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Biopolymer Science For Proteins And Peptides

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Biopolymer Science for Proteins and Peptides

Biopolymer Science for Proteins and Peptides Book
Author : Keiji Numata
Publisher : Elsevier
Release : 2021-08-27
ISBN : 0128205563
Language : En, Es, Fr & De

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Book Description :

Biopolymer Science for Proteins and Peptides introduces all aspects of natural polymers based on structural proteins and peptides, presenting synthesis, structure, properties, proteins, materials design, and applications. The book begins by presenting the core concepts of polypeptide and protein materials, before discussing synthesis and structure in detail. The next part of the book describes physical properties, biological properties, and issues surrounding stability. Subsequent chapters offer in-depth coverage of both natural and structural protein sources, including collagen, silk, elastin, resilin, keratin, foot protein, and reflectin, and the materials that can be designed from them, such as films, fibers, textiles, microparticles, sponges and scaffolds, nanomaterials, blends, and composites. These materials are also analyzed against the available synthetic polymers. Finally, the text explores current applications and potential future developments. This is an essential resource for researchers and advanced students across a range of disciplines, including biopolymers, structural proteins, polymer science, materials science, biomaterials, biology, biotechnology, chemistry, engineering, and pharmaceutical science. In an industry setting, this is of great interest to scientists and R&D professionals working in industries with an interest in bio-based polymers for advanced applications. Explains how biopolymers from structural proteins and peptides can be developed into materials, such as films, fibers, textiles, microparticles, sponges and scaffolds, nanomaterials, blends, and polymer composites Provides the reader a solid understanding of the structure, synthesis, and properties Guides the reader from sources, including collagen, silk, elastin, resilin, keratin, and reflectin, to material design and cutting-edge applications

Designer Biopolymers

Designer Biopolymers Book
Author : Ayae Sugawara-Narutaki ,Yukiko Kamiya
Publisher : MDPI
Release : 2020-12-14
ISBN : 3039363700
Language : En, Es, Fr & De

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Book Description :

Nature has evolved sequence-controlled polymers, such as DNA and proteins, over its long history. The recent progress of synthetic chemistry, DNA recombinant technology, and computational science, as well as the elucidation of molecular mechanisms in biological processes, drive us to design ingenious polymers that are inspired by naturally occurring polymers, but surpass them in specialized functions. The term “designer biopolymers” refers to polymers which consist of biological building units, such as nucleotides, amino acids, and monosaccharides, in a sequence-controlled manner. This book particularly focuses on the self-assembling aspect of designer biopolymers. Self-assembly is one common feature in biopolymers that is used to realize their dynamic biological activities and is strictly controlled by the sequence of biopolymers. In a broad sense, the self-assembly of biopolymers includes a double-helix formation of DNA, protein folding, and higher-order protein assembly (e.g., viral capsids). Designer biopolymers are now going beyond what nature evolved: researchers have generated DNA origami, protein cages, peptide nanofibers, and gels. This book illustrates the latest interdisciplinary work on self-assembling designer biopolymers. As shown by this book, the self-assembly of biopolymers has a great impact on a variety of research fields, including molecular biology, neurodegenerative diseases, drug delivery, gene therapy, regenerative medicine, and biomineralization. Designer biopolymers will help researchers to better understand biological processes, as well as to create innovative molecular systems. We believe that this book will provide readers with new ideas for their molecular design strategies for frontier research.

Advances in Protein and Peptide Sciences

Advances in Protein and Peptide Sciences Book
Author : Ben M. Dunn
Publisher : Bentham Science Publishers
Release : 2013-10-30
ISBN : 160805487X
Language : En, Es, Fr & De

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Book Description :

Advances in Protein and Peptide Sciences is a book series focused on leading-edge research on the structure, physical properties, and functions of proteins and peptides. The series presents highly cited contributions first published in the journal Current Protein and Peptide Science. Authors of these contributions have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in the field of protein and peptide chemistry and molecular biology, including membrane proteins and their interactions with ligands, computational methods, and proteins in disease and biotechnology.

