Skip to main content

Autophagy In Health And Disease

In Order to Read Online or Download Autophagy In Health And Disease Full eBooks in PDF, EPUB, Tuebl and Mobi you need to create a Free account. Get any books you like and read everywhere you want. Fast Download Speed ~ Commercial & Ad Free. We cannot guarantee that every book is in the library!

Autophagy in Health and Disease

Autophagy in Health and Disease Book
Author : Roberta A. Gottlieb
Publisher : Academic Press
Release : 2012-12-31
ISBN : 0123851025
Language : En, Es, Fr & De

GET BOOK

Book Description :

Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information. Discusses current understanding of the roles of autophagy in health and disease Covers the background of autophagy, the development of tools and therapeutics to measure and modulate autophagy, and autophagy in tissues and disease processes Features an accompanying website with figures and tables

Autophagy in Health and Disease

Autophagy in Health and Disease Book
Author : Kursad Turksen
Publisher : Springer
Release : 2018-10-06
ISBN : 3319981463
Language : En, Es, Fr & De

GET BOOK

Book Description :

This timely volume explores the impact of autophagy in various human diseases, emphasizing the cell biological aspects and focusing on therapeutic approaches to these diseases. The chapters cover autophagy and its potential applications on diseases ranging from obesity, osteoarthritis, pulmonary fibrosis, and inflammation, through ALS, Parkinson's, retinal degeneration, breast cancer, alcoholic liver disease and more. The final chapters round out the book with a discussion of autophagy in drug discovery and 'bench to bedside'. Chapters are contributed by leading authorities and describe the general concepts of autophagy in health and disease, marrying cell biology and pharmacology and covering: studies derived from preclinical experiments, manufacturing considerations,and regulatory requirements pertaining to drug discovery and manufacturing and production. This volume will be useful for basic scientists as well as already practicing clinicians and advanced graduate students.

Autophagy in Health and Disease

Autophagy in Health and Disease Book
Author : Beverly Rothermel,Abhinav Diwan
Publisher : Elsevier
Release : 2021-08-01
ISBN : 012822004X
Language : En, Es, Fr & De

GET BOOK

Book Description :

Autophagy in Health and Disease, Second Edition provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology. The editors expand the coverage from the 1st edition – focused on the cardiovascular system, where research started - to all cell types and organ systems. Starting with the foundational concepts, part I provides an overview of the area, including: history, trajectory of the research field, mechanisms of autophagy, and its regulation. Part I also cover developmental aspects, including: stem cells, embryogenesis, hematopoiesis, and paligenosis. Part II is devoted to applications to several systems in the human body including: Metabolic control and Diabetes, Cardiovascular, Nervous, Immune, Gastrointestinal, and Skeletal. The final chapters provide additional disease considerations, covering cancer, longevity, disease mechanisms, and the therapeutic targeting of Autophagy. This book is invaluable to anyone new to the field, as well as established investigators who are looking for a broader understanding of autophagy outside their specific field of study. Provides a comprehensive overview of the process of autophagy and its impact on human physiology and pathophysiology Extended coverage of the mechanisms mediating autophagy Coverage the role of autophagy in stem cells and iPSCs, as well as the regenerative process of “paligenosis New sections on Metabolic Control and Diabetes include separate chapters covering the liver, adipose, pancreas, and skeletal muscle New section will on the nervous system and neurodegeneration New chapter on cancer and cancer therapeutics

Autophagy in Health and Disease

Autophagy in Health and Disease Book
Author : Anonim
Publisher : Academic Press
Release : 2020-06-30
ISBN : 0128220228
Language : En, Es, Fr & De

GET BOOK

Book Description :

Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in Chronic Lung Disease, Autophagy in motoneuronal disorders, Strategies employed by viruses to manipulate autophagy, and much more. Provides an outstanding panel of recognized experts in the field who discuss the latest in autophagy Includes critical discussions of autophagy in the context of each major human disorder Models autophagy-related human pathologies in lower eukaryotes

Autophagy

Autophagy Book
Author : Pamela Ogden
Publisher : Unknown
Release : 2020-06-06
ISBN : 9781649840042
Language : En, Es, Fr & De

GET BOOK

Book Description :

