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Bioactive Natural Products Part B

Bioactive Natural Products  Part B  Book
Author : Atta-ur-Rahman
Publisher : Elsevier
Release : 2000-03-09
ISBN : 9780080542010
Language : En, Es, Fr & De

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Book Description :

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

Pharmaceutical and Bioactive Natural Products

Pharmaceutical and Bioactive Natural Products Book
Author : David H. Attaway,Oskar R. Zaborsky
Publisher : Springer
Release : 2013-05-30
ISBN : 9781489923936
Language : En, Es, Fr & De

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Book Description :

Biotechnology may be defined as the application of scientific and engineering principles to the processing of materials by biological agents to provide goods and services (Bullet al. , 1982, p. 21) or as any technique that uses living organisms (or parts of organisms) to make or modify products, to improve plants or animals, or to develop microorganisms for specific use (OTC, 1988). In line with these broad definitions we can consider marine biotechnology as the use of marine organisms or their constituents for useful purposes in a controlled fashion. This series will explore a range of scientific advances in support of marine biotechnology. It will provide information on advances in three categories: (1) basic knowledge, (2) ap plied research and development, and (3) commercial and institutional issues. We hope the presentation of the topics will generate interest and interaction among readers in the academic world, government, and industry. This first volume examines chemical and biological properties of some natural products that are useful or potentially useful in research and in the chemical and pharmaceutical industries. One chapter describes a system for producing such substances on a large scale. Biotechnology incorporates molecular biology in order to go beyond tradi tional biochemical technology such as the production of antibiotic drugs from bacterial cultures in bioreactors. Development of the technology for production of antibiotics in this way resulted from fundamental advances in chemistry, phar macology, microbiology, and biochemical engineering.

Bioactive Natural Products Detection Isolation and Structural Determination

Bioactive Natural Products Detection  Isolation  and Structural Determination Book
Author : Steven M. Colegate,Russell J. Molyneux
Publisher : CRC Press
Release : 1993-09-29
ISBN : 9780849343728
Language : En, Es, Fr & De

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Book Description :

Bioactive Natural Products covers all the aspects of bioactive natural product research from ethnobotanical investigations to modern, technologically assisted isolation and structural determination of active compounds. An internationally selected group of experts share their knowledge of a wide range of bioactivities and chemical compound classes. Topics in the chapters describing the modern application of detection, isolation, and structural determination techniques are strongly supported by chapters detailing and reviewing research involving various classes of bioactivity. Research areas include the immunomodulatory, antiviral, cytotoxic, anti-inflammatory, and insect behavior classes of bioactivity. Extensive referencing throughout the text is helpful to those readers not familiar with this subject and serves as a critical review for more experienced researchers. The book is also excellent for upper division or post-graduate courses.

Bioactive Natural Products

Bioactive Natural Products Book
Author : Steven M. Colegate,Russell J. Molyneux
Publisher : CRC Press
Release : 2007-12-14
ISBN : 1420006886
Language : En, Es, Fr & De

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Book Description :

Bioactive natural products are proving to be a rich source of novel therapeutics to both protect against and combat diseases, as well as serve as lead compounds in crop protection. Following the successful format of the first edition, this volume brings together collective research from many new contributors and emphasizes the rationale behind the

Bioactive Compounds from Natural Sources Second Edition

Bioactive Compounds from Natural Sources  Second Edition Book
Author : Corrado Tringali
Publisher : CRC Press
Release : 2011-09-27
ISBN : 1439822298
Language : En, Es, Fr & De

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Book Description :

The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified—natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics. Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, The tremendous potentiality of metabolic engineering of natural products biosynthesis The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Atta-ur- Rahman
Publisher : Elsevier
Release : 2012
ISBN : 0444538364
Language : En, Es, Fr & De

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Book Description :

