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Biotin And Other Interferences In Immunoassays

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Biotin and Other Interferences in Immunoassays

Biotin and Other Interferences in Immunoassays Book
Author : Amitava Dasgupta
Publisher : Elsevier
Release : 2019-01-15
ISBN : 0128167416
Language : En, Es, Fr & De

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Book Description :

Biotin and Other Interferences in Immunoassays: A Concise Guide is aimed at clinical laboratory scientists, medical technologists and pathologists who are often the first individuals contacted by a clinician when a laboratory test result does not correlate with clinical presentation. Research scientists working in diagnostics companies will also find this information essential. Sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratory are also discussed so readers can get all important information from one concise guide. This succinct, user-friendly reference provides the necessary information to address high levels of biotin in clinical laboratory results. Discusses issues of biotin interferences and ways to avoid them for accurate clinical laboratory results Provides sources of errors in non-immunoassay based methods used in clinical chemistry and toxicology laboratories Highlights how to handle specimens in the lab and how to eliminate the effect of biotin in precious samples

Clinical Chemistry Immunology and Laboratory Quality Control

Clinical Chemistry  Immunology and Laboratory Quality Control Book
Author : Amitava Dasgupta,Amer Wahed
Publisher : Elsevier
Release : 2021-07-01
ISBN : 0128159618
Language : En, Es, Fr & De

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Book Description :

Clinical Chemistry, Immunology and Laboratory Quality Control: A Comprehensive Review for Board Preparation, Certification and Clinical Practice, Second Edition presents core topics and 70 case studies that illustrate the application of clinical chemistry knowledge to everyday patient care. This succinct reference offers practical examples of how things function in the pathology clinic with useful lists, key points, case studies and a bullet point format ideal for quick pre-board review. While larger textbooks in clinical chemistry provide highly detailed information regarding instrumentation and statistics, this book is designed to educate senior medical students, residents and fellows on how tests are performed. This second edition successfully helps pathology residents gain command of clinical chemistry, toxicology, immunology, and laboratory statistics in an effort to help them prepare for the American Board of Pathology examination. Clinical chemistry is a topic in which many senior medical students and pathology residents face challenges. Includes chapters on drug-herb interaction and pharmacogenomics, topics not covered by textbooks in the field of clinical chemistry or laboratory medicine Presents seventy case studies that highlight clinical relevance and errors to avoid Covers important clinical information found in larger textbooks in a more succinct and easy-to-understand manner

Detection Methods in Precision Medicine

Detection Methods in Precision Medicine Book
Author : Mengsu (Michael) Yang,Michael Thompson
Publisher : Royal Society of Chemistry
Release : 2020-12-10
ISBN : 1788019962
Language : En, Es, Fr & De

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Book Description :

Precision medicine is a topical subject that attracts tremendous attention from scientific and medical communities, being set to transform health care in the future. This book will be among the first to cover the detection methods for precision medicine. The first section provides an overview of the biomarkers used for precision medicine, such as proteins, nucleic acids, and metabolites. The coverage then turns to sequencing techniques and their applications, and other bioanalytical techniques, including mass spectrometry for proteome and phosphoproteome analysis, immunological methods and droplet technologies. The final sections include biosensors applied to precision medicine and clinical applications. This book provides a reference for researchers and students interested and working in the development of bioanalytical techniques for clinical applications. It provides a useful introduction for physicians and medical laboratory technologists to the recent advances in detection methods for precision medicine.

Handbook of Diagnostic Endocrinology

Handbook of Diagnostic Endocrinology Book
Author : William E. Winter,Lori J. Sokoll,Brett Holmquist,Roger L. Bertholf
Publisher : Academic Press
Release : 2020-10-06
ISBN : 0128182784
Language : En, Es, Fr & De

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Book Description :

