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Artificial Intelligence And Deep Learning In Pathology

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Artificial Intelligence and Deep Learning in Pathology

Artificial Intelligence and Deep Learning in Pathology Book
Author : Stanley Cohen
Publisher : Elsevier Health Sciences
Release : 2020-06-02
ISBN : 0323675379
Language : En, Es, Fr & De

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Book Description :

Recent advances in computational algorithms, along with the advent of whole slide imaging as a platform for embedding artificial intelligence (AI), are transforming pattern recognition and image interpretation for diagnosis and prognosis. Yet most pathologists have just a passing knowledge of data mining, machine learning, and AI, and little exposure to the vast potential of these powerful new tools for medicine in general and pathology in particular. In Artificial Intelligence and Deep Learning in Pathology, Dr. Stanley Cohen covers the nuts and bolts of all aspects of machine learning, up to and including AI, bringing familiarity and understanding to pathologists at all levels of experience. Focuses heavily on applications in medicine, especially pathology, making unfamiliar material accessible and avoiding complex mathematics whenever possible. Covers digital pathology as a platform for primary diagnosis and augmentation via deep learning, whole slide imaging for 2D and 3D analysis, and general principles of image analysis and deep learning. Discusses and explains recent accomplishments such as algorithms used to diagnose skin cancer from photographs, AI-based platforms developed to identify lesions of the retina, using computer vision to interpret electrocardiograms, identifying mitoses in cancer using learning algorithms vs. signal processing algorithms, and many more.

Artificial Intelligence and Machine Learning for Digital Pathology

Artificial Intelligence and Machine Learning for Digital Pathology Book
Author : Andreas Holzinger,Randy Goebel,Michael Mengel,Heimo Müller
Publisher : Springer Nature
Release : 2020-06-24
ISBN : 3030504026
Language : En, Es, Fr & De

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Book Description :

Data driven Artificial Intelligence (AI) and Machine Learning (ML) in digital pathology, radiology, and dermatology is very promising. In specific cases, for example, Deep Learning (DL), even exceeding human performance. However, in the context of medicine it is important for a human expert to verify the outcome. Consequently, there is a need for transparency and re-traceability of state-of-the-art solutions to make them usable for ethical responsible medical decision support. Moreover, big data is required for training, covering a wide spectrum of a variety of human diseases in different organ systems. These data sets must meet top-quality and regulatory criteria and must be well annotated for ML at patient-, sample-, and image-level. Here biobanks play a central and future role in providing large collections of high-quality, well-annotated samples and data. The main challenges are finding biobanks containing ‘‘fit-for-purpose’’ samples, providing quality related meta-data, gaining access to standardized medical data and annotations, and mass scanning of whole slides including efficient data management solutions.

Artificial Intelligence and Deep Learning in Pathology

Artificial Intelligence and Deep Learning in Pathology Book
Author : Stanley Cohen
Publisher : Elsevier
Release : 2020-06
ISBN : 9780323675383
Language : En, Es, Fr & De

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Book Description :

Recent advances in computational algorithms, along with the advent of whole slide imaging as a platform for embedding artificial intelligence (AI), are transforming pattern recognition and image interpretation for diagnosis and prognosis. Yet most pathologists have just a passing knowledge of data mining, machine learning, and AI, and little exposure to the vast potential of these powerful new tools for medicine in general and pathology in particular. In Artificial Intelligence and Deep Learning in Pathology, Dr. Stanley Cohen covers the nuts and bolts of all aspects of machine learning, up to and including AI, bringing familiarity and understanding to pathologists at all levels of experience. Focuses heavily on applications in medicine, especially pathology, making unfamiliar material accessible and avoiding complex mathematics whenever possible. Covers digital pathology as a platform for primary diagnosis and augmentation via deep learning, whole slide imaging for 2D and 3D analysis, and general principles of image analysis and deep learning. Discusses and explains recent accomplishments such as algorithms used to diagnose skin cancer from photographs, AI-based platforms developed to identify lesions of the retina, using computer vision to interpret electrocardiograms, identifying mitoses in cancer using learning algorithms vs. signal processing algorithms, and many more.

