Biomaterials For Spinal Surgery

Book Description :

There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarizes this research and how it is being applied for the benefit of patients. After an introduction to the subject, part one reviews fundamental issues, such as spinal conditions and their pathologies, spinal loads, modeling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs while part three covers topics such as the use of injectable biomaterials for vertebroplasty and kyphoplasty and scoliosis implants. The final part of the book describes developments in regenerative therapies including the use of stem cells for intervertebral disc regeneration.

Book Description :

There have been important developments in materials and therapies for the treatment of spinal conditions. Biomaterials for spinal surgery summarises this research and how it is being applied for the benefit of patients. After an introduction to the subject, part one reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery. Part two discusses the use of bone substitutes and artificial intervertebral discs whilst part three covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty as well as scoliosis implants. The final part of the book summarises developments in regenerative therapies such as the use of stem cells for intervertebral disc regeneration. With its distinguished editors and international team of contributors, Biomaterials for spinal surgery is a standard reference for both those developing new biomaterials and therapies for spinal surgery and those using them in clinical practice. Summarises recent developments in materials and therapies for the treatment of spinal conditions and examines how it is being applied for the benefit of patients Reviews fundamental issues such as spinal conditions and their pathologies, spinal loads, modelling and osteobiologic agents in spinal surgery Discusses the use of bone substitutes and artificial intervertebral discs and covers topics such as the use of injectable biomaterials like calcium phosphate for vertebroplasty and kyphoplasty

Book Description :

Bone Repair Biomaterials: Regeneration and Clinical Applications, Second Edition, provides comprehensive reviews on materials science, engineering principles and recent advances. Sections review the fundamentals of bone repair and regeneration, discuss the science and properties of biomaterials used for bone repair, including metals, ceramics, polymers and composites, and discuss clinical applications and considerations, with chapters on such topics as orthopedic surgery, tissue engineering, implant retrieval, and ethics of bone repair biomaterials. This second edition includes more chapters on relevant biomaterials and a greatly expanded section on clinical applications, including bone repair applications in dental surgery, spinal surgery, and maxilo-facial and skull surgery. In addition, the book features coverage of long-term performance and failure of orthopedic devices. It will be an invaluable resource for researchers, scientists and clinicians concerned with the repair and restoration of bone. Provides a comprehensive review of the materials science, engineering principles and recent advances in this important area Presents new chapters on Surface coating of titanium, using bone repair materials in dental, spinal and maxilo-facial and skull surgery, and advanced manufacturing/3D printing Reviews the fundamentals of bone repair and regeneration, addressing social, economic and clinical challenges Examines the properties of biomaterials used for bone repair, with specific chapters assessing metals, ceramics, polymers and composites

Book Description :

Recent developments in surgical techniques have led to an increased demand for bone stock. Fusion enhancement, bone-void filling in tumor surgery and trauma are only a few examples. Autologous bone can be considered as the most successful bone graft material, and constitutes the accepted 'gold standard', as it combines all the properties required from the bone graft. In this book a 'state of the art in bone substitution for the spine' is presented. The general principles of bone biology and bone healing are outlined, as are recent advances in understanding and influencing bone formation. A variety of substitutes are described and compared.

Book Description :

