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Biomarkers Of Hip Implant Function

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Biomarkers of Hip Implant Function

Biomarkers of Hip Implant Function Book
Author : Ilona Swiatkowska
Publisher : Academic Press
Release : 2021-06-15
ISBN : 9780128215968
Language : En, Es, Fr & De

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Book Description :

Biomarkers of Hip Implant Function: Diagnostic Modalities to Prevent Chronic Periprosthetic Joint Infection and Implant Failure brings together established and potential new biomarkers, critically evaluating their clinical usefulness based on recent evidence. Researchers will benefit from a comprehensive view of the topic to identify underexplored areas. Orthopedic surgeons and general practitioners will use the book to monitor implant performance and facilitate management of their patients. Additionally, the work will benefit engineers and joint implant manufacturers to guide improvements in design. This book will also be of interest to regulators and policymakers by helping them update their guidelines on follow-ups for hip implant recipients. Nearly all orthopedic surgeons have implanted a cobalt-chromium hip and most general practitioners have at least one patient with cobalt-chromium implant on their books. The recent worldwide controversy surrounding metal-on-metal hips means that advice on how to manage patients with these implants is of great interest to these professionals. Hence, this book is a welcomed addition to the conversation. Covers all candidate biomarkers of hip implant wear and toxicity in a single source Summarizes recent research into blood titanium levels associated with well-functioning and malfunctioning hip implants to aid implant revision decisions Contains essential clinical cases and tables to illustrate points

Perspectives on Biomarker and Surrogate Endpoint Evaluation

Perspectives on Biomarker and Surrogate Endpoint Evaluation Book
Author : Institute of Medicine,Food and Nutrition Board,Board on Health Sciences Policy,Board on Health Care Services,Committee on Qualification of Biomarkers and Surrogate Endpoints in Chronic Disease
Publisher : National Academies Press
Release : 2011-01-12
ISBN : 9780309187008
Language : En, Es, Fr & De

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Book Description :

In 2010 the Institute of Medicine (IOM) recommended a framework for the evaluation of biomarkers in the chronic disease setting. Published in the book Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease, the framework is intended to bring consistency and transparency to the previously disparate process of biomarker evaluation. Following the book's release, the IOM convened a 2-day discussion forum in Washington, DC, in order to provide an opportunity for stakeholders to learn about, react to, and discuss the book. Presentations reviewed the authoring committee's work process, recommendations, and provided perspectives on the book from the point of view of participants. Thomas Fleming, professor of biostatistics and statistics at the University of Washington, gave a keynote presentation on the critical issues in the validation of surrogate endpoints, a specific use of a biomarker. The present volume recounts the discussion forum proceedings, focusing in turn on each represented sector. A summary of Dr. Fleming's presentation then sets the committee's recommendations within the context of biomarker utilization. Lastly, this summary examines the main themes raised by stakeholders, and the challenges and opportunities presented to stakeholders by the book's recommendations.

Biomarkers in Toxicology

Biomarkers in Toxicology Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2019-02-13
ISBN : 0128146567
Language : En, Es, Fr & De

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Book Description :

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Principles of Hip Arthroscopy

Principles of Hip Arthroscopy Book
Author : Shane J. Nho,Joshua D. Harris,Jaimo Ahn
Publisher : Frontiers Media SA
Release : 2017-08-16
ISBN : 2889452506
Language : En, Es, Fr & De

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Book Description :

The field of arthroscopy, originating from Denmark in 1912, has rapidly evolved to diagnose and treat a wide range of musculoskeletal pathologies. Although around for sometime, arthroscopy in the field of orthopedics has traditionally focused on the knee, shoulder, or elbow, as arthroscopy of the hip is technically challenging; the deep structures of the hip, including neurovascular bundles, require specialized training and equipment to access. However, with advances in surgical techniques, hip arthroscopy has become increasingly popular given its ability to treat pathologies with previously poor prognoses such as labral tears, hip arthritis and femoroacetabular impingement (FAI). When indicated, hip arthroscopy results in shorter recovery times, low complication rates, and excellent outcomes in quality of life and pain regardless of age, gender or activity level. The purpose of this e-book is to shed light on this expanding field by delving into the common hip pathology femoroacetabular impingement, its clinical relevance, and to explore various surgical techniques and postoperative rehabilitation. It is our hope that this textbook provides valuable knowledge to advance the field of hip arthroscopy, enhance surgical techniques, and ultimately increase the quality of patient care. Enjoy! Shane J. Nho, MD, MS Joshua D. Harris, MD Jaimo Ahn, MD, PhD

Volume 47 Issue 1 An Issue of Orthopedic Clinics

Volume 47  Issue 1  An Issue of Orthopedic Clinics  Book
Author : Asif M. Ilyas,Shital N. Parikh,Saqib Rehman,Giles R Scuderi,Felasfa M. Wodajo
Publisher : Elsevier Health Sciences
Release : 2016-01-19
ISBN : 0323414613
Language : En, Es, Fr & De

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Book Description :

Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot & ankle, and sports medicine.

