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Biofilms In Infection Prevention And Control

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Biofilms in Infection Prevention and Control

Biofilms in Infection Prevention and Control Book
Author : Steven L. Percival,David Williams,Jacqueline Randle,Tracey Cooper
Publisher : Academic Press
Release : 2014-02-26
ISBN : 9780123970435
Language : En, Es, Fr & De

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Book Description :

Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds. Provides specific procedures for controlling and preventing infection Includes case studies of HCAI, and identifies appropriate treatments Presents national government standards for infection prevention and control Includes extensive references and links to websites for further information

Device Associated Infections An Issue of Infectious Disease Clinics of North America

Device Associated Infections  An Issue of Infectious Disease Clinics of North America Book
Author : Vivian H Chu
Publisher : Elsevier Health Sciences
Release : 2018-11-06
ISBN : 0323653626
Language : En, Es, Fr & De

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Book Description :

In collaboration with Consulting Editor, Dr. Helen Boucher, Dr. Vivian Chu has created an issue that provides current clinical updates on device-associated infections. Authors are represented by experts across the world, who have contributed clinical reviews on the following topics: Intravascular Catheter-Related Bloodstream Infections; Vascular Graft Infections; Cardiovascular Implantable Electronic Device-Associated Infections; Left Ventricular Device-Associated Infections; Urinary Catheter-Associated Infections; Prosthetic Joint Infections; Neurosurgical Device-Related Infections; Breast Implant Infections; Cochlear Implant Infections; Gastrointestinal Scope-Related Infections; Understanding Biofilms and Novel Approaches to the Diagnosis, Prevention, and Treatment of Medical Device-Associated infections; and Infections of Hemodialysis Access Devices. Readers will come away with the information they need to make informed clinical decisions that improve patient outcomes.

Hygienically Relevant Biofilms

Hygienically Relevant Biofilms Book
Author : Rok Fink
Publisher : Nova Science Pub Incorporated
Release : 2015-01-01
ISBN : 9781634633161
Language : En, Es, Fr & De

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Book Description :

This book describes biofilms in the context of hygiene in food safety and hospital facilities, starting with bacterial adhesion as an initial step of cell colonization, followed by the growth and maturation of biofilms. The main focus of this book is on biofilm prevention and control. The resistance of bacteria to several antibiotics is a global public health problem, not limited to hospital facilities, but also to other sectors, including the food industry. This raises questions about whether effective cleaning and disinfection reduce the risk of food-borne and hospital-acquired illness. Can the surface characteristics be treated to prevent bacterial adhesion and, consequently, the formation of biofilms? Biofilms are complex communities of bacteria attached the surfaces, with fully developed architecture and highly organized interactions. A better understanding of the biofilm lifecycle, with advanced strategies of physical, chemical and biological actions, would reduce the risk of infection. The question is not whether the preventive and control measures will play a significant role in public health, but rather what the implications of their use will be for hygiene in the food industry and hospital facilities.

Infection Prevention and Control Guide for Health Care Professionals

Infection Prevention and Control Guide for Health Care Professionals Book
Author : Jim Ayukekbong
Publisher : Lulu.com
Release : 2019-08-24
ISBN : 0359843751
Language : En, Es, Fr & De

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Book Description :

Are you a health care professional or someone interested in disease control? If yes, then, this book is for you. The author provides a simplistic guide on how to prevent and control the spread of infections in both health care and non-health care environments. The book represents a handy tool for quality patient care and infection control best practices.

Manual of Infection Prevention and Control

Manual of Infection Prevention and Control Book
Author : Nizam Damani
Publisher : OUP Oxford
Release : 2011-12-22
ISBN : 0191628638
Language : En, Es, Fr & De

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Book Description :

It has been estimated that in developed countries up to 10% of hospitalized patients develop infections every year. Not only is there a substantial cost to healthcare systems, but some healthcare associated infections (HCAIs) can be fatal. Since the majority of HCAIs are preventable, reducing HCIAs is now considered to be an integral part of patient safety and quality of care provided by all healthcare institutions worldwide. Unlike other books on infection control, the main strength of this book is to provide clear, up-to-date and practical guidance in infection control in an easy to read format which can act as a quick source of reference on all aspects of HCAIs for healthcare workers who are either directly or indirectly involved in prevention and control of HCAIs. Although the book's main audience is infection control practitioners such as doctors, nurses, public health physicians, it is also a valuable reference for environmental health officers, health educators, practice managers in GP surgeries, and health service managers.