Download Hot Topics in Biomaterials book written by Future Science Ltd, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Ch. 1. The Debate of Fusion and Non-fusion Strategies for Symptomatic Cervical Degenerative Disc Disease -- Ch. 2. The debate of Fusion and Non-fusion Strategies for Symptomatic Lumbar Degenerative Disc Disease -- Ch. 3. History of Spinal Fusion -- Ch. 4. History of Motion-Sparing Surgery -- Ch. 5. Anatomy -- Ch. a. Cervical Spine -- Ch. b. Lumbar Spine -- Ch. 6. Spinal Biomechanics -- Ch. 7. Spinal Imaging Intervertebral Disc and Facet Degeneration -- Ch. 8. The Effects of Fusion and Motion Sparing Procedures on the Biomechanics of the Spine -- Ch. 9. Biomaterials in Spinal Arthroplasty -- Ch. 10. Total Disc Athroplasty: Clinical Indications and Surgical Approach -- Ch. a. Cervical Spine -- Ch. b. Lumbar Spine -- Ch. 11. Cervical Arthroplasty: Biomechanics, Design Considerations, Clinical Outcome -- Ch. a. Overview of Cervical Arthroplasty: Biomechanics and Design Considerations -- Ch. b. Bryan Disc -- Ch. c. Prestige Disc, LP -- Ch. d. Prodisc C -- Ch. e. PCM -- Ch. 12. Posterior Cervical Motion Sparing Technology- Biomechanics, Design Considerations, and Clinical Outcome -- Ch. 13. Lumbar Anular and Intra-discal Treatment for Degenerative Disc Disease -- Ch. a. Genetic Engineering -- Ch. b. Anular Repair: Anulex Tech and Barricaid Intrinsic Therapeutic -- Ch. c. Nucleoplasty -- Ch. 14. Lumbar Nucleus Pulposus Replacement -- Ch. a. Ray Medica PDN -- Ch. b. Neudisc-Replication Medica -- Ch. c. Nucore-Spinewave -- Ch. d. Nautilus -- Ch. e. Newcleus (Spiral) -- Ch. f. DASCOR-Disc Dynamics -- Ch. g. Sinitec-Depuy Spine Sinux -- Ch. h. Biomet-EBI -- Ch. i. Biodisc-Cryolife -- Ch. j. Aquarelle-Stryker -- Ch. 15. Lumbar Disc Arthroplasty -- Biomechanics, Design Considerations, and Clinical Outcome -- Ch. a. Lumbar Disc Arthroplasty Biomechanics and Design Considerations -- Ch. b. Charite -- Ch. c. Prodisc -- Ch. d. Maverick -- Ch. e. Spinecore -- Ch. f. Mobidisk -- Ch. 16. Facet Arthroplasty-Archus Orthopedics and Facet Solutions -- Ch. 17. Lumbar Posterior Motion Sparing Technology -- Ch. a. Dynamic Rodding: Globus Spiral Rod, Dynesis- Zimmer, Graf Ligomentoplasty, Scientx, and Biorthex OrthoBiom -- Ch. b. Dynamic Stenosis Management: St Francis Medical X-Stop, Spine Next Wallis, Fixano Interspinous, DIAM Medronics, and Tension Band System -- Ch. 18. Complications of Motion Sparing Surgery -- Ch. 19. Revision Strategies for Failed Cervical Arthroplasty -- Ch. 20. Revision Strategies for Failed Lumbar Arthroplasty -- Ch. 21. Retrieval Analysis of Arthroplasty Devices.

Book Description :

PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UHMWPE Biomaterials Handbook and Director of the Implant Research Center at Drexel University, has developed a one-stop reference covering the processing and blending of PEEK, its properties and biotribology, and the expanding range of medical implants using PEEK: spinal implants, hip and knee replacement, etc. Covering materials science, tribology and applications Provides a complete reference for specialists in the field of plastics, biomaterials, biomedical engineering and medical device design and surgical applications

Book Description :

Download Biomaterials In Orthopaedic Surgery book written by Federico Ángel Rodríguez-González, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Download Nano Biomaterials for the Delivery of Therapeutic and Biological Cues for Regenerative Medicine book written by Silvia Minardi,Hafiz M. N. Iqbal, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Book Description :

Disorders related to the intervertebral disc (IVD) are common causes of morbidity and of severe life quality deterioration. IVD degeneration, although in many cases asymptomatic, is often the origin of painful neck and back diseases. In Western societies IVD related pain and disability account for enormous health care costs as a result of work absenteeism and thus lost production, disability benefits, medical and insurance expenses. Although only a small percentage of patients with disc disorders finally will undergo surgery, spinal surgery has been one of the fastest growing disciplines in the musculoskeletal field in recent years. Nevertheless, current treatment options are still a matter of controversial discussion. In particular, they hardly can restore normal spine biomechanics and prevent degeneration of adjacent tissues. While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP). Recent emphasis has therefore been put in biological ways to regenerate the NP; however, there are a number of obstacles to overcome, considering the exceptional biological and biomechanical environment of this tissue. Different biological approaches such as molecular, gene, and cell based therapies have been investigated and have shown promising results in both in vitro and in vivo studies. Nonetheless, considerable hurdles still exist in their application for IVD regeneration in human patients. The choice of the cells and the choice of the cell carrier suitable for implantation pose major challenges for research and development activities. This lecture recapitulates the basics of IVD structure, function, and degeneration mechanisms. The first part reviews the recent progress in the field of disc and stem cell based regenerative approaches. In the second part, most appropriate biomaterials that have been evaluated as cell or molecule carrier to cope with degenerative disc disease are outlined. The potential and limitations of cell- and biomaterial-based treatment strategies and perspectives for future clinical applications are discussed. Table of Contents: Cell Therapy for Nucleus Pulposus Regeneration / Recent Advances in Biomaterial Based Tissue Engineering for Intervertebral Disc Regeneration

Book Description :

Advances in Spinal Fusion reveals a new generation of materials and devices for enhanced operations in spinal fusion. This reference showcases emerging research and technologies in areas such as biodegradable implants, drug delivery, stem cell isolation and transfection, cell encapsulation and immobilization, and the design of 2D and 3D scaffolds for cells. It captures a cascade of innovations crucial to increased healing and decreased morbidity in spinal fusion methods and mechanics and addresses current standards in analytical methodology and quality control, it describes the selection of biomaterials for improved biocompatibility, biostability, and structure/function relationships.