What is autophagy? Autophagy is the body's way of cleaning out damaged cells, in order to regenerate newer, healthier cells, according to Priya Khorana, PhD, in nutrition education from Columbia University. "Auto" means self and "phagy" means eat. So the literal meaning of autophagy is "self-eating." It's also referred to as "self-devouring." While that may sound like something you never want to happen to your body, it's actually beneficial to your overall health. This is because autophagy is an evolutionary self-preservation mechanism through which the body can remove the dysfunctional cells and recycle parts of them toward cellular repair and cleaning, according to board-certified cardiologist, Dr. Luiza Petre. Petre explains that the purpose of autophagy is to remove debris and self-regulate back to optimal smooth function. "It is recycling and cleaning at the same time, just like hitting a reset button to your body. Plus, it promotes survival and adaptation as a response to various stressors and toxins accumulated in our cells," she adds. What are the benefits of autophagy? The main benefits of autophagy seem to come in the form of anti-aging principles. In fact, Petre says it's best known as the body's way of turning the clock back and creating younger cells. Khorana points out that when our cells are stressed, autophagy is increased in order to protect us, which helps enhance your lifespan. Additionally, registered dietitian, Scott Keatley, RD, CDN, says that in times of starvation, autophagy keeps the body going by breaking down cellular material and reusing it for necessary processes. "Of course this takes energy and cannot continue forever, but it gives us more time to find nourishment," he adds. At the cellular level, Petre says the benefits of autophagy include: removing toxic proteins from the cells that are attributed to neurodegenerative diseases, such as Parkinson's and Alzheimer's disease recycling residual proteins providing energy and building blocks for cells that could still benefit from repair on a larger scale, it prompts regeneration and healthy cells Autophagy is receiving a lot of attention for the role it may play in preventing or treating cancer, too. "Autophagy declines as we age, so this means cells that no longer work or may do harm are allowed to multiply, which is the MO of cancer cells," explains Keatley. While all cancers start from some sort of defective cells, Petre says that the body should recognize and remove those cells, often using autophagic processes. That's why some researchers are looking at the possibility that autophagy may lower the risk of cancer. While there's no scientific evidence to back this up, Petre says some studiesTrusted Source suggest that many cancerous cells can be removed through autophagy. "This is how the body polices the cancer villains," she explains. "Recognizing and destroying what went wrong and triggering the repairing mechanism does contribute to lowering the risk of cancer." Researchers believe that new studies will lead to insight that will help them target autophagy as a therapy for cancer.

Autophagy Cancer Other Pathologies Inflammation Immunity Infection and Aging

Autophagy  Cancer  Other Pathologies  Inflammation  Immunity  Infection  and Aging Book
Author : M. A. Hayat
Publisher : Elsevier
Release : 2013-09-03
ISBN : 0124115144
Language : En, Es, Fr & De

GET BOOK

Book Description :

Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging is a complete, authoritative examination of the role of autophagy in health and disease. Understanding this phenomenon is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and forward thinking, this four-volume work offers a valuable guide to cellular processes while encouraging researchers to explore their potentially important connections. Understanding the role of autophagy is critical, considering its association with numerous biological processes, including cellular development and differentiation, cancer (both antitumor and protumor functions), immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Cell homeostasis is achieved by balancing biosynthesis and cellular turnover. In spite of the increasing importance of autophagy in various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases (e.g., autoimmune disease) remains poorly understood. This work will broaden the knowledge base of academic and clinical professors, post-doctoral fellows, graduate and medical students regarding this vital biological process. Volumes in the Series

Vinexin Regulates Autophagy Through YAP TAZ

Vinexin Regulates Autophagy Through YAP TAZ Book
Author : Rebecca Astrid Frake
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Vinexin Regulates Autophagy Through YAP TAZ book written by Rebecca Astrid Frake, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Scientific American

Scientific American Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Scientific American book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cell Injury

Cell Injury Book
Author : Raphael Carl Lee,Florin Despa,Kimm Jon Hamann,New York Academy of Sciences
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

When cells are damaged, as often occurs during trauma and metabolic stress, a highly evolved cell healing process follows that was designed to enhance cell survival or remove irreparably injured cells. Following injury, cells attempt to seal breaks in their membranes, chaperone removal or refolding of altered proteins, repair damaged DNA, or if necessary commit to programmed cell death. When cell injury is too extensive to permit reparative responses, acute cellular necrosis or apoptosis can result. Understanding injury at the subcellular organelle and molecular levels is essential for development of new therapeutic strategies and for optimal management of injured victims. In this volume, various modes of injury that can occur are described, as well as the basic molecular healing responses and pathways of metabolic survival or death.

Cancer Research

Cancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2009-05
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Cancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Science Medicine

Science   Medicine Book
Author : Anonim
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Science Medicine book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Phagocytic Mechanisms in Health and Disease

Phagocytic Mechanisms in Health and Disease Book
Author : Ralph C. Williams,H. Hugh Fudenberg
Publisher : Unknown
Release : 1972
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Phagocytic Mechanisms in Health and Disease book written by Ralph C. Williams,H. Hugh Fudenberg, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Science

Science Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Science book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Journal of Cell Biology

The Journal of Cell Biology Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

No. 2, pt. 2 of November issue each year from v. 19 (1963)-47 (1970) and v. 55 (1972)- contain the Abstracts of papers presented at the Annual Meeting of the American Society for Cell Biology, 3d (1963)-10th (1970) and 12th (1972)-

Anticancer Research

Anticancer Research Book
Author : Anonim
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Anticancer Research book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Molecular Biology of the Cell

Molecular Biology of the Cell Book
Author : Anonim
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download Molecular Biology of the Cell book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Journal of Neuroscience

The Journal of Neuroscience Book
Author : Anonim
Publisher : Unknown
Release : 2009
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download The Journal of Neuroscience book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

In Vivo

In Vivo Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

GET BOOK

Book Description :

Download In Vivo book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Mitochondrial Signaling in Health and Disease

Mitochondrial Signaling in Health and Disease Book
Author : Sten Orrenius,Lester Packer,Enrique Cadenas
Publisher : CRC Press
Release : 2012-06-20
ISBN : 1439880034
Language : En, Es, Fr & De

GET BOOK

Book Description :

Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis. With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include: Electron transport and energy production Mitochondrial biogenesis and dynamics Mitochondrial signaling Apoptosis and autophagy Pharmacology signaling Epigenetic signaling: mitochondrial methylation and acetylation reactions An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.