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Biomarkers In Bipolar Disorders

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Biomarkers in Bipolar Disorders

Biomarkers in Bipolar Disorders Book
Author : Rodrigo Machado-Vieira,Jair Soares
Publisher : Academic Press
Release : 2021-10-15
ISBN : 9780128213988
Language : En, Es, Fr & De

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Book Description :

Nearly 5.7 million adult Americans are affected by bipolar disorder according to the National Institute of Mental Health. Bipolar disorder (BD) is a recurrent chronic disorder characterized by fluctuations in mood. Those suffering from bipolar disorder are at crossroads, suffering a major personal, social and economic burden. Currently, there lacks of definitive diagnostic tools for psychiatric disorders. Psychiatry continues to rely on a non-biologically based, diagnostic classification. Identification of biologically relevant markers could improve the quality of life of patients with bipolar disorder and revolutionize public health. Biomarkers in Bipolar Disorders summarizes the cutting-edge findings in biomarkers research in Bipolar Disorders, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings emphasizing different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes with as well as the most promising perspectives in each area are included in the book. Each section includes a comprehensive and focused overview on the state of the art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder. Describes strategies for biomarker discovery of relevant proteins differentially expressed in Bipolar Disorder Presents techniques and main findings in transcriptome research related to CNS synaptic function Provides an overview on the current behavioral strategies and their validity in drug development in Bipolar Disorder Discusses current genetic findings integrating tests for treatments leading to personalized treatments in the management of Bipolar Disorder

Novel Biomarkers for Bipolar Disorder

Novel Biomarkers for Bipolar Disorder Book
Author : Anonim
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Novel Biomarkers for Bipolar Disorder book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Bipolar Disorder

Bipolar Disorder Book
Author : Strakowski Stephen M
Publisher : Oxford University Press, USA
Release : 2020
ISBN : 0190908092
Language : En, Es, Fr & De

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Book Description :

"Bipolar disorders are among the more common conditions affecting humankind and are, consequently, leading causes of disability worldwide. These illnesses are dynamic and complex, so that identifying them and then provide optimal management can be challenging. Because of this complexity, these conditions often comprise a disproportionate amount of most psychiatric practices, as specialty care that exceeds what can be delivered by other practitioners is often required. With these challenges in mind, we created this book to provide a comprehensive, readable review of these illnesses with chapters written by international experts in bipolar disorder"--

Biomarkers in Psychiatry

Biomarkers in Psychiatry Book
Author : Judith Pratt,Jeremy Hall
Publisher : Springer
Release : 2019-01-05
ISBN : 3319996428
Language : En, Es, Fr & De

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Book Description :

This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.

Biomarkers of Postpartum Psychiatric Disorders

Biomarkers of Postpartum Psychiatric Disorders Book
Author : Jennifer L. Payne,Lauren M. Osborne
Publisher : Academic Press
Release : 2019-09-28
ISBN : 0128158360
Language : En, Es, Fr & De

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Book Description :

Biomarkers of Postpartum Psychiatric Disorders provides an up-to-date reference on the current research relating to biomarkers in psychiatric disorders, including major depressive disorder, OCD and bipolar disorder in the immediate postpartum time-period. It is the only reference on the market that synthesizes and interprets available data and reviews clinical phenotypes. Topics cover hormonal contributions, immunology, epigenetics and neuroimaging. While the risk of psychiatric illness during pregnancy appears to be equivalent to the risk at any other time in a woman’s life, the risk in the immediate postpartum time period is dramatically increased, hence the importance of the discussions in this title. Identifies epigenetic, hormonal, immunological and neuroimaging biomarkers Provides biomarkers for depression, OCD and psychosis Includes clinical phenotypes for psychiatric disorders Discusses future research and directions in the field

Neuroprogression and Staging in Bipolar Disorder

Neuroprogression and Staging in Bipolar Disorder Book
Author : Flávio Kapczinski,Eduard Vieta,Pedro V. S. Magalhães,Michael Berk
Publisher : Oxford University Press, USA
Release : 2015
ISBN : 0198709994
Language : En, Es, Fr & De

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Book Description :

