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Biflavanoids

Biflavanoids Book
Author : Shabir Hussain Lone,Mohd Akbar Khuroo
Publisher : Elsevier
Release : 2016-05-19
ISBN : 9780081010303
Language : En, Es, Fr & De

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Book Description :

Biflavanoids are an important class of plant metabolites offering a range of activities, good availability and relatively low toxicity. Long thought to hold possible therapeutic potential, the recent surge in interest for natural product drug discovery has further highlighted the possibility of using them in the discovery of new drugs, and "Biflavanoids: Chemical and Pharmacological Aspects" provides a quick reference to the area in a focused manner, to support and encourage further research. Beginning with a focus on the structural features and occurrence of biflavanoids, Chapter 1 reviews key background information including notes on nomenclature and natural distribution. Chapter 2 then goes on to discuss methods for identification and isolation, with separation and purification using various chromatography methods reviewed, followed by identification via UV spectroscopy, NRM spectroscopy and mass spectrometry. Synthesis is the focus of Chapter 3, with a broad range of synthetic methods outlined, before the book concludes in Chapter 4 by describing the biochemical pharmacology of Biflavanoids and their anticancer, antimicrobial, antiviral, anti-inflammatory and analgesic activity. With its discussion of both the underlying chemistry and biological activity of Biflavanoids, "Biflavanoids: Chemical and Pharmacological Aspects "is a concise guide to this important class of compounds for all those working in the fields of medicinal chemistry and natural products drug discovery. Focused coverage of techniques for the isolation, identification, and synthesis of BiflavanoidsPractical tool for researchers working with these flavonoid compoundsReal-world expertise from the authors provides support for further developments in the growing field of natural product drug discoveryUseful, clear illustrations of key structures throughout the text

Biflavanoids

Biflavanoids Book
Author : Shabir Hussain Lone,Mohd Akbar Khuroo
Publisher : Elsevier
Release : 2016-04-14
ISBN : 0081011903
Language : En, Es, Fr & De

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Book Description :

Biflavanoids are an important class of plant metabolites offering a range of activities, good availability and relatively low toxicity. Long thought to hold possible therapeutic potential, the recent surge in interest for natural product drug discovery has further highlighted the possibility of using them in the discovery of new drugs, and Biflavanoids: Chemical and Pharmacological Aspects provides a quick reference to the area in a focused manner, to support and encourage further research. Beginning with a focus on the structural features and occurrence of biflavanoids, Chapter 1 reviews key background information including notes on nomenclature and natural distribution. Chapter 2 then goes on to discuss methods for identification and isolation, with separation and purification using various chromatography methods reviewed, followed by identification via UV spectroscopy, NRM spectroscopy and mass spectrometry. Synthesis is the focus of Chapter 3, with a broad range of synthetic methods outlined, before the book concludes in Chapter 4 by describing the biochemical pharmacology of Biflavanoids and their anticancer, antimicrobial, antiviral, anti-inflammatory and analgesic activity. With its discussion of both the underlying chemistry and biological activity of Biflavanoids, Biflavanoids: Chemical and Pharmacological Aspects is a concise guide to this important class of compounds for all those working in the fields of medicinal chemistry and natural products drug discovery. Focused coverage of techniques for the isolation, identification, and synthesis of Biflavanoids Practical tool for researchers working with these flavonoid compounds Real-world expertise from the authors provides support for further developments in the growing field of natural product drug discovery Useful, clear illustrations of key structures throughout the text

Studies in the Chemistry of Biflavanoids and 3 benzylideneflavanones

Studies in the Chemistry of Biflavanoids and 3 benzylideneflavanones Book
Author : Teresa M. White,University College, Dublin. Department of Chemistry
Publisher : Unknown
Release : 2000
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Studies in the Chemistry of Biflavanoids and 3 benzylideneflavanones book written by Teresa M. White,University College, Dublin. Department of Chemistry, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biflavonoids