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine Book
Author : Martin Wehling
Publisher : Academic Press
Release : 2021-07-15
ISBN : 032399962X
Language : En, Es, Fr & De

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Book Description :

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

Orthopedic Surgery

Orthopedic Surgery Book
Author : Zaid Al-Aubaidi,Andreas Fette
Publisher : BoD – Books on Demand
Release : 2012-03-09
ISBN : 9535102311
Language : En, Es, Fr & De

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Book Description :

Orthopaedic surgery is the widest and the strongest growing surgical specialty. It is clear, that the process of improving treatments and patients care, requires knowledge, and this requires access to studies, expert opinion and books. Unfortunately, the access to this knowledge is being materialized. As we believe that access to the medical knowledge should be reachable to everyone free of charge, this book was generated to cover the orthopaedic aspect. It will provide the reader with a mix of basic, but as well highly specialized knowledge. In the process of editing this book, my wife Jurgita has been, as usual, the most supportive person. I would like to thank her for being in my life. I would like to thank Mr. Greblo, the Publishing Process Manager, for all his help and last but not least thanks to our readers, as without them this book would have no meaning.

Cartilage Injury of the Knee

Cartilage Injury of the Knee Book
Author : Aaron J. Krych,Leela C. Biant,Andreas H. Gomoll,João Espregueira-Mendes,Alberto Gobbi,Norimasa Nakamura
Publisher : Springer Nature
Release : 2021-08-31
ISBN : 3030780511
Language : En, Es, Fr & De

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Book Description :

Cartilage injuries of the knee are common, and diagnosis and treatment options have continued to evolve. This book focuses on current non-operative and surgical treatment strategies for articular cartilage injuries, highlighting the controversies and different approaches from an international perspective. This book includes information on the basic science of cartilage structure and function, expert perspectives on imaging and diagnosing, as well as work-up of athletes and patients presenting with acute or chronic cartilage injury. It also provides an evidence base for current cutting-edge cartilage repair and restoration. Written by leading experts in the field, the book, published in collaboration with ISAKOS and ICRS, is vital reading for orthopaedic and sports medicine surgeons, fellows and residents. It is also of interest to sports trainers, physiotherapists, medical students, postgraduate students, and physical medicine and rehabilitation specialists.

Osteoarthritis

Osteoarthritis Book
Author : Mohit Kapoor,Nizar N. Mahomed
Publisher : Springer
Release : 2015-07-20
ISBN : 3319195603
Language : En, Es, Fr & De

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Book Description :

This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patient’s phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics.

Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments

Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services
Publisher : National Academies Press
Release : 2021-01-15
ISBN : 0309682630
Language : En, Es, Fr & De

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Book Description :

As part of the overall disability determination process, the Social Security Administration uses a step-by-step approach to understand how severe an individual's condition is and whether it meets program criteria for disability. The use of various types of biomarkers has been suggested as a way to strengthen the amount and quality of objective evidence available to the review process. At the request of the Social Security Administration, the National Academies of Sciences, Engineering, and Medicine's Board on Health Care Services organized a virtual workshop on July 21, 2020, titled The State of the Science of the Use of Biomarkers to Establish the Presence and Severity of Impairments. Workshop discussions focused on the current and potential uses for biomarkers; explored legal and ethical implications associated with biomarker use in clinical decision making; and considered the possible uses of nongenetic biomarkers as tools for the diagnosis or prognosis of the severity of specific physical and mental impairments. This publication summarizes the presentations and discussion of the workshop.