Provides a solid and in-depth outline that can be used to influence research and practice in the field of bipolar disorder. This book would be of use to anyone working with mood disorders, and serves as a valuable resource for both researchers interested in bipolar disorder and clinicians involved in the day-to-day management of patientswithh this condition.--

New Oxford Textbook of Psychiatry

New Oxford Textbook of Psychiatry Book
Author : John R. Geddes,Nancy C. Andreasen
Publisher : Oxford University Press, USA
Release : 2020-02-20
ISBN : 0198713002
Language : En, Es, Fr & De

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Book Description :

Over its two editions, The New Oxford Textbook of Psychiatry has come to be regarded as one of the most popular and trusted standard psychiatry texts among psychiatrists and trainees. Bringing together 146 chapters from the leading figures in the discipline, it presents a comprehensive account of clinical psychiatry, with reference to its scientific basis and to the patient's perspective throughout. The New Oxford Textbook of Psychiatry, Third Edition has been extensively re-structured and streamlined to keep pace with the significant developments that have taken place in the fields of clinical psychiatry and neuroscience since publication of the second edition in 2009. The new edition has been updated throughout to include the most recent versions of the two main classification systems---the DSM-5 and the ICD-11---used throughout the world for the diagnosis of mental disorders. In the years since publication of the first edition, many new and exciting discoveries have occurred in the biological sciences, which are having a major impact on how we study and practise psychiatry. In addition, psychiatry has fostered closer ties with philosophy, and these are leading to healthy discussions about how we should diagnose and treat mental illness. This new edition recognises these and other developments. Throughout, accounts of clinical practice are linked to the underlying science, and to the evidence for the efficacy of treatments. Physical and psychological treatments, including psychodynamic approaches, are covered in depth. The history of psychiatry, ethics, public health aspects, and public attitudes to psychiatry and to patients are all given due attention.

Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals

Proteomic and Ionomic Study for Identification of Biomarkers in Biological Fluid Samples of Patients with Psychiatric Disorders and Healthy Individuals Book
Author : Jemmyson Romário de Jesus
Publisher : Springer Nature
Release : 2019-10-22
ISBN : 3030294730
Language : En, Es, Fr & De

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Book Description :

This book presents an exploratory analysis based on proteomic and ionomics studies comparing the blood serum of patients with bipolar disorder (BD), healthy controls, patients with schizophrenia (SCZ), and patients with other disorders (OD) in order to identify biomarkers of BD. Bipolar disorder is a psychiatric condition that affects thousands of people worldwide. The absence of biomarkers for BD has resulted in misdiagnosis and ineffective treatment in some patients, causing additional health problems and high costs for health systems. As such, this book evaluates various strategies for sample preparation for proteomic and ionomic studies in order to simplify complex serum samples and allow the quantification of chemical species (proteins and metal ions), which are potential candidates for BD biomarkers. In addition, it describes the development of a new membrane-based methodology for extracting urine proteins to be used in biomarker discovery.

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders Book
Author : Paul C. Guest
Publisher : Springer
Release : 2019-02-12
ISBN : 3030055426
Language : En, Es, Fr & De

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Book Description :

This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.

Oxford Textbook of Neuropsychiatry

Oxford Textbook of Neuropsychiatry Book
Author : Niruj Agrawal,Rafey Faruqui,Mayur Bodani
Publisher : Oxford University Press, USA
Release : 2020-08-24
ISBN : 0198757131
Language : En, Es, Fr & De

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Book Description :

New from Oxford Textbooks in Psychiatry, the Oxford Textbook of Neuropsychiatry bridges the gap between general psychiatric textbooks and reference texts in neuropsychiatry. Divided into four sections, it covers core knowledge and skills for practice in all psychiatric disciplines, with key information for training in neuropsychiatry.

