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Biomarkers Of Hip Implant Function

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Biomarkers of Hip Implant Function

Biomarkers of Hip Implant Function Book
Author : Ilona Swiatkowska
Publisher : Academic Press
Release : 2021-06-15
ISBN : 9780128215968
Language : En, Es, Fr & De

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Book Description :

Biomarkers of Hip Implant Function: Diagnostic Modalities to Prevent Chronic Periprosthetic Joint Infection and Implant Failure brings together established and potential new biomarkers, critically evaluating their clinical usefulness based on recent evidence. Researchers will benefit from a comprehensive view of the topic to identify underexplored areas. Orthopedic surgeons and general practitioners will use the book to monitor implant performance and facilitate management of their patients. Additionally, the work will benefit engineers and joint implant manufacturers to guide improvements in design. This book will also be of interest to regulators and policymakers by helping them update their guidelines on follow-ups for hip implant recipients. Nearly all orthopedic surgeons have implanted a cobalt-chromium hip and most general practitioners have at least one patient with cobalt-chromium implant on their books. The recent worldwide controversy surrounding metal-on-metal hips means that advice on how to manage patients with these implants is of great interest to these professionals. Hence, this book is a welcomed addition to the conversation. Covers all candidate biomarkers of hip implant wear and toxicity in a single source Summarizes recent research into blood titanium levels associated with well-functioning and malfunctioning hip implants to aid implant revision decisions Contains essential clinical cases and tables to illustrate points

Volume 47 Issue 1 An Issue of Orthopedic Clinics

Volume 47  Issue 1  An Issue of Orthopedic Clinics  Book
Author : Asif M. Ilyas,Shital N. Parikh,Saqib Rehman,Giles R Scuderi,Felasfa M. Wodajo
Publisher : Elsevier Health Sciences
Release : 2016-01-19
ISBN : 0323414613
Language : En, Es, Fr & De

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Book Description :

Each issue of Orthopedic Clinics offers clinical review articles on the most cutting edge technologies, techniques, and more in the field. Major topic areas include: adult reconstruction, upper extremity, pediatrics, trauma, oncology, hand, foot & ankle, and sports medicine.

Advances in Intelligent Data Analysis XV

Advances in Intelligent Data Analysis XV Book
Author : Henrik Boström,Arno Knobbe,Carlos Soares,Panagiotis Papapetrou
Publisher : Springer
Release : 2016-09-23
ISBN : 3319463497
Language : En, Es, Fr & De

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Book Description :

This book constitutes the refereed conference proceedings of the 15th International Conference on Intelligent Data Analysis, which was held in October 2016 in Stockholm, Sweden. The 36 revised full papers presented were carefully reviewed and selected from 75 submissions. The traditional focus of the IDA symposium series is on end-to-end intelligent support for data analysis. The symposium aims to provide a forum for inspiring research contributions that might be considered preliminary in other leading conferences and journals, but that have a potentially dramatic impact.

Biomarkers in Toxicology

Biomarkers in Toxicology Book
Author : Ramesh C. Gupta
Publisher : Academic Press
Release : 2019-02-13
ISBN : 0128146567
Language : En, Es, Fr & De

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Book Description :

Biomarkers in Toxicology, Second Edition, is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This revised and completely updated edition includes both vertebrate and non-vertebrate species models for toxicological testing and the development of biomarkers. Divided into several key sections, this reference volume contains new chapters devoted to topics in microplastics, neuroimmunotoxicity and nutraceuticals, along with a look at the latest cutting-edge technologies used to detect biomarkers. Each chapter contains several references to current literature and important resources for further reading. Given this comprehensive treatment, this book is an essential reference for anyone interested in biomarkers across the scientific and biomedical fields. Evaluates the expansive literature, providing one resource covering all aspects of toxicology biomarkers Includes completely revised chapters, along with additional chapters on the newest developments in the field Identifies and discusses the most sensitive, accurate, unique and validated biomarkers used as indicators of exposure Covers special topics and applications of biomarkers, including chapters on molecular toxicology biomarkers, biomarker analysis for nanotoxicology, development of biomarkers for drug efficacy evaluation, and much more

Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments

Examining the Use of Biomarkers in Establishing the Presence and Severity of Impairments Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services
Publisher : National Academies Press
Release : 2020-12-15
ISBN : 0309682665
Language : En, Es, Fr & De