The clinical laboratory plays a critical role in the diagnosis and management of endocrine and related metabolic disorders, which are leading causes of morbidity and mortality in children and adults. The Handbook of Diagnostic Endocrinology, Third Edition, provides a ready reference for the evaluation, diagnosis, and monitoring of such disorders. This revision incorporates translational medicine, connecting what clinicians need to know with those in research providing a clinical context to which they can relate their molecular findings. This book solves the needs of clinicians and researchers by bringing together in one book endocrinology at the molecular and clinical levels. As the intricacies of intracellular signaling have become better understood, states of hormone resistance are now increasingly recognized. The most common endocrinopathy in westernized countries, the metabolic syndrome, results, to a large extent, from insulin resistance. The complexity of the circulating forms of various hormones are acknowledged in this revision. Each chapter focuses on the biochemical tests that are required, either in the basal state or following provocation or suppression, to assist in the diagnosis of the various disorders Describes proper sample collection and relevant interpretations of laboratory tests Contains essential molecular biology and incorporates it with the clinical information Includes the discovery of new diagnostic and treatment methods

Accurate Results in the Clinical Laboratory

Accurate Results in the Clinical Laboratory Book
Author : Amitava Dasgupta,Jorge L. Sepulveda
Publisher : Elsevier
Release : 2019-07-20
ISBN : 0128137770
Language : En, Es, Fr & De

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Book Description :

Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, Second Edition, provides a comprehensive review of the factors leading to errors in all areas of clinical laboratory testing. This trusted guide addresses interference issues in all laboratory tests, including patient epigenetics, processes of specimen collection, enzymes and biomarkers. Clinicians and laboratory scientists will both benefit from this reference that applies discussions to both accurate specimen analysis and optimal patient care. Hence, this is the perfect reference for clinical laboratorians, from trainees, to experienced pathologists and directors. Provides comprehensive coverage across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing Includes new case studies that highlight clinical relevance and errors to avoid Highlights the best titles published within a variety of medical specialties Reviewed by medical librarians and content specialists, with key selections compiled in their annual list

Management of Patients with Pseudo Endocrine Disorders

Management of Patients with Pseudo Endocrine Disorders Book
Author : Michael T. McDermott
Publisher : Springer Nature
Release : 2019-09-26
ISBN : 3030227200
Language : En, Es, Fr & De

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Book Description :

Comprised of illustrative clinical cases, this unique pocket guide presents descriptions of patients who have symptoms, physical signs or laboratory abnormalities that they believe are due to disorders of the endocrine system (hormone secreting glands and overall metabolism) but which are not, or probably are not, due to an endocrine disorder. These are common situations in the clinical practice of endocrinology. Each chapter includes clinical cases illustrating differing presentations and outcomes, and each individual case description is followed by a discussion that includes the differential diagnosis of these symptoms, signs and/or lab abnormalities and why they are not likely due to endocrine disease or, alternatively, why and how a deeper exploration for endocrine disorders might be needed. In all cases, an emphasis is placed on listening to the patient and providing a respectful and compassionate response and approach to evaluation and management of the proposed disorder. Discussions are referenced whenever reference material is available, and evidence-based clinical practice guidelines are presented whenever applicable. Topics discussed include chronic and adrenal fatigue, obesity, anxiety and depression, sweating and flushing, alcohol- and opioid-induced symptoms, low testosterone, pseudo-hypoglycemia and pseudo-Cushing's syndrome, among others. Clinical endocrinologists, primary care physicians and related allied medical professionals will find Management of Patients with Pseudo-Endocrine Disorders a valuable resource in their clinical practice with these common but often challenging patients.

Handbook of Immunoassay Technologies

Handbook of Immunoassay Technologies Book
Author : Sandeep K. Vashist,John H.T. Luong
Publisher : Academic Press
Release : 2018-01-02
ISBN : 012811794X
Language : En, Es, Fr & De

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Book Description :

Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules. Provides a valuable increase of understanding of cellular and biomedical functions Gives the most updated resource in the field of immunoassays, providing the comprehensive details of various types of immunoassays that need to be performed in healthcare, and in industrial, environmental and other biochemical settings Discusses all multifarious aspects of immunoassays Describes the immunoassay formats, along with their principle of operation, characteristics, pros and cons, and potential biochemical and bioanalytical applications Provides extensive knowledge and guided insights as detailed by experienced, renowned experts and key opinion makers in the field of immunoassays