Digital Pathology

Digital Pathology Book
Author : Liron Pantanowitz,Anil V. Parwani
Publisher : Unknown
Release : 2017
ISBN : 9780891896104
Language : En, Es, Fr & De

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Book Description :

The definitive, complete reference of digital pathology! An extraordinarily comprehensive and complete book for individuals with anything from minimal knowledge to deep, accomplished experience in digital pathology. Easy to read and plainly written, Digital Pathology examines the history and technological evolution of digital pathology, from the birth of scanning technology and telepathology to three-dimensional imaging on large multi-touch displays and computer aided diagnosis. A must-have book for anyone wishing to learn more about and work in this exciting and critical information environment including pathologists, laboratory professionals, students and any other medical practitioners with a particular interest in the history and future of digital pathology. It can also be a useful reference for anyone, medical or non-medical, who have an interest in learning more about the field. Digital pathology is truly a game changer, and this book is a crucial tool for anyone wishing to know more. Subjects discussed in depth include: Static digital imaging; basics and clinical use. Digital imaging processes. Telepathology. While slide imaging. Clinical applications of whole slide imaging. Digital pathology for educational, quality improvement, research and other settings. Forensic digital imaging.

Deep Medicine

Deep Medicine Book
Author : Eric Topol
Publisher : Basic Books
Release : 2019-03-12
ISBN : 1541644646
Language : En, Es, Fr & De

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Book Description :

One of America's top doctors reveals how AI will empower physicians and revolutionize patient care Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard. Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine better, for all the humans involved.

Medical Imaging

Medical Imaging Book
Author : K.C. Santosh,Sameer Antani,DS Guru,Nilanjan Dey
Publisher : CRC Press
Release : 2019-08-20
ISBN : 0429642490
Language : En, Es, Fr & De

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Book Description :

The book discusses varied topics pertaining to advanced or up-to-date techniques in medical imaging using artificial intelligence (AI), image recognition (IR) and machine learning (ML) algorithms/techniques. Further, coverage includes analysis of chest radiographs (chest x-rays) via stacked generalization models, TB type detection using slice separation approach, brain tumor image segmentation via deep learning, mammogram mass separation, epileptic seizures, breast ultrasound images, knee joint x-ray images, bone fracture detection and labeling, and diabetic retinopathy. It also reviews 3D imaging in biomedical applications and pathological medical imaging.

Whole Slide Imaging

Whole Slide Imaging Book
Author : Anil V. Parwani
Publisher : Springer Nature
Release : 2021-10-29
ISBN : 3030833321
Language : En, Es, Fr & De

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Book Description :

This book provides up-to-date and practical knowledge in all aspects of whole slide imaging (WSI) by experts in the field. This includes a historical perspective on the evolution of this technology, technical aspects of making a great whole slide image, the various applications of whole slide imaging and future applications using WSI for computer-aided diagnosis The goal is to provide practical knowledge and address knowledge gaps in this emerging field. This book is unique because it addresses an emerging area in pathology for which currently there is only limited information about the practical aspects of deploying this technology. For example, there are no established selection criteria for choosing new scanners and a knowledge base with the key information. The authors of the various chapters have years of real-world experience in selecting and implementing WSI solutions in various aspects of pathology practice. This text also discusses practical tips and pearls to address the selection of a WSI vendor, technology details, implementing this technology and provide an overview of its everyday uses in all areas of pathology. Chapters include important information on how to integrate digital slides with laboratory information system and how to streamline the “digital workflow” with the intent of saving time, saving money, reducing errors, improving efficiency and accuracy, and ultimately benefiting patient outcomes. Whole Slide Imaging: Current Applications and Future Directions is designed to present a comprehensive and state-of the-art approach to WSI within the broad area of digital pathology. It aims to give the readers a look at WSI with a deeper lens and also envision the future of pathology imaging as it pertains to WSI and associated digital innovations.