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Book Description :

As part of the overall disability determination process, the Social Security Administration uses a step-by-step approach to understand how severe an individual's condition is and whether it meets program criteria for disability. The use of various types of biomarkers has been suggested as a way to strengthen the amount and quality of objective evidence available to the review process. At the request of the Social Security Administration, the National Academies of Sciences, Engineering, and Medicine's Board on Health Care Services organized a virtual workshop on July 21, 2020, titled The State of the Science of the Use of Biomarkers to Establish the Presence and Severity of Impairments. Workshop discussions focused on the current and potential uses for biomarkers; explored legal and ethical implications associated with biomarker use in clinical decision making; and considered the possible uses of nongenetic biomarkers as tools for the diagnosis or prognosis of the severity of specific physical and mental impairments. This publication summarizes the presentations and discussion of the workshop.

Osteoarthritis Biomarkers and Treatments

Osteoarthritis Biomarkers and Treatments Book
Author : Anonim
Publisher : BoD – Books on Demand
Release : 2019-03-27
ISBN : 1789857376
Language : En, Es, Fr & De

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Book Description :

This book presents exclusive and comprehensive insight into the detailed molecular mechanisms of osteoarthritis (OA) initiation, progression and current advancements in the field. Inputs from clinician scientists, research and expertise offer a complete explanation of the current understanding of the pathogenesis of OA and practice in imaging and treatments strategies. Contributions from leading scientists provide a detailed introduction in the use of biomarkers in clinical research as well as in clinical practice and OA diagnosis. This book further discusses the potential of regenerative therapies and recent advances in cardiovascular and functional capacity on patients with OA.

Novel Biomarkers for Heart Disease

Novel Biomarkers for Heart Disease Book
Author : Michael Lichtenauer
Publisher : MDPI
Release : 2020-12-28
ISBN : 3039438832
Language : En, Es, Fr & De

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Book Description :

Cardiac biomarkers such as troponins and natiuretic peptides have made a great impact on clinical decision making as well as improving our understanding of molecular mechanisms of different disease conditions. However, the biomarkers that are currently in use do not reflect all the multiple disease pathways that are involved in a broad spectrum of cardiac disease conditions ranging from acute coronary syndrome, to heart failure (and heart failure with preserved ejection fraction, HFpEF), to pulmonary hypertension or arrhythmias. In this Special Issue, we will provide an overview of the current developments in the field of biomarker research, beginning with research on molecular pathways and cellular communication (e.g., microRNA) up to the clinical use of biomarkers.

Orthopedic Surgery

Orthopedic Surgery Book
Author : Zaid Al-Aubaidi,Andreas Fette
Publisher : BoD – Books on Demand
Release : 2012-03-09
ISBN : 9535102311
Language : En, Es, Fr & De

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Book Description :

Orthopaedic surgery is the widest and the strongest growing surgical specialty. It is clear, that the process of improving treatments and patients care, requires knowledge, and this requires access to studies, expert opinion and books. Unfortunately, the access to this knowledge is being materialized. As we believe that access to the medical knowledge should be reachable to everyone free of charge, this book was generated to cover the orthopaedic aspect. It will provide the reader with a mix of basic, but as well highly specialized knowledge. In the process of editing this book, my wife Jurgita has been, as usual, the most supportive person. I would like to thank her for being in my life. I would like to thank Mr. Greblo, the Publishing Process Manager, for all his help and last but not least thanks to our readers, as without them this book would have no meaning.

Cancer New Insights for the Healthcare Professional 2011 Edition

Cancer  New Insights for the Healthcare Professional  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 1464900027
Language : En, Es, Fr & De

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Book Description :

Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Clinical and Imaging Assessment of Metal on Metal Hip Patients

Clinical and Imaging Assessment of Metal on Metal Hip Patients Book
Author : Reshid Berber
Publisher : Unknown
Release : 2019
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

