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Biotechnological Production of Bioactive Compounds

Biotechnological Production of Bioactive Compounds Book
Author : Madan L. Verma,Anuj Chandel
Publisher : Elsevier
Release : 2019-07-20
ISBN : 0444643249
Language : En, Es, Fr & De

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Book Description :

Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits “bioactives’’ from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. Outlines technological advances in bioactives extraction Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules

Bioactive Compounds from Natural Sources Second Edition

Bioactive Compounds from Natural Sources  Second Edition Book
Author : Corrado Tringali
Publisher : CRC Press
Release : 2011-09-27
ISBN : 1439822298
Language : En, Es, Fr & De

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Book Description :

The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified—natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products as lead compounds in drug discovery, Bioactive Compounds from Natural Sources, Second Edition: Natural Products as Lead Compounds in Drug Discovery is actually a completely new volume containing surveys of selected recent advances in an interdisciplinary area covering chemistry of natural products, medicinal chemistry, biochemistry, and other related topics. Written by some of the most reputed scientists in the field, this second edition includes new chapters from authors who contributed to the first edition as well as many chapters compiled by new authors. Introducing the reader to strategies and methods in the search for bioactive natural products, this book covers topics including: Natural sources of bioactive compounds such as aquatic cyanobacteria, filamentous fungi, and tropical plants, The tremendous potentiality of metabolic engineering of natural products biosynthesis The contribution of emerging or developing technologies to the study of bioactive natural compounds, namely computational methods and circular dichroism The potential of natural or natural-derived compounds for specific therapeutic applications: treatment of viral diseases, regulation of hypoxia-inducible factor, antimalarials, modulation of angiogenesis, and antitumor and wound-healing activity Selected examples of natural product families and related synthetic analogues, namely polyphenols and campthotecins Compiled for researchers and Ph.D. students working in interdisciplinary fields, this book will also be appreciated by readers without a background in chemistry interested in bioactive natural products, their biological and pharmacological properties, and their possible use as chemopreventive or chemotherapeutic agents. Conversely, the biological and pharmacological data and methods are accessible by chemists.

Marine Bioactive Compounds

Marine Bioactive Compounds Book
Author : Maria Hayes
Publisher : Springer Science & Business Media
Release : 2011-11-19
ISBN : 9781461412472
Language : En, Es, Fr & De

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Book Description :

The aim and scope of this book is to highlight the sources, isolation, characterization and applications of bioactive compounds from the marine environment and to discuss how marine bioactive compounds represent a major market application in food and other industries. It discusses sustainable marine resources of macroalgal origin and gives examples of bioactive compounds isolated from these and other resources, including marine by-product and fisheries waste streams. In addition, it looks at the importance of correct taxonomic characterization.

Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds

Supercritical Fluid Extraction of Nutraceuticals and Bioactive Compounds Book
Author : Jose L. Martinez
Publisher : CRC Press
Release : 2007-11-28
ISBN : 1420006517
Language : En, Es, Fr & De

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Book Description :

Enhanced concern for the quality and safety of food products, increased preference for natural products, and stricter regulations on the residual level of solvents, all contribute to the growing use of supercritical fluid technology as a primary alternative for the extraction, fractionation, and isolation of active ingredients. As a solvent-free p

Water Extraction of Bioactive Compounds

Water Extraction of Bioactive Compounds Book
Author : Herminia Dominguez,Maria Jesus Gonzalez Munoz
Publisher : Elsevier
Release : 2017-09-20
ISBN : 0128096152
Language : En, Es, Fr & De

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Book Description :