Modern Biopolymer Science

Modern Biopolymer Science Book
Author : Stefan Kasapis,Ian T. Norton,Johan B, Ubbink
Publisher : Academic Press
Release : 2009-07-21
ISBN : 9780080921143
Language : En, Es, Fr & De

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Book Description :

Industrialists developing new food and pharmaceutical products face the challenge of innovation in an increasingly competitive market that must consider incredient cost, product added-value, expectations of a healthy life-style, improved sensory impact, controlled delivery of active compounds and last, but not lease, product stability. While much work has been done to explore, understand, and address these issues, a gap has emerged between recent advances in fundamental knowledge and its direct application to product situations with a growing need for scientific input. Modern Biopolymer Science matches science to application by first acknowledging the differing viewpoints between those working with low-solids and those working with high-solids, and then sharing the expertise of those two camps under a unified framework of materials science. * Real-world utilisation of fundamental science to achieve breakthroughs in product development * Includes a wide range of related aspects of low and high-solids systems for foods and pharmaceuticals * Covers more than bio-olymer science in foods by including biopolymer interactions with bioactive compounds, issues of importance in drug delivery and medicinal chemistry

Science and Technology Against Microbial Pathogens

Science and Technology Against Microbial Pathogens Book
Author : A. Méndez-Vilas
Publisher : World Scientific
Release : 2011
ISBN : 9814354856
Language : En, Es, Fr & De

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Book Description :

The aim of this book is to disseminate the most recent research in science and technology against microbial pathogens presented at the first edition of the ICAR Conference Series (ICAR2010) held in Valladolid, Spain, in November 2010. This volume is a compilation of 86 chapters written by active researchers that offer information and experiences and afford critical insights into anti-microbe strategies in a general context marked by the threat posed by the increasing antimicrobial resistance of pathogenic microorganisms. "Anti" is here taken in a wide sense as "against cell cycle, adhesion, or communication," and when harmful for the human health (infectious diseases, chemotherapy etc.) and industry or economy (food, agriculture, water systems etc.) The book examines this interesting subject area from antimicrobial resistance (superbugs, emerging and re-emerging pathogens etc.), to the use of natural products or microbes against microbial pathogens, not forgetting antimicrobial chemistry, physics and material science. Readers will find in a single volume, up-to-date information of the current knowledge in antimicrobial research. The book is recommended for researchers from a broad range of academic disciplines that are contributing in the battle against harmful microorganisms, not only those more traditionally involved in this research area (microbiologists, biochemists, geneticists, clinicians etc.), but also experimental and theoretical/computational chemists, physicists or engineers.

Antimicrobial Peptides

Antimicrobial Peptides Book
Author : Guangshun Wang
Publisher : CABI
Release : 2010
ISBN : 1845936949
Language : En, Es, Fr & De

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Book Description :

The purpose of this book is to provide a comprehensive account on current antimicrobial peptide research in two major directions. The first direction delineates the classic path for peptide development, ranging through identification, design, structure and mode of action studies. The second direction describes novel strategies for developing peptide therapeutics based on our knowledge of host defence antimicrobial peptides discovered in living organisms. Part I provides an overview of nomenclature, classification and bioinformatic analysis of antimicrobial peptides from bacteria, plants and animals. Subsequently, lantibiotics from bacteria and cyclotides from plants are presented. Part II discusses database-aided peptide prediction and design methods, synthetic combinatorial libraries and peptide mimetics that expand the conformational space of natural antimicrobial peptides. Part III covers the biophysical and structural characterization of antimicrobial peptides and their complexes. Finally, Part IV focuses on novel strategies for developing peptide-based therapies.

Progress in Biopolymer Research

Progress in Biopolymer Research Book
Author : Pablo C. Sánchez
Publisher : Nova Science Pub Incorporated
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

This book presents new and important research on biopolymers which are a special class of polymers produced by living organisms. Starch, proteins and peptides, DNA, and RNA are all examples of biopolymers, in which the monomer units, respectively, are sugars, amino acids, and nucleic acids.A major but defining difference between polymers and biopolymers can be found in their structures. Polymers, including biopolymers, are made of repetitive units called monomers. Biopolymers inherently have a well defined structure: The exact chemical composition and the sequence in which these units are arranged is called the primary structure. Many biopolymers spontaneously fold into characteristic compact shapes (see also "protein folding" as well as secondary structure and tertiary structure), which determine their biological functions and depend in a complicated way on their primary structures. Structural biology is the study of the structural properties of the biopolymers. In contrast most synthetic polymers have much simpler and more random (or statistic) structures.