Digital Pathology

Digital Pathology Book
Author : Constantino Carlos Reyes-Aldasoro,Andrew Janowczyk,Mitko Veta,Peter Bankhead,Korsuk Sirinukunwattana
Publisher : Springer
Release : 2019-07-03
ISBN : 3030239373
Language : En, Es, Fr & De

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Book Description :

This book constitutes the refereed proceedings of the 15th European Congress on Digital Pathology, ECDP 2019, held in Warwick, UK in April 2019. The 21 full papers presented in this volume were carefully reviewed and selected from 30 submissions. The congress theme will be Accelerating Clinical Deployment, with a focus on computational pathology and leveraging the power of big data and artificial intelligence to bridge the gaps between research, development, and clinical uptake.

Liquid Biopsy

Liquid Biopsy Book
Author : Ilze Strumfa,Janis Gardovskis
Publisher : BoD – Books on Demand
Release : 2019-07-10
ISBN : 183881129X
Language : En, Es, Fr & De

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Book Description :

Reliable diagnosis is the cornerstone, starting point, and prerequisite of successful treatment. Therefore, development of innovative diagnostic technologies represents a hot topic in medical research. Liquid biopsy is a novel, minimally invasive laboratory evaluation concept for diagnostic, prognostic, and predictive testing, as well as dynamic monitoring of treatment or disease course. To achieve these goals, a multitude of specific, targeted tests can be performed to detect free nucleic acids, exosomes, microRNAs, tumor-educated platelets, and whole cells of tumor or fetal origin in different biological fluids, including blood, urine, cerebrospinal fluid, and others. Although tissue biopsy has long been considered the gold standard of diagnostics, especially regarding malignant tumors, liquid biopsy has the advantages of a non-invasive approach and thus low risk of complications. It is technically feasible even in serious general status or if tumors or metastases are not easily accessible using conventional tissue biopsy. The testing is fast, exact, and can be repeated to ensure real-time follow-up. In contrast to classic tumor markers, liquid biopsy is distinguished by high specificity at genomic, proteomic, and cellular levels. It is expected to equal and exceed the diagnostic value of tissue biopsy. The field of liquid biopsies is developing rapidly regarding the selection of targets, technological improvements, and quality assessment. This book, written by a global team of recognized scientists, comprises state-of-the-art reviews on the current knowledge and advances in the technologies and software for liquid biopsy. Examples of practical application of liquid biopsy to evaluate thyroid cancer, multiple myeloma, etc. are discussed as well. The book is intended to serve as a reference for scientists and clinicians interested in the development and practical implementation of liquid biopsy.

Artificial Intelligence Applications In Human Pathology

Artificial Intelligence Applications In Human Pathology Book
Author : Ralf Huss,Michael Grunkin
Publisher : World Scientific
Release : 2022-03-04
ISBN : 1800611404
Language : En, Es, Fr & De

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Book Description :

Artificial Intelligence Applications in Human Pathology deals with the latest topics in biomedical research and clinical cancer diagnostics. With chapters provided by true international experts in the field, this book gives real examples of the implementation of AI and machine learning in human pathology.Advances in machine learning and AI in general have propelled computational and general pathology research. Today, computer systems approach the diagnostic levels achieved by humans for certain well-defined tasks in pathology. At the same time, pathologists are faced with an increased workload both quantitatively (numbers of cases) and qualitatively (the amount of work per case, with increasing treatment options and the type of data delivered by pathologists also expected to become more fine-grained). AI will support and leverage mathematical tools and implement data-driven methods as a center for data interpretation in modern tissue diagnosis and pathology. Digital or computational pathology will also foster the training of future computational pathologists, those with both pathology and non-pathology backgrounds, who will eventually decide that AI-based pathology will serve as an indispensable hub for data-related research in a global health care system.Some of the specific topics explored within include an introduction to DL as applied to Pathology, Standardized Tissue Sampling for Automated Analysis, integrating Computational Pathology into Histopathology workflows. Readers will also find examples of specific techniques applied to specific diseases that will aid their research and treatments including but not limited to; Tissue Cartography for Colorectal Cancer, Ki-67 Measurements in Breast Cancer, and Light-Sheet Microscopy as applied to Virtual Histology.The key role for pathologists in tissue diagnostics will prevail and even expand through interdisciplinary work and the intuitive use of an advanced and interoperating (AI-supported) pathology workflow delivering novel and complex features that will serve the understanding of individual diseases and of course the patient.