Water Extraction of Bioactive Compounds: From Plants to Drug Development draws together the expert knowledge of researchers from around the world to outline the essential knowledge and techniques required to successfully extract bioactive compounds for further study. The book is a practical tool for medicinal chemists, biochemists, pharmaceutical scientists and academics working in the discovery and development of drugs from natural sources. The discovery and extraction of bioactive plant compounds from natural sources is of growing interest to drug developers, adding greater fuel to a simultaneous search for efficient, green technologies to support this. Particularly promising are aqueous based methods, as water is a cheap, safe and abundant solvent. The book is a detailed guide to the fundamental concepts and necessary equipment needed to successfully undertake such processes, supported by application examples and highlighting the most influential variables. Part 1 begins with a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals, the need for standardization and a move toward more rational and greener techniques in the field, the development of plant-based extraction processes and pretreatments for the efficient extraction. Part 2 then reviews a broad range of available techniques, including sections on conventional hot water extraction and pressurized hot water extraction in a range of settings. Intensified processes are then discussed in detail, including sections on microwave-assisted processes, ultrasound-assisted processes and enzyme assisted extraction. Covers the theoretical background and range of techniques available to researchers, helping them to select the most appropriate extraction method for their needs Presents up-to-date and cutting edge applications by international experts Highlights current use and future potential for industrial scale applications Offers a thorough introduction to plants as sources of drugs, highlighting strategies for the discovery of novel bioactive constituents of botanicals

Naturally Occurring Bioactive Compounds

Naturally Occurring Bioactive Compounds Book
Author : Anonim
Publisher : Elsevier
Release : 2006-09-25
ISBN : 9780080464923
Language : En, Es, Fr & De

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Book Description :

This timely book provides an overview of natural products/botanicals used for the management of insect-pest and diseases. It will help readers to update and widen their knowledge about natural products and their bio-activities against plant pathogens. The volume explores activity, chemistry, toxicity and geographic distribution of plants. Discussions concerning the methodology used for the detection of active principles, their mode of action and commercial prospects are of utmost importance and worthy of note. Focuses on recent achievements in natural bio-actives Global coverage of natural products / plants Targets the most important issues of natural botanicals/ biocides Includes innovative ideas with lucid explanations Contains specialized chapters, such as, natural control of multi-drug resistant organisms, anti-salmonella agents, natural house-dust-mite control agents, and naturally occurring anti-insect proteins, etc. Covers research on bioactives: From Lab to Field and Field to Market Includes eco-friendly and economically viable herbal technology

Human Health Benefits of Plant Bioactive Compounds

Human Health Benefits of Plant Bioactive Compounds Book
Author : Megh R. Goyal,Hafiz Ansar Rasul Suleria
Publisher : CRC Press
Release : 2019-07-23
ISBN : 0429856164
Language : En, Es, Fr & De

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Book Description :

Focusing on the importance of functional foods and their secondary metabolites for human health, this volume presents new insights with scientific evidence on the use of functional foods in the treatment of certain diseases. The plants covered and their bioactive compounds are easily accessible and are believed to be effective with fewer side effects in comparison with modern drugs in the treatment of different diseases. The plants contain chemical compounds that can modify and modulate biological systems, eliciting therapeutic effects. Some plants and derived products mentioned include black carrot, olive oil, citrus peel, grapes, candy leaf, cereals and grains, and green and black tea. The volume is divided into four sections that cover these topics: Functional foods for human health: the available sources, biochemistry, structural composition, and different biological activities, especially antioxidant activity. Pharmacological aspects of fruits and vegetables: the extraction of bioactive molecules, phytochemistry, and biological activities of a selection of plants. Pharmacological aspects of natural products: bioactive compounds, structural attributes, bioactivity of anthocyanin, piceatannol, and a review of the ethnobotany and medicinal properties of green and black tea. Pharmacological aspects of cereals and grains: the health benefits of flaxseed, wheatgrass juice, and use and therapeutic potential as supplements for disease management.

Bioactive Compounds from Extremophiles

Bioactive Compounds from Extremophiles Book
Author : Lesley-Ann Giddings,David J. Newman
Publisher : Springer
Release : 2015-01-07
ISBN : 3319148362
Language : En, Es, Fr & De

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Book Description :

​This SpringerBrief sheds new light on bioactive materials from extremophiles with the focus on the biosynthesis processes and related genomics. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for human use.