Joint Function Preservation

Joint Function Preservation Book
Author : Alberto Gobbi,John G. Lane,Umile Giuseppe Longo,Ignacio Dallo
Publisher : Springer Nature
Release : 2021-11-03
ISBN : 3030829588
Language : En, Es, Fr & De

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Book Description :

This user-friendly, pragmatic book discusses the normal and pathological conditions of the appendicular skeleton, with a focus on the preservation of joint function, providing a detailed overview of strategies for both common and complex joint preservation. The first section covers basic topics, ranging from joints homeostasis and biomechanics, to genetics, bio-orthopedics, tissue engineering and 3D bioprinting. The following sections are each dedicated to a specific joint – its functional anatomy, pathologic conditions, diagnostics and treatment. This book is of interest to orthopedists and sports medicine specialists treating common and complex injuries of the joints.

Metabolic Alterations in Neurodegenerative Disorders

Metabolic Alterations in Neurodegenerative Disorders Book
Author : David Baglietto-Vargas,Kristine Freude,Ines Moreno-Gonzalez,Carlos J. Rodriguez-Ortiz
Publisher : Frontiers Media SA
Release : 2022-03-14
ISBN : 2889746720
Language : En, Es, Fr & De

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Book Description :

Download Metabolic Alterations in Neurodegenerative Disorders book written by David Baglietto-Vargas,Kristine Freude,Ines Moreno-Gonzalez,Carlos J. Rodriguez-Ortiz, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

UHMWPE Biomaterials Handbook

UHMWPE Biomaterials Handbook Book
Author : Steven M. Kurtz
Publisher : William Andrew
Release : 2015-09-16
ISBN : 0323354351
Language : En, Es, Fr & De

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Book Description :

UHMWPE Biomaterials Handbook, Third Edition, describes the science, development, properties, and application of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. UHMWPE is now the material of choice for joint replacements, and is increasingly being used in fibers for sutures. This book is a one-stop reference for information on this advanced material, covering both introductory topics and the most advanced developments. The third edition adds six new chapters on a range of topics, including the latest in anti-oxidant technologies for stabilizing HXLPE and up-to-date systematic reviews of the clinical literature for HXLPE in hips and knees. The book chronicles the rise and fall of all-metal hip implants, as well as the increased use of ceramic biomaterials and UHMWPE for this application. This book also brings orthopedic researchers and practitioners up to date on the stabilization of UHMWPE with antioxidants, as well as the choices of antioxidant available for practitioners. The book also thoroughly assesses the clinical performance of HXLPE, as well as alternative bearings in knee replacement and UHMWPE articulations with polyether ether ketone (PEEK). Written and edited by the top experts in the field of UHMWPE, this is the only state-of-the-art reference for professionals, researchers, and clinicians working with this material. The only complete reference for professionals, researchers, and clinicians working with ultra-high molecular weight polyethylene biomaterials technologies for joint replacement and implants New edition includes six new chapters on a wide range of topics, including the clinical performance of highly crosslinked polyethylene (HXLPE) in hip and knee replacement, an overview of antioxidant stabilization for UHMWPE, and the medical applications of UHMWPE fibers State-of-the-art coverage of the latest UHMWPE technology, orthopedic applications, biomaterial characterization, and engineering aspects from recognized leaders in the field

Obesity New Insights for the Healthcare Professional 2013 Edition

Obesity  New Insights for the Healthcare Professional  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-07-22
ISBN : 148166722X
Language : En, Es, Fr & De

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Book Description :

Obesity: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Obesity: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Obesity: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Biomaterials Science

Biomaterials Science Book
Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
Publisher : Academic Press
Release : 2020-05-23
ISBN : 0128161388
Language : En, Es, Fr & De

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Book Description :

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for most chapters

Postgraduate Orthopaedics

Postgraduate Orthopaedics Book
Author : Paul A. Banaszkiewicz,Deiary F. Kader
Publisher : Cambridge University Press
Release : 2012-08-16
ISBN : 1139561332
Language : En, Es, Fr & De

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Book Description :

This book has been written specifically for candidates sitting the oral part of the FRCS (Tr & Orth) examination. It presents a selection of questions arising from common clinical scenarios along with detailed model answers. The emphasis is on current concepts, evidence-based medicine and major exam topics. Edited by the team behind the successful Candidate's Guide to the FRCS (Tr & Orth) Examination, the book is structured according to the four major sections of the examination; adult elective orthopaedics, trauma, children's/hands and upper limb and applied basic science. An introductory section gives general exam guidance and end section covers common diagrams that you may be asked to draw out. Each chapter is written by a recent (successful) examination candidate and the style of each reflects the author's experience and their opinions on the best tactics for first-time success. If you are facing the FRCS (Tr & Orth) you need this book.

