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Asthma and COPD

Asthma and COPD Book
Author : Peter J. Barnes,Jeffrey M. Drazen,Stephen I. Rennard,Neil C. Thomson
Publisher : Elsevier
Release : 2009-03-19
ISBN : 0080920608
Language : En, Es, Fr & De

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Book Description :

The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. * Each chapter considers Asthma and COPD in side-by-side contrast and comparison – not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management * Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD * Most extensive reference to primary literature on both Asthma and COPD in one source. * Easy-to-read summaries of the latest advances alongside clear illustrations

Asthma COPD and Overlap

Asthma  COPD  and Overlap Book
Author : Jonathan A. Bernstein,Louis-Philippe Boulet,Michael E. Wechsler, MD,MMSc
Publisher : CRC Press
Release : 2018-03-22
ISBN : 1351649051
Language : En, Es, Fr & De

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Book Description :

Using illustrative case examples, this book thoroughly reviews similarities and differences between asthma, chronic obstructive pulmonary disease (COPD) and the overlap syndrome. It is important to highlight the distinctions because these commonly encountered conditions in respiratory and primary care share many similarities but have important differences often mistaken for each other. This can have serious implications for treatment, particularly as new treatments are targeted at specific phenotypes of the diseases. This practical guide shows how to distinguish between the diseases on a pathological and clinical basis so that appropriate management and treatment may be pursued.

New Drugs and Targets for Asthma and COPD

New Drugs and Targets for Asthma and COPD Book
Author : T.T. Hansel,P.J. Barnes
Publisher : Karger Medical and Scientific Publishers
Release : 2010-08-31
ISBN : 3805595670
Language : En, Es, Fr & De

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Book Description :

Asthma, allergy and chronic obstructive lung disease are common throughout the world and are increasing in incidence, particularly in the developing world. This volume provides a state-of-the-art account of the identification of new targets and the development of new therapies for these conditions. Some 40 chapters by clinical academics and senior members of the pharmaceutical industry detail the latest breakthroughs in research and development. In asthma, a promising approach is the use of therapy directed against specific Th2 responses through biological antagonists of IL-5, IL-4 and IL-13. There have also been major advances in our understanding of innate immune responses to pathogen-associated molecular patterns, and in the area of Toll-like receptors. Up to date and comprehensive, this book will be of particular relevance to those working in the pharmaceutical industry (in preclinical research and clinical development), to academic researchers in the field of respiratory medicine, and to respiratory health care specialists.

COPD Clinical Perspectives

COPD Clinical Perspectives Book
Author : Ralph J. Panos
Publisher : BoD – Books on Demand
Release : 2014-07-16
ISBN : 953511624X
Language : En, Es, Fr & De

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Book Description :

Chronic Obstructive Pulmonary Disease (COPD) is an increasingly recognized cause of morbidity and mortality. Over the next 10 years, deaths due to COPD are expected to increase by 30% and, by 2030, COPD is estimated to be the third leading cause of death worldwide. Research into the pathophysiology and management of COPD over the past decade has progressed immensely with greater understanding of the global burden of COPD, its pathophysiology, better understanding of the multisystemic manifestations of COPD, and, most importantly, novel and more effective therapeutic strategies. This volume brings together an international group of experts in COPD to provide in depth reviews of clinical perspectives into COPD. Topics range from the diagnosis of airflow limitation by spirometry; distinguishing COPD from another common obstructive lung disease, asthma; alpha-1-antitrypsin deficiency and opportunities to diagnose this most common hereditary cause of COPD and as a paradigm for the development of novel therapeutics; the overlap syndrome - the concurrence of two epidemic disorders: COPD and obstructive sleep apnea; and pulmonary rehabilitation, one of the most effective treatments for COPD.