Hospital Acquired Infections Prevention Control Prevention and Control

Hospital Acquired Infections  Prevention   Control  Prevention and Control Book
Author : Purva Mathur
Publisher : Wolters kluwer india Pvt Ltd
Release : 2010-01-01
ISBN : 8184731973
Language : En, Es, Fr & De

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Book Description :

The spread of infections associated with hospitals and clinics has increased dramatically in recent years and their prevention constitutes a major challenge for healthcare personnel. This book highlights the growing threat from hospital acquired infections and thoroughly explains the relevant measures for their prevention. Measures for control are also succinctly presented. The book also focuses on local epidemiology relating to the spread of these infections in India and highlights appropriate measures for their prevention. The text is presented in a clear and crisp style and important features and procedures are adequately highlighted in relevant boxes, tables and flowcharts. Physicians, surgeons and microbiologists would find this book to be extremely useful. Laboratory personnel and nursing staff would also benefit considerably from this book.

Biofilms and Implantable Medical Devices

Biofilms and Implantable Medical Devices Book
Author : Ying Deng,Wei Lv
Publisher : Woodhead Publishing
Release : 2016-10-24
ISBN : 0081003986
Language : En, Es, Fr & De

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Book Description :

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

Basic Guide to Infection Prevention and Control in Dentistry

Basic Guide to Infection Prevention and Control in Dentistry Book
Author : Caroline L. Pankhurst,Wilson A. Coulter
Publisher : John Wiley & Sons
Release : 2013-05-08
ISBN : 1118708199
Language : En, Es, Fr & De

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Book Description :

The Basic Guide to Infection Prevention and Control inDentistry is a practical guide for all members of the dentalteam. It offers clear explanations of the key issues and concepts,an orientation of the evidence base and legal framework as well asproviding a step-by-step guide to the safe running of a dentalpractice. Chapters cover key topics, namely: communicable diseases;occupational health and immunisation; decontamination of dentalequipment; surgery disinfect ion; sharp safe working; hand hygieneand barrier personal protection; dental unit waterlines, clinicalwaste management and pathology specimen handling.

Biofilm Eradication and Prevention

Biofilm Eradication and Prevention Book
Author : Tamilvanan Shunmugaperumal
Publisher : John Wiley & Sons
Release : 2010-12-28
ISBN : 9781118043554
Language : En, Es, Fr & De

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Book Description :

Biofilm Eradication and Preventions presents the basics of biofilm formation on medical devices, diseases related to this formation, and approaches pharmaceutical researchers need to take to limit this problem. Split into three parts, the first deals with the development and characterization of biofilm on the surfaces of implanted or inserted medical devices. Questions as to why biofilms form over medical device surfaces and what triggers biofilm formation are addressed. In the second section, the author discusses biofilm-mediated chronic infections occurred in various organs (eyes, mouth, wounds) and pharmaceutical and drug delivery knowledge gained from research in these area. The third part explores pharmaceutical approaches like lipid-and polymer-based drug delivery carriers for eradicating biofilm on device-related infections. In addition, this section also explores the topic of novel small molecule (like iron and its complexes/metal chelators) and a quorum-sensing inhibitors to control medical biofilm formation.

