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Bioconjugate Techniques

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Bioconjugate Techniques

Bioconjugate Techniques Book
Author : Greg T. Hermanson
Publisher : Academic Press
Release : 2013-07-25
ISBN : 0123822408
Language : En, Es, Fr & De

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Book Description :

Bioconjugate Techniques, 3rd Edition, is the essential guide to the modification and cross linking of biomolecules for use in research, diagnostics, and therapeutics. It provides highly detailed information on the chemistry, reagent systems, and practical applications for creating labeled or conjugate molecules. It also describes dozens of reactions, with details on hundreds of commercially available reagents and the use of these reagents for modifying or crosslinking peptides and proteins, sugars and polysaccharides, nucleic acids and oligonucleotides, lipids, and synthetic polymers. Offers a one-stop source for proven methods and protocols for synthesizing bioconjugates in the lab Provides step-by-step presentation makes the book an ideal source for researchers who are less familiar with the synthesis of bioconjugates Features full color illustrations Includes a more extensive introduction into the vast field of bioconjugation and one of the most thorough overviews of immobilization chemistry ever presented

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging

The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging Book
Author : Andre S. Merbach,Lothar Helm,Éva Tóth
Publisher : John Wiley & Sons
Release : 2013-02-19
ISBN : 1118503678
Language : En, Es, Fr & De

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Book Description :

Magnetic Resonance Imaging (MRI) is one of the most important tools in clinical diagnostics and biomedical research. The number of MRI scanners operating around the world is estimated to be approximately 20,000, and the development of contrast agents, currently used in about a third of the 50 million clinical MRI examinations performed every year, has largely contributed to this significant achievement. This completely revised and extended second edition: Includes new chapters on targeted, responsive, PARACEST and nanoparticle MRI contrast agents. Covers the basic chemistries, MR physics and the most important techniques used by chemists in the characterization of MRI agents from every angle from synthesis to safety considerations. Is written for all of those involved in the development and application of contrast agents in MRI. Presented in colour, it provides readers with true representation and easy interpretation of the images. A word from the Authors: Twelve years after the first edition published, we are convinced that the chemistry of MRI agents has a bright future. By assembling all important information on the design principles and functioning of magnetic resonance imaging probes, this book intends to be a useful tool for both experts and newcomers in the field. We hope that it helps inspire further work in order to create more efficient and specific imaging probes that will allow materializing the dream of seeing even deeper and better inside the living organisms. Reviews of the First Edition: "...attempts, for the first time, to review the whole spectrum of involved chemical disciplines in this technique..."—Journal of the American Chemical Society "...well balanced in its scope and attention to detail...a valuable addition to the library of MR scientists..."—NMR in Biomedicine

Biological Chemistry of Arsenic Antimony and Bismuth

Biological Chemistry of Arsenic  Antimony and Bismuth Book
Author : Hongzhe Sun
Publisher : John Wiley & Sons
Release : 2010-12-10
ISBN : 0470976225
Language : En, Es, Fr & De

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Book Description :

Arsenic, antimony and bismuth, three related elements of group 15, are all found in trace quantities in nature and have interesting biological properties and uses. While arsenic is most well known as a poison - and indeed the contamination of groundwater by arsenic is becoming a major health problem in Asia - it also has uses for the treatment of blood cancer and has long been used in traditional chinese medicine. Antimony and bismuth compounds are used in the clinic for the treatment of parasitic and bacterial infections. Biological Chemistry of Arsenic, Antimony and Bismuth is an essential overview of the biological chemistry of these three elements, with contributions from an international panel of experts. Topics covered include: chemistry of As, Sb and Bi biological chemistry of arsenic biological chemistry of Sb and Bi arsenic and antimony speciation in environmental and biological samples arsenic in traditional chinese medicine arsenic in aquifers biomethylation of As, Sb and Bi uptake of metalloids by cells bismuth complexes of porphyrins and their potential in medical applications Helicobacter pylori and bismuth metabolism of arsenic trioxide in blood of the acute promyelocytic leukemia patients anticancer properties of As, Sb and Bi radio-Bi in cancer therapy genotoxicity of As, Sb and Bi metallomics as a new technique for As, Sb and Bi metalloproteomics for As, Sb and Bi Biological Chemistry of Arsenic, Antimony and Bismuth conveys the essential aspects of the bioinorganic chemistry of these three elements, making this book a valuable complement to more general bioinorganic chemistry texts and more specialized topical reviews. It will find a place on the bookshelves of practitioners, researchers and students working in bioinorganic chemistry and medicinal chemistry.