Histology for Pathologists

Histology for Pathologists Book
Author : Stacey E. Mills
Publisher : Lippincott Williams & Wilkins
Release : 2012-07-16
ISBN : 1451177801
Language : En, Es, Fr & De

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Book Description :

A strong grounding in basic histology is essential for all pathologists. However, there had always been a gap between histology and pathology in which histologic information specifically for the pathologist was often lacking. Histology for Pathologists deals with the microscopic features of normal human tissues, from the perspective of the surgical pathologist. This is the only text that uses human (vs. animal) tissues for the histology. It is the best reference in the literature for information on normal histology, and, as such, is essential for all clinical pathologists. Written by pathologists for pathologists, the new edition updates the pathologist's understanding of normal histology up to date with the incremental advances made in the last five years. The 3rd edition has become a "classic" purchased by virtually all residents beginning their pathology training, as well as pathologists in practice. The 4th edition builds on that substantial foundation. The table of contents remains essentially the same with the exception of some changes in authorship.

Natural Language Processing in Action

Natural Language Processing in Action Book
Author : Hannes Hapke,Cole Howard,Hobson Lane
Publisher : Simon and Schuster
Release : 2019-03-16
ISBN : 1638356890
Language : En, Es, Fr & De

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Book Description :

Summary Natural Language Processing in Action is your guide to creating machines that understand human language using the power of Python with its ecosystem of packages dedicated to NLP and AI. Purchase of the print book includes a free eBook in PDF, Kindle, and ePub formats from Manning Publications. About the Technology Recent advances in deep learning empower applications to understand text and speech with extreme accuracy. The result? Chatbots that can imitate real people, meaningful resume-to-job matches, superb predictive search, and automatically generated document summaries—all at a low cost. New techniques, along with accessible tools like Keras and TensorFlow, make professional-quality NLP easier than ever before. About the Book Natural Language Processing in Action is your guide to building machines that can read and interpret human language. In it, you'll use readily available Python packages to capture the meaning in text and react accordingly. The book expands traditional NLP approaches to include neural networks, modern deep learning algorithms, and generative techniques as you tackle real-world problems like extracting dates and names, composing text, and answering free-form questions. What's inside Some sentences in this book were written by NLP! Can you guess which ones? Working with Keras, TensorFlow, gensim, and scikit-learn Rule-based and data-based NLP Scalable pipelines About the Reader This book requires a basic understanding of deep learning and intermediate Python skills. About the Author Hobson Lane, Cole Howard, and Hannes Max Hapke are experienced NLP engineers who use these techniques in production. Table of Contents PART 1 - WORDY MACHINES Packets of thought (NLP overview) Build your vocabulary (word tokenization) Math with words (TF-IDF vectors) Finding meaning in word counts (semantic analysis) PART 2 - DEEPER LEARNING (NEURAL NETWORKS) Baby steps with neural networks (perceptrons and backpropagation) Reasoning with word vectors (Word2vec) Getting words in order with convolutional neural networks (CNNs) Loopy (recurrent) neural networks (RNNs) Improving retention with long short-term memory networks Sequence-to-sequence models and attention PART 3 - GETTING REAL (REAL-WORLD NLP CHALLENGES) Information extraction (named entity extraction and question answering) Getting chatty (dialog engines) Scaling up (optimization, parallelization, and batch processing)

Machine Learning in Medical Imaging

Machine Learning in Medical Imaging Book
Author : Chunfeng Lian,Xiaohuan Cao,Islem Rekik,Xuanang Xu,Pingkun Yan
Publisher : Springer Nature
Release : 2021-09-25
ISBN : 303087589X
Language : En, Es, Fr & De

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Book Description :

This book constitutes the proceedings of the 12th International Workshop on Machine Learning in Medical Imaging, MLMI 2021, held in conjunction with MICCAI 2021, in Strasbourg, France, in September 2021.* The 71 papers presented in this volume were carefully reviewed and selected from 92 submissions. They focus on major trends and challenges in the above-mentioned area, aiming to identify new-cutting-edge techniques and their uses in medical imaging. Topics dealt with are: deep learning, generative adversarial learning, ensemble learning, sparse learning, multi-task learning, multi-view learning, manifold learning, and reinforcement learning, with their applications to medical image analysis, computer-aided detection and diagnosis, multi-modality fusion, image reconstruction, image retrieval, cellular image analysis, molecular imaging, digital pathology, etc. *The workshop was held virtually.