Biflavonoids Book
Author : Andrew G. Mercader,Alicia B. Pomilio
Publisher : Nova Novinka
Release : 2011-11-01
ISBN : 9781621003540
Language : En, Es, Fr & De

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Book Description :

Biflavonoids comprise a group of the flavonoid family that possess a variety of structures and biological activities of high relevance, such as anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antinociceptive, antioxidant, vasodilator and anticlotting. The chemistry of biflavonoids is very important in many fields of research, especially because these compounds are structurally different bioactive molecules with potential for biomedical applications. This book highlights the structural biflavonoid variability, rearrangements and different stereochemistry through about 470 structures distributed in some species of Angiosperms, Gymnosperms, ferns and mosses.

The Distribution of Azoxyglycosides Amino Acids and Biflavanoids in the Order Cycadales Their Taxonomic Phylogenetic and Toxicological Significance

The Distribution of Azoxyglycosides  Amino Acids and Biflavanoids in the Order Cycadales  Their Taxonomic  Phylogenetic and Toxicological Significance Book
Author : Saifuddin Fidahussein Dossaji
Publisher : Unknown
Release : 1974
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Distribution of Azoxyglycosides Amino Acids and Biflavanoids in the Order Cycadales Their Taxonomic Phylogenetic and Toxicological Significance book written by Saifuddin Fidahussein Dossaji, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Synthesis of Novel Biflavanoids

Synthesis of Novel Biflavanoids Book
Author : Mohammed A. Rahman
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Synthesis of Novel Biflavanoids book written by Mohammed A. Rahman, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Black Wattle and Its Utilisation

Black Wattle and Its Utilisation Book
Author : Alan Gordon Brown,Ho Chin Ko
Publisher : Unknown
Release : 1997
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Black Wattle and Its Utilisation book written by Alan Gordon Brown,Ho Chin Ko, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Fortschritte der Chemie organischer Naturstoffe Progress in the Chemistry of Organic Natural Products

Fortschritte der Chemie organischer Naturstoffe   Progress in the Chemistry of Organic Natural Products Book
Author : Anonim
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3709186560
Language : En, Es, Fr & De

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Book Description :

The chemistry of condensed tannins has hitherto represented a relatively unattractive and therefore neglected area of study; one in which the weight of research effort involved is invariably disproportionate to the results achieved, in which the participating schools generally confine their approach to specific molecular species, and in which as yet no consensus has been reached regarding likely precursors. The problems which beset those engaged in this field represent a combined function of the abnormal complexity of the gradational range of oligomers of increasing mass and affinity for substrates which typify most extracts rich in tannins, and the consequent problem of their isolation and purification, the high chirality of tannin oligomers, the need to contend with the phenomenon of dynamic 'rotational isomerism about interflavanoid bonds in the IH n.m.r. spectral interpretation of their derivatives, the lack of precise knowledge regarding the points of bonding at nucleophilic centres, and the obvious limitations of a hitherto predominantly analytical approach. The last of these reflects the need for a general method of synthesis which permits unambiguous proof of both structure and absolute configuration also at higher oligomeric levels. With these objectives in mind we initiated a purely synthetic approach based on the premise that flavan-3,4-diols as source of electrophilic flavanyl-4-carbocations, and flavan-3-0Is as nucleophiles (cf 1,2) represent the prime initiators of a process of repetitive condensation in which the immediate products also represent the sequent nucleophilic substrates.