The Chemistry of Molecular Imaging

The Chemistry of Molecular Imaging Book
Author : Nicholas Long,Wing-Tak Wong
Publisher : John Wiley & Sons
Release : 2014-11-24
ISBN : 1118854810
Language : En, Es, Fr & De

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Book Description :

Molecular imaging is primarily about the chemistry of novelbiological probes, yet the vast majority of practitioners are notchemists or biochemists. This is the first book, written from achemist's point of view, to address the nature of the chemicalinteraction between probe and environment to help elucidatebiochemical detail instead of bulk anatomy. Covers all of the fundamentals of modern imaging methodologies,including their techniques and application within medicine andindustry Focuses primarily on the chemistry of probes and imagingagents, and chemical methodology for labelling andbioconjugation First book to investigate the chemistry of molecularimaging Aimed at students as well as researchers involved in the areaof molecular imaging

Gel Electrophoresis of Proteins

Gel Electrophoresis of Proteins Book
Author : B. D. Hames
Publisher : OUP Oxford
Release : 1998-10-01
ISBN : 0191565636
Language : En, Es, Fr & De

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Book Description :

This new edition of Gel Electrophoresis of Proteins is a completely new text, with eight of the ten chapters written by new authors. It presents the best methods, hints and tips for core procedures such as one- dimensional polyacrylamide gel electrophoresis, isoelectric focusing, two-dimensional gel electrophoresis, preparative gel electrophoresis, and peptide mapping, complete with the latest refinements and updates of the procedures. In addition, it describes major new techniques which have come to the fore since the previous edition. Thus there are chapters on capillary gel electrophoresis, sequence analysis of gel-resolved proteins, fluorophore-labelled saccharide electrophoresis, and analysis of protein:protein interactions by gel electrophoresis. One thing has not changed. The emphasis is still on describing the best methods, in step-by-step detail, with copious advice to ensure that each method works first time in the reader's hands. The first two editions of Gel Electrophoresis of Proteins: A Practical Approach each gained a strong reputation as easy-to-follow laboratory manuals written by experienced researchers for researchers. The methods were presented in a clear accessible format and had been fully tested to ensure success in the lab. This new edition will strengthen the reputation of the book still further. It is a 'must have' for all those who currently use gel electrophoresis or who plan to do so.

Immunoassays in Agricultural Biotechnology

Immunoassays in Agricultural Biotechnology Book
Author : Guomin Shan
Publisher : John Wiley & Sons
Release : 2011-04-27
ISBN : 9780470922682
Language : En, Es, Fr & De

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Book Description :

A very broad range of professionals are using immunoassay technology daily to analyze genetically engineered (GE) crops and related areas, and many of these professionals are completely new to this technology. There is a great need for users to have a book containing technical and practical guidance, and describing limitations and pitfalls of applying immunoassay in agricultural biotechnology. This book focuses on the application of immunoassays to GE plants and related areas. A group of international experts from government agencies, academics and industries, who have many years of related experience, contribute high quality chapters in their areas of expertise. This book covers topics including principles of immunoassay, antibody engineering in AgBiotech, current technologies (formats, kit development, manufacturing and quality control), method validation, applications in trait discovery and product development, applications in grain products and food processing, applications in environmental monitoring, automation and high throughput, reference materials, data interpretation and source of error, and future perspectives and challenges. In addition, to meet the practical needs for a variety of readers from different backgrounds, methods and protocols are included as well.

