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Applications In High Resolution Mass Spectrometry

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Applications in High Resolution Mass Spectrometry

Applications in High Resolution Mass Spectrometry Book
Author : Roberto Romero-González,Antonia Garrido Frenich
Publisher : Elsevier
Release : 2017-03-07
ISBN : 0128096489
Language : En, Es, Fr & De

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Book Description :

Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis Features a chapter on the hardware and software available for HRMS implementation Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

High Resolution Mass Spectroscopy for Phytochemical Analysis

High Resolution Mass Spectroscopy for Phytochemical Analysis Book
Author : Sreeraj Gopi,Augustine Amalraj,Shintu Jude
Publisher : CRC Press
Release : 2021-09-30
ISBN : 1000353419
Language : En, Es, Fr & De

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Book Description :

This new volume provides a bird’s-eye view of the properties, utilization, and importance of high resolution mass spectrometry (HRMS) for phytochemical analysis. The book discusses the new and state-of-the-art technologies related to HRMS in phytochemical analysis for the food industry in a comprehensive manner. Phytochemical characterization of plants is important in the food and nutraceutical industries and is also necessary in the procedures followed for drug development, toxicology determination, forensic studies, origin verification, quality assurance, etc. Easy determination of active compounds and isolation as well as purification of the same from natural matrices are required, and the possibilities and advantages of HRMS pave the way for improved analysis patterns in phytochemistry. This book is unique in that its sole consideration is on the importance of HRMS in the field of phytochemical analysis. Along with an overview of basic instrumental information, the volume provides a detailed account of data processing and dereplication strategies. Technologies such as bioanalytical techniques and bioassays are considered also to provide support for the functions of the instruments used. In addition, a case study is presented to depict the complete phytochemical characterization of a matrix by HRMS. The book covers processing and computational techniques, dereplication, hyphenation, high-resolution bioassays, bioanalytical screening/purification techniques, applications of gas chromatography–high-resolution mass spectrometry, and more. Key features: Covers the fundamental instrumentation and techniques Discusses HRMS-based phytochemical research details Focuses strictly on the phytochemical considerations High-Resolution Mass Spectroscopy for Phytochemical Analysis: State-of-the-Art Applications and Techniques will be a valuable reference guide and resource for researchers, faculty and students in related fields, as well as those in the phytochemical industries.

High Resolution Mass Spectrometry and Its Diverse Applications

High Resolution Mass Spectrometry and Its Diverse Applications Book
Author : Sreeraj Gopi,Sabu Thomas,Augustine Amalraj,Shintu Jude
Publisher : CRC Press
Release : 2022-12-22
ISBN : 1000612880
Language : En, Es, Fr & De

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Book Description :

This informative book offers a wide range of knowledge on the technologies and applications of the cutting-edge field of high-resolution mass spectrometry (HRMS) in different areas of analysis. HRMS has changed the nature of experimentation and investigation in so many analytical realms. Determining exact mass determination, high resolution, and specificity—via the special features provided by HRMS instruments—is now possible for determining the composition of the analyte of interest, both qualitatively and quantitatively. High-Resolution Mass Spectrometry and Its Diverse Applications: Cutting-Edge Techniques and Instrumentation begins with an overview of the basic instrumentation techniques and goes on to present research on diverse new uses of HRMS in clinical testing, such as for therapeutic drug designing, discovery, and development; in forensic studies and investigations; in quality management systems; for analysis of pesticides; for analysis of single cells; in analysis of fossil fuels; for use in space and planetary science; and more. Chapters relay how HRMS plays an important role in the structure elucidation and unknown determination in many fields and is a great measure to be used for quantitative analyses. The book considers how these properties make the technique a strong aid in many areas. This volume highlights how HRMS can be a useful tool for scientists and researchers, faculty and students, and industry professionals in many scientific areas of study.

Current Practice of Gas Chromatography Mass Spectrometry

Current Practice of Gas Chromatography Mass Spectrometry Book
Author : Wilfried M.A. Niessen
Publisher : CRC Press
Release : 2001-04-04
ISBN : 9781420029512
Language : En, Es, Fr & De

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Book Description :

This volume details the principles and instrumentation of gas chromatography-mass spectrometry (CG-MS), and outlines industrial, environmental, pharmaceutical, clinical, toxicological, forensic and food-related applications, revealing findings from the laboratories of 40 contributing scientists around the world using GC-MS in practice. It describes upstream and downstream applications of GC-MS in the petroleum industry and identifies chlorinated compounds in the environment with quadrupole ion-trap technology and high-resolution sector instruments.