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. "There is a good mix of chemistry, structure elucidation, synthesis, and biology in the various chapters, thereby appealing to a diverse readership. The diagrams are clear and the writing excellent. In summary, this is another excellent volume in a very valuable series on natural products for which Professor Atta-ur-Rahman is to be congratulated...... an important and essential asset for those libraries supporting the efforts of natural product research groups." Geoffrey A. Cordell, University of Illinois, Chicago, USA, PHYTOCHEMISTRY, Vol.65, 2004 Describes the chemistry of bioactive natural products Contains contributions by leading authorities in the field A valuable source for researchers and engineers working in natural product and medicinal chemistry

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Atta-ur-Rahman
Publisher : Elsevier
Release : 2020-03-04
ISBN : 0128179031
Language : En, Es, Fr & De

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Book Description :

Studies in Natural Products Chemistry, Volume 64, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Marine Microbial Diversity as a Source of Bioactive Natural Products

Marine Microbial Diversity as a Source of Bioactive Natural Products Book
Author : Didier Stien
Publisher : MDPI
Release : 2020-06-17
ISBN : 3039361821
Language : En, Es, Fr & De

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Book Description :

A trillion different microbial species have been evolving for some 3.5 billion years, producing ever more complex active secondary metabolites. The sea is a cauldron of a great diversity of useful and valuable compounds. This Special Issue focused on studies of marine microbe natural products for discovering compounds useful to humankind. Papers were collected that provide up-to-date information regarding the characterization of marine microbes’ metabolic diversity and the evaluation of the therapeutic potential of marine microbes’ metabolites. Most of the articles in this book deal with marine fungi, biological and chemical diversity, and their active metabolites. This may be a sign that marine fungi have been under studied to date and are perceived by many researchers as an important source of discovery in this field. A best practices guide for the isolation of marine fungi from different matrixes and their conservation is also presented. The comparison of the phylogenetic and metabolomic profiles of microalgae from different lineages provides novel insights into the potential of chemotaxonomy in marine phytoplankton, showing a good overlap of phylogenetic and chemotaxonomic signals.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Anonim
Publisher : Elsevier
Release : 2016-06-20
ISBN : 0444636102
Language : En, Es, Fr & De

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Book Description :

Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development. The series covers all aspects of the science, along with the synthesis, testing, and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, the book presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry. Provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures Focuses on the chemistry of bioactive natural products and their exciting new applications in the pharmaceutical industry Presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products Contains contributions by leading authorities in the field

Medicinal Chemistry of Bioactive Natural Products

Medicinal Chemistry of Bioactive Natural Products Book
Author : Xiao-Tian Liang,Wei-Shuo Fang
Publisher : John Wiley & Sons
Release : 2006-03-17
ISBN : 0471739332
Language : En, Es, Fr & De

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Book Description :

Current discoveries and research into bioactive naturalproducts Medicinal Chemistry of Bioactive Natural Products provides amuch-needed survey of bioactive natural products and theirapplications in medicinal chemistry. This comprehensive referencefeatures articles by some of the world's leading scientists in thefield on discovery, structure elucidation, and elegant syntheticstrategies--developed for natural products--with an emphasis on thestructure activity relationship of bioactive natural products. Thetopics have been carefully chosen on the basis of relevance tocurrent research and to importance as clinicially usefulagents. Rather than attempting to be a comprehensive encyclopedia ofbioactive natural products, Medicinal Chemistry of BioactiveNatural Products guides the reader to the key developments in thefield. By providing not only practical detail but a historicalperspective on the chemistry and biology of the compounds underconsideration, the book serves as a handy resource for researchersin their own work developing pharmaceuticals, and as an inspiringintroduction for young scientists to the dynamic field of bioactivenatural products research. Enhanced by examples with updated research results, the discussioncovers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and itsanalogs * The antimalarial properties of the traditional Chinese medicine,Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer'sdisease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIVagents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and theirstructurally modified mimics

Total Synthesis of Bioactive Natural Products by Palladium Catalyzed Domino Cyclization of Allenes and Related Compounds