Immunoassay

Immunoassay Book
Author : Eleftherios P. Diamandis,Theodore K. Christopoulos
Publisher : San Diego ; Toronto : Academic Press
Release : 1996-01
ISBN : 9780122147302
Language : En, Es, Fr & De

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Book Description :

Immunoassays are among the most powerful and sensitive technologies now available for patient diagnosis and monitoring. This book is a guide to information on the theory and practice of immunoassays. It discusses the scientific basis of these technologies and provides protocols for specific assays. Contents - Past, Present, And Future of Immunological Assays. Immune Function and Antibody Structure. Theory of Immunoassays. Data Interpretation and Quality Control. Production and Purification of Antibodies. Antibody Engineering. Interferences in Immunoassays. Labeling of Antibodies and Antigens. Solid-Phases in Immunoassay. Immunoassay Configurations. The Avidin-Biotin System. Radioimmunoassay. Enzyme Immunoassay. Fluorescence Immunoassays. Chemiluminescence Immunoassay. Bioluminescence Immunoassays. Nephelometric and Turbidimetric Immunoassay. Simultaneous Multianalyte Immunoassays. Noncompetitive Immunoassay for Small Molecules. Free Hormone Measurements. Automation of Immunological Assays. Thin Film Immunoassays. Immunoblotting Techniques. Development of In-House Immunological Assays.

Present Knowledge in Nutrition

Present Knowledge in Nutrition Book
Author : Bernadette P. Marriott,Diane F. Birt,Virginia A. Stalling,Allison A. Yates
Publisher : Academic Press
Release : 2020-07-21
ISBN : 0128198427
Language : En, Es, Fr & De

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Book Description :

Present Knowledge in Nutrition: Basic Nutrition and Metabolism, Eleventh Edition, provides an accessible, referenced source on the most current information in the broad field of nutrition. Now broken into two volumes and updated to reflect scientific advancements since the publication of the last edition, the book includes expanded coverage on basic nutrition, metabolism and clinical and applied topics. This volume provides coverage of macronutrients, vitamins, minerals and other dietary components and concludes with new approaches in nutrition science that apply to many, if not all, of the nutrients and dietary components presented throughout the reference. Advanced undergraduate, graduate and postgraduate students in nutrition, public health, medicine and related fields will find this resource useful. In addition, professionals in academia and medicine, including clinicians, dietitians, physicians, health professionals, academics and industrial and government researchers will find the content extremely useful. The book was produced in cooperation with the International Life Sciences Institute (https://ilsi.org/). Provides an accessible source of the most current, reliable and comprehensive information in the broad field of nutrition Features new chapters on topics of emerging importance, including the microbiome, eating disorders, nutrition in extreme environments, and the role of nutrition and cognition in mental status Covers topics of clinical relevance, including the role of nutrition in cancer support, ICU nutrition, supporting patients with burns, and wasting, deconditioning and hypermetabolic conditions

Practical Management of Thyroid Cancer

Practical Management of Thyroid Cancer Book
Author : Ujjal K. Mallick,Clive Harmer
Publisher : Springer
Release : 2018-09-17
ISBN : 3319917250
Language : En, Es, Fr & De

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Book Description :

Written by a multidisciplinary team of experts involved in the development of standards and guidelines for its management in the USA, UK, Europe and Asia, the book contains succinct and knowledgeable summaries of the management of thyroid cancer. Every chapter describes a different aspect of care, and provides clear and detailed information about caring for patients with this group of tumors. This is an invaluable reference to health care professionals, from primary to tertiary care, involved in the management of thyroid cancer such as clinical nurse specialists, clinical psychologists, family medicine practitioners, specialists in palliative care (especially for anaplastic thyroid cancers), geneticists and surgeons, endocrinologists, oncologists, pathologists, and radiologists.

