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Basic Fundamentals Of Drug Delivery

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Basic Fundamentals of Drug Delivery

Basic Fundamentals of Drug Delivery Book
Author : Anonim
Publisher : Academic Press
Release : 2018-11-30
ISBN : 0128179104
Language : En, Es, Fr & De

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Book Description :

Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation. Provides up-to-date information on translating the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as orally, parenterally, transdermally or through inhalation Contains extensive references and further reading for course and self-study

Fundamentals of Drug Delivery

Fundamentals of Drug Delivery Book
Author : Heather A. E. Benson,Michael F. Roberts,Adrian C. Williams,Xiaowen Liang
Publisher : Wiley
Release : 2021-06-02
ISBN : 9781119769606
Language : En, Es, Fr & De

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Book Description :

This book overviews key aspects of drug delivery systems including challenges, processes, and future developments. Topics include understanding drug delivery outcomes, nanotechnology in dermal drug delivery, advanced drug delivery systems for biologics, and much more.

Drug Delivery

Drug Delivery Book
Author : Anya M Hillery,Kinam Park
Publisher : CRC Press
Release : 2016-09-15
ISBN : 1482217740
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches. Features: Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation Describes the most recent, emerging, and innovative technologies of drug delivery Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems—crucial considerations in order to achieve licensing approval for these new technologies

Drug Delivery Systems

Drug Delivery Systems Book
Author : Anonim
Publisher : Academic Press
Release : 2019-10-23
ISBN : 0128145080
Language : En, Es, Fr & De

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Book Description :

Drug Delivery Systems examines the current state of the field within pharmaceutical science and concisely explains the history of drug delivery systems, including key developments. The book translates the physicochemical properties of drugs into drug delivery systems administered via various routes, such as oral, parenteral, transdermal and inhalational. Regulatory and product development topics are also explored. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of drug delivery systems within the pharmaceutical sciences industry and research, as well as in chemical engineering. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists. This book provides a comprehensive examination that is suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnologies, and related industries. Provides up-to-date information on how to translate the physicochemical properties of drugs into drug delivery systems Explores how drugs are administered via various routes, such as oral, parenteral, transdermal and inhalational Contains extensive references and further reading for course and self-study

Targeted Drug Delivery Concepts and Design

Targeted Drug Delivery   Concepts and Design Book
Author : Padma V. Devarajan,Sanyog Jain
Publisher : Springer
Release : 2014-12-08
ISBN : 3319113550
Language : En, Es, Fr & De

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Book Description :

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Controlled Drug Delivery

Controlled Drug Delivery Book
Author : Joseph Robinson,Vincent H. L. Lee
Publisher : Informa Health Care
Release : 1987-01-30
ISBN : 9780824775889
Language : En, Es, Fr & De

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Book Description :

Drugs and the pharmaceutical sciences.

The Future of Pharmaceutical Product Development and Research

The Future of Pharmaceutical Product Development and Research Book
Author : Anonim
Publisher : Academic Press
Release : 2020-09-02
ISBN : 0128144556
Language : En, Es, Fr & De

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Book Description :

The Future of Pharmaceutical Product Development and Research examines the latest developments in the pharmaceutical sciences, also highlighting key developments, research and future opportunities. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of the product development phase of drug discovery and drug development. Each chapter covers fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and the pharmaceutical industry. The book focuses on excipients, radiopharmaceuticals, and how manufacturing should be conducted in an environment that follows Good Manufacturing Practice (GMP) guidelines. Researchers and students will find this book to be a comprehensive resource for those working in, and studying, pharmaceuticals, cosmetics, biotechnology, foods and related industries. Provides an overview of practical information for clinical trials Outlines how to ensure an environment that follows Good Manufacturing Practice (GMP) Examines recent developments and suggests future directions for drug production methods and techniques

Drug Delivery in Oncology

Drug Delivery in Oncology Book
Author : Felix Kratz,Peter Senter,Henning Steinhagen
Publisher : John Wiley & Sons
Release : 2013-09-30
ISBN : 3527647759
Language : En, Es, Fr & De

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Book Description :

In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Fundamentals and Applications of Controlled Release Drug Delivery

Fundamentals and Applications of Controlled Release Drug Delivery Book
Author : Juergen Siepmann,Ronald A. Siegel,Michael J. Rathbone
Publisher : Springer Science & Business Media
Release : 2011-12-15
ISBN : 1461408814
Language : En, Es, Fr & De

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Book Description :

This book approaches the subject from a mechanistic perspective that pitches the language at a level that is understandable to those entering the field and who are not familiar with its common phrases or complex terms. It provides a simple encapsulation of concepts and expands on them. In each chapter the basic concept is explained as simply and clearly as possible without a great deal of detail, then in subsequent sections additional material, exceptions to the general rule, examples, etc., is introduced and built up. Such material was generously supplemented with diagrams; conceptually elegant line diagrams in two or three colors. The artwork was well thought out and able to condense the scientific principles into a novel and visually exciting form. The diagrams encourage browsing or draw the reader to salient points. In addition, the technique of highlighting key concepts in a separate box is used throughout each chapter.

