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Biomaterials In Translational Medicine

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Biomaterials in Translational Medicine

Biomaterials in Translational Medicine Book
Author : Lei Yang,Sarit Bhaduri,Thomas J. Webster
Publisher : Academic Press
Release : 2018-11-30
ISBN : 012813478X
Language : En, Es, Fr & De

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Book Description :

Biomaterials in Translational Medicine delivers timely and detailed information on the latest advances in biomaterials and their role and impact in translational medicine. Key topics addressed include the properties and functions of these materials and how they might be applied for clinical diagnosis and treatment. Particular emphasis is placed on basic fundamentals, biomaterial formulations, design principles, fabrication techniques and transitioning bench-to-bed clinical applications. The book is an essential reference resource for researchers, clinicians, materials scientists, engineers and anyone involved in the future development of innovative biomaterials that drive advancement in translational medicine. Systematically introduces the fundamental principles, rationales and methodologies of creating or improving biomaterials in the context of translational medicine Includes the translational or commercialization status of these new biomaterials Provides the reader with enough background knowledge for a fundamental grip of the difficulties and technicalities of using biomaterial translational medicine Directs the reader on how to find other up-to-date sources (i.e. peer reviewed journals) in the field of translational medicine and biomaterials

Translational Regenerative Medicine

Translational Regenerative Medicine Book
Author : Anthony Atala,Julie Allickson
Publisher : Academic Press
Release : 2014-12-01
ISBN : 0124104576
Language : En, Es, Fr & De

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Book Description :

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Biomaterials Science

Biomaterials Science Book
Author : Yitzhak Rosen,Noel Elman
Publisher : CRC Press
Release : 2012-06-06
ISBN : 1439804052
Language : En, Es, Fr & De

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Book Description :

"This book is essential when designing, developing and studying biomedical materials. provides an excellent review-from a patient, disease, and even genetic point of view-of materials engineering for the biomedical field. This well presented book strongly insists on how the materials can influence patients' needs, the ultimate drive for biomedic

Innovative Bioceramics in Translational Medicine I

Innovative Bioceramics in Translational Medicine I Book
Author : Andy H. Choi,Besim Ben-Nissan
Publisher : Springer Nature
Release : 2022-01-01
ISBN : 9811674353
Language : En, Es, Fr & De

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Book Description :

This book is part of a two-part volume book that highlights the latest advances in innovative bioceramics applied in the highly interdisciplinary area referred to as “translational medicine”. This volume covers the basic principles and techniques used in the manufacture of bioceramics and biocomposites for various biomedical applications including drug delivery, implantable bionics and the development of the cardiac pacemaker, and bone tissue engineering. Furthermore, self-healing materials have been attracting increasing interest in both engineering and medical applications during the past two decades. Self-healing hydrogels are particularly interesting because of their ability to repair structural damages and recover their original functions, specifically in tissue engineering.

Regenerative Engineering

Regenerative Engineering Book
Author : Yusuf Khan,Cato T. Laurencin
Publisher : CRC Press
Release : 2018-04-19
ISBN : 1498738257
Language : En, Es, Fr & De

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Book Description :

This book focuses on advances made in both materials science and scaffold development techniques, paying close attention to the latest and state-of-the-art research. Chapters delve into a sweeping variety of specific materials categories, from composite materials to bioactive ceramics, exploring how these materials are specifically designed for regenerative engineering applications. Also included are unique chapters on biologically-derived scaffolding, along with 3D printing technology for regenerative engineering. Features: Covers the latest developments in advanced materials for regenerative engineering and medicine. Each chapter is written by world class researchers in various aspects of this medical technology. Provides unique coverage of biologically derived scaffolding. Includes separate chapter on how 3D printing technology is related to regenerative engineering. Includes extensive references at the end of each chapter to enhance further study.

Engineering in Translational Medicine

Engineering in Translational Medicine Book
Author : Weibo Cai
Publisher : Springer Science & Business Media
Release : 2013-12-19
ISBN : 1447143728
Language : En, Es, Fr & De

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Book Description :

