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Atkinsons Principles Of Clinical Pharmacology

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Principles of Clinical Pharmacology

Principles of Clinical Pharmacology Book
Author : Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
Publisher : Elsevier
Release : 2011-04-28
ISBN : 9780080466422
Language : En, Es, Fr & De

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Book Description :

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Atkinson s Principles of Clinical Pharmacology

Atkinson s Principles of Clinical Pharmacology Book
Author : Shiew-Mei Huang,Juan J.L. Lertora,Arthur J. Atkinson, Jr.,Paolo Vicini
Publisher : Elsevier
Release : 2021-11-12
ISBN : 0128198699
Language : En, Es, Fr & De

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Book Description :

Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Atkinson s Principles of Clinical Pharmacology

Atkinson s Principles of Clinical Pharmacology Book
Author : Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson, Jr.
Publisher : Academic Press
Release : 2021-10-16
ISBN : 0128198842
Language : En, Es, Fr & De

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Book Description :

Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology Book
Author : Arthur J. Atkinson, Jr.,Shiew-Mei Huang,Juan J.L. Lertora,Sanford P. Markey
Publisher : Academic Press
Release : 2012-09-18
ISBN : 0123854725
Language : En, Es, Fr & De

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Book Description :

Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. The Third Edition has been endorsed by the American Society for Clinical Pharmacology and Therapeutics Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions Offers an expanded regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III

Small Molecule Therapy for Genetic Disease

Small Molecule Therapy for Genetic Disease Book
Author : Jess G. Thoene
Publisher : Cambridge University Press
Release : 2010-08-23
ISBN : 0521517818
Language : En, Es, Fr & De

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Book Description :

Thoene summarises the substantial work that has been accomplished in the treatment of inborn errors of metabolism with simple molecules. This handbook will enable interested clinician scientists to rapidly survey the field, thus ascertaining what has been done as well as future directions for therapeutic research. Its important introductory chapters discuss the infrastructure of the field. The book closely analyses the cofactors used to augment the function of defective enzymes and the compounds that are able to utilise an alternative pathway in order to avoid the consequences of the metabolic block present in the patient. Among other therapies, the authors discuss the use of zinc and tetrathiomolybdate to treat Wilson's disease and the use of cysteamine to treat nephropathic cystinosis.

Geriatric Pharmacology

Geriatric Pharmacology Book
Author : Steven Atkinson
Publisher : Unknown
Release : 2016-11-01
ISBN : 9781683730088
Language : En, Es, Fr & De

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Book Description :

Now in its second edition, Geriatric Pharmacology: The Principles of Practice & Clinical Recommendations is the optimal guide for anyone seeking straightforward, concise and user-friendly information on medication dynamics for older adults. Fully revised and updated, this invaluable resource has become the go-to favorite for healthcare professionals. Here's what you'll find: Learn to manage medication combinations without causing harm How to safely prescribe opioids Avoiding the top 10 most dangerous geriatric drugs Practical guidelines to stop and start prescriptions Drug-drug interaction charts and strategies

Bioequivalence and Statistics in Clinical Pharmacology

Bioequivalence and Statistics in Clinical Pharmacology Book
Author : Scott D. Patterson,Byron Jones
Publisher : CRC Press
Release : 2017-03-27
ISBN : 1315356600
Language : En, Es, Fr & De

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Book Description :

Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and interpret bioequivalence trials; explores when, how, and why these studies are performed as part of drug development; and demonstrates the methods using real world examples. Drawing on knowledge gained directly from working in the pharmaceutical industry, the authors set the stage by describing the general role of statistics. Once the foundation of clinical pharmacology drug development, regulatory applications, and the design and analysis of bioequivalence trials are established, including recent regulatory changes in design and analysis and in particular sample-size adaptation, they move on to related topics in clinical pharmacology involving the use of cross-over designs. These include, but are not limited to, safety studies in Phase I, dose-response trials, drug interaction trials, food-effect and combination trials, QTc and other pharmacodynamic equivalence trials, proof-of-concept trials, dose-proportionality trials, and vaccines trials. This second edition addresses several recent developments in the field, including new chapters on adaptive bioequivalence studies, scaled average bioequivalence testing, and vaccine trials. Purposefully designed to be instantly applicable, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition provides examples of SAS and R code so that the analyses described can be immediately implemented. The authors have made extensive use of the proc mixed procedures available in SAS.

