1788017536
Language : En, Es, Fr & De

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Book Description :

This book overviews the underlying chemistry behind the most common and cutting-edge inorganic materials in current use, or approaching use, in vivo.

Advances in Calcium Phosphate Biomaterials

Advances in Calcium Phosphate Biomaterials Book
Author : Besim Ben-Nissan
Publisher : Springer Science & Business
Release : 2014-04-17
ISBN : 3642539807
Language : En, Es, Fr & De

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Book Description :

Advances in Calcium Phosphate Biomaterials presents a comprehensive, state-of-the-art review of the latest advances in developing calcium phosphate biomaterials and their applications in medicine. It covers the fundamental structures, synthesis methods, characterization methods, and the physical and chemical properties of calcium phosphate biomaterials, as well as the synthesis and properties of calcium phosphate-based biomaterials in regenerative medicine and their clinical applications. The book brings together these new concepts, mechanisms and methods in contributions by both young and “veteran” academics, clinicians, and researchers to forward the knowledge and expertise on calcium phosphate and related materials. Accordingly, the book not only covers the fundamentals but also open new avenues for meeting future challenges in research and clinical applications. Besim Ben-Nissan is a Professor of Chemistry and Forensic Science at the University of Technology, Sydney, Australia