This book covers a broad area of engineering research in translational medicine. Leaders in academic institutions around the world contributed focused chapters on a broad array of topics such as: cell and tissue engineering (6 chapters), genetic and protein engineering (10 chapters), nanoengineering (10 chapters), biomedical instrumentation (4 chapters), and theranostics and other novel approaches (4 chapters). Each chapter is a stand-alone review that summarizes the state-of-the-art of the specific research area. Engineering in Translational Medicine gives readers a comprehensive and in-depth overview of a broad array of related research areas, making this an excellent reference book for scientists and students both new to engineering/translational medicine and currently working in this area. The ability for engineering approaches to change biomedical research are increasing and having significant impact. Development of basic assays and their numerous applications are allowing for many new discoveries and should eventually impact human health. This book brings together many diverse yet related topics to give the reader a solid overview of many important areas that are not found together elsewhere. Dr. Weibo Cai has taken great care to select key research leaders of many sub-disciplines who have put together very detailed chapters that are easy to read yet highly rich in content. _______________ This book brings together many diverse yet related topics to give the reader a solid overview of many important areas that are not found together elsewhere. Dr. Weibo Cai has taken great care to select key research leaders of many sub-disciplines who have put together very detailed chapters that are easy to read yet highly rich in content. It is very exciting to see such a great set of chapters all together to allow one to have a key understanding of many different areas including cell, gene, protein, and nano engineering as well as the emerging field of theranostics. I am sure the readers will find this collection of important chapters helpful in their own research and understanding of how engineering has and will continue to play a critical role in biomedical research and clinical translation. Sanjiv Sam Gambhir M.D., Ph.D. Stanford University, USA Engineering in Translational Medicine is a landmark book bridging the fields of engineering and medicine with a focus on translational technologies and methods. In a single, well-coordinated volume, this book brings together contributions from a strong and international scientific cast, broadly covering the topics. The book captures the tremendous opportunities made possible by recent developments in bioengineering, and highlights the potential impact of these advances across a broad spectrum of pressing health care needs. The book can equally serve as a text for graduate level courses, a reference source, a book to be dipped into for pleasure by those working within the field, or a cover-to-cover read for those wanting a comprehensive, yet readable introduction to the current state of engineering advances and how they are impacting translational medicine. Simon R. Cherry, Ph.D. University of California, Davis, USA

Biomaterials from Nature for Advanced Devices and Therapies

Biomaterials from Nature for Advanced Devices and Therapies Book
Author : Nuno M. Neves,Rui L. Reis
Publisher : John Wiley & Sons
Release : 2016-10-07
ISBN : 1119178088
Language : En, Es, Fr & De

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Book Description :

In-depth information on natural biomaterials and their applications for translational medicine! Undiluted expertise: edited by world-leading experts with contributions from top-notch international scientists, collating experience and cutting-edge knowledge on natural biomaterials from all over the world A must-have on the shelf in every biomaterials lab: graduate and PhD students beginning their career in biomaterials science and experienced researchers and practitioners alike will turn to this comprehensive reference in their daily work Link to clinical practice: chapters on translational research make readers aware of what needs to be considered when a biomaterial leaves the lab to be routinely used

Translating Biomaterials for Bone Graft

Translating Biomaterials for Bone Graft Book
Author : Joo L. Ong,Teja Guda
Publisher : CRC Press
Release : 2017-01-06
ISBN : 1315363518
Language : En, Es, Fr & De

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Book Description :

Translating Biomaterials for Bone Graft: Bench-top to Clinical Applications brings together the current translational research in bone tissue engineering, from design to application – from materials, drugs and biologic delivery used for bone graft applications to pre-clinical and clinical considerations. The book also discusses the regulatory approval pathways, which involves consideration of the class of devices; whether they are similar to existing solutions, minimal manipulation of donor tissue or completely novel materials, drugs and biologics. These considerations drive the ability to successfully transition the latest generations of bone graft materials into the clinics. Chapters come from materials scientists, clinicians, researchers, and consultants and provide a holistic understanding of the field. As such, the book is a state-of-the-art reference to bone therapies and should appeal to clinicians, scientists, as well as students interested in the current research and/or practices in the field of bone regeneration and restoration.

Synthesis Functionalization and Clinical Translation of Pharmaceutical Biomaterials

Synthesis  Functionalization  and Clinical Translation of Pharmaceutical Biomaterials Book
Author : Jianxun Ding,Mingqiang Li,Shixian Lv
Publisher : Frontiers Media SA
Release : 2021-08-18
ISBN : 2889711935
Language : En, Es, Fr & De

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Book Description :

Download Synthesis Functionalization and Clinical Translation of Pharmaceutical Biomaterials book written by Jianxun Ding,Mingqiang Li,Shixian Lv, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Innovative Bioceramics in Translational Medicine II

Innovative Bioceramics in Translational Medicine II Book
Author : Andy H. Choi
Publisher : Springer Nature
Release : 2022-08-10
ISBN : 9811674396
Language : En, Es, Fr & De

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Book Description :

Download Innovative Bioceramics in Translational Medicine II book written by Andy H. Choi, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Nanoengineered Biomaterials for Regenerative Medicine

Nanoengineered Biomaterials for Regenerative Medicine Book
Author : Masoud Mozafari,Jayakumar Rajadas,David Kaplan
Publisher : Elsevier
Release : 2018-09-17
ISBN : 0128133562
Language : En, Es, Fr & De

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Book Description :