Amino Acids Peptides and Proteins in Organic Chemistry Protection Reactions Medicinal Chemistry Combinatorial Synthesis

Amino Acids  Peptides and Proteins in Organic Chemistry  Protection Reactions  Medicinal Chemistry  Combinatorial Synthesis Book
Author : Anonim
Publisher : John Wiley & Sons
Release : 2011-06-03
ISBN : 3527641572
Language : En, Es, Fr & De

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Book Description :

This is the fourth of five books in the Amino Acids, Peptides and Proteins in Organic Synthesis series. Closing a gap in the literature, this is the only series to cover this important topic in organic and biochemistry. Drawing upon the combined expertise of the international "who's who" in amino acid research, these volumes represent a real benchmark for amino acid chemistry, providing a comprehensive discussion of the occurrence, uses and applications of amino acids and, by extension, their polymeric forms, peptides and proteins. The practical value of each volume is heightened by the inclusion of experimental procedures. The 5 volumes cover the following topics: Volume 1: Origins and Synthesis of Amino Acids Volume 2: Modified Amino Acids, Organocatalysis and Enzymes Volume 3: Building Blocks, Catalysis and Coupling Chemistry Volume 4: Protection Reactions, Medicinal Chemistry, Combinatorial Synthesis Volume 5: Analysis and Function of Amino Acids and Peptides The fourth volume in this series is structured in three main sections. The first section is about protection reactions and amino acid based peptidomimetics. The second, and most extensive, part is devoted to the medicinal chemistry of amino acids. It includes, among others, the chemistry of alpha- and beta amino acids, peptide drugs, and advances in N- and O-glycopeptide synthesis. The final part deals with amino acids in combinatorial synthesis. Methods, such as phage display, library peptide synthesis, and computational design are described. Originally planned as a six volume series, Amino Acids, Peptides and Proteins in Organic Chemistry now completes with five volumes but remains comprehensive in both scope and coverage. Further information about the 5 Volume Set and purchasing details can be viewed here.

Biopolymers for Biomedical and Biotechnological Applications

Biopolymers for Biomedical and Biotechnological Applications Book
Author : Bernd H. A. Rehm,M. Fata Moradali
Publisher : John Wiley & Sons
Release : 2021-01-26
ISBN : 3527345302
Language : En, Es, Fr & De

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Book Description :

Provides insight into biopolymers, their physicochemical properties, and their biomedical and biotechnological applications This comprehensive book is a one-stop reference for the production, modifications, and assessment of biopolymers. It highlights the technical and methodological advancements in introducing biopolymers, their study, and promoted applications. "Biopolymers for Biomedical and Biotechnological Applications" begins with a general overview of biopolymers, properties, and biocompatibility. It then provides in-depth information in three dedicated sections: Biopolymers through Bioengineering and Biotechnology Venues; Polymeric Biomaterials with Wide Applications; and Biopolymers for Specific Applications. Chapters cover: advances in biocompatibility; advanced microbial polysaccharides; microbial cell factories for biomanufacturing of polysaccharides; exploitation of exopolysaccharides from lactic acid bacteria; and the new biopolymer for biomedical application called nanocellulose. Advances in mucin biopolymer research are presented, along with those in the synthesis of fibrous proteins and their applications. The book looks at microbial polyhydroxyalkanoates (PHAs), as well as natural and synthetic biopolymers in drug delivery and tissue engineering. It finishes with a chapter on the current state and applications of, and future trends in, biopolymers in regenerative medicine. * Offers a complete and thorough treatment of biopolymers from synthesis strategies and physiochemical properties to applications in industrial and medical biotechnology * Discusses the most attracted biopolymers with wide and specific applications * Takes a systematic approach to the field which allows readers to grasp and implement strategies for biomedical and biotechnological applications "Biopolymers for Biomedical and Biotechnological Applications" appeals to biotechnologists, bioengineers, and polymer chemists, as well as to those working in the biotechnological industry and institutes.