71st AACC Annual Scientific Meeting Clinical Lab Expo

71st AACC Annual Scientific Meeting   Clinical Lab Expo Book
Author : American Association for Clinical Chemistry (AACC)
Publisher : CTI Meeting Technology
Release : 2019-07-11
ISBN : 0463748670
Language : En, Es, Fr & De

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Book Description :

The poster abstracts accepted for the 71st AACC Annual Scientific Meeting & Clinical Lab Expo. AACC is a global scientific and medical professional organization dedicated to clinical laboratory science and its application to healthcare. Our leadership in education, advocacy and collaboration helps lab professionals adapt to change and do what they do best: provide vital insight and guidance so patients get the care they need.

Clinical Immunology Serology

Clinical Immunology   Serology Book
Author : Linda E Miller,Christine Dorresteyn Stevens
Publisher : F.A. Davis
Release : 2021-02-08
ISBN : 1719645965
Language : En, Es, Fr & De

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Book Description :

Here’s the practical introduction you need to understand the essential theoretical principles of clinical immunology and the serological and molecular techniques commonly used in the laboratory. You’ll begin with an introduction to the immune system; then explore basic immunologic procedures; examine immune disorders; and study the serological and molecular diagnosis of infectious disease. An easy-to-read, student-friendly approach emphasizes the direct application of theory to clinical laboratory practice. Each chapter is a complete learning module with learning outcomes, chapter outlines, theoretical principles, illustrations, and definitions of relevant terminology. Review questions and case studies help you assess your mastery of the material. A glossary at the end of the book puts must-know information at your fingertips.

The Immunoassay Handbook

The Immunoassay Handbook Book
Author : David Wild
Publisher : Elsevier
Release : 2005-07-04
ISBN : 9780080445267
Language : En, Es, Fr & De

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Book Description :

Containing updated and new information on advanced technology - including micro and nanoscale immunoassays - this text provides a mix of practical information coupled with a review of clincal applications and practical examples.

70th AACC Annual Scientific Meeting

70th AACC Annual Scientific Meeting Book
Author : American Association for Clinical Chemistry
Publisher : Coe Truman International, LLC
Release : 2018-07-11
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download 70th AACC Annual Scientific Meeting book written by American Association for Clinical Chemistry, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

68th AACC Annual Scientific Meeting Abstract eBook

68th AACC Annual Scientific Meeting Abstract eBook Book
Author : American Association for Clinical Chemistry
Publisher : CTI Meeting Technology
Release : 2016-06-14
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The poster abstracts presented at the 68th AACC Annual Scientific Meeting & Clinical Lab Expo and published in Clinical Chemistry, Vol. 62, No. 10, Supplement, 2016.

Thyroid and Parathyroid Disorders in Children

Thyroid and Parathyroid Disorders in Children Book
Author : Pallavi Iyer,Herbert Chen
Publisher : CRC Press
Release : 2020-11-17
ISBN : 1000216985
Language : En, Es, Fr & De

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Book Description :

Thyroid and Parathyroid Disorders in Children: A Practical Handbook offers a focused and practical approach to diagnostic and therapeutic (both medical and surgical) interventions in management of thyroid and parathyroid diseases in children. It is divided into two sections: thyroid and parathyroid, with each section discussing the use of the laboratory testing and radiographic modalities in the study of these glands. This guides the reader to know the utility and limitations of the findings when approaching a child with these conditions. Written by international experts in the fields of pediatric endocrinology and endocrine surgery, it is ideal for trainees, practicing physicians and professionals who care for children with endocrine conditions. Key Features Discusses differences in recognition and management of thyroid and parathyroid disorders in children compared with adults, with both common and rare disorders described along with their medical and surgical treatment techniques. Aids the practicing physicians, endocrinologists, trainees, and fellows in understanding the complex concepts in a practical way. Fills the gap in the market for a much-needed book concentrated on endocrine neck diseases of childhood.