Nanoengineered Biomaterials for Regenerative Medicine showcases the advances that have taken place in recent years as an increasing number of nanoengineered biomaterials have been targeted to various organ tissues. The book systematically explores how nanoengineered biomaterials are used in different aspects of regenerative medicine, including bone regeneration, brain tissue reconstruction and kidney repair. It is a valuable reference resource for scientists working in biomaterials science who want to learn more about how nanoengineered materials are practically applied in regenerative medicine. Nanoengineered biomaterials have gained particular focus due to their many advantages over conventional techniques for tissue repair. As a wide range of biomaterials and nanotechnology techniques have been examined for the regeneration of tissues, this book highlights the discussions and advancements made. Provides a digestible reference source for surgeons and physicians who want to learn more on nanoengineered biomaterials and their use in effective medical treatments Offers systematic coverage on how nanoengineered biomaterials are used for different types of medicine Assesses the benefits and drawbacks of the use of bioengineered nanomaterials in different areas of regenerative medicine

Handbook of Harnessing Biomaterials in Nanomedicine

Handbook of Harnessing Biomaterials in Nanomedicine Book
Author : Dan Peer
Publisher : CRC Press
Release : 2012-01-12
ISBN : 9814316466
Language : En, Es, Fr & De

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Book Description :

This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.

Stem Cells and Biomaterials for Regenerative Medicine

Stem Cells and Biomaterials for Regenerative Medicine Book
Author : Marek J. Los,Andrzej Hudecki,Emilia Wiechec
Publisher : Academic Press
Release : 2018-11-07
ISBN : 0128122781
Language : En, Es, Fr & De

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Book Description :

Stem Cells and Biomaterials for Regenerative Medicine addresses the urgent need for a compact source of information on both the cellular and biomaterial aspects of regenerative medicine. By developing a mutual understanding between three separately functioning areas of science—medicine, the latest technology, and clinical economics—the volume encourages interdisciplinary relationships that will lead to solutions for the significant challenges faced by today's regenerative medicine. Users will find sections on the homeostatic balance created by apoptosis and proliferating tissue stem cells, the naturally regenerative capacities of various tissue types, the potential regenerative benefits of iPS-generation, various differentiation protocols, and more. Written in easily accessbile language, this volume is appropriate for any professional or medical staff looking to expand their knowledge with regard to stem cells and regenerative medicine. Arms readers with key information on tissue engineering, artificial organs and biomaterials, while using broadly accessible language Provides broad introduction to, and examples of, various types of stem cells, core concepts of regenerative medicine, biomaterials, nanotechnology and nanomaterials, somatic cell transdyferentiation, and more Edited and authored by researchers with expertise in regenerative medicine, (cancer) stem cells, biomaterials, genetics and nanomaterials

Biomaterials Science

Biomaterials Science Book
Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
Publisher : Academic Press
Release : 2020-05-23
ISBN : 0128161388
Language : En, Es, Fr & De

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Book Description :

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters

Biomaterials for Vasculogenesis and Angiogenesis

Biomaterials for Vasculogenesis and Angiogenesis Book
Author : Saeid Kargozar,Masoud Mozafari
Publisher : Woodhead Publishing
Release : 2022-06-01
ISBN : 0128218681
Language : En, Es, Fr & De

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Book Description :

Biomaterials for Angiogenesis and Vasculogenesis covers the application of materials designed to encourage new blood vessel formation. Angiogenesis and vasculogenesis play an important role in tissue engineering and regenerative medicine research by promoting vascular networks inside engineered tissues and thereby increasing tissue healing and regeneration. However, researchers are faced with the challenge of finding suitable materials for improving angiogenesis and vascular formation in assays. This book reviews a broad range of biomaterials for the promotion of blood vessel genesis, from polymers and bioactive glass, to nanomaterial scaffolds and 3D angiogenic constructs. In addition, the book covers a variety of applications for biomaterials in tissue repair and regeneration, including cardiovascular regeneration, liver tissue engineering and much more. It will serve as a detailed reference for researchers in academia and industry, working in the fields of biomedical science and engineering, materials science, regenerative medicine and translational medicine. Introduces readers to the molecular and cellular basis of angiogenesis and vasculogenesis Helps researchers find suitable biomaterials to promote angiogenesis in engineered tissues and assays Describes a range of biomaterials and their properties, including glass-ceramics, nano-carriers, polymers, and more

Cell Biology and Translational Medicine Volume 3

Cell Biology and Translational Medicine  Volume 3 Book
Author : Kursad Turksen
Publisher : Springer
Release : 2018-11-28
ISBN : 3030041859
Language : En, Es, Fr & De

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Book Description :

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the third volume of a continuing series.