Core Topics in General Emergency Surgery E Book

Core Topics in General   Emergency Surgery E Book Book
Author : Simon Paterson-Brown
Publisher : Elsevier Health Sciences
Release : 2013-06-24
ISBN : 0702049727
Language : En, Es, Fr & De

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Book Description :

Core Topics in General & Emergency Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of this sub-specialty that is relevant to their general surgical practice. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities. This is a title in the Companion to Specialist Surgical Practice series whose eight volumes are an established and highly regarded source of information for the specialist general surgeon. The Companion to Specialist Surgical Practice series provides a current and concise summary of the key topics within each major surgical sub-specialty. Each volume highlights evidence-based practice both in the text and within the extensive list of references at the end of every chapter. An expanded authorship team across the series includes additional European and World experts with an increased emphasis on global practice. The contents of the series have been extensively revised in line with recently published evidence. The volume contains a new chapter on the complications of bariatric surgery. This updated text will appeal to all General Surgeons who wish to keep up to date in both elective and emergency conditions, while providing the relevant information for the Specialist Surgeon who is still required to look after undifferentiated emergencies and carry out routine elective general surgical procedures.

Core Topics in General Emergency Surgery E Book

Core Topics in General   Emergency Surgery E Book Book
Author : Simon Paterson-Brown,Hugh M. Paterson
Publisher : Elsevier Health Sciences
Release : 2018-04-25
ISBN : 070207246X
Language : En, Es, Fr & De

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Book Description :

Core Topics in General and Emergency Surgery meets the needs of surgeons in higher training and practising consultants for a contemporary and evidence-based account of general surgery in both elective and emergency situations. It is a practical reference source incorporating the most current information on recent developments, management issues and operative procedures. The text is thoroughly referenced and supported by evidence-based recommendations wherever possible, distinguishing between strong evidence to support a conclusion, and evidence suggesting that a recommendation can be reached on the balance of probabilities. For this Sixth Edition the authorship team across the series has been expanded to include additional European and World experts, with an increased emphasis on global practice. Throughout all six volumes the contents have been extensively revised in line with recently published evidence. Detailed supportive key references are provided and are also included within the comprehensive list of references in the accompanying ebook. Links to recommended online videos have been added where appropriate. The Companion to Specialist Surgical Practice series provides a current and concise summary of the key topics within the major sub-specialties of general surgery. Each volume highlights evidence-based practice both in the text and within the extensive list of references at the end of every chapter. The extensive revisions to this edition of Core Topics in General and Emergency Surgery are intended to maximize its appeal to all those in general surgical practice. There are several entirely new chapters on subjects previously covered in other volumes of the series, while the remaining chapters have been revised, updated or re-written by new authors where appropriate. The new chapters include those on the Evaluation of surgical literature; Enhanced recovery; Organ donation and general surgery in transplant patients; and Principles of neck surgery for the general surgeon. For the first time this volume includes a chapter on Patient safety and human factors in surgery, which distills the core knowledge that is fundamental to achieving good outcomes (and avoiding bad ones) in practice for all grades of surgeon.

Nutrition in the Regulation of Muscle Development and Repair

Nutrition in the Regulation of Muscle Development and Repair Book
Author : Olasunkanmi Adegoke,Xing Fu,Yan Huang
Publisher : Frontiers Media SA
Release : 2022-03-15
ISBN : 2889746992
Language : En, Es, Fr & De

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Book Description :

Download Nutrition in the Regulation of Muscle Development and Repair book written by Olasunkanmi Adegoke,Xing Fu,Yan Huang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

General Trauma Care and Related Aspects

General Trauma Care and Related Aspects Book
Author : Hans-Jörg Oestern,Otmar Trentz,Selman Uranues
Publisher : Springer Science & Business Media
Release : 2013-10-22
ISBN : 3540881247
Language : En, Es, Fr & De

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Book Description :

There currently is a clear tendency to an increasing number of accidental injuries in elderly people, in sport injuries and car crashes also in countries which recently joined the European Union and candidates to join the European Union. Patients expect very good functional results even after serious injuries. But in contrast to this development, Trauma Surgery as an independent field, is not yet established in all European countries. Therefore, it seems mandatory to compile a book that covers the state-of-the-art in Trauma Surgery. The book also serves to harmonise the practice of Trauma Surgery within the European Union, and to prepare for the exam of the U.E.M.S.