Hair and Scalp Treatments

Hair and Scalp Treatments Book
Author : Antonella Tosti,Daniel Asz-Sigall,Rodrigo Pirmez
Publisher : Springer Nature
Release : 2019-09-12
ISBN : 3030215555
Language : En, Es, Fr & De

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Book Description :

Conditions of the hair and scalp often cause significant psychological distress and sometimes physical discomfort for patients. Similarly, finding the right treatment can prove challenging for the physician. Hair and Scalp Treatments -- A Practical Guide, focuses on therapy with each chapter briefly describing the disease to the reader and then teaching the step-by-step therapeutic algorithm. Procedures commonly used in the treatment of alopecias are also reviewed and detailed in specific chapters. This book also discusses everyday questions that patients commonly ask doctors and provides practical tips such as how to recommend the best shampoo, conditioner or hair dye for your patient, or how to prescribe the right nutritional supplements. There are additional sections on future treatments on the horizon and how regenerative medicine can be used. Hair and Scalp Treatments -- A Practical Guide, is the only book of its kind focused on treatment and addresses topics that are not covered by current titles on hair disorders. Written and edited by leading experts in the field, this practical guide can be used not only by dermatologists but by general practice and family physicians as well.

Biochemical and Imaging Diagnostics in Endocrinology An Issue of Endocrinology and Metabolism Clinics of North America

Biochemical and Imaging Diagnostics in Endocrinology  An Issue of Endocrinology and Metabolism Clinics of North America Book
Author : Richard J. Auchus,Barry D. Pressman,Adina F. Turcu,Alan D. Waxman
Publisher : Elsevier Health Sciences
Release : 2017-08-17
ISBN : 0323545513
Language : En, Es, Fr & De

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Book Description :

This issue of Endocrinology and Metabolism Clinics, guest edited by Drs. Richard Auchus, Adina Turcu, Alan D. Waxman, and Barry D. Pressman, is devoted to Biochemical and Imaging Diagnostics in Endocrinology. Articles in this issue include Mass spectrometry applicability in endocrine testing; Point-of-care endocrine testing; Thyroid, Bone; NET; Predictors of fertility; Thyroid ultrasound imaging and needle biopsy; Pituitary imaging; Adrenal imaging; Pancreatic imaging; Diagnosis and management of thyroid disorders; Neuroendocrine Tumors, and Parathyroid Imaging.

ELISA and Other Solid Phase Immunoassays

ELISA and Other Solid Phase Immunoassays Book
Author : D. M. Kemeny,S. J. Challacombe
Publisher : John Wiley & Sons
Release : 1991-01-08
ISBN : 9780471909828
Language : En, Es, Fr & De

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Book Description :

This is a quick-reference manual on practical aspects of immunoassay. Providing a theoretical and practical basis for modern applications of solid-phase immunoassays, this text brings together experts who have used ELISA and other assays in a variety of fields. Contributors offer step-by-step guidance on how to use the various techniques involved in immunoassay. These techniques are extemely useful to laboratory-based researchers and technicians working on the detection of allergy, the AIDS virus, autoimmunity, etc. Chapters analyze the solid-phase supports used, the amplification systems, and the quantitation and affinity of antibodies and discuss the applications of assays to biology, immunology, and microbiology.

Advanced Concepts in Fluorescence Sensing

Advanced Concepts in Fluorescence Sensing Book
Author : Chris D. Geddes,Joseph R. Lakowicz
Publisher : Springer Science & Business Media
Release : 2010-07-18
ISBN : 9780387236476
Language : En, Es, Fr & De

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Book Description :

Over the last decade, fluorescence has become the dominant tool in biotechnology and medical imaging. These exciting advances have been underpinned by the advances in time-resolved techniques and instrumentation, probe design, chemical / biochemical sensing, coupled with our furthered knowledge in biology. Complementary volumes 9 & 10, Advanced Concepts of Fluorescence Sensing: Small Molecule Sensing and Advanced Concepts of Fluorescence Sensing: Macromolecular Sensing, aim to summarize the current state of the art in fluorescent sensing. For this reason, Drs. Geddes and Lakowicz have invited chapters, encompassing a broad range of fluorescence sensing techniques. Some chapters deal with small molecule sensors, such as for anions, cations, and CO2, while others summarize recent advances in protein-based and macromolecular sensors. The Editors have, however, not included DNA or RNA based sensing in this volume, as this were reviewed in Volume 7 and is to be the subject of a more detailed volume in the near future.