Biomaterials in Clinical Practice

Biomaterials in Clinical Practice Book
Author : Fatima Zivic,Saverio Affatato,Miroslav Trajanovic,Matthias Schnabelrauch,Nenad Grujovic,Kwang Leong Choy
Publisher : Springer
Release : 2017-10-20
ISBN : 3319680250
Language : En, Es, Fr & De

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Book Description :

This book covers the properties of biomaterials that have found wide clinical applications, while also reviewing the state-of-the-art in the development towards future medical applications, starting with a brief introduction to the history of biomaterials used in hip arthroplasty. The book then reviews general types of biomaterials – polymers, ceramics, and metals, as well as different material structures such as porous materials and coatings and their applications – before exploring various current research trends, such as biodegradable and porous metals, shape memory alloys, bioactive biomaterials and coatings, and nanometals used in the diagnosis and therapy of cancer. In turn, the book discusses a range of methods and approaches used in connection with biomaterial properties and characterization – chemical properties, biocompatibility, in vivo behaviour characterisation, as well as genotoxicity and mutagenicity – and reviews various diagnostic techniques: histopathological analysis, imagining techniques, and methods for physicochemical and spectroscopic characterization. Properties of stent deployment procedures in cardiovascular surgeries, from aspects of prediction, development and deployment of stent geometries are presented on the basis of novel modelling approaches. The last part of the book presents the clinical applications of biomaterials, together with case studies in dentistry, knee and hip prosthesis. Reflecting the efforts of a multidisciplinary team of authors, gathering chemical engineers, medical doctors, physicists and engineers, it presents a rich blend of perspectives on the application of biomaterials in clinical practice. The book will provide clinicians with an essential review of currently available solutions in specific medical areas, also incorporating non-medical solutions and standpoints, thus offering them a broader selection of materials and implantable solutions. This work is the result of joint efforts of various academic and research institutions participating in WIMB Tempus project, 543898-TEMPUS-1-2013-1-ES-TEMPUS-JPHES, "Development of Sustainable Interrelations between Education, Research and Innovation at WBC Universities in Nanotechnologies and Advanced Materials where Innovation Means Business", co-funded by the Tempus Programme of the European Union.

Skin Tissue Engineering and Regenerative Medicine

Skin Tissue Engineering and Regenerative Medicine Book
Author : Mohammad Albanna,James H Holmes IV
Publisher : Academic Press
Release : 2016-01-14
ISBN : 012801797X
Language : En, Es, Fr & De

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Book Description :

The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. Explores cellular and molecular processes of wound healing, scar formation, and dermal repair Includes examples of animal models for wound healing and translation to the clinical world Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies

Cell Biology and Translational Medicine Volume 4

Cell Biology and Translational Medicine  Volume 4 Book
Author : Kursad Turksen
Publisher : Springer
Release : 2019-01-08
ISBN : 3030104869
Language : En, Es, Fr & De

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Book Description :

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the fourth volume of a continuing series.

Stem Cell Biology and Tissue Engineering in Dental Sciences

Stem Cell Biology and Tissue Engineering in Dental Sciences Book
Author : Ajaykumar Vishwakarma,Paul Sharpe,Songtao Shi,Murugan Ramalingam
Publisher : Academic Press
Release : 2014-11-05
ISBN : 0123977789
Language : En, Es, Fr & De

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Book Description :

Stem Cell Biology and Tissue Engineering in Dental Sciences bridges the gap left by many tissue engineering and stem cell biology titles to highlight the significance of translational research in this field in the medical sciences. It compiles basic developmental biology with keen focus on cell and matrix biology, stem cells with relevance to tissue engineering biomaterials including nanotechnology and current applications in various disciplines of dental sciences; viz., periodontology, endodontics, oral & craniofacial surgery, dental implantology, orthodontics & dentofacial orthopedics, organ engineering and transplant medicine. In addition, it covers research ethics, laws and industrial pitfalls that are of particular importance for the future production of tissue constructs. Tissue Engineering is an interdisciplinary field of biomedical research, which combines life, engineering and materials sciences, to progress the maintenance, repair and replacement of diseased and damaged tissues. This ever-emerging area of research applies an understanding of normal tissue physiology to develop novel biomaterial, acellular and cell-based technologies for clinical and non-clinical applications. As evident in numerous medical disciplines, tissue engineering strategies are now being increasingly developed and evaluated as potential routine therapies for oral and craniofacial tissue repair and regeneration. Diligently covers all the aspects related to stem cell biology and tissue engineering in dental sciences: basic science, research, clinical application and commercialization Provides detailed descriptions of new, modern technologies, fabrication techniques employed in the fields of stem cells, biomaterials and tissue engineering research including details of latest advances in nanotechnology Includes a description of stem cell biology with details focused on oral and craniofacial stem cells and their potential research application throughout medicine Print book is available and black and white, and the ebook is in full color