Tailor Made and Functionalized Biopolymer Systems

Tailor Made and Functionalized Biopolymer Systems Book
Author : Hriday Bera,Buddhadev Layek,Jagdish Singh
Publisher : Woodhead Publishing
Release : 2021-07-30
ISBN : 0128214570
Language : En, Es, Fr & De

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Book Description :

Tailor-Made and Functionalized Biopolymer Systems: For Drug Delivery and Biomedical Applications covers the design and application of these functionalized and tailor-made biopolymers and biopolymer systems intended for drug delivery and biomedical applications. Various concepts, design protocols and biomedical applications of tailor-made biopolymer systems are covered, guiding the reader from theoretical knowledge to practical application. Authored by an array of experts from global institutions, this book offers an interdisciplinary approach to how tailor-made biopolymers lead to novel drug delivery and treatment solutions. This will be a useful reference to a broad audience, including biomedical engineers, materials scientists, pharmacologists and chemists. Provides a concise overview of tailor-made and functionalized biopolymer systems for biomedical applications Covers a range of modified biopolymers, biopolymeric composites and biopolymer-based systems in drug delivery, development of artificial organs, diagnostic applications, and more Describes characterization, synthesis and functionalization of biopolymers and biopolymers systems

Frontiers in Protein and Peptide Sciences

Frontiers in Protein and Peptide Sciences Book
Author : Ben Dunn
Publisher : Bentham Science Publishers
Release : 2014-07-28
ISBN : 160805862X
Language : En, Es, Fr & De

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Book Description :

Frontiers in Protein and Peptide Sciences is a book series focused on leading-edge research on the structure, physical properties, and functions of proteins and peptides. Authors of contributions in this series have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in the field of protein and peptide chemistry and molecular biology, including membrane proteins and their interactions with ligands, computational methods, and proteins in disease and biotechnology. The series is essential reading for protein chemists and researchers seeking the latest information about protein and peptide research.

Protein and Peptide Nanoparticles for Drug Delivery

Protein and Peptide Nanoparticles for Drug Delivery Book
Author : Anonim
Publisher : Academic Press
Release : 2015-03-26
ISBN : 012802870X
Language : En, Es, Fr & De

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Book Description :

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in a wide bioscience area Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Protein and Peptide Folding Misfolding and Non Folding

Protein and Peptide Folding  Misfolding  and Non Folding Book
Author : Reinhard Schweitzer-Stenner
Publisher : John Wiley & Sons
Release : 2012-02-08
ISBN : 1118183355
Language : En, Es, Fr & De

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Book Description :

Sheds new light on intrinsically disordered proteins andpeptides, including their role in neurodegenerative diseases With the discovery of intrinsically disordered proteins andpeptides (IDPs), researchers realized that proteins do notnecessarily adopt a well defined secondary and tertiary structurein order to perform biological functions. In fact, IDPs playbiologically relevant roles, acting as inhibitors, scavengers, andeven facilitating DNA/RNA-protein interactions. Due to theirpropensity for self-aggregation and fibril formation, some IDPs areinvolved in neurodegenerative diseases such as Parkinson's andAlzheimer's. With contributions from leading researchers, this text reviewsthe most recent studies, encapsulating our understanding of IDPs.The authors explain how the growing body of IDP research isbuilding our knowledge of the folding process, the binding ofligands to receptor molecules, and peptide self-aggregation.Readers will discover a variety of experimental, theoretical, andcomputational approaches used to better understand the propertiesand function of IDPs. Moreover, they'll discover the role of IDPsin human disease and as drug targets. Protein and Peptide Folding, Misfolding, and Non-Folding beginswith an introduction that explains why research on IDPs hassignificantly expanded in the past few years. Next, the book isdivided into three sections: Conformational Analysis of Unfolded States Disordered Peptides and Molecular Recognition Aggregation of Disordered Peptides Throughout the book, detailed figures help readers understandthe structure, properties, and function of IDPs. References at theend of each chapter serve as a gateway to the growing body ofliterature in the field. With the publication of Protein and Peptide Folding, Misfolding,and Non-Folding, researchers now have a single place to discoverIDPs, their diverse biological functions, and the many disciplinesthat have contributed to our evolving understanding of them.