Pharmacology of Asthma

Pharmacology of Asthma Book
Author : Clive P. Page,Peter J. Barnes
Publisher : Springer
Release : 1991-02-28
ISBN : 9783540528395
Language : En, Es, Fr & De

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Book Description :

This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has changed dramatically in recent years, and much of this new information is brought together in this volume written by inter nationally recognised authorities. The aim of the book is to review in depth the changing concepts of inflammatory processes in asthma and to discuss the implications for research of this common chronic disease. Many of the advances in and future therapy our understanding of asthma have originated from a pharmacological approach, and this volume highlights the promising new options for pharma cological intervention. It is hoped this book will be invaluable for research scientists and clinic ians involved in asthma research and will be a major reference resource for chest physicians and those involved in the development of novel pharmaceu tical entities. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this growing area. c.P. PAGE P.l. BARNES Contents CHAPTER 1 The Pathology of Asthma: An Overview L.A. LAmNEN and A. LAmNEN. With 10 Figures ...................... 1 A. Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 1 . . . . . . . . . . . . . . . B. Methods to Investigate the Pathology of Human Asthma ............ 1 C. Bronchial Epithelium and Inflammatory Cells in Asthmatic Patients Between Attacks ........................... 2 I. Mast Cells . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .. . . 4 . . . . . . . . . . . . . . II. Eosinophils ............................................... 7 III. Neutrophils.............................................. 10 D. Bronchial Epithelial Inflammation During an Asthma Attack. . . . . .. . 10 E. Epithelial Regeneration .... . . . . . . . . . . . . . . . . . . . . . . .. . . 12 . . . . . . . . .

Asthma and COPD

Asthma and COPD Book
Author : Peter J. Barnes,Jeffrey M. Drazen,Stephen I. Rennard,Neil C. Thomson
Publisher : Academic Press
Release : 2008-10-30
ISBN : 0123740010
Language : En, Es, Fr & De

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Book Description :

The Second Edition of Asthma and COPD: Basic Mechanisms and Clinical Management continues to provide a unique and authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it continues to be a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments. Each chapter considers Asthma and COPD in side-by-side contrast and comparison - not in isolation - in the context of mechanism, triggers, assessments, therapies, and clinical management Presents the latest and most comprehensive understandings of the mechanisms of inflammation in both Asthma and COPD Most extensive reference to primary literature on both Asthma and COPD in one source. Easy-to-read summaries of the latest advances alongside clear illustrations

The Global Impact of Respiratory Disease

  The   Global Impact of Respiratory Disease Book
Author : Darcy D. Marciniuk,Dean E. Schraufnagel
Publisher : Unknown
Release : 2017
ISBN : 9781849840880
Language : En, Es, Fr & De

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Book Description :

Download The Global Impact of Respiratory Disease book written by Darcy D. Marciniuk,Dean E. Schraufnagel, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

COPD An Issue of Clinics in Chest Medicine

COPD  An Issue of Clinics in Chest Medicine  Book
Author : Peter J Barnes
Publisher : Elsevier Health Sciences
Release : 2014-02-15
ISBN : 0323260918
Language : En, Es, Fr & De

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Book Description :

This issue of Clinics in Chest Medicine is Guest Edited by Peter J. Barnes FRS, FMedSci from Imperial College London and will fosus on COPD. Article topics include epidemiology, pathophysiology, cellular and molecular mechanisms and comorbidities of COPD, diagnosis and phenotype of COPD, pulmonary rehabilitation, asthma and COPD, biomarkers, bronchodilators, non invasive ventialtion, and new drug therapies.