Bioactive Compounds from Plant Origin

Bioactive Compounds from Plant Origin Book
Author : Hafiz Ansar Rasul Suleria,Colin Barrow
Publisher : Innovations in Plant Science for Better Health
Release : 2019-10-16
ISBN : 9781771887861
Language : En, Es, Fr & De

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Book Description :

This new volume explores the importance of phytochemicals from plants in therapeutics, focusing on the extraction of bioactive compounds and their applications in human health. Natural products and their bioactive compounds are increasingly utilized in preventive and therapeutic medication as well as for the production of pharmaceutical supplements and, more recently, as food additives to increase the functionality of foods. The first section of the volume describes recent advances in the extraction of bioactive compounds from various sources. It looks at advanced extraction techniques such as enzyme-assisted, microwave-assisted, ultrasound-assisted, pressurized liquid extraction, and supercritical extraction techniques. Part 2, on bioactive compounds and health claims, covers the roles of different bioactive compounds and their health-promoting potential for lifestyle diseases. This section explains the botany, physical characteristics, uniqueness, uses, distribution, importance, phytochemistry, bioactivities, and future trends of different functional foods.

Biotechnology of Bioactive Compounds

Biotechnology of Bioactive Compounds Book
Author : Vijai Kumar Gupta,Maria G. Tuohy,Anthonia O'Donovan,Mohtashim Lohani
Publisher : John Wiley & Sons
Release : 2015-04-20
ISBN : 1118733495
Language : En, Es, Fr & De

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Book Description :

Bioactive compounds play a central role in high-value product development in the chemical industry. Bioactive compounds have been identified from diverse sources and their therapeutic benefits, nutritional value and protective effects in human and animal healthcare have underpinned their application as pharmaceuticals and functional food ingredients. The orderly study of biologically active products and the exploration of potential biological activities of these secondary metabolites, including their clinical applications, standardization, quality control, mode of action and potential biomolecular interactions, has emerged as one of the most exciting developments in modern natural medicine. Biotechnology of Bioactive Compounds describes the current stage of knowledge on the production of bioactive compounds from microbial, algal and vegetable sources. In addition, the molecular approach for screening bioactive compounds is also discussed, as well as examples of applications of these compounds on human health. The first half of the book comprises information on diverse sources of bioactive compounds, ranging from microorganisms and algae to plants and dietary foods. The second half of the book reviews synthetic approaches, as well as selected bioactivities and biotechnological and biomedical potential. The bioactive compounds profiled include compounds such as C-phycocyanins, glycosides, phytosterols and natural steroids. An overview of the usage of bioactive compounds as antioxidants and anti-inflammatory agents, anti-allergic compounds and in stem cell research is also presented, along with an overview of the medicinal applications of plant-derived compounds. Biotechnology of Bioactive Compounds will be an informative text for undergraduate and graduate students of bio-medicinal chemistry who are keen to explore the potential of bioactive natural products. It also provides useful information for scientists working in various research fields where natural products have a primary role.

Bioactive Compounds from Marine Extremophiles

Bioactive Compounds from Marine Extremophiles Book
Author : Lesley-Ann Giddings,David J. Newman
Publisher : Springer
Release : 2015-01-06
ISBN : 3319143611
Language : En, Es, Fr & De

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Book Description :

​This SpringerBrief sheds new light on bioactive materials from marine extremophiles. It deals with all aspects of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or lead to novel drugs for human use.

Bioactive Compounds of Medicinal Plants

Bioactive Compounds of Medicinal Plants Book
Author : Megh R. Goyal,Ademola O. Ayeleso
Publisher : CRC Press
Release : 2018-07-04
ISBN : 1351376411
Language : En, Es, Fr & De

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Book Description :

This volume sheds new light on the immense potential of medicinal plants for human health from different technological aspects. It presents new research on bioactive compounds in medicinal plants that provide health benefits, including those that have proven especially effective in treating and managing diabetes mellitus and hypertension. It looks at the medicinal properties, antioxidant capacity, and antimicrobial activity of plants and provides scientific evidence on the use of medicinal plants in the treatment of certain diseases. Many of the plants described in the chapters are easily accessible and are believed to be effective with fewer side effects in comparison to modern drugs in the treatment of different diseases.

Innovative Processing Technologies for Foods with Bioactive Compounds

Innovative Processing Technologies for Foods with Bioactive Compounds Book
Author : Jorge J. Moreno
Publisher : CRC Press
Release : 2016-08-05
ISBN : 1315354098
Language : En, Es, Fr & De

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Book Description :

Natural foods, like fruits and vegetables, represent the simplest form of functional foods and provide excellent sources of functional compounds. Maximizing opportunities to make use of and incorporate these compounds requires special processing. Fortunately, technologies available to produce food with enhanced active compounds have advanced significantly over the last few years. This book covers the fundamentals as well as the innovations made during the last few years on the emerging technologies used in the development of food with bioactive compounds.