Enzymatic Stabilization and Formation of Food Nano and Microstructures

Enzymatic Stabilization and Formation of Food Nano  and Microstructures Book
Author : Benjamin Zeeb
Publisher : Logos Verlag Berlin GmbH
Release : 2015-03-05
ISBN : 3832539220
Language : En, Es, Fr & De

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Book Description :

Der Einsatz vernetzungsfähiger Enzyme wurde am Beispiel einer Laccase bzw. Transglutaminase zur Stabilisierung und Modifizierung neuer Verkapselungssysteme untersucht. Ziel der Studien war es insbesondere den Wirkmechanismus der vernetzenden Enzyme in komplexen Lebensmittelmatrizen zu klären. Im Fokus der Forschung stand die Wirkung der Oxidase Laccase auf eine Fischgelatine-Zuckerrübenpektin-stabilisierte Öl-in-Wasser-Emulsion. Die Ergebnisse belegen, dass ausschließlich Biopolymere, die an der unmittelbar zur kontinuierlichen Phase hin zugänglichen Grenzfläche der Öl-in-Wasser Emulsionen durch die Laccase vernetzt werden konnten. In konzentrierten Emulsionssystemen können vernetzende Enzyme neben der Katalyse kovalenter Bindungen innerhalb der Grenzflächenmembran auch Tropfen-Tropfen-Netzwerke induzieren. Die Ausbildung partikulärer Emulsionsgele hängt dabei wesentlich vom mittleren Abstand der Emulsionstropfen ab. Diese Dissertation hat gezeigt, dass vernetzende Enzyme wie Laccase oder Transglutaminase in der Lage sind, die Struktur und Eigenschaften von Lebensmitteldispersion zu modifizieren.

Biopolymer Research Trends

Biopolymer Research Trends Book
Author : Tamás S. Németh
Publisher : Nova Publishers
Release : 2007
ISBN : 9781600219832
Language : En, Es, Fr & De

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Book Description :

Biopolymers are a special class of polymers produced by living organisms. Starch, proteins and peptides, DNA, and RNA are all examples of biopolymers, in which the monomer units, respectively, are sugars, amino acids, and nucleic acids.A major but defining difference between polymers and biopolymers can be found in their structures. Polymers, including biopolymers, are made of repetitive units called monomers. Biopolymers inherently have a well defined structure: The exact chemical composition and the sequence in which these units are arranged is called the primary structure. Many biopolymers spontaneously fold into characteristic compact shapes (see also "protein folding" as well as secondary structure and tertiary structure), which determine their biological functions and depend in a complicated way on their primary structures. Structural biology is the study of the structural properties of the biopolymers. In contrast most synthetic polymers have much simpler and more random (or statistic) structures. This book presents leading-edge research from around the world in this dynamic field.

Peptide and Protein Drug Analysis

Peptide and Protein Drug Analysis Book
Author : Ronald Reid
Publisher : CRC Press
Release : 1999-11-12
ISBN : 9781420001334
Language : En, Es, Fr & De

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Book Description :