Infection Prevention and Control at a Glance

Infection Prevention and Control at a Glance Book
Author : Debbie Weston,Alison Burgess,Sue Roberts
Publisher : John Wiley & Sons
Release : 2016-11-30
ISBN : 1118973550
Language : En, Es, Fr & De

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Book Description :

Infection Prevention and Control at a Glance is the perfect companion for study and revision for pre-registration nursing and healthcare students, as well as qualified nurses and medical students. Infection prevention and control is one of the key five ‘essential skills clusters’ that is incorporated into all pre-registration nursing programmes. This highly visual and dynamic book is a thorough resource for nurses wanting to consolidate and expand their knowledge of this important part of nursing. Written by experienced infection prevention and control specialist nurses, it provides a concise and simple approach to a vast and complex subject, and equips the reader with key information in relation to various aspects of infection prevention and control practice. Provides a snap-shot of the application of infection prevention and control in practice and the key infections affecting patients in both acute and primary care A uniquely visual and accessible overview of a topic of relevance to all nursing staff Includes key points for clinical practice, patient management, and signposting of key national guidance documents and websites Available in a wide-range of digital formats - perfect for 'on the go' study and revision

Medical Biofilms

Medical Biofilms Book
Author : Jana Jass,Susanne Surman,James Walker
Publisher : John Wiley & Sons
Release : 2003-04-02
ISBN : 9780471988670
Language : En, Es, Fr & De

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Book Description :

Biofilms are formed by microorganisms growing on surfaces and comprise a series of microcolonies interspersed with spaces through which fluids and other microorganisms move. In medicine, the primary problems are biofilms associated with implants: infections are increasingly difficult to treat with traditional antibiotics and removal of the implant often becomes essential, frequently leading to higher morbidity and mortality. This will be the first book dedicated to medical biofilms. It will cover much recent information on the problems of biofilms, how to detect them and how to control their presence.

Biofilms in Human Diseases Treatment and Control

Biofilms in Human Diseases  Treatment and Control Book
Author : Sunil Kumar,Niharika Chandra,Leena Singh,Muhammad Zaffar Hashmi,Ajit Varma
Publisher : Springer Nature
Release : 2019-11-19
ISBN : 3030307573
Language : En, Es, Fr & De

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Book Description :

This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm formation and its mechanism. Topics covered include biofilms in human health, the role of biofilms in mediating human diseases, and methods for testing bacterial biofilms. Further sections concentrate on biofilm-mediated diseases in different parts of the human gastrointestinal tract, while therapeutic strategies for biofilm control and natural agents that disrupt bacterial biofilms are also covered. Readers will also find the latest advances in probiotics and biofilms, as well as the use of probiotics to counteract biofilm-associated infections. Biofilms and antimicrobial resistance are discussed. Subsequent chapters address the management of inflammatory bowel disease via probiotics biofilms, as well as the role of probiotics bacteria in the treatment of human diseases associated with bacterial biofilms. The book is chiefly intended for clinicians/scientists in the fields of medical microbiology, applied microbiology, biochemistry, and biotechnology.

Topical Antimicrobials Testing and Evaluation Second Edition

Topical Antimicrobials Testing and Evaluation  Second Edition Book
Author : Daryl S. Paulson
Publisher : CRC Press
Release : 2014-12-20
ISBN : 143981323X
Language : En, Es, Fr & De

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Book Description :

A range of factors must be considered when developing a topical antimicrobial for use in a healthcare personnel handwash, surgical scrub, or preoperative skin preparation. Antimicrobial effectiveness, low skin irritation, ease of use, and pleasing aesthetics are all essential if the product is to succeed. In addition, all facets of the product must comply with stringent regulatory requirements. With updated protocols and research, Topical Antimicrobials Testing and Evaluation, Second Edition comprehensively presents and reviews the latest techniques for testing antimicrobial compounds for effectiveness and regulatory compliance. Topics include: The anatomical structure of the skin and skin microbiology relevant to product testing Use of antimicrobial products against specific microorganisms such as Staphylococcus and Streptococcus species Measurement of antimicrobial action of topical antimicrobials from experimental design, microbiological, biostatistical, and marketplace perspectives Various aspects of the topical antimicrobial products currently in common use in medical, food service, and consumer markets Statistical analysis and specific statistical designs for clinical trials Epistemological requirements in evaluating the effects of specific treatments Evaluation strategies and sample working protocols for hand and body soaps, food-handler antimicrobial products, and medical/healthcare industry antimicrobial products The book is designed to inform industry and academia on the requirements to get products approved by the FDA and to market while also providing critical insight on ways to best service expanding markets.