Molecular Solar Fuels

Molecular Solar Fuels Book
Author : Thomas John Wydrzynski,Warwick Hillier
Publisher : Royal Society of Chemistry
Release : 2011
ISBN : 1849730342
Language : En, Es, Fr & De

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Book Description :

Written by experts, this book presents the latest knowledge and chemical prospects in developing hydrogen as a solar fuel.

Hodgkin s Lymphoma An Issue of Hematology Oncology

Hodgkin s Lymphoma  An Issue of Hematology Oncology  Book
Author : Volker Diehl
Publisher : Elsevier Health Sciences
Release : 2014-02-09
ISBN : 0323266614
Language : En, Es, Fr & De

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Book Description :

This issue of Hematology/Oncology Clinics is focused on Hodgkin's Lymphoma and covers such topics as First HRS-cell line L428 and the detection of the CD-30 Antigen , “Normal“ CD30-B-lymphocytes, CD-30-Antigen, Combination-Chemo-Radiotherapy, Early intensification (escBEACOPP), Customized/Targeted Therapy, and more.

Comprehensive Biomaterials

Comprehensive Biomaterials Book
Author : Paul Ducheyne,Kevin Healy,Dietmar W. Hutmacher,David W. Grainger,C. James Kirkpatrick
Publisher : Elsevier
Release : 2015-08-28
ISBN : 0080552943
Language : En, Es, Fr & De

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Book Description :

Comprehensive Biomaterials brings together the myriad facets of biomaterials into one, major series of six edited volumes that would cover the field of biomaterials in a major, extensive fashion: Volume 1: Metallic, Ceramic and Polymeric Biomaterials Volume 2: Biologically Inspired and Biomolecular Materials Volume 3: Methods of Analysis Volume 4: Biocompatibility, Surface Engineering, and Delivery Of Drugs, Genes and Other Molecules Volume 5: Tissue and Organ Engineering Volume 6: Biomaterials and Clinical Use Experts from around the world in hundreds of related biomaterials areas have contributed to this publication, resulting in a continuum of rich information appropriate for many audiences. The work addresses the current status of nearly all biomaterials in the field, their strengths and weaknesses, their future prospects, appropriate analytical methods and testing, device applications and performance, emerging candidate materials as competitors and disruptive technologies, and strategic insights for those entering and operational in diverse biomaterials applications, research and development, regulatory management, and commercial aspects. From the outset, the goal was to review materials in the context of medical devices and tissue properties, biocompatibility and surface analysis, tissue engineering and controlled release. It was also the intent both, to focus on material properties from the perspectives of therapeutic and diagnostic use, and to address questions relevant to state-of-the-art research endeavors. Reviews the current status of nearly all biomaterials in the field by analyzing their strengths and weaknesses, performance as well as future prospects Presents appropriate analytical methods and testing procedures in addition to potential device applications Provides strategic insights for those working on diverse application areas such as R&D, regulatory management, and commercial development

Nanoscale Sensors

Nanoscale Sensors Book
Author : Shibin Li,Jiang Wu,Zhiming M. Wang,Yadong Jiang
Publisher : Springer Science & Business Media
Release : 2014-01-07
ISBN : 3319027727
Language : En, Es, Fr & De

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Book Description :

This book is a comprehensive introduction to nanoscale materials for sensor applications, with a focus on connecting the fundamental laws of physics and the chemistry of materials with device design. Nanoscale sensors can be used for a wide variety of applications, including the detection of gases, optical signals, and mechanical strain, and can meet the need to detect and quantify the presence of gaseous pollutants or other dangerous substances in the environment. Gas sensors have found various applications in our daily lives and in industry. Semiconductive oxides, including SnO2, ZnO, Fe2O3, and In2O3, are promising candidates for gas sensor applications. Carbon nanomaterials are becoming increasingly available as “off-the-shelf” components, and this makes nanotechnology more exciting and approachable than ever before. Nano-wire based field- effect transistor biosensors have also received much attention in recent years as a way to achieve ultra-sensitive and label-free sensing of molecules of biological interest. A diverse array of semiconductor-based nanostructures has been synthesized for use as a photoelectrochemical sensor or biosensor in the detection of low concentrations of analytes. A novel acoustic sensor for structural health monitoring (SHM) that utilizes lead zirconate titanate (PZT) nano- active fiber composites (NAFCs) is described as well.