Kidney and Pancreas Transplantation

Kidney and Pancreas Transplantation Book
Author : T. R. Srinivas,Daniel A. Shoskes
Publisher : Springer Science & Business Media
Release : 2010-11-15
ISBN : 1607616424
Language : En, Es, Fr & De

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Book Description :

The transplant physicians and surgeons at Cleveland Clinic have collaborated to produce, Kidney and Pancreas Transplantation: A Practical Guide. This volume is devoted to kidney and pancreas transplantation and is well grounded in scientific principles, quantitative clinical reasoning, clinical pharmacology, tested clinical practices and overall clinical applicability. Also addressed are key aspects in the initiation, maintenance and sustained growth of viable clinical programs in kidney and pancreas transplantation. Kidney and Pancreas Transplantation: A Practical Guide will be of great value to transplant physicians as well as medical and surgical fellows who intend to pursue an interest in transplantation.

Nurse Anesthesia E Book

Nurse Anesthesia   E Book Book
Author : John J. Nagelhout,Karen Plaus
Publisher : Elsevier Health Sciences
Release : 2017-05-27
ISBN : 0323444377
Language : En, Es, Fr & De

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Book Description :

Gain a thorough understanding of nursing anesthesia with the most comprehensive text on the market. Written by leading expert, John Nagelhout, CRNA, PhD, FAAN, and new contributing author Sass Elisha, EdD, CRNA, Nurse Anesthesia, 6th Edition features both scientific principles and evidence-based material. Inside you’ll find a solid introduction to the history, education, and legal issues of nurse anesthetist, its scientific foundations, equipment and monitoring, and preoperative evaluation and preparation of the patient. This new edition includes chapters on patient centered care and cultural competence, additional drugs of interest, blood and blood component therapy, anesthesia management for patients with cardiac devices, anesthesia for robotic surgery, anesthesia for transplant surgery and organ procurement, and physiology and management of acute and chronic pain. Not only a key reference for practicing nurse anesthetists, this bestseller prepares you for certification and today's clinical anesthesia practice. New coverage includes the latest specifics of pharmacokinetics, drug delivery systems, opiate antagonists, and key induction drugs. Updated information on patient safety, monitoring, and pharmacology. Unique! Expert CRNA authors provide the current clinical information that you will use in daily practice. Over 700 tables and boxes highlight the most essential information in a quick, easy-to-reference format. Easy-to-use organization covers basic principles first, and builds on those with individual chapters for each surgical specialty. Updated TJC standards for monitoring and administering moderate sedation/analgesia. NEW! Expanded content includes; non-OR anesthesia, acute and chronic pain management, anesthesia implications of complementary and alternative medicine, robotic surgery, new and less invasive procedures in interventional radiography, implications of modern implanted cardiac devices, and more! NEW! Full-color design and figures clarify difficult concepts and give the text a contemporary look and feel. NEW! Co-author Sass Elisha brings a fresh perspective to this edition.

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics Book
Author : Michelle A. Rudek,Cindy H. Chau,William D. Figg,Howard L. McLeod
Publisher : Springer Science & Business Media
Release : 2014-01-10
ISBN : 1461491355
Language : En, Es, Fr & De

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Book Description :

There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development

Pharmaceutical Medicine and Translational Clinical Research

Pharmaceutical Medicine and Translational Clinical Research Book
Author : Divya Vohora,Gursharan Singh
Publisher : Academic Press
Release : 2017-11-14
ISBN : 0128020989
Language : En, Es, Fr & De

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Book Description :

Pharmaceutical Medicine and Translational Clinical Research covers clinical testing of medicines and the translation of pharmaceutical drug research into new medicines, also focusing on the need to understand the safety profile of medicine and the benefit-risk balance. Pharmacoeconomics and the social impact of healthcare on patients and public health are also featured. It is written in a clear and straightforward manner to enable rapid review and assimilation of complex information and contains reader-friendly features. As a greater understanding of these aspects is critical for students in the areas of pharmaceutical medicine, clinical research, pharmacology and pharmacy, as well as professionals working in the pharmaceutical industry, this book is an ideal resource. Includes detailed coverage of current trends and key topics in pharmaceutical medicine, including biosimilars, biobetters, super generics, and Provides a comprehensive look at current and important aspects of the science and regulation of drug and biologics discovery

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics Book
Author : William D. Figg,Howard L. McLeod
Publisher : Springer Science & Business Media
Release : 2004-03-26
ISBN : 1592597343
Language : En, Es, Fr & De

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Book Description :

Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.