Infection Prevention and Control in Healthcare Part I Facility Planning and Management An Issue of Infectious Disease Clinics of North America E Book

Infection Prevention and Control in Healthcare  Part I  Facility Planning and Management  An Issue of Infectious Disease Clinics of North America  E Book Book
Author : Keith S. Kaye,Sorabh Dhar
Publisher : Elsevier Health Sciences
Release : 2016-08-16
ISBN : 0323462790
Language : En, Es, Fr & De

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Book Description :

Dr. Kaye and Dr. Dhor have assembled top experts to write about facility planning and management in Part I of their two issues devoted to Infection Prevention and Control in Healthcare. Articles in this issue are devoted to: Building a Successful Infection Control Program: Key Components, Processes and Economics; Hand Hygiene Sterilization; High Level Disinfection and Environmental Cleaning; Environement of Care; Infection Control in Alternative Healthcare Settings (Long Term Care and Ambulatory); Antibiotic Stewardship; Outbreak Investigations Water Safety in Healthcare/Legionella in the Healthcare Setting; Construction and Renovation; Bloodborne and Body Fluid Exposures - prevention and management of Occupational Health Issues; and Informatics and Statistics in Infection Control. Part II is devoted to clinical management of infections.

Infection Prevention and Control in Healthcare Part II Epidemiology and Prevention of Infections An Issue of Infectious Disease Clinics of North America

Infection Prevention and Control in Healthcare  Part II  Epidemiology and Prevention of Infections  An Issue of Infectious Disease Clinics of North America  Book
Author : Keith S. Kaye,Sorabh Dhar
Publisher : Elsevier Health Sciences
Release : 2016-11-07
ISBN : 0323477631
Language : En, Es, Fr & De

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Book Description :

Dr. Kaye and Dr. Dhor have assembled top experts to write about clinical management of infections in Part II of their two issues devoted to Infection Prevention and Control in Healthcare. Articles in this issue are devoted to: CLABSI; UTI; Tuberculosis; Ventilator-Assisted Pneumonia; Surgical Site Infection; MRSA; VRE; Gram-Negative Bacilli; Fungal Infections; C. Difficile, and Emerging Infections including Ebola. Infectious Disease physicians and anyone in the hospital setting will find this issue very useful, as state-of-the-art clinical reviews provide clinical management on these common and emerging infections.

Assessment Of The Ability Of Stimulan Beads To Release A Combination Of Antibiotics To Effectively Eradicate Pre Formed Biofilms In Vitro

Assessment Of The Ability Of Stimulan   Beads To Release A Combination Of Antibiotics To Effectively Eradicate Pre Formed Biofilms In Vitro Book
Author : Cate Winstanley
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