Lung Function

Lung Function Book
Author : John E. Cotes,Robert L. Maynard,Sarah J. Pearce,Benoit B. Nemery,Peter D. Wagner,Brendan G. Cooper
Publisher : John Wiley & Sons
Release : 2020-05-11
ISBN : 1118597354
Language : En, Es, Fr & De

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Book Description :

The seventh edition of the most authoritative and comprehensive book published on lung function, now completely revised and restructured Lung function assessment is the central pillar of respiratory diagnosis. Most hospitals have lung function laboratories where patients are tested with a variety of physiological methods. The tests and techniques used are specialized and utilize the expertise of respiratory physicians, physiologists, and technicians. This new edition of the classic text on lung function is a theoretical textbook and practical manual in one that gives a comprehensive account of lung function and its assessment in healthy persons and those with all types of respiratory disorder, against a background of respiratory, exercise, and environmental physiology. It incorporates the technical and methodological recommendations for lung function testing of the American Thoracic Society and European Respiratory Society. Cotes' Lung Function, 7th Edition is filled with chapters covering respiratory surveys, respiratory muscles, neonatal assessment, exercise, sleep, high altitude, hyperbaria, the effects of cold and heat, respirable dusts, fumes and vapors, anesthesia, surgery, and respiratory rehabilitation. It also offers a compendium of lung function in selected individual diseases and is filled with more diagrams and illustrative cases than previous editions. The only text to cover lung function assessment from first principles including methodology, reference values, and interpretation Completely re-written in a contemporary style—includes user-friendly equations and more diagrams Covers the latest advances in the treatment of lung function, including a stronger clinical and practical bias and more on new techniques and equipment Keeps mathematical treatments to a minimum Cotes' Lung Function is an ideal guide for respiratory physicians and surgeons, staff of lung function laboratories, and others who have a professional interest in the function of the lungs at rest or on exercise and how it may be assessed. Physiologists, anthropologists, pediatricians, anesthetists, occupational physicians, explorers, epidemiologists, and respiratory nurses should also find the book useful.

Inflammatory Mechanisms in Asthma

Inflammatory Mechanisms in Asthma Book
Author : Stephen Holgate
Publisher : Routledge
Release : 2018-12-07
ISBN : 1351438492
Language : En, Es, Fr & De

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Book Description :

This timely volume brings together the latest basic and clinical insights on the cellular and mediator mechanisms involved in the induction and persistence of airway dysfunction of asthma by over 90 experts in the field-paving the way for developing novel and more effective antiinflammatory therapeutic agents and strategies. Furnishing a comprehensive and up-to-date view of the expanding and interrelated components underlying asthma pathogenesis, Inflammatory Mechanisms in Asthma describes how evidence on airway inflammation is obtained with invasive and noninvasive procedures, such as bronchoalveolar lavage and sputum analysis reviews the complex interactions of inflammatory cells that contribute to chronic inflammation and bronchial hyperreactivity, including eosinophils, basophils, neutrophils, fibroblasts, epithelial cells, and macrophages considers mast cells, cytokines, neural factors, leukotrienes, kinins, and other mediators that regulate the development, establishment, or resolution of asthma exacerbations presents new information suggesting that airway changes in asthma can lead to remodeling or airway fibrosis and more! Enhanced with over 4700 references, tables, drawings, and photographs, this compelling investigation into the pathophysiology of asthma is an indispensable resource for pulmonologists, physiologists, immunologists, allergists, epidemiologists, biochemists, molecular biologists, and graduate and medical school students in these disciplines.

Clinical Management of Chronic Obstructive Pulmonary Disease

Clinical Management of Chronic Obstructive Pulmonary Disease Book
Author : William MacNee,Richard L. ZuWallack,Joseph Keenan
Publisher : Professional Communications
Release : 2009-05
ISBN : 1932610502
Language : En, Es, Fr & De

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Book Description :

This book reviews the differential diagnosis, pathogenesis, and clinical management of COPD, plus specific treatment regimens, treatment of acute exacerbations, goals of therapy, prognosis, nonpharmacologic management, and smoking cessation. A main focus of the text is pharmacologic treatment of COPD, with results of major clinical trials for COPD medication agents reviewed. Pertinent clinical issues encountered in the management of COPD are discussed. Relevant consensus statements and guidelines on treatment are reviewed and critiqued.