Bioadhesive Drug Delivery Systems

Bioadhesive Drug Delivery Systems Book
Author : Edith Mathiowitz,Donald E. Chickering III,Claus-Michael Lehr
Publisher : CRC Press
Release : 1999-07-13
ISBN : 9781420001341
Language : En, Es, Fr & De

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Book Description :

This invaluable reference presents a comprehensive review of the basic methods for characterizing bioadhesive materials and improving vehicle targeting and uptake-offering possibilities for reformulating existing compounds to create new pharmaceuticals at lower development costs. Evaluates the unique carrier characteristics of bioadhesive polymers and their power to enhance localization of delivered agents, local bioavailability, and drug absorption and transport! Written by over 50 international experts and reflecting broad knowledge of both traditional bioadhesive strategies and novel clinical applications, Bioadhesive Drug Delivery Systems discusses mechanical and chemical bonding, polymer-mucus interactions, the effect of surface energy in bioadhesion, polymer hydration, and mucus rheology analyzes biochemical properties of mucus and glycoproteins, cell adhesion molecules, and cellular interaction with two- and three-dimensional surfaces covers microbalances and magnetic force transducers, atomic force microscopy, direct measurements of molecular level adhesions, and methods to measure cell-cell interactions examines bioadhesive carriers, diffusion or penetration enhancers, and lectin-targeted vehicles describes vaginal, nasal, buccal, ocular, and transdermal drug delivery reviews bioadhesive interactions with the mucosal tissues of the eye and mouth, and those in the respiratory, urinary, and gastrointestinal tracts explores issues of product development, clinical testing, and production and more! Amply referenced with over 1400 bibliographic citations, and illustrated with more than 300 drawings, photographs, tables, and display equations, Bioadhesive Drug Delivery Systems serves as a sound basis for innovation in bioadhesive systems and an excellent introduction to the subject. This unique reference is ideal for pharmaceutical scientists and technologists; chemical, polymer, and plastics engineers; biochemists; physical, surface, and colloid chemists; biologists; and upper-level undergraduate and graduate students in these disciplines.

Novel Drug Delivery Systems

Novel Drug Delivery Systems Book
Author : Dulal Krishna Tripathi,Amit Alexander
Publisher : Unknown
Release : 2020-01-27
ISBN : 9789389354188
Language : En, Es, Fr & De

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Book Description :

Download Novel Drug Delivery Systems book written by Dulal Krishna Tripathi,Amit Alexander, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Drug Delivery

Drug Delivery Book
Author : W. Mark Saltzman
Publisher : Oxford University Press
Release : 2001-03-15
ISBN : 0199879753
Language : En, Es, Fr & De

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Book Description :

Synthetic materials are a tremendous potential resource for treating human disease. For the rational design of many of these biomaterials it is necessary to have an understanding of polymer chemistry and polymer physics. Equally important to those two fields is a quantitative understanding of the principles that govern rates of drug transport, reaction, and disappearance in physiological and pathological situations. This book is a synthesis of these principles, providing a working foundation for those in the field of drug delivery. It covers advanced drug delivery and contemporary biomaterials.

Drug Delivery Systems

Drug Delivery Systems Book
Author : Peter Johnson,J. G. Lloyd-Jones
Publisher : John Wiley & Sons
Release : 1987
ISBN : 9783527265589
Language : En, Es, Fr & De

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Book Description :

New drug delivery systems have been the focus of attention for the past 20 years. With a range of international contributions, this book summarizes current knowledge of site-specific, implantable, oral and other noninvasive (i.e. transdermal, nasal and ocular) systems, providing a comprehensive overview of the latest approaches to controlled release technology from both academic and industrial viewpoints. The authors not only present clear and concise accounts of current thinking, but additionally offer the reader some appropriate glimpses into the future, where the combination of drug delivery technology and advancing techniques in molecular biology and genetic engineering holds particular promise.

Novel Drug Delivery Systems

Novel Drug Delivery Systems Book
Author : Yie W. Chien,Bernard E. Cabana,Stanley E. Mares
Publisher : Unknown
Release : 1982-01-01
ISBN : 9780824718312
Language : En, Es, Fr & De

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Book Description :

Download Novel Drug Delivery Systems book written by Yie W. Chien,Bernard E. Cabana,Stanley E. Mares, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Drug Delivery and Targeting

Drug Delivery and Targeting Book
Author : Anya M. Hillery,Andrew W. Lloyd,James Swarbrick
Publisher : CRC Press
Release : 2003-09-02
ISBN : 0203302761
Language : En, Es, Fr & De

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Book Description :

The advances in biotechnology and molecular biology over recent years have resulted in a large number of novel molecules with the potential to revolutionize the treatment and prevention of disease. However, such potential is severely compromised by significant obstacles to delivery of these drugs in vivo. These obstacles are often so great that effective drug delivery and targeting is now recognized as the key to effective development of many therapeutics. Advanced drug delivery and targeting can offer significant advantages to conventional drugs, such as increased efficiency, convenience, and the potential for line extensions and market expansion. An accessible and easy-to-read textbook, Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments, including: *Methods to optimize therapeutic efficacy, and the related commercial implications *Difficulties with drug absorption, unwanted distribution and premature inactivation / elimination *Attempts to minimize toxicity or alter immunogenicity *Methods to achieve rate-controlled drug release and effective drug targeting *Novel and established routes of delivery *Use of new generation technologies such as biosensors, microchips, stimuli-sensitive hydrogels and plasmid-based gene therapy This volume is indispensable for pharmaceutical students, scientists and researchers.