Book Description :

Comprehensive Biomaterials brings together the myriad facets of biomaterials into one, major series of six edited volumes that would cover the field of biomaterials in a major, extensive fashion: Volume 1: Metallic, Ceramic and Polymeric Biomaterials Volume 2: Biologically Inspired and Biomolecular Materials Volume 3: Methods of Analysis Volume 4: Biocompatibility, Surface Engineering, and Delivery Of Drugs, Genes and Other Molecules Volume 5: Tissue and Organ Engineering Volume 6: Biomaterials and Clinical Use Experts from around the world in hundreds of related biomaterials areas have contributed to this publication, resulting in a continuum of rich information appropriate for many audiences. The work addresses the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, and strategic insights for those entering and operational in diverse biomaterials applications, research and development, regulatory management, and commercial aspects. From the outset, the goal was to review materials in the context of medical devices and tissue properties, biocompatibility and surface analysis, tissue engineering and controlled release. It was also the intent both, to focus on material properties from the perspectives of therapeutic and diagnostic use, and to address questions relevant to state-of-the-art research endeavors. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance as well as future prospects Presents appropriate analytical methods and testing procedures in addition to potential device applications Provides strategic insights for those working on diverse application areas such as R&D, regulatory management, and commercial development

Book Description :

Comprehensive Biomaterials II, Second Edition brings together the myriad facets of biomaterials into one expertly-written series of edited volumes. Articles address the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, research and development, regulatory management, commercial aspects, and applications, including medical applications. Detailed coverage is given to both new and emerging areas and the latest research in more traditional areas of the field. Particular attention is given to those areas in which major recent developments have taken place. This new edition, with 75% new or updated articles, will provide biomedical scientists in industry, government, academia, and research organizations with an accurate perspective on the field in a manner that is both accessible and thorough. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance, and future prospects Covers all significant emerging technologies in areas such as 3D printing of tissues, organs and scaffolds, cell encapsulation; multimodal delivery, cancer/vaccine - biomaterial applications, neural interface understanding, materials used for in situ imaging, and infection prevention and treatment Effectively describes the many modern aspects of biomaterials from basic science, to clinical applications

Book Description :

Recent concerns over the possible effects of metal-on-metal orthopaedic implants and the evolution of more natural structures made from fibre have made medical device manufacturers consider the potential of fibre. Textiles offer the potential to replace traditional materials with novel fibres which are more suitable for many load bearing applications. Orthopaedics, in particular, is embracing textile technology for repairing, replacing, and regenerating integral pieces of the skeletal system and its associated components. This important new book will provide readers with a comprehensive overview of the role biomedical textiles can play in the orthopaedic field. Chapters in part one will discuss the fundamentals of textiles for orthopaedic applications. Part two will cover textiles for implantable orthopaedic applications whilst the final set of chapters will discuss the role of textiles in orthopaedic tissue engineering. Provides a comprehensive overview of the role biomedical textiles can play in the orthopaedic field

Book Description :

The success of any spinal operation depends on good definition of the indications, consideration of the contraindications, technical and organizational factors, good operating technique and correct preoperative preparation and positioning of the patient. These points are presented in this book as clearly as possible and are illustrated with detailed high quality artwork.

Book Description :

Total knee arthroplasty (TKA) is commonly considered to be a reliable procedure, with high implant survival rates at 10 to 15 years of follow-up. The goal of total knee replacement surgery is to relieve pain and obtain better knee function. This is achieved by ensuring correct patient selection, pre-operative deformity, implant design and accurate surgical techniques. This book covers a range of techniques for the realisation of functional joint motion and stability. The first part of the book will describe fundamentals in total knee arthroplasty and alternative procedures. The second half will look at surgical techniques and considerations whilst the final chapters will address future trends and challenges in the field of knee surgery. This book will be an essential reference for academics, orthopaedic surgeons, and those training in medicine, physiatry and rheumatology.