Bioactive Compounds in Foods

Bioactive Compounds in Foods Book
Author : John Gilbert,Hamide Şenyuva
Publisher : John Wiley & Sons
Release : 2009-01-21
ISBN : 1444302299
Language : En, Es, Fr & De

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Book Description :

Inherent toxicants and processing contaminants are bothnon-essential, bioactive substances whose levels in foods can bedifficult to control. This volume covers both types of compound forthe first time, examining their beneficial as well as theirundesirable effects in the human diet. Chapters have been writtenas individually comprehensive reviews, and topics have beenselected to illustrate recent scientific advances in understandingof the occurrence and mechanism of formation, exposure/riskassessment and developments in the underpinning analyticalmethodology. A wide range of contaminants are examined in detail,including pyrrolizidine alkaloids, glucosinolates, phycotoxins, andmycotoxins. Several process contaminants (eg acrylamide and furan),which are relatively new but which have a rapidly growingliterature, are also covered. The book provides a practical reference for a wide range ofexperts: specialist toxicologists (chemists and food chemists),hygienists, government officials and anyone who needs to be awareof the main issues concerning toxicants and process contaminants infood. It will also be a valuable introduction to the subject forpost-graduate students.

Metabolic Engineering for Bioactive Compounds

Metabolic Engineering for Bioactive Compounds Book
Author : Vipin Chandra Kalia,Adesh Kumar Saini
Publisher : Springer
Release : 2017-10-07
ISBN : 9811055114
Language : En, Es, Fr & De

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Book Description :

This book comprehensively discusses the latest research in the area of metabolic engineering. Metabolic engineering solutions for bioactive compounds are now being derived by means of heterologous gene expression, in a wide range of organisms. The book provides an overview of the model systems being employed for metabolic manipulation to yield bioactive molecules, such as single-cell proteins, antibody generation, metabolites, proteases, chaperones, therapeutic proteins, nanomaterials, polymeric conjugates, dendrimers and nanoassemblies, Escherichia coli, Agrobacterium, Saccharomyces cerevisiae and cell lines, etc. In addition, it shares insights into the scope of these methods in the areas of prevention, diagnosis and treatment of diseases, e.g. immunotherapy for curing various diseases like cancer, allergies, autoimmune diseases, etc.

Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters Part I

Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters Part I Book
Author : Luis Rodrigues da Silva , Branca Silva
Publisher : Bentham Science Publishers
Release : 2016-05-03
ISBN : 168108239X
Language : En, Es, Fr & De

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Book Description :

Plants have been widely used to treat diseases, owing to the presence of bioactive compounds (phytochemicals) which play important roles in health promotion and disease prevention. In recent years, advances in chemical extraction techniques, lifestyle and dietary choices for human health have increased the interest in the consumption and study of fruits, vegetables, and foods enriched with bioactive compounds and nutraceuticals. Thousands of dietary phytochemicals, such as flavonoids, phenolic acids, glucosinolates, terpenes and alkaloids, have been identified and categorized further according to a diverse array of biochemical properties. Many of these phytochemicals have been hypothesized to reduce the risk of several pathological conditions which include life threatening diseases such as heart disease and cancer, to name a few. Natural Bioactive Compounds from Fruits and Vegetables as Health Promoters is a 2 book set which presents a summary of different classes of phytochemicals commonly found in common edible food sources. Each chapter details the general chemical structures of compounds, naturally present in specific fruits, vegetables and grains, their biological importance and mechanisms of action. The book set is an essential handbook for anyone interested in the natural product chemistry of these common crops. Part 1 of this set covers details about different fruits (banana, citrus fruits, pears, etc.). Part 2 covers legumes, nuts, seeds and cereals.