Applications in High Resolution Mass Spectrometry

Applications in High Resolution Mass Spectrometry Book
Author : Roberto Romero-González,Antonia Garrido Frenich
Publisher : Elsevier
Release : 2017-06-01
ISBN : 9780128094648
Language : En, Es, Fr & De

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Book Description :

Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis Features a chapter on the hardware and software available for HRMS implementation Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

Determination of Target Xenobiotics and Unknown Compound Residues in Food Environmental and Biological Samples

Determination of Target Xenobiotics and Unknown Compound Residues in Food  Environmental  and Biological Samples Book
Author : Tomasz Tuzimski,Joseph Sherma
Publisher : CRC Press
Release : 2018-10-25
ISBN : 042982310X
Language : En, Es, Fr & De

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Book Description :

Xenobiotics are chemical compounds foreign to a given biological system. In animals and humans, xenobiotics include drugs, drug metabolites, and environmental pollutants. In the environment, xenobiotics include synthetic pesticides, herbicides, and industrial pollutants. Many techniques are used in xenobiotics residue analysis; the method selected depends on the complexity of the sample, the nature of the matrix/analytes, and the analytical techniques available. This reference will help the analyst develop effective and validated analytical strategies for the analysis of hundreds of different xenobiotics on hundreds of different sample types, quickly, accurately and at acceptable cost.

Liquid Chromatography Time of Flight Mass Spectrometry

Liquid Chromatography Time of Flight Mass Spectrometry Book
Author : Imma Ferrer,E. Michael Thurman
Publisher : John Wiley & Sons
Release : 2009-05-06
ISBN : 9780470429952
Language : En, Es, Fr & De

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Book Description :

Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists, university research chemists, and graduate and post-doctorate students.

Protein Analysis using Mass Spectrometry

Protein Analysis using Mass Spectrometry Book
Author : Mike S. Lee,Qin C. Ji
Publisher : John Wiley & Sons
Release : 2017-05-26
ISBN : 1119359368
Language : En, Es, Fr & De

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Book Description :

Presents Practical Applications of Mass Spectrometry for Protein Analysis and Covers Their Impact on Accelerating Drug Discovery and Development Covers both qualitative and quantitative aspects of Mass Spectrometry protein analysis in drug discovery Principles, Instrumentation, Technologies topics include MS of peptides, proteins, and ADCs , instrumentation in protein analysis, nanospray technology in MS protein analysis, and automation in MS protein analysis Details emerging areas from drug monitoring to patient care such as Identification and validation of biomarkers for cancer, targeted MS approaches for biomarker validation, biomarker discovery, and regulatory perspectives Brings together the most current advances in the mass spectrometry technology and related method in protein analysis

Bibliography of Mass Spectroscopy Literature for 1970

Bibliography of Mass Spectroscopy Literature for 1970 Book
Author : Anonim
Publisher : Unknown
Release : 1972
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Bibliography of Mass Spectroscopy Literature for 1970 book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Time of Flight Mass Spectrometry and its Applications

Time of Flight Mass Spectrometry and its Applications Book
Author : E.W. Schlag
Publisher : Newnes
Release : 2012-12-02
ISBN : 0444596186
Language : En, Es, Fr & De

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Book Description :

The resurgence of time-of-flight mass spectrometry (TOF-MS) has had its origin in the simplicity of construction and application of such instruments together with the high transmission and the great increase in resolution that has been achieved. The instrument lends itself naturally to a coupling with pulsed laser sources, though this is not a prerequisite. It also affords a time resolution far beyond that traditionally achieved with mass spectrometric rapid scan techniques - a recent example being the real-time analysis of a multi-component mixture from an automobile exhaust. Furthermore, the mass range appears to be extremely large: mass up to 500 kDa and beyond what is being readily measured in the laboratory today. The present set of contributions attempts to give a survey of current applications from many of the active groups in the field. A variety of new applications are considered which are no doubt just the beginning of large new areas of application. By presenting this work in book form it is hoped that it will be of help to the many groups intending to initiate work in this rapidly expanding new area of mass spectrometry.