Artificial Intelligence in Medicine

Artificial Intelligence in Medicine Book
Author : Lei Xing,Maryellen L. Giger,James K. Min
Publisher : Academic Press
Release : 2020-09-03
ISBN : 0128212586
Language : En, Es, Fr & De

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Book Description :

Artificial Intelligence Medicine: Technical Basis and Clinical Applications presents a comprehensive overview of the field, ranging from its history and technical foundations, to specific clinical applications and finally to prospects. Artificial Intelligence (AI) is expanding across all domains at a breakneck speed. Medicine, with the availability of large multidimensional datasets, lends itself to strong potential advancement with the appropriate harnessing of AI. The integration of AI can occur throughout the continuum of medicine: from basic laboratory discovery to clinical application and healthcare delivery. Integrating AI within medicine has been met with both excitement and scepticism. By understanding how AI works, and developing an appreciation for both limitations and strengths, clinicians can harness its computational power to streamline workflow and improve patient care. It also provides the opportunity to improve upon research methodologies beyond what is currently available using traditional statistical approaches. On the other hand, computers scientists and data analysts can provide solutions, but often lack easy access to clinical insight that may help focus their efforts. This book provides vital background knowledge to help bring these two groups together, and to engage in more streamlined dialogue to yield productive collaborative solutions in the field of medicine. Provides history and overview of artificial intelligence, as narrated by pioneers in the field Discusses broad and deep background and updates on recent advances in both medicine and artificial intelligence that enabled the application of artificial intelligence Addresses the ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach

Deep Learning for Cancer Diagnosis

Deep Learning for Cancer Diagnosis Book
Author : Utku Kose,Jafar Alzubi
Publisher : Springer Nature
Release : 2020-09-12
ISBN : 9811563217
Language : En, Es, Fr & De

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Book Description :

This book explores various applications of deep learning to the diagnosis of cancer,while also outlining the future face of deep learning-assisted cancer diagnostics. As is commonly known, artificial intelligence has paved the way for countless new solutions in the field of medicine. In this context, deep learning is a recent and remarkable sub-field, which can effectively cope with huge amounts of data and deliver more accurate results. As a vital research area, medical diagnosis is among those in which deep learning-oriented solutions are often employed. Accordingly, the objective of this book is to highlight recent advanced applications of deep learning for diagnosing different types of cancer. The target audience includes scientists, experts, MSc and PhD students, postdocs, and anyone interested in the subjects discussed. The book can be used as a reference work to support courses on artificial intelligence, medical and biomedicaleducation.

Deep Learning in Healthcare

Deep Learning in Healthcare Book
Author : Yen-Wei Chen,Lakhmi C. Jain
Publisher : Springer Nature
Release : 2019-11-18
ISBN : 3030326063
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of deep learning (DL) in medical and healthcare applications, including the fundamentals and current advances in medical image analysis, state-of-the-art DL methods for medical image analysis and real-world, deep learning-based clinical computer-aided diagnosis systems. Deep learning (DL) is one of the key techniques of artificial intelligence (AI) and today plays an important role in numerous academic and industrial areas. DL involves using a neural network with many layers (deep structure) between input and output, and its main advantage of is that it can automatically learn data-driven, highly representative and hierarchical features and perform feature extraction and classification on one network. DL can be used to model or simulate an intelligent system or process using annotated training data. Recently, DL has become widely used in medical applications, such as anatomic modelling, tumour detection, disease classification, computer-aided diagnosis and surgical planning. This book is intended for computer science and engineering students and researchers, medical professionals and anyone interested using DL techniques.