A high failure rate of metal-on-metal (MoM) hip implants prompted regulatory authorities to issue worldwide product recalls. The cause for their failure and decisions surrounding the need for revision is complex due to poor understanding of the toxic effects of metal debris. In addition to local soft tissue destruction, circulating cobalt can cause rare but fatal cardiotoxicity. This thesis describes the detection of metal cobalt-chromium within the liver of a patient with highly elevated blood cobalt (587ppb) using novel MRI imaging techniques, validated by liver biopsy and micro x-ray fluorescence. The prevalence of tissue metal deposition and potential cardiotoxic effects were assessed through a prospective case controlled cohort study. Ninety patients were recruited into three age and gender-matched groups according to blood metal levels. All underwent detailed cardiovascular and liver phenotyping using MRI (for myocardial volumes and function, T2*, T1 and Extra-Cellular Volume mapping), echocardiography, and blood biomarker sampling. T2* is a novel MRI biomarker of tissue metal deposition. Blood cobalt levels among the cohort ranged 0.1 to 118ppb, which is still seen in patients presenting for clinical follow-up. No significant between-group differences were found for cardiac volume or function, nor was there any difference in tissue characterization using T1, T2* and ECV. Higher blood cobalt levels did not translate to increased metal deposition within the heart or liver.The application of these results were analsyed through a multi-disciplianary team setting designed to aid complex decisions of who, when and how to treat MoM patients surgically. By analysis of MDT recommendations compared to the treatment undertaken it was demonstrated that an MDT approach is an acceptable evidence-based aid to decision-making.This thesis concludes that cobalt tissue deposition can be detected using non-invasive MRI techniques, however metal deposition is not commonly seen with blood cobalt levels upto 118ppb with reassuringly little cardiotoxic effects. These results help reassure clinicians managing MoM patients through an MDT approach.

Obesity New Insights for the Healthcare Professional 2013 Edition

Obesity  New Insights for the Healthcare Professional  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-07-22
ISBN : 1481654721
Language : En, Es, Fr & De

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Book Description :

Obesity: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Diagnosis and Screening. The editors have built Obesity: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Diagnosis and Screening in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Obesity: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Cartilage Injury of the Knee

Cartilage Injury of the Knee Book
Author : Aaron J. Krych
Publisher : Springer Nature
Release : 2021-09-25
ISBN : 3030780511
Language : En, Es, Fr & De

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Book Description :

Download Cartilage Injury of the Knee book written by Aaron J. Krych, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Issues in Rheumatology Research and Practice 2011 Edition

Issues in Rheumatology Research and Practice  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 146496615X
Language : En, Es, Fr & De

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Book Description :

Issues in Rheumatology Research and Practice: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Rheumatology Research and Practice. The editors have built Issues in Rheumatology Research and Practice: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Rheumatology Research and Practice in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Rheumatology Research and Practice: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Principles of Translational Science in Medicine

Principles of Translational Science in Medicine Book
Author : Martin Wehling
Publisher : Academic Press
Release : 2021-07-15
ISBN : 032399962X
Language : En, Es, Fr & De

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Book Description :

Principles of Translational Science in Medicine: From Bench to Bedside, Third Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing number of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. New chapters include: Translation in Oncology, Biologicals, and Orphan Drugs. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine and is written by worldwide experts in their respective fields. Includes state-of-the-art principles, tools such as biomarkers and early clinical trials, algorithms of translational science in medicine Provides in-depth description of special translational aspects in the currently most successful areas of clinical translation, namely oncology and immunology Covers status of institutionalization of translational medicine, networking structures and outcomes at the level of marketing authorization

Osteoarthritis

Osteoarthritis Book
Author : Mohit Kapoor,Nizar N. Mahomed
Publisher : Springer
Release : 2015-07-20
ISBN : 3319195603
Language : En, Es, Fr & De

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Book Description :

This comprehensive book grants readers exclusive insight into current advancements in the field of osteoarthritis (OA). Contributions from leading scientists and clinicians provide a detailed introduction into current understanding of the pathogenesis of OA, different joint structures affected by this debilitating disease (hip, knee, elbow, shoulder, foot, ankle, hand, wrist, and spine), current knowledge and practice in imaging, joint conservative strategies, OA biomarkers as well as currently available treatments, their safety profile and future therapeutic targets. This book further discusses the potential of regenerative therapies and recent advances in OA Personalized Medicine, and how collection of OA patient’s phenotypic, genetic and proteomic data is able to direct treatment strategies through Bio-Informatics.