Total Synthesis of Bioactive Natural Products by Palladium Catalyzed Domino Cyclization of Allenes and Related Compounds Book
Author : Shinsuke Inuki
Publisher : Springer Science & Business Media
Release : 2011-11-23
ISBN : 9784431540434
Language : En, Es, Fr & De

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Book Description :

The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Atta-ur-Rahman
Publisher : Elsevier
Release : 2003-07-08
ISBN : 9780080542058
Language : En, Es, Fr & De

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Book Description :

Studies in Natural Products Chemistry: Bioactive Natural Products (Part I) contains articles written by leading authorities in their respective fields of research. It presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. Volume 28 is part of a great family of useful reference books Illustrates the types of critical discoveries that emerge from the interface of chemistry and biology Contributions are from well-respected authors

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Atta-ur- Rahman
Publisher : Elsevier
Release : 2011-08-30
ISBN : 9780080458472
Language : En, Es, Fr & De

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Book Description :

Natural Product Chemistry continues to expand to exciting new frontiers of great importance in medicine. Written by international authorities in various fields of natural product chemistry, this latest volume in the well-established series Studies in Natural Products Chemistry contains 23 chapters, covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases. This present volume, will again be of great interest to research scientists and scholars working in the exciting field of new drug discovery. * Written by international authorities in the various fields of natural product chemistry * Contains 23 comprehensive articles covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases * Valuable source of information for research scientists and scholars in the field of new drug discovery

Structure and Synthesis of Bioactive Natural Products

Structure and Synthesis of Bioactive Natural Products Book
Author : Zimbili Mkhize
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Structure and Synthesis of Bioactive Natural Products book written by Zimbili Mkhize, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Anonim
Publisher : Elsevier
Release : 2018-11-29
ISBN : 0444641823
Language : En, Es, Fr & De

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Book Description :

Studies in Natural Products Chemistry, Volume 60 covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Bioactive Natural Products

Bioactive Natural Products Book
Author : Atta-ur- Rahman
Publisher : Elsevier Science Limited
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the 28th volume in the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance. The first paper presents over 100 compounds obtained from Broussonetia spp., and discusses biological activities. This is followed by similar contributions dealing with the genus Licania and Ginkgo biloba. Additional papers describe in detail a number of interesting and important natural compounds or structural classes: retinoids, tetramic acid metabolites, isoprenylated flavonoids, plant polyphenols, crocin, marcfortine and paraherquamide, acaricides, podolactones, triterpene glycosides and sulfur-containing marine compounds. An additional paper focuses on the antitumor activities of lipids, and a final contribution deals with natural product amelioration of cancer chemotherapy-induced adverse reactions.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Atta-Ur Rahman
Publisher : Elsevier Science Limited
Release : 2005
ISBN : 9780444518545
Language : En, Es, Fr & De

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Book Description :

Many aspects of basic research programmes are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 30 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural product, and medicinal chemistry. * Describes the chemistry of bioactive natural products * Contains contributions by leading authorities in the field * A valuable source for researchers and engineers working in natural product, and medicinal chemistry

Bioactive Natural products in Drug Discovery

Bioactive Natural products in Drug Discovery Book
Author : Joginder Singh,Vineet Meshram,Mahiti Gupta
Publisher : Springer Nature
Release : 2020-04-30
ISBN : 9811513945
Language : En, Es, Fr & De

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Book Description :

This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Anonim
Publisher : Elsevier
Release : 2016-09-06
ISBN : 0444636099
Language : En, Es, Fr & De

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Book Description :

Studies in Natural Products Chemistry: Bioactive Natural Products (Part XII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry Book
Author : Atta-ur-Rahman
Publisher : Elsevier Science
Release : 2006
ISBN : 9780444527172
Language : En, Es, Fr & De

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Book Description :

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions. * Timely reviews written by international authorities in the field * Topics ranging from purely chemical to very biological * The 13th volume in the series to be devoted to bioactive natural products