Drugs During Pregnancy and Lactation

Drugs During Pregnancy and Lactation Book
Author : Christof Schaefer,Paul W.J. Peters,Richard K Miller
Publisher : Academic Press
Release : 2014-09-17
ISBN : 0124079016
Language : En, Es, Fr & De

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Book Description :

Drugs During Pregnancy and Lactation, 3rd Edition is a quick and reliable reference for all those working in disciplines related to fertility, pregnancy, lactation, child health and human genetics who prescribe or deliver medicinal products, and to those who evaluate health and safety risks. Each chapter contains twofold information regarding drugs that are appropriate for prescription during pregnancy and an assessment of the risk of a drug when exposure during pregnancy has already occurred. Thoroughly updated with current regulations, references to the latest pharmacological data, and new medicinal products, this edition is a comprehensive resource covering latest knowledge and findings related to drugs during lactation and pregnancy. Provides evidence-based recommendations to help clinicians make appropriate recommendations Uniquely organized and structured according to drug class and treatment indications to offer authoritative clinical content on potential adverse effects Highlights new research developments from primary source about working mechanism of substances that cause developmental disorders

Principles of Rehabilitation Medicine

Principles of Rehabilitation Medicine Book
Author : Raj Mitra
Publisher : McGraw Hill Professional
Release : 2018-10-12
ISBN : 0071793348
Language : En, Es, Fr & De

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Book Description :

A high-yield board review and quick reference for Rehabilitation Medicine Rehabilitation Medicine Rapid Review is written primarily for Physical Medicine and Rehabilitation residents preparing for their board exams, and is also an excellent reference for practicing physicians who need a primer on this rapidly growing specialty. With content organized around the American board of Physical Medicine and Rehabilitation core curriculum, this powerful review is enhanced by more than 500 review questions and answers, and concise, bulleted, high-yield text. Readers will find quick answers to common and infrequent issues encountered in rehabilitation medicine

Pharmacology for Rehabilitation Professionals E Book

Pharmacology for Rehabilitation Professionals   E Book Book
Author : Barbara Gladson
Publisher : Elsevier Health Sciences
Release : 2010-09-15
ISBN : 1437707564
Language : En, Es, Fr & De

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Book Description :

Now fully revised and updated, Dr. Barbara Gladson's Pharmacology for Rehabilitation Professionals, 2nd Edition, remains your best resource for understanding how various drugs affect patients during therapeutic exercise and rehabilitation. Using case studies and engaging activities, it helps you apply essential pharmacology information directly to rehabilitation practice. New chapters, a new reader-friendly design, new artwork, and more enhance the text and bring you up to date with both basic pharmacologic principles as well as the mechanism of action and side effects of drugs commonly seen in rehabilitation practice. Helps you develop effective exercise programs by providing drug/exercise interactions from a pharmacokinetics perspective. You willl clearly see the implications for exercise for each specific condition and medication. Presents case studies in every chapter that demonstrate the effects of various drugs on the diagnosis, prognosis, and interventions in physical therapy, so you can more easily monitor patients for adverse drug effects. Features engaging activities in every chapter, ranging from patient interviews to challenging, real-life questions, helping you retain and apply what you've learned. Encourages you to use the latest research in your clinical decision making with evidence-based content incorporated throughout. Simplifies the complex topic of pharmacokinetics so that you will fully understand how it affects your individual patients and your care plans. Guides you in using the Internet for online drug information with references to specific sites, and when and how to use them to their fullest potential. Discusses lifespan considerations such as age, physical differences, and obesity, as well as the latest information on diabetes and glucose testing. A new chapter on Complementary and Alternative Medicine in Pharmacology covers popular herbal and alternative products used to promote health, as well as herbal remedies used during menopause and in the treatment of cancer, helping you recognize the impact of herbals on your patients' symptoms and response to therapy. A new chapter on Drugs Affecting the Integumentary System discusses skin disorders and their pharmacological treatment, prophylactic and debriding agents, antiseptics, and more. A new chapter on Nutrition and Pharmacology provides current information on vitamins and minerals, enteral and parenteral nutrition, and food and drug interactions -- important topics that affect rehabilitation outcomes. Updated drug information and new drugs are added throughout the text, keeping you up to date with current pharmacological information as it pertains to rehabilitation.

Generation Rx

Generation Rx Book
Author : Greg Critser
Publisher : Houghton Mifflin Harcourt
Release : 2005
ISBN : 9780618393138
Language : En, Es, Fr & De

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Book Description :

A probing look at the state of the nation's health in the midst of a pharmaceutical revolution concludes that America's love affair with drugs is radically transforming the nation, beginning with the youngest generation.