Orthopedic Management of the Hip and Pelvis

Orthopedic Management of the Hip and Pelvis Book
Author : Scott W. Cheatham,Morey J. Kolber
Publisher : Elsevier Health Sciences
Release : 2016-01-01
ISBN : 0323294383
Language : En, Es, Fr & De

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Book Description :

The first book to focus solely on disorders of the hip and pelvis region, this physical therapy text offers evidence-based information on the care of non-surgical and surgical patients with common pathologies and injuries. Comprehensive guidelines cover a wide range of topics, from anatomy and assessment to strains, tears, and disorders that affect groups such as females, children, dancers, and patients with arthritis.

Handbook of Clinical Anaesthesia 3E

Handbook of Clinical Anaesthesia 3E Book
Author : Brian Pollard
Publisher : CRC Press
Release : 2011-08-26
ISBN : 144410862X
Language : En, Es, Fr & De

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Book Description :

The Handbook of Clinical Anaesthesia has been completely updated for this new edition, providing trainee anaesthetists with a concise but comprehensive source of clinical information, and qualified anaesthetists with an indispensable aide. Written and edited by experts in the field, this compact but detailed text provides all the essential practical knowledge required by anaesthetists on co-existing medical conditions, operative procedures, and techniques. The handbook is presented in Parts 1 to 3. The first part covers Patient Conditions; the second part Surgical Procedures; and the third part Anaesthetic Factors. Each part is subdivided into sections on each organ system, and each section is divided into chapters. These chapters are in alphabetical order, and cover all common and rare conditions that anaesthetists will encounter within their practice.Trainees will find this book to be an excellent general guide, but in particular a provider of reliable information in preparation for examination as well as teaching clinical technique and practice.

Index Medicus

Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biomaterials Science

Biomaterials Science Book
Author : William R Wagner,Shelly E. Sakiyama-Elbert,Guigen Zhang,Michael J. Yaszemski
Publisher : Academic Press
Release : 2020-05-23
ISBN : 0128161388
Language : En, Es, Fr & De

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Book Description :

The revised edition of the renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science from principles to applications. Biomaterials Science, fourth edition, provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine. This new edition incorporates key updates to reflect the latest relevant research in the field, particularly in the applications section, which includes the latest in topics such as nanotechnology, robotic implantation, and biomaterials utilized in cancer research detection and therapy. Other additions include regenerative engineering, 3D printing, personalized medicine and organs on a chip. Translation from the lab to commercial products is emphasized with new content dedicated to medical device development, global issues related to translation, and issues of quality assurance and reimbursement. In response to customer feedback, the new edition also features consolidation of redundant material to ensure clarity and focus. Biomaterials Science, 4th edition is an important update to the best-selling text, vital to the biomaterials’ community. The most comprehensive coverage of principles and applications of all classes of biomaterials Edited and contributed by the best-known figures in the biomaterials field today; fully endorsed and supported by the Society for Biomaterials Fully revised and updated to address issues of translation, nanotechnology, additive manufacturing, organs on chip, precision medicine and much more. Online chapter exercises available for each chapter

Surgery of the Hip E Book

Surgery of the Hip E Book Book
Author : Daniel J. Berry,Jay Lieberman
Publisher : Elsevier Health Sciences
Release : 2019-09-24
ISBN : 0323568416
Language : En, Es, Fr & De

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Book Description :

Offering authoritative, comprehensive coverage of hip surgery, the 2nd Edition of Surgery of the Hip is the definitive guide to hip replacement, other open and arthroscopic surgical procedures, and surgical and nonsurgical management of the hip across the lifespan. Modeled after Insall & Scott Surgery of the Knee, it keeps you fully up to date with the latest research, techniques, tools, and implants, enabling you to offer both adults and children the best possible outcomes. Detailed guidance from expert surgeons assists you with your toughest clinical challenges, including total hip arthroplasty, pediatric hip surgery, trauma, and hip tumor surgery. Discusses new topics such as direct anterior approach for total hip arthroplasty, hip pain in the young adult, and hip preservation surgery. Contains new coverage of minimally invasive procedures, bearing surface selection, management of complications associated with metal and metal bearing surfaces, management of bone loss associated with revision THA, and more. Provides expert, personal advice in "Author’s Preferred Technique" sections. Helps you make optimal use of the latest imaging techniques, surgical procedures, equipment, and implants available. Covers tumors of the hip, hip instability and displacement in infants and young children, traumatic injuries, degenerative joint disorders, and rehabilitation considerations—all from both a basic science and practical clinical perspective.