Book Description :

In the latest edition of Benzel’s Spine Surgery, renowned neurosurgery authority Dr. Edward C. Benzel, along with new editor Dr. Michael P. Steinmetz, deliver the most up-to-date information available on every aspect of spine surgery. Improved visuals and over 100 brand-new illustrations enhance your understanding of the text, while 26 new chapters cover today's hot topics in the field. A must-have resource for every neurosurgeon and orthopedic spine surgeon, Benzel's Spine Surgery provides the expert, step-by-step guidance required for successful surgical outcomes. Glean essential, up-to-date information in one comprehensive reference that explores the full spectrum of techniques used in spine surgery. Covers today's hot topics in spine surgery, such as pelvic parameters in planning for lumbar fusion; minimally invasive strategies for the treatment of tumors and trauma of the spine; and biologics and stem cells. A total of 18 intraoperative videos allow you to hone your skills and techniques. New editor Michael P. Steinmetz brings fresh insights and improvements to the text. Features the addition of 26 chapters, including: -Biologics in Spine Fusion Surgery -Endoscopic and Transnasal Approaches to the Craniocervical Junction -Cellular Injection Techniques for Discogenic Pain -Minimally Invasive Techniques for Thoracolumbar Deformity -Spinal Cord Herniation and Spontaneous Cerebrospinal Fluid Leak -MIS Versus Open Spine Surgery Extensive revisions to many of the existing chapters present all of the most up-to-date information available on every aspect of spine surgery. Improved visuals and over 100 brand-new illustrations enhance learning and retention.

Book Description :

Design of biomedical products / G.J. Verkerke & E.B. van der Houwen -- Animal models in biomaterials research / G. Rakhorst ... [et al.] -- Technology assessment / J.M. Hummel -- Hemocompatibility of medical devices / W. van Oeveren -- Tissue and cell interactions with (bio)materials / T.G. van Kooten & R. Kuijer -- Biomaterials-associated surgery and infection / P.G.M. Maathuis ... [et al.] -- Cardiopulmonary bypass and postoperative organ dysfunction / Y.J. Gu -- Mechanical circulatory support systems / G. Rakhorst & M.E. Erasmus -- Biomaterials-related infections in orthopedic implants / D. Neut & R.L. Diercks -- Biomaterials for voice reconstruction / G.J. Verkerke ... [et al.] -- Biomaterials in ophthalmology / V.W. Renardel de Lavalette & S.A. Koopmans -- Biomaterials in plastic surgery / M.F. Meek -- Surgical meshes : morphology-dependent bacterial colonization / A.F. Engelsman

Book Description :

Disorders related to the intervertebral disc (IVD) are common causes of morbidity and of severe life quality deterioration. IVD degeneration, although in many cases asymptomatic, is often the origin of painful neck and back diseases. In Western societies IVD related pain and disability account for enormous health care costs as a result of work absenteeism and thus lost production, disability benefits, medical and insurance expenses. Although only a small percentage of patients with disc disorders finally will undergo surgery, spinal surgery has been one of the fastest growing disciplines in the musculoskeletal field in recent years. Nevertheless, current treatment options are still a matter of controversial discussion. In particular, they hardly can restore normal spine biomechanics and prevent degeneration of adjacent tissues. While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP). Recent emphasis has therefore been put in biological ways to regenerate the NP; however, there are a number of obstacles to overcome, considering the exceptional biological and biomechanical environment of this tissue. Different biological approaches such as molecular, gene, and cell based therapies have been investigated and have shown promising results in both in vitro and in vivo studies. Nonetheless, considerable hurdles still exist in their application for IVD regeneration in human patients. The choice of the cells and the choice of the cell carrier suitable for implantation pose major challenges for research and development activities. This lecture recapitulates the basics of IVD structure, function, and degeneration mechanisms. The first part reviews the recent progress in the field of disc and stem cell based regenerative approaches. In the second part, most appropriate biomaterials that have been evaluated as cell or molecule carrier to cope with degenerative disc disease are outlined. The potential and limitations of cell- and biomaterial-based treatment strategies and perspectives for future clinical applications are discussed. Table of Contents: Cell Therapy for Nucleus Pulposus Regeneration / Recent Advances in Biomaterial Based Tissue Engineering for Intervertebral Disc Regeneration

Book Description :

Fundamental Biomaterials: Metals provides current information on the development of metals and their conversion from base materials to medical devices. Chapters analyze the properties of metals and discuss a range of biomedical applications, with a focus on orthopedics. While the book will be of great use to researchers and professionals in the development stages of design for more appropriate target materials, it will also help medical researchers understand, and more effectively communicate, the requirements for a specific application. With the recent introduction of a number of interdisciplinary bio-related undergraduate and graduate programs, this book will be an appropriate reference volume for students. It represents the second volume in a three volume set, each of which reviews the most important and commonly used classes of biomaterials, providing comprehensive information on materials properties, behavior, biocompatibility and applications. Provides current information on metals and their conversion from base materials to medical devices Includes analyses of types of metals, discussion of a range of biomedical applications, and essential information on corrosion, degradation and wear and lifetime prediction of metal biomaterials Explores both theoretical and practical aspects of metals in biomaterials