Methods for Novel Psychoactive Substance Analysis

Methods for Novel Psychoactive Substance Analysis Book
Author : Marta Concheiro,Karl B. Scheidweiler
Publisher : Springer Nature
Release : 2022-11-13
ISBN : 1071626051
Language : En, Es, Fr & De

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Book Description :

This collection provides detailed information on current advances in analytical methods and strategies employed for monitoring and discovering a wide range of novel psychoactive substances (NPS) in clinical and forensic laboratories. The main classes of NPS in terms of prevalence include synthetic cannabinoids, synthetic cathinones, synthetic opioids, and designer or synthetic benzodiazepines, and this book explores selecting the appropriate sample matrix and analytical testing approaches for laboratories faced with NPS drug testing, such as in blood, urine, saliva, and hair. Written for the Methods in Pharmacology and Toxicology series, chapters in this volume feature the kind of detailed implementation advice from the experts that leads to successful results in the lab. Authoritative and practical, Methods for Novel Psychoactive Substance Analysis serves as an ideal guide for forensic and clinical toxicologists, pharmacologists and chemists in academic and research settings, as well as for private laboratories seeking to increase our ability to test for these substances. @font-face {font-family:"Cambria Math"; panose-1:2 4 5 3 5 4 6 3 2 4; mso-font-charset:0; mso-generic-font-family:roman; mso-font-pitch:variable; mso-font-signature:-536869121 1107305727 33554432 0 415 0;}@font-face {font-family:Calibri; panose-1:2 15 5 2 2 2 4 3 2 4; mso-font-charset:0; mso-generic-font-family:swiss; mso-font-pitch:variable; mso-font-signature:-469750017 -1073732485 9 0 511 0;}p.MsoNormal, li.MsoNormal, div.MsoNormal {mso-style-unhide:no; mso-style-qformat:yes; mso-style-parent:""; margin:0cm; mso-pagination:widow-orphan; font-size:12.0pt; mso-bidi-font-size:11.0pt; font-family:"Times New Roman",serif; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}.MsoChpDefault {mso-style-type:export-only; mso-default-props:yes; mso-bidi-font-size:11.0pt; mso-fareast-font-family:Calibri; mso-fareast-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi; mso-ansi-language:EN-US; mso-fareast-language:EN-US;}div.WordSection1 {page:WordSection1;}

Encyclopedia of Geochemistry

Encyclopedia of Geochemistry Book
Author : William M. White
Publisher : Springer
Release : 2018-07-24
ISBN : 9783319393117
Language : En, Es, Fr & De

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Book Description :

The Encyclopedia is a complete and authoritative reference work for this rapidly evolving field. Over 200 international scientists, each experts in their specialties, have written over 330 separate topics on different aspects of geochemistry including geochemical thermodynamics and kinetics, isotope and organic geochemistry, meteorites and cosmochemistry, the carbon cycle and climate, trace elements, geochemistry of high and low temperature processes, and ore deposition, to name just a few. The geochemical behavior of the elements is described as is the state of the art in analytical geochemistry. Each topic incorporates cross-referencing to related articles, and also has its own reference list to lead the reader to the essential articles within the published literature. The entries are arranged alphabetically, for easy access, and the subject and citation indices are comprehensive and extensive. Geochemistry applies chemical techniques and approaches to understanding the Earth and how it works. It touches upon almost every aspect of earth science, ranging from applied topics such as the search for energy and mineral resources, environmental pollution, and climate change to more basic questions such as the Earth’s origin and composition, the origin and evolution of life, rock weathering and metamorphism, and the pattern of ocean and mantle circulation. Geochemistry allows us to assign absolute ages to events in Earth’s history, to trace the flow of ocean water both now and in the past, trace sediments into subduction zones and arc volcanoes, and trace petroleum to its source rock and ultimately the environment in which it formed. The earliest of evidence of life is chemical and isotopic traces, not fossils, preserved in rocks. Geochemistry has allowed us to unravel the history of the ice ages and thereby deduce their cause. Geochemistry allows us to determine the swings in Earth’s surface temperatures during the ice ages, determine the temperatures and pressures at which rocks have been metamorphosed, and the rates at which ancient magma chambers cooled and crystallized. The field has grown rapidly more sophisticated, in both analytical techniques that can determine elemental concentrations or isotope ratios with exquisite precision and in computational modeling on scales ranging from atomic to planetary.