Furthering efforts to simulate the potency and specificity exhibited by peptides and proteins in healthy cells, this remarkable reference supplies pharmaceutical scientists with a wealth of techniques for tapping the enormous therapeutic potential of these molecules-providing a solid basis of knowledge for new drug design. Provides a broad, comprehensive overview of peptides and proteins as mediators of cell movement, proliferation, differentiation, and communication. Written by more than 50 leading international authorities, Peptides and Protein Drug Analysis discusses strategies for dealing with the complexity of peptides and proteins in conformational flexibility and amino acid sequence variability analyzes drug formulations facilitated by solid-phase peptide synthesis and recombinant DNA technology examines chemical purity analysis by high-pressure chromatographic, capillary electrophoretic, gel electrophoretic, and isoelectric focusing methods highlights drug design elements derived from protein folding, bioinformatics, and computational chemistry demonstrates uses of unnatural mutagenesis and combinatorial chemistry explores mass spectrometry, protein sequence, and carbohydrate analysis illustrates bioassays and other new functional analysis methods surveys spectroscopic techniques such as ultraviolet, fluorescence, Fourier transform infrared, and nuclear magnetic resonance (NMR) addresses ways of distinguishing between levels of therapeutic and endogenous agents in cells reviews structural analysis tools such as ultracentrifugation and light, X-ray, and neutron scattering and more! Featuring over 3400 bibliographic citations and more than 500 tables, equations, and illustrations, Peptide and Protein Drug Analysis is a must-read resource for pharmacists; pharmacologists; analytical, organic, and pharmaceutical chemists; cell and molecular biologists; biochemists; and upper-level undergraduate and graduate students in these disciplines.

Food biopolymers Structural functional and nutraceutical properties

Food biopolymers  Structural  functional and nutraceutical properties Book
Author : Adil Gani,Bilal Ahmad Ashwar
Publisher : Springer Nature
Release : 2021-02-11
ISBN : 3030270610
Language : En, Es, Fr & De

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Book Description :

Food biopolymers: Structural, functional and nutraceutical properties provides valuable coverage of all major food biopolymers from plant, animal and marine sources. The text focuses on the structural characteristics of biopolymers including starch, non-starch polysaccharides, proteins and fats. A full section is dedicated to the nutraceutical potential and applications of these polymers. Further sections provide comprehensive overviews of the development of functional food products and important data on biopolymer behavior and nutraceutical potential during processing. Researchers hoping to gain a basic understanding of the techno-functional, nutraceutical potential and applications of food biopolymers will find a singular source with this text. The first section of this work focuses on the the structure, functions, bioactivity and applications of starches. The next chapters cover non-starch polysaccharides. Further sections are dedicated to proteins, lipids and oils. A detailed overview is provided for each, followed by application procedures, specifics on individual types, proteins and enzymes, and nutraceutical properties. This work can be used as a singular source for all relevant information on food biopolymers and their structural and functional properties, including their potential to increase food quality, improve shelf life, and reduce pollution and waste in the food industry.

Amino acids Peptides and Proteins

Amino acids  Peptides  and Proteins Book
Author : R. C. Sheppard
Publisher : Royal Society of Chemistry
Release : 1974
ISBN : 0851860443
Language : En, Es, Fr & De

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Book Description :

Download Amino acids Peptides and Proteins book written by R. C. Sheppard, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Amino Acids Peptides and Proteins

Amino Acids  Peptides and Proteins Book
Author : J S Davies
Publisher : Royal Society of Chemistry
Release : 2007-10-31
ISBN : 1847552730
Language : En, Es, Fr & De

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Book Description :

Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant specialist fields, the series creates a unique service for the active research chemist with regular critical in-depth accounts of progress in particular areas of chemistry. Historically, The Royal Society of Chemistry and its predecessor, The Chemical Society, have published reports of developments in chemistry since the end of the 19th century. By 1967 however, the sheer volume of chemistry published had become so great that it was decided to split the research into specialist areas, and the series Specialist Periodical Reports was born. Current subject areas covered are Amino Acids, Peptides and Proteins. Carbohydrate Chemistry, Catalysis, Electron Spin Resonance, Nuclear Magnetic Resonance, Organometallic Chemistry. Organophosphorus Chemistry, Photochemistry and Spectroscopic Properties of Inorganic and Organometallic Compounds. From time to time, the series has altered according to the fluctuating degrees of activity in the various fields, but these volumes remain a superb reference point for researchers.

Amino Acids Peptides and Proteins

Amino Acids  Peptides and Proteins Book
Author : R C Sheppard
Publisher : Royal Society of Chemistry
Release : 2007-10-31
ISBN : 1847557309
Language : En, Es, Fr & De

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Book Description :

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued. The current list of Specialist Periodical Reports can be seen on the inside flap of this volume.