Index Medicus

Index Medicus Book
Author : Anonim
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Index Medicus book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Overdiagnosis in Psychiatry

Overdiagnosis in Psychiatry Book
Author : Joel Paris
Publisher : Oxford University Press, USA
Release : 2015
ISBN : 0199350647
Language : En, Es, Fr & De

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Book Description :

Dr. Joel Paris's Overdiagnosis in Psychiatry takes a much-needed look at the dangerous epidemic of unnecessary or incorrect treatments. The last 30 years of psychiatry have seen the development of a system of classification aimed at establishing greater scientific credibility. Unfortunately, the current categories are based entirely on signs and symptoms rather than on causes, which remain unknown. This has inevitably made diagnosis imprecise and uncertain. The result is that well-meaning professionals can have problems separating psychopathology from normality, can be unduly influenced by diagnostic fads, and can ultimately wind up prescribing treatments that do more harm than good. Paris examines prominent examples of overused diagnoses including major depressive disorder, ADHD, bipolar-II disorder, autism spectrum disorders, and PTSD.

Immunopsychiatry

Immunopsychiatry Book
Author : Antonio L. Teixeira,Moises E. Bauer
Publisher : Oxford University Press, USA
Release : 2019-01-18
ISBN : 0190884460
Language : En, Es, Fr & De

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Book Description :

In recent years, a dedicated effort has been made to understand the immune dysfunction that is associated with major psychiatric disorders. The expanding knowledge of the immune system as a major homeostatic system has been very helpful in indicating new potential biomarkers and therapeutic targets to reduce the burden of psychiatric disorders. Indeed, immune cells, their secreted molecules, and cell signalling events are highly promising. Yet, the literature on immunology of psychiatric disorders is still dispersed, and only a few attempts have been made to consolidate the current knowledge in this expanding area. This book assembles and presents the available data on the immune/inflammatory dysfunction in psychiatric disorders, indicating the potential of immune mechanisms as either biomarkers or therapeutic targets, as well as discussing the challenges ahead of incorporating this knowledge into clinical practice. An international team of senior experts in the field review all psychiatric disorders in order to provide an integrated, in-depth understanding of the role of immune changes in psychiatric diseases for mental health clinicians as well as for researchers in immunology, psychiatry, neurology, and pharmacology.

Biological Markers in Psychiatry and Neurology

Biological Markers in Psychiatry and Neurology Book
Author : Earl Usdin,Israel Hanin
Publisher : Pergamon
Release : 1982
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Biological Markers in Psychiatry and Neurology is a collection of papers that details the advancement in the understanding of the biological markers that stems from psychiatric and neurological pathologies. The text first covers topics about various biological markers, such as neurochemical, enzymatic, membrane, receptors, endocrine, and physiological. Next, the selection examines the relationship between alcohol abuse and biological papers. The next part covers the genetic aspects of biological markers. The text also deals with use of tomography and modeling theory. The book will be of great ...

Oxford Textbook of Old Age Psychiatry

Oxford Textbook of Old Age Psychiatry Book
Author : Tom Dening,Alan Thomas,John Paul Taylor,Robert Stewart
Publisher : Oxford University Press, USA
Release : 2020-11-05
ISBN : 0198807295
Language : En, Es, Fr & De

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Book Description :

Part of the authoritative Oxford Textbooks in Psychiatry series, Oxford Textbook of Old Age Psychiatry, Third Edition has been thoroughly updated to reflect the developments in old age psychiatry since publication of the Second Edition in 2013, and remains an essential reference for anyone interested in the mental health care of older people.

Biomarkers of Neurological and Psychiatric Disease

Biomarkers of Neurological and Psychiatric Disease Book
Author : Sabine Bahn,Paul Guest
Publisher : Academic Press
Release : 2011-11-23
ISBN : 0123877180
Language : En, Es, Fr & De

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Book Description :

Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding the movement disorder Dyskinesia. Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Proteomics and Metabolomics in Psychiatry

Proteomics and Metabolomics in Psychiatry Book
Author : D. Martins-de-Souza
Publisher : Karger Medical and Scientific Publishers
Release : 2014-05-23
ISBN : 331802600X
Language : En, Es, Fr & De

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Book Description :

This publication compiles data generated by proteomics and metabolomics about psychiatric disorders. Leading researchers in these fields review the basic principles of proteomics and metabolomics and propose the new directions to be followed in molecular psychiatry. The chapters divided into two sections – Schizophrenia/Psychotic Disorders and Mood Disorders – deal with findings in diverse tissues from human and preclinical models in order to unravel the biology and biochemistry behind the establishment and course of these illnesses as well as potential biomarkers for clinical applications. More than an update, this publication indicates the next steps to discover biomarkers and understand psychiatric disorders more comprehensively. This publication is valuable reading for psychiatrists, neuroscientists and analytical chemists interested in the basics of proteomics and metabolomics, psychiatric definitions and the most advanced hypotheses about the pathobiology of schizophrenia, depression and bipolar disorder.