INTRODUCTION: Over 65% of bacterial infections treated clinically in the developed world are now known to be caused by organisms growing in biofilms. Biofilms are matrix-enclosed communities of bacteria which are significantly more resistant to host defences and to conventional therapies compared to their planktonic counterparts. Device-related infections (such as periprosthetic infections) can be unresponsive to orally administered antibiotics that have virtually eliminated acute infections caused by planktonic bacteria. In addition, bioufb01lm-related periprosthetic infections lack a deufb01nitive diagnosis because matrix-enclosed sessile bacteria are less immunogenic and elicit a reduced inflammatory response compared to planktonic cells. Implantable devices are highly susceptible to infection and biofilm formation. Once a biofilm has been established in a periprosthetic joint it is difficult to diagnose and eradicate. Successful treatment of periprosthetic joint infection requires the optimal surgical procedure combined with long-term antimicrobial therapy directed against surface-adhering microorganisms. Given the limited efficacy of traditional antibiotics in implant-associated infections, novel strategies such as releasing antibiotics directly to the site of infection are a promising future option for biofilm prevention and eradication. The objective of the study was to assess the ability of Stimulanu00ae beads containing a mixture of Vancomycin and Gentamicin or Vancomycin and Tobramycin to release a combination of antibiotics and effectively eradicate pre-formed biofilms in vitro. METHODS: Single species Pseudomonas aeruginosa and Staphylococcus aureus biofilms were established on polycarbonate coupons within a CDC biofilm reactor (Figure 1). Biofilms were established in a batch model for 72 hours prior to processing. Following incubation, established biofilms were removed from the reactor and rinsed in phosphate buffered saline to remove planktonic organisms. Washed biofilms were exposed to a challenge plate containing suspended Stimulanu00ae beads containing a mixture of Vancomycin and Gentamicin or Vancomycin and Tobramycin. Positive and negative controls were tested concurrently. All testing was performed in triplicate. The challenge plate was incubated for 24 hours at 37u00b0C u00b1 2u00b0C. Following exposure, remaining attached organisms were recovered by sonication. Serial dilutions and plate counts were performed on the resultant suspensions. Log reductions compared to the negative control were reported. Students T-Tests were performed on the raw data to determine the significant effect of the test items. RESULTS SECTION: An average of 6.78 u00b1 0.23 Log10CFUmL-1 were recovered from triplicate negative control seventy-two-hour Pseudomonas aeruginosa biofilms. An average of 6.60 u00b1 0.23 Log10CFUmL-1 were recovered from negative control seventy-two-hour Staphylococcus aureus biofilms. No viable organisms were recovered from biofilms exposed to the positive control. No viable P. aeruginosa and S. aureus were recovered from biofilms exposed to Stimulanu00ae beads containing a mixture of Vancomycin and Gentamicin or Vancomycin and Tobramycin within detection limits (Figure 2). This equated to an average log reduction in P. aeruginosa of >5.78 Log10CFUmL-1 and an average log reduction in S. aureus of >5.60 Log10CFUmL-1 (p

Handbook of Pediatric Infection Prevention and Control

Handbook of Pediatric Infection Prevention and Control Book
Author : Kristina A. Bryant,Judith A. Guzman-Cottrill
Publisher : Oxford University Press
Release : 2019-03-14
ISBN : 0190697180
Language : En, Es, Fr & De

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Book Description :

AN INNOVATIVE AND ESSENTIAL NEW TOOL IN FIGHTING HEALTHCARE-ASSOCIATED INFECTIONS The Handbook of Pediatric Infection Prevention and Control is the most comprehensive, practical resource available on infection prevention across the spectrum of pediatric healthcare settings, including acute care hospitals, ambulatory practices, and long-term care facilities. It addresses the nuances and challenges specific to pediatric infection prevention, providing expert guidance on topics where evidence-based guidelines don't currently exist. Expertly written and exceptionally practical, this handbook is an essential resource for infection preventionists, healthcare epidemiologists, infectious disease fellows, and anyone who provides support for infection-prevention programs in pediatric facilities. *** The Handbook of Pediatric Infection Prevention and Control is a publication of the Pediatric Infectious Diseases Society, the world's largest organization dedicated to the treatment, control, and eradication of infectious diseases that affect children.

Infection Prevention

Infection Prevention Book
Author : Gonzalo Bearman,Silvia Munoz-Price,Daniel J. Morgan,Rekha K. Murthy
Publisher : Springer
Release : 2017-09-07
ISBN : 3319609807
Language : En, Es, Fr & De

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Book Description :

This book reviews evolving areas in infection prevention on topics including contact precautions, technology implementation, specific infections, and care in various settings. The book summarizes the current data oninfection prevention, presents controversies on the various topics, and includes recommendations for patient safety. Addressing hot topics such as MRSA, C. difficile vaccination, mandatory flu vaccines, and CLABSI, this is the only text to include prevention and control overviews across a range of infection issues. Written by experts in thefield, this book contains 32 chapters that educates and presents the most cutting-edge models of care on emerging and evolving topics in infectious diseases. Infection Prevention: New Perspectives and Controversies is a valuable resource for infection prevention professionals, healthcare quality and safety professionals, caring for patients in in- and outpatient settings.