Applications of Time of Flight and Orbitrap Mass Spectrometry in Environmental Food Doping and Forensic Analysis

Applications of Time of Flight and Orbitrap Mass Spectrometry in Environmental  Food  Doping  and Forensic Analysis Book
Author : Anonim
Publisher : Elsevier
Release : 2016-06-02
ISBN : 0444635734
Language : En, Es, Fr & De

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Book Description :

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance. This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS. Provides comprehensive coverage of applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis Explores a variety of specialized techniques, giving a balanced description of the strengths and weaknesses of each Presents a general overview of imaging techniques within analysis

Fundamentals and Applications of Fourier Transform Mass Spectrometry

Fundamentals and Applications of Fourier Transform Mass Spectrometry Book
Author : Philippe Schmitt-Kopplin,Basem Kanawati
Publisher : Elsevier
Release : 2019-08-11
ISBN : 0128140143
Language : En, Es, Fr & De

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Book Description :

Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. Covers FT-ICR-MS and Orbitrap’s fundamentals, enhancing researcher knowledge Includes details on ion sources, data processing, chemical analysis and imaging Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

Applications of Gas Chromatography

Applications of Gas Chromatography Book
Author : Adrianna Coty
Publisher : Unknown
Release : 2016-04-01
ISBN : 9781681172620
Language : En, Es, Fr & De

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Book Description :

Gas chromatography is a term used to describe the group of analytical separation techniques used to analyze volatile substances in the gas phase. In gas chromatography, the components of a sample are dissolved in a solvent and vaporized in order to separate the analyses by distributing the sample between two phases: a stationary phase and a mobile phase. The mobile phase is a chemically inert gas that serves to carry the molecules of the analyze through the heated column. Gas chromatography is one of the sole forms of chromatography that does not utilize the mobile phase for interacting with the analyze. The stationary phase is either a solid adsorbent, termed gas-solid chromatography (GSC), or a liquid on an inert support, termed gas-liquid chromatography (GLC). Helium remains the most commonly used carrier gas in about 90% of instruments although hydrogen is preferred for improved separations. This inert gas goes through a glass column packed with silica that is coated with a liquid. Materials that are less soluble in the liquid will increase the result faster than the material with greater solubility. The purpose of this book entitled Applications of Gas Chromatography is to provide a better understanding on its separation and measurement techniques and its application. Since chromatography techniques are separating and analyzing methods, this book will help other researchers and young scientists to choose a suitable chromatography technique. Furthermore, this book illustrates the newest challenges in this area. This valuable book aims to provide a connection between various chromatography techniques and different processes.

Applications of Modern Mass Spectrometry Volume 1

Applications of Modern Mass Spectrometry  Volume 1 Book
Author : Atta-ur-Rahman, M. Iqbal Choudhary,Syed Ghulam Musharraf
Publisher : Bentham Science Publishers
Release : 2020-07-02
ISBN : 9811433801
Language : En, Es, Fr & De

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Book Description :

Applications of Modern Mass Spectrometry covers the latest advances in the use of mass spectrometry in scientific research. The series attempts to present readers information on the broad range of mass spectrometry techniques and configurations, data analysis and practical applications. Each volume contains contributions from eminent researchers who present their findings in an easy to read format. The multidisciplinary nature of the works presented in each volume of this book series make it a valuable reference on mass spectrometry to academic researchers and industrial R&D specialists in applied sciences, biochemistry, life sciences and allied fields. The first volume of the series presents 5 reviews: - Applications of mass spectrometry for the determination of the microbial crude protein synthesis in ruminants - Qualitative and quantitative LC-MS analysis in food proteins and peptides - Chemometrics as a powerful and complementary tool for mass spectrometry applications in life sciences - Recent developments of allied techniques of qualitative analysis of heavy metal ions in aqueous solutions with special reference to modern mass spectrometry - New techniques and methods in explosive analysis.

Mass Spectrometry of Organic Ions

Mass Spectrometry of Organic Ions Book
Author : F.W. McLafferty
Publisher : Elsevier
Release : 2012-12-02
ISBN : 032314277X
Language : En, Es, Fr & De

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Book Description :

Mass Spectrometry of Organic Ions covers the underlying theories and major applications of mass spectrometry. This 13-chapter book starts with a survey of the mechanisms by which organic ions can decompose and rearrange, as well as the generalized concept in terms of physical-organic chemistry. The discussion then shifts to the advantages and potential of mass spectrometry in structure determination by the elucidation of the empirical formulas of organic ions. Considerable chapters are devoted to the detailed correlations and mechanisms of the mass spectra of long-chain esters, alkylbenzenes, a variety of natural products, aliphatic compounds, and terpenes. The remaining chapters demonstrate the illustrative power of mass spectrometry in structure of petroleum, which is composed of hydrocarbon mixture