Natural Sources Physicochemical Characterization and Applications

Natural Sources  Physicochemical Characterization and Applications Book
Author : Constantin Apetrei
Publisher : Bentham Science Publishers
Release : 2016-11-30
ISBN : 1681083418
Language : En, Es, Fr & De

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Book Description :

This volume presents different aspects related to bioactive compounds, starting with their natural state in raw sources, physicochemical characterization and employment in pharmacy and medicine. The volume is divided into three parts. The first part describes the chemicals structure of bioactive compounds from different natural sources such as olive oils, wines, and medicinal plants. Special attention has been given to identifying the bioactive composition within variations of these natural sources (for example, extra virgin, ordinary or lampante olive oils). The second part of the volume presents the principal methods used for detecting, identifying and quantifying bioactive compounds. Emphasis is given to the use of different types of sensors or biosensors, and multisensor systems in combination with analytical techniques. The final part explains the principal methods for protection of bioactive compounds and the implication of bioactive compounds in pharmacy. This volume is a useful guide for novice researchers interested in learning research methods to study bioactive compounds. Frontiers in Bioactive Compounds brings edited reviews on the analysis and characterization of natural compounds of medicinal interest. Each volume covers useful information on a variety of natural sources as well as analytical techniques. This series is essential reading for analytical and medicinal chemists as well as professionals involved in natural and pharmaceutical product research and development.

Extracting Bioactive Compounds for Food Products

Extracting Bioactive Compounds for Food Products Book
Author : M. Angela A. Meireles
Publisher : CRC Press
Release : 2008-12-16
ISBN : 9781420062397
Language : En, Es, Fr & De

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Book Description :

The demand for functional foods and neutraceuticals is on the rise, leaving product development companies racing to improve bioactive compound extraction methods – a key component of functional foods and neutraceuticals development. From established processes such as steam distillation to emerging techniques like supercritical fluid technology, Extracting Bioactive Compounds for Food Products: Theory and Applications details the engineering aspects of the processes used to extract bioactive compounds from their food sources. Covers Bioactive Compounds Found in Foods, Cosmetics, and Pharmaceuticals Each well-developed chapter provides the fundamentals of transport phenomena and thermodynamics as they relate to the process described, a state-of-the-art literature review, and replicable case studies of extraction processes. This authoritative reference examines a variety of established and groundbreaking extraction processes including: Steam distillation Low-pressure solvent extraction Liquid-liquid extraction Supercritical and pressurized fluid extraction Adsorption and desorption The acute view of thermodynamic, mass transfer, and economical engineering provided in this book builds a foundation in the processes used to obtain high-quality bioactive extracts and purified compounds. Going beyond the information traditionally found in unit operations reference books, Extracting Bioactive Compounds for Food Products: Theory and Applications demonstrates how to successfully optimize bioactive compound extraction methods and use them to create new and better natural food options.

Bioactive Compounds from Terrestrial Extremophiles

Bioactive Compounds from Terrestrial Extremophiles Book
Author : Lesley-Ann Giddings,David J. Newman
Publisher : Springer
Release : 2014-11-21
ISBN : 3319132601
Language : En, Es, Fr & De

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Book Description :

A discussion of the chemical compounds produced by organisms living under extreme conditions that may have potential as drugs or leads to novel drugs for human use. This SpringerBrief deals with bioactive materials from terrestrial extremophiles.

Bioactive Compounds and Cancer

Bioactive Compounds and Cancer Book
Author : John A. Milner,Donato F. Romagnolo
Publisher : Springer Science & Business Media
Release : 2010-06-25
ISBN : 1607616270
Language : En, Es, Fr & De

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Book Description :

Because of the wealth of new information generated by the scientific community during the last decade on the role of nutrition on cancer risk, this book provides a forum for presentation and discussion of recent scientific data and highlights a set of dietary recommendations. Bioactive Compounds and Cancer presents chapters that highlight laboratory and clinical findings on how selected nutrients function as signaling molecules and, as such, influence cellular behavior and cancer predisposition. This important compendium focuses on understanding the role of nutrition in cancer biology, the molecular action of bioactive food components and xenobiotics on cancer risk, the role of dietary components in cancer prevention and/or treatment, and nutrition education with the most up to date dietary recommendations that may reduce cancer risk. This volume will be of interest to specialized health professionals, clinicians, nurses, basic and clinical researchers, graduate students, and health officials of public and private organizations.