Structure Synthesis and Biological Activities of Biflavonoids Isolated from Ochna Serrulata Hochst Walp

Structure  Synthesis and Biological Activities of Biflavonoids Isolated from Ochna Serrulata  Hochst   Walp Book
Author : Monica Mbaraka Ndoile
Publisher : Unknown
Release : 2012
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Structure Synthesis and Biological Activities of Biflavonoids Isolated from Ochna Serrulata Hochst Walp book written by Monica Mbaraka Ndoile, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Biochemical Systematics and Ecology

Biochemical Systematics and Ecology Book
Author : Anonim
Publisher : Unknown
Release : 1983
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Biochemical Systematics and Ecology book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

A Synthetic Approach to the Biflavonoids Chamaejasmine and Isochamaejasmine

A Synthetic Approach to the Biflavonoids Chamaejasmine and Isochamaejasmine Book
Author : Verna B. Baron
Publisher : Unknown
Release : 2014
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Biflavonoids form a ubiquitous class of compounds in nature, which are well known for their numerous medicinal benefits. Biflavonoids such as chamaejasmine and isochamaejasmine have been shown to exhibit pharmacological activity such as anitidiabetic, anti-malaria, anti- HIV, anticancer etc. Biflavanones, chamaejasmine and isochamaejasmine are dimers of the flavanone narigenin at the C-3 position, which gives them a rare 3/3" C – C linkage. They are structurally similar in that they both have four stereocenters. The difference between these two compounds is the stereochemistry at the C-2′′ and C-3′′. In this study, installation of each of these stereocenters will be targeted at different stages of the synthesis. Installation of the stereocenters at C-2 and C-3 was achieved through the cyclopropanation of a 2-aryl-2H-chromene, followed by the tin (II) triflate catalyzed rearrangement of the cyclopropane into a gamma-lactone. This gamma-lactone provided the core structure for one of the flavanone units in the targeted biflavonoids, as well as providing the building block for the second flavanone unit. For the construction of the second flavanone unit the gamma-lactone was transformed into a chalcone precursor, which served as the platform for the installation of the other two stereocenters in the biflavonoids. The construction of the chalcone precursor was achieved first through the synthesis of an alpha-benzylidene lactone. Several attempts were made to open this alpha-benzylidene lactone via the addition of an aryllithium, which proved to be a challenge. This problem was resolved through the opening of the alpha-benzylidene lactone via reduction with Red-Al, subsequent formation of an aldehyde, and then addition of the aryllithium to the aldehyde. Successful synthesis of the chalcone precursor was achieved through the oxidation of the product of the aryllithium addition, albeit in a modest yield (43 %). Herein, studies related towards the synthesis of chamaejasmine and isochamaejasmine are presented.

Novel Synthetic Approaches Toward Biflavonoids and Procyanidins

Novel Synthetic Approaches Toward Biflavonoids and Procyanidins Book
Author : Matthew Chilaka Achilonu
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Novel Synthetic Approaches Toward Biflavonoids and Procyanidins book written by Matthew Chilaka Achilonu, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Synthesis of C6 C3 C6 Type Polyphenols

Synthesis of C6 C3 C6 Type Polyphenols Book
Author : Reinier J.J. Nel,University of the Orange Free State
Publisher : Unknown
Release : 1998
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Synthesis of C6 C3 C6 Type Polyphenols book written by Reinier J.J. Nel,University of the Orange Free State, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Plant Polyphenols

Plant Polyphenols Book
Author : Richard W. Hemingway,Peter E. Laks
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461534763
Language : En, Es, Fr & De

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Book Description :

This book was developed from the proceedings of the 2nd North American Tan nin Conference held in Houghton, Michigan, June, 1991. The objective of this con ference was to bring together people with a common interest in plant polyphenols and to promote interdisciplinary interactions that will lead to a bet ter understand ing of the importance of these substances. Another objective of this conference was to extend the 'tannin family' by making special efforts to encourage participation by scientists outside the United States, obtain more coverage of the hydrolyzable tannins, and further broaden the scope of coverage from the initial concentration on forestry and forest products. Com parison of the contents of this book with 'Chemistry and Significance of Condensed Tannins' that resulted from the proceedings of the 1st North American Tannin Conference shows the degree that these objectives were met. In developing the second conference, care was taken to assure that this book extends rather than duplicates the coverage of the first conference. Therefore, the two books should be taken together to obtain an up to date coverage of the broad area of chemistry and significance of plant polyphenols. Our thanks go to the authors who so kindly contributed chapters and so pa tiently responded to our requests. We thank the Conference Assistance Staff of Michigan Technological University for their help in planning and conducting the conference.