Deep Learning for Coders with fastai and PyTorch

Deep Learning for Coders with fastai and PyTorch Book
Author : Jeremy Howard,Sylvain Gugger
Publisher : "O'Reilly Media, Inc."
Release : 2020-06-29
ISBN : 1492045470
Language : En, Es, Fr & De

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Book Description :

Deep learning is often viewed as the exclusive domain of math PhDs and big tech companies. But as this hands-on guide demonstrates, programmers comfortable with Python can achieve impressive results in deep learning with little math background, small amounts of data, and minimal code. How? With fastai, the first library to provide a consistent interface to the most frequently used deep learning applications. Authors Jeremy Howard and Sylvain Gugger, the creators of fastai, show you how to train a model on a wide range of tasks using fastai and PyTorch. You’ll also dive progressively further into deep learning theory to gain a complete understanding of the algorithms behind the scenes. Train models in computer vision, natural language processing, tabular data, and collaborative filtering Learn the latest deep learning techniques that matter most in practice Improve accuracy, speed, and reliability by understanding how deep learning models work Discover how to turn your models into web applications Implement deep learning algorithms from scratch Consider the ethical implications of your work Gain insight from the foreword by PyTorch cofounder, Soumith Chintala

Machine Learning in Cardiovascular Medicine

Machine Learning in Cardiovascular Medicine Book
Author : Subhi J. Al'Aref,Gurpreet Singh,Lohendran Baskaran,Dimitri Metaxas
Publisher : Academic Press
Release : 2020-11-20
ISBN : 0128202742
Language : En, Es, Fr & De

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Book Description :

Machine Learning in Cardiovascular Medicine addresses the ever-expanding applications of artificial intelligence (AI), specifically machine learning (ML), in healthcare and within cardiovascular medicine. The book focuses on emphasizing ML for biomedical applications and provides a comprehensive summary of the past and present of AI, basics of ML, and clinical applications of ML within cardiovascular medicine for predictive analytics and precision medicine. It helps readers understand how ML works along with its limitations and strengths, such that they can could harness its computational power to streamline workflow and improve patient care. It is suitable for both clinicians and engineers; providing a template for clinicians to understand areas of application of machine learning within cardiovascular research; and assist computer scientists and engineers in evaluating current and future impact of machine learning on cardiovascular medicine. Provides an overview of machine learning, both for a clinical and engineering audience Summarize recent advances in both cardiovascular medicine and artificial intelligence Discusses the advantages of using machine learning for outcomes research and image processing Addresses the ever-expanding application of this novel technology and discusses some of the unique challenges associated with such an approach

Artificial Intelligence in Healthcare

Artificial Intelligence in Healthcare Book
Author : Adam Bohr,Kaveh Memarzadeh
Publisher : Academic Press
Release : 2020-06-21
ISBN : 0128184396
Language : En, Es, Fr & De

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Book Description :

Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Artificial Intelligence in Medical Imaging

Artificial Intelligence in Medical Imaging Book
Author : Lia Morra,Silvia Delsanto,Loredana Correale
Publisher : CRC Press
Release : 2019-11-25
ISBN : 1000753085
Language : En, Es, Fr & De

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Book Description :

This book, written by authors with more than a decade of experience in the design and development of artificial intelligence (AI) systems in medical imaging, will guide readers in the understanding of one of the most exciting fields today. After an introductory description of classical machine learning techniques, the fundamentals of deep learning are explained in a simple yet comprehensive manner. The book then proceeds with a historical perspective of how medical AI developed in time, detailing which applications triumphed and which failed, from the era of computer aided detection systems on to the current cutting-edge applications in deep learning today, which are starting to exhibit on-par performance with clinical experts. In the last section, the book offers a view on the complexity of the validation of artificial intelligence applications for commercial use, describing the recently introduced concept of software as a medical device, as well as good practices and relevant considerations for training and testing machine learning systems for medical use. Open problematics on the validation for public use of systems which by nature continuously evolve through new data is also explored. The book will be of interest to graduate students in medical physics, biomedical engineering and computer science, in addition to researchers and medical professionals operating in the medical imaging domain, who wish to better understand these technologies and the future of the field. Features: An accessible yet detailed overview of the field Explores a hot and growing topic Provides an interdisciplinary perspective