Comprehensive medicinal chemistry II

Comprehensive medicinal chemistry II Book
Author : John B. Taylor,D. J. Triggle
Publisher : Elsevier Science Ltd
Release : 2007
ISBN : 9780080445137
Language : En, Es, Fr & De

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Book Description :

The first edition of Comprehensive Medicinal Chemistry was published in 1990 and very well received. Comprehensive Medicinal Chemistry II is much more than a simple updating of the contents of the first edition. Completely revised and expanded, this new edition has been refocused to reflect the significant developments and changes over the past decade in genomics, proteomics, bioinformatics, combinatorial chemistry, high-throughput screening and pharmacology, and more. The content comprises the most up-to-date, authoritative and comprehensive reference text on contemporary medicinal chemistry and drug research, covering major therapeutic classes and targets, research strategy and organisation, high-throughput technologies, computer-assisted design, ADME and selected case histories. It is this coverage of the strategy, technologies, principles and applications of medicinal chemistry in a single work that will make Comprehensive Medicinal Chemistry II a unique work of reference and a single point of entry to the literature for pharmaceutical and biotechnology scientists of all disciplines and for many industry executives as well.Comprehensive Medicinal Chemistry II will be available online in 2007 via the proven platform ScienceDirect providing the user with enhanced features such as cross-referencing and dynamic linking. * Comprehensively reviews - for the first time in one single work - the strategies, technologies, principles and applications of modern medicinal chemistry * Provides a global and current perspective of today's drug discovery process and discusses the major therapeutic classes and targets * Includes a unique collection of case studies and personal assays reviewing the discovery and development of key drugs

Bipolar Disorder

Bipolar Disorder Book
Author : Nickolas B. Moore
Publisher : Nova Science Pub Incorporated
Release : 2013-01-01
ISBN : 9781626186668
Language : En, Es, Fr & De

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Book Description :

Bipolar disorder is a psychiatric disease that involves profound changes in mood accompanied by severe changes in feelings, thoughts and behaviors wherein emotions can move quickly from a deep depression to excessive excitement without apparent reason. In this book, the authors present current research in the study of the symptoms, management and risk factors of bipolar disorder. Topics include face emotion processing deficits in pediatric bipolar disorder; understanding bipolar disorder from clinical expression to therapeutic strategies; brain-derived neurotrophic factors and neurocognitive profiles in the psychosis spectrum; understanding lived experience and personal recovery in people with bipolar disorder; computerized self-management in bipolar disorder; prescription drug Memantine in the long-term prophylaxis of treatment-resistant bipolar mood disorders; P11 expression and PET as potential biomarkers for bipolar disorder; and neurocognitive impairment in bipolar disorder.

Neuroscience Biomarkers and Biosignatures

Neuroscience Biomarkers and Biosignatures Book
Author : Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publisher : National Academies Press
Release : 2008-01-08
ISBN : 9780309178280
Language : En, Es, Fr & De

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Book Description :

Biomarkers, or biological markers, are quantitative measurements that offer researchers and clinicians valuable insight into diagnosis, treatment and prognosis for many disorders and diseases. A major goal in neuroscience medical research is establishing biomarkers for disorders of the nervous system. Given the promising potential and necessity for neuroscience biomarkers, the Institute of Medicine Forum on Neuroscience and Nervous System Disorders convened a public workshop and released the workshop summary entitled Neuroscience Biomarkers and Biosignatures: Converging Technologies, Emerging Partnerships. The workshop brought together experts from multiple areas to discuss the most promising and practical arenas in neuroscience in which biomarkers will have the greatest impact. The main objective of the workshop was to identify and discuss biomarker targets that are not currently being aggressively pursued but that could have the greatest near-term impact on the rate at which new treatments are brought forward for psychiatric and neurological disorders.