Nano Pharmacokinetics and Theranostics

Nano Pharmacokinetics and Theranostics Book
Author : Nanasaheb D. Thorat,Nitesh Kumar
Publisher : Academic Press
Release : 2021-07-28
ISBN : 0323859828
Language : En, Es, Fr & De

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Book Description :

Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians. Includes contributions from highly qualified scientists, regulatory entities, enterprises and medical practitioners to explain the long and inherently multidisciplinary pathway of nano-pharmacokinetics Describes assessment methods of nano-pharmacokinetics Examines the interface between nanomedicine and pharmacokinetics to diagnose and treat cancer

Primary Care for Women

Primary Care for Women Book
Author : Phyllis Carolyn Leppert,Jeffrey F. Peipert
Publisher : Lippincott Williams & Wilkins
Release : 2004
ISBN : 9780781737906
Language : En, Es, Fr & De

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Book Description :

Thoroughly revised and updated for its Second Edition, this comprehensive, practical reference is an essential resource for obstetrician-gynecologists who are increasingly responsible for primary care and need information on the diagnosis and management of non-gynecologic disorders. It offers all primary care practitioners invaluable guidance on the wide variety of problems unique to women. The book includes chapters on age-specific issues to care for female patients at each stage of life and disease-oriented chapters covering all disorders seen by primary care physicians. Disease-oriented chapters include etiology, differential diagnosis, history, physical examination, laboratory and imaging studies, treatment, and special considerations during pregnancy.

Nurse Anesthesia

Nurse Anesthesia Book
Author : John J. Nagelhout,Karen L. Plaus
Publisher : Elsevier Health Sciences
Release : 2014
ISBN : 1455706124
Language : En, Es, Fr & De

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Book Description :

Written specifically for nurse anesthetists, Nurse Anesthesia, 5th Edition provides comprehensive coverage of both scientific principles and evidence-based practice. It offers a complete overview of anatomy, physiology, pharmacology, and pathophysiology, and offers practical coverage of equipment and anesthesia management. This edition includes updated information on pharmacokinetics, clinical monitoring, drug delivery systems, and complications, and revises chapters on airway management and anesthesia for cardiac surgery. Written by leading nurse anesthesia experts John Nagelhout and Karen Plaus, this perennial bestseller prepares anesthesia students and CRNAs for today's clinical anesthesia practice. Over 650 figures of anatomy, nurse anesthesia procedures, and equipment depict complex concepts and information. An easy-to-use organization covers basic principles first, and builds on those with individual chapters for each surgical specialty. UPDATED references make it quick and simple to find the latest and most important research in the field. Over 700 tables and boxes highlight the most essential information in a quick, easy-to-reference format. Expert CRNA authors provide the current clinical information you'll use in daily practice. UPDATED pharmacology information includes pharmacokinetics, drug delivery systems, opiate antagonists, and key induction drugs. Over 100 NEW photos and illustrations enhance your understanding of difficult anesthesia concepts. UPDATED Airway Management and Anesthesia for Cardiac Surgery chapters are thoroughly revised. NEW coverage includes robotics, screening applications, and non-operating room best practices.

Basic and Clinical Pharmacology 14th Edition

Basic and Clinical Pharmacology 14th Edition Book
Author : Bertram G. Katzung
Publisher : McGraw Hill Professional
Release : 2017-11-30
ISBN : 1259641163
Language : En, Es, Fr & De

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Book Description :

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. The most up-to-date, comprehensive, and authoritative pharmacology text in health medicine—enhanced by a new full-color illustrations A Doody’s Core Title for 2019! Organized to reflect the syllabi in many pharmacology courses and in integrated curricula, Basic & Clinical Pharmacology, Fourteenth Edition covers the important concepts students need to know about the science of pharmacology and its application to clinical practice. Selection of the subject matter and order of its presentation are based on the authors’ many years’ experience in teaching this material to thousands of medical, pharmacy, dental, podiatry, nursing, and other health science students. To be as clinically relevant as possible, the book includes sections that specifically address the clinical choice and use of drugs in patients and the monitoring of their effects, and case studies that introduce clinical problems in many chapters. Presented in full color and enhanced by more than three hundred illustrations (many new to this edition), Basic & Clinical Pharmacology features numerous summary tables and diagrams that encapsulate important information. • Student-acclaimed summary tables conclude each chapter • Everything students need to know about the science of pharmacology and its application to clinical practice • Strong emphasis on drug groups and prototypes • NEW! 100 new drug tables • Includes 330 full-color illustrations, case studies, and chapter-ending summary tables • Organized to reflect the syllabi of pharmacology courses • Descriptions of important new drugs