Drug Delivery Nanoparticles Formulation and Characterization

Drug Delivery Nanoparticles Formulation and Characterization Book
Author : Yashwant Pathak,Deepak Thassu
Publisher : CRC Press
Release : 2016-04-19
ISBN : 1420078054
Language : En, Es, Fr & De

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Book Description :

Exploring fundamental concepts, Drug Delivery Nanoparticles Formulation and Characterization presents key aspects of nanoparticulate system development for various therapeutic applications and provides advanced methods used to file for regulatory approval.This comprehensive guide features:Process Analytical Techniques (PAT) used in manufacturing Na

Advanced Drug Delivery

Advanced Drug Delivery Book
Author : Ashim Mitra,Chi H. Lee,Kun Cheng
Publisher : John Wiley & Sons
Release : 2013-08-26
ISBN : 1118662849
Language : En, Es, Fr & De

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Book Description :

Provides both fundamentals and new and emerging applications Advanced Drug Delivery brings readers fully up to datewith the state of the science, presenting the basics, formulationstrategies, and therapeutic applications of advanced drug delivery.The book demonstrates how core concepts of pharmaceutical sciences,chemistry, and molecular biology can be combined and applied inorder to spark novel ideas to design and develop advanced drugdelivery systems for the treatment of a broad range of humandiseases. Advanced Drug Delivery features contributions from aninternational team of pharmaceutical scientists. Chapters reflect athorough review and analysis of the literature as well as theauthors' firsthand experience developing drug delivery systems. Thebook is divided into four parts: Part I, Introduction and Basics of Advanced DrugDelivery, explores physiological barriers, stability,transporters, and biomaterials in drug delivery Part II, Strategies for Advanced Drug Delivery, offerstested and proven strategies for advanced delivery of both smallmolecules and macromolecules Part III, Translational Research of Advanced DrugDelivery, focuses on regulatory considerations andtranslational applications of advanced drug delivery systems forthe treatment of cardiovascular diseases, cancer, sexuallytransmitted diseases, ophthalmic diseases, and brain diseases Part IV, Future Applications of Advanced Drug Delivery inEmerging Research Areas, examines stem cell research,cell-based therapeutics, tissue engineering, and molecularimaging Each chapter provides objectives and assessment questions tohelp readers grasp key concepts and assess their knowledge as theyprogress through the book. Advanced Drug Delivery is recommended for graduates andupper-level undergraduates in the pharmaceutical sciences who needa solid foundation in the basics. It is also recommended forpharmaceutical professionals who want to take advantage of new andemerging applications in advanced drug delivery systems.

Basic Principles of Drug Discovery and Development

Basic Principles of Drug Discovery and Development Book
Author : Benjamin E. Blass
Publisher : Academic Press
Release : 2021-05-25
ISBN : 0128172150
Language : En, Es, Fr & De

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Book Description :

Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields. Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields. This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development. It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process. The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process. Provides a clear explanation of how the pharmaceutical industry works, as well as the complete drug discovery and development process, from obtaining a lead, to testing the bioactivity, to producing the drug, and protecting the intellectual property Includes a new chapter on the discovery and development of biologics (antibodies proteins, antibody/receptor complexes, antibody drug conjugates), a growing and important area of the pharmaceutical industry landscape Features a new section on formulations, including a discussion of IV formulations suitable for human clinical trials, as well as the application of nanotechnology and the use of transdermal patch technology for drug delivery Updated chapter with new case studies includes additional modern examples of drug discovery through high through-put screening, fragment-based drug design, and computational chemistry

Nanotechnology in Drug Delivery

Nanotechnology in Drug Delivery Book
Author : Melgardt M. de Villiers,Pornanong Aramwit,Glen S. Kwon
Publisher : Springer Science & Business Media
Release : 2008-10-29
ISBN : 9780387776682
Language : En, Es, Fr & De

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Book Description :

The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting will also be described.

Drug Delivery

Drug Delivery Book
Author : Binghe Wang,Longqin Hu,Teruna J. Siahaan
Publisher : John Wiley & Sons
Release : 2016-03-09
ISBN : 1118833309
Language : En, Es, Fr & De

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Book Description :

Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all chapters from the previous are retained and updated and several new chapters added to make a more complete resource and reference. • Helps readers understand progress in drug delivery research and applications • Updates and expands coverage to reflect advances in materials for delivery vehicles, drug delivery approaches, and therapeutics • Covers recent developments including transdermal and mucosal delivery, lymphatic system delivery, theranostics • Adds new chapters on nanoparticles, controlled drug release systems, theranostics, protein and peptide drugs, and biologics delivery