Methods in Bioengineering

Methods in Bioengineering Book
Author : Kaushal Rege,Igor L. Medintz
Publisher : Artech House
Release : 2009
ISBN : 1596934115
Language : En, Es, Fr & De

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Book Description :

Filling a critical gap in the current literature, this new resource presents practical, step-by-step methods to help you synthesize, characterize, biofunctionalize and apply the nanomaterial that is most suitable for handling a given nanoscale bioengineering problem. Written and presented by leading scientists and engineers in their respective fields, the authors offer a clear and detailed understanding of how to carry out nanoparticle functionalization with biomolecules (including enzymes), nanoparticle analysis and characterization, in vitro evaluation of nanoparticles using different cell lines and in vitro evaluation of nanoparticles as therapeutics and imaging agents.

Bioconjugation

Bioconjugation Book
Author : Mohammed Aslam,Alastair Dent
Publisher :
Release : 1998
ISBN :
Language : En, Es, Fr & De

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Book Description :

Recent years have seen an enormous increase in the use of protein reagents in the biological and medical sciences. Enzyme conjugates and immobilised proteins are fundamental to many diagnostic applications, and existing therapeutic advances are being made using a range of approaches based on antibody conjugates. Protein conjugation techniques are central to the development of these reagents.

Mechanical and Electrical Technology IV

Mechanical and Electrical Technology IV Book
Author : Mohamed Othman
Publisher : Trans Tech Publications Ltd
Release : 2012-11-29
ISBN : 3038133159
Language : En, Es, Fr & De

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Book Description :

These proceedings of the 4th International Conference on Mechanical and Electrical Technology (ICMET 2012), held during the 24 to 26th July 2012 in Kuala Lumpur, Malaysia, take the form of 614 peer-reviewed papers grouped as follows: Materials Engineering; Applied Mechanics and Mechanical Engineering; Electrotechnics and Electrical Machines; Energy and Power Engineering; Measurements, Monitoring and Sensors; Electronic and Radio Engineering; Computer-Aided Design and Technology; Control and Automation; Manufacturing Processes and Technology.

Encyclopedia of Molecular Biology Volume 2

Encyclopedia of Molecular Biology  Volume 2 Book
Author : Thomas E. Creighton
Publisher : Wiley-Interscience
Release : 1999
ISBN :
Language : En, Es, Fr & De

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Book Description :

Annotation The field of molecular biology has revolutionized the study of biology. The applications to medicine are enormous, ranging from diagnostic techniques for disease and genetic disorders, to drugs, to gene therapy. Focusing on the fundamentals of molecular biology and encompassing all aspects of the expression of genetic information, the Encyclopedia of Molecular Biology will become the first point of reference for both newcomers and established professionals in molecular biology needing to learn about any particular aspect of the field.

Encyclopedia of Physical Science and Technology

Encyclopedia of Physical Science and Technology Book
Author : Robert Allen Meyers
Publisher :
Release : 2002
ISBN : 9780122274121
Language : En, Es, Fr & De

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Book Description :

Following in the footsteps of the earlier editions, hundreds of the most respected scientists and engineers participated in the creation of this new edition, including many Nobel Laureates. The articles are in-depth, yet accessible, and address all of the key areas of physical science--including aeronautics, astronomy, chemistry, communications, computers, earth sciences, electronics, engineering, materials science, mathematics, nuclear technology, physics, power systems, propulsion, and space technology. (Midwest).