Gymnosperms

Gymnosperms Book
Author : Anonim
Publisher : Krishna Prakashan Media
Release : 2021-08-03
ISBN : 9788182830547
Language : En, Es, Fr & De

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Book Description :

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Phytochemicals in Human Health Protection Nutrition and Plant Defense

Phytochemicals in Human Health Protection  Nutrition  and Plant Defense Book
Author : Phytochemical Society of North America,Phytochemical Society of North America. Meeting
Publisher : Springer Science & Business Media
Release : 1999-09-30
ISBN : 9780306462030
Language : En, Es, Fr & De

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Book Description :

Proceedings of the 38th Annual Meeting at the Phytochemical Society of North America on Phytochemicals in Human Health Protection, Nutrition and Plant Defense, held July 26-31, 1998 in Pullman, WA, USA

The Synthesis of Garcinia Biflavonoids

The Synthesis of Garcinia Biflavonoids Book
Author : Brendan M. Fitzpatrick
Publisher : Unknown
Release : 1993
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Synthesis of Garcinia Biflavonoids book written by Brendan M. Fitzpatrick, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Phenolic Metabolism in Plants

Phenolic Metabolism in Plants Book
Author : Ragai K. Ibrahim,Helen A. Stafford
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 1461534305
Language : En, Es, Fr & De

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Book Description :

This volume contains reviews presented at the 31 st annual meeting of the Phytochemical Society of North America, held at Colorado State University in Fort Collins, Colorado on June 22-26, 1991. This symposium, entitled Phenolic Metabolism in Plants, celebrated the origin of this society as the Plant Phenolics Group of North America; the first symposium, entitled Biochemistry of Plant Phenolic Substances, was also held at Fort Collins from August 31 to September 1, 1961. A brief history of the Society is presented in Chapter 12 by Stewart Brown, one of the original founders of the Society. We dedicate this volume to Hans Grisebach, 1926-1990, Professor of Biochemistry at the Biologisches Institut II, Freiburg, Germany, where he headed for many years a laboratory responsible for major advances in the area of phenolic metabolism; this will be self evident from the numerous bibliographical references cited in the literature for papers by his Freiburg group from about 1958 until now, and subsequently by former students and colla borators. His impact on the data reviewed in this volume will testify to this.

Flavonoids and Bioflavonoids

Flavonoids and Bioflavonoids Book
Author : Loránd Farkas,Miklós Gábor,Ferenc Kállay
Publisher : Elsevier Science & Technology
Release : 1977
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Flavonoids and Bioflavonoids book written by Loránd Farkas,Miklós Gábor,Ferenc Kállay, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Aromatic and Heteroaromatic Chemistry

Aromatic and Heteroaromatic Chemistry Book
Author : C W Bird,G W H Cheeseman
Publisher : Royal Society of Chemistry
Release : 2007-10-31
ISBN : 1847555691
Language : En, Es, Fr & De

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Book Description :

Specialist Periodical Reports provide systematic and detailed review coverage of progress in the major areas of chemical research. Written by experts in their specialist fields the series creates a unique service for the active research chemist, supplying regular critical in-depth accounts of progress in particular areas of chemistry. For over 80 years the Royal Society of Chemistry and its predecessor, the Chemical Society, have been publishing reports charting developments in chemistry, which originally took the form of Annual Reports. However, by 1967 the whole spectrum of chemistry could no longer be contained within one volume and the series Specialist Periodical Reports was born. The Annual Reports themselves still existed but were divided into two, and subsequently three, volumes covering Inorganic, Organic and Physical Chemistry. For more general coverage of the highlights in chemistry they remain a 'must'. Since that time the SPR series has altered according to the fluctuating degree of activity in various fields of chemistry. Some titles have remained unchanged, while others have altered their emphasis along with their titles; some have been combined under a new name whereas others have had to be discontinued.