Genetics of Asthma and Chronic Obstructive Pulmonary Disease

Genetics of Asthma and Chronic Obstructive Pulmonary Disease Book
Author : Dirkje S. Postma,Scott T. Weiss
Publisher : CRC Press
Release : 2006-09-06
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Responding to the substantial growth that has taken place in the field over the past decade, this reference provides an in-depth overview of current thought on the genetics and genomics of asthma and COPD in relation to their pathogenesis and treatment. With contributions by an esteemed team of international authorities on the topic, this source spans the latest developments in the utilization of microarray techniques, linkage and association studies, mapping strategies, comparative genetics, microarray techniques, proteomics, and pharmacogenomics.

The Saint Chopra Guide to Inpatient Medicine

The Saint Chopra Guide to Inpatient Medicine Book
Author : Sanjay Saint,Vineet Chopra
Publisher : Oxford University Press
Release : 2018-11-09
ISBN : 0190862823
Language : En, Es, Fr & De

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Book Description :

THE DEFINITIVE GUIDE TO INPATIENT MEDICINE, UPDATED AND EXPANDED FOR A NEW GENERATION OF STUDENTS AND PRACTITIONERS A long-awaited update to the acclaimed Saint-Frances Guides, the Saint-Chopra Guide to Inpatient Medicine is the definitive practical manual for learning and practicing inpatient medicine. Its end-to-end coverage of the specialty focuses on both commonly encountered problems and best practices for navigating them, all in a portable and user-friendly format. Composed of lists, flowcharts, and "hot key" clinical insights based on the authors' decades of experience, the Saint-Chopra Guide ushers clinicians through common clinical scenarios from admission to differential diagnosis and clinical plan. It will be an invaluable addition -- and safety net -- to the repertoire of trainees, clinicians, and practicing hospitalists at any stage of their career.

A COPD Primer

A COPD Primer Book
Author : Ralph Panos,William Eschenbacher
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2015-01-01
ISBN : 311046800X
Language : En, Es, Fr & De

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Book Description :

In 2012 we received a grant from the Veterans Health Administration Office of Specialty Care entitled, “Patient-Centered Model for the Management of Chronic Obstructive Pulmonary Disease.” The grant’s goals were to enhance the recognition and diagnosis of COPD and implement a Patient-Centered Model for the Management of COPD. As the work on that proposal progressed, we realized that providers did not have an up-to-date, comprehensive, easily read, “how to” manual for the management of COPD despite all the advances in COPD care that have occurred over the past 5 years. Consensus documents such as the VA-DOD Guidelines were abbreviated summaries that were rarely used. From those discussions, the concept for this volume, a COPD Primer, developed. The goal was to develop a practical book that concisely presented COPD to providers with sufficient background and explanation of the physiologic and scientific rationale for various management strategies without becoming an esoteric academic work. We hope that this COPD Primer has achieved that goal and will be a useful, practical text for practitioners and medical trainees alike. The COPD Primer begins with an examination of what COPD is; it is really a syndrome, a constellation of historical features and clinical, physiologic, and radiographic findings. However, those elements come together in many different ways to create multiple different COPD phenotypes that are only now being recognized and used to define specific management strategies. COPD research has progressed beyond the simple classification of “blue bloaters” and “pink puffers.” Next, the epidemiology and economic consequences of COPD are reviewed. Bill Eschenbacher presents an approach to the patient with respiratory symptoms with detailed discussions of pulmonary function testing and how airflow limitation/obstruction is identified by spirometry and the use of lung imaging to identify individuals with COPD. Michael Borchers and Gregory Motz summarize current evidence implicating genetics, proteolytic imbalance, oxidative stress, inflammation, occupational and environmental exposures, and innate and adaptive immune function in the pathogenesis of COPD and the implication of these findings to future treatments. The single most important intervention in the prevention and treatment of COPD is smoking cessation. Shari Altum, Katherine Butler, and Rachel Juran present a practical approach to smoking cessation utilizing motivational interviewing in combination with pharmacologic interventions. Then, they expand upon these concepts to provide practitioners with convenient, realistic suggestions to encourage patient self-management in all aspects of COPD care and overall health. Ahsan Zafar reviews the natural history, recently described COPD phenotypes, and gender differences that clearly illustrate the broad spectrum of disease that comprises the term, COPD. The cover illustration highlights Dr. Zafar’s creative and artistic talents. The extensive nonpulmonary aspects of COPD are reviewed by Ralph Panos in an examination of COPD’s multi-organ manifestations. Next, the effect of COPD on sleep and the overlap syndrome, the concurrence of COPD and obstructive sleep apnea, and its consequences are presented. Jean Elwing examines the effect of COPD on the pulmonary vasculature with a detailed discussion of the evaluation and management of pulmonary hypertension associated with COPD. COPD’s effects on psychosocial functioning and familial interactions are presented by Mary Panos and Ralph Panos. The focus of the Primer then shifts from manifestations to treatment with a discussion of stable COPD management. With the current plethora of devices for delivering respiratory medications, it is difficult for both patients and providers to sustain knowledge of their proper use. Aaron Mulhall presents a practical guide to correct inhaler use that reviews all the current devices. Folarin Sogbetun then reviews the management of outpatient COPD exacerbations and Nishant Gupta discusses the approach to the patient hospitalized with COPD. Because patients with COPD often see multiple subspecialty physicians in addition to their primary care providers, interdisciplinary communication and coordination of care is essential for their management; Sara Krzywkowski-Mohn reviews the interactions between primary and specialty care for the patient with COPD with suggestions for improved communication and care coordination. Finally, advance care planning including palliative care and hospice is reviewed with a discussion of how end stage COPD affects not only the patient but also their family and social network. This COPD Primer incorporates the knowledge that we have learned over the past several years during the development and implementation of a patient-centered model for the management of COPD. It was written with the explicit goal of assisting both the practicing provider and medical trainee in the care of patients with COPD.

Disease Control Priorities in Developing Countries

Disease Control Priorities in Developing Countries Book
Author : Dean T. Jamison,Joel G. Breman,Anthony R. Measham,George Alleyne,Mariam Claeson,David B. Evans,Prabhat Jha,Anne Mills,Philip Musgrove
Publisher : World Bank Publications
Release : 2006-04-02
ISBN : 0821361805
Language : En, Es, Fr & De

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Book Description :

Based on careful analysis of burden of disease and the costs ofinterventions, this second edition of 'Disease Control Priorities in Developing Countries, 2nd edition' highlights achievable priorities; measures progresstoward providing efficient, equitable care; promotes cost-effectiveinterventions to targeted populations; and encourages integrated effortsto optimize health. Nearly 500 experts - scientists, epidemiologists, health economists,academicians, and public health practitioners - from around the worldcontributed to the data sources and methodologies, and identifiedchallenges and priorities, resulting in this integrated, comprehensivereference volume on the state of health in developing countries.

Emergency Department Critical Care

Emergency Department Critical Care Book
Author : Joseph R. Shiber,Scott D. Weingart
Publisher : Springer Nature
Release : 2020-06-19
ISBN : 3030287947
Language : En, Es, Fr & De

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Book Description :

This comprehensive book provides practical guidance on the care of the critical patient in the emergency department. It focuses on the ED physician or provider working in a community hospital where, absent the consulting specialists found in a large academic center, the provider must evaluate and stabilize critically ill and injured patients alone. Structured in an easily accessible format, chapters present fundamental information in tables, bullet points, and flow diagrams. Emergency medicine scenarios covered across 38 chapters include acute respiratory failure, spinal cord Injuries, seizures and status epilepticus, care of the newborn, and end-of-life care. Written by experts in the field, Emergency Department Critical Care is an essential resource for practicing emergency physicians and trainees, internists and family physicians, advance practice nurses, and physician’s assistants who provide care in emergency departments and urgent care centers.

Pathy s Principles and Practice of Geriatric Medicine

Pathy s Principles and Practice of Geriatric Medicine Book
Author : Alan J. Sinclair,John E. Morley,Bruno Vellas
Publisher : John Wiley & Sons
Release : 2012-03-13
ISBN : 1119954142
Language : En, Es, Fr & De

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Book Description :

This new edition of the comprehensive and renowned textbook Principles and Practice of Geriatric Medicine offers a fully revised and updated review of geriatric medicine. It covers the full spectrum of the subject, features 41 new chapters, and provides up-to-date, evidence-based, and practical information about the varied medical problems of ageing citizens. The three editors, from UK, USA and France, have ensured that updated chapters provide a global perspective of geriatric medicine, as well as reflect the changes in treatment options and medical conditions which have emerged since publication of the 4th edition in 2006. The book includes expanded sections on acute stroke, dementia, cardiovascular disease, and respiratory diseases, and features a new section on end-of-life care. In the tradition of previous editions, this all-encompassing text continues to be a must-have text for all clinicians who deal with older people, particularly geriatric medical specialists, gerontologists, researchers, and general practitioners. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store. Praise for the 4th edition: "...an excellent reference for learners at all clinical and preclinical levels and a useful contribution to the geriatric medical literature." —Journal of the American Medical Association, November 2006 5th edition selected for 2012 Edition of Doody's Core TitlesTM

Pharmacology and Therapeutics of Asthma and COPD

Pharmacology and Therapeutics of Asthma and COPD Book
Author : Clive P. Page,Peter J. Barnes
Publisher : Springer
Release : 2017-02-06
ISBN : 3319521756
Language : En, Es, Fr & De

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Book Description :

The present volume is supposed to be a major reference resource for chest physicians and those involved in the development of novel pharmaceutical entities for these diseases. Internationally recognized authorities review the most important new information on the advances in our understanding of the pathogenesis and treatment of these diseases, including the substantial advances in the topical delivery of inhaled medicines. Each chapter is extensively referenced, generously illustrated with clear diagrams and photographs, and represents a state-of-the-art review of this important area of respiratory medicine.

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases

A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases Book
Author : Institute of Medicine,Board on Population Health and Public Health Practice,Committee on a National Surveillance System for Cardiovascular and Select Chronic Diseases
Publisher : National Academies Press
Release : 2011-08-26
ISBN : 0309212197
Language : En, Es, Fr & De

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Book Description :

Chronic diseases are common and costly, yet they are also among the most preventable health problems. Comprehensive and accurate disease surveillance systems are needed to implement successful efforts which will reduce the burden of chronic diseases on the U.S. population. A number of sources of surveillance data--including population surveys, cohort studies, disease registries, administrative health data, and vital statistics--contribute critical information about chronic disease. But no central surveillance system provides the information needed to analyze how chronic disease impacts the U.S. population, to identify public health priorities, or to track the progress of preventive efforts. A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases outlines a conceptual framework for building a national chronic disease surveillance system focused primarily on cardiovascular and chronic lung diseases. This system should be capable of providing data on disparities in incidence and prevalence of the diseases by race, ethnicity, socioeconomic status, and geographic region, along with data on disease risk factors, clinical care delivery, and functional health outcomes. This coordinated surveillance system is needed to integrate and expand existing information across the multiple levels of decision making in order to generate actionable, timely knowledge for a range of stakeholders at the local, state or regional, and national levels. The recommendations presented in A Nationwide Framework for Surveillance of Cardiovascular and Chronic Lung Diseases focus on data collection, resource allocation, monitoring activities, and implementation. The report also recommends that systems evolve along with new knowledge about emerging risk factors, advancing technologies, and new understanding of the basis for disease. This report will inform decision-making among federal health agencies, especially the Department of Health and Human Services; public health and clinical practitioners; non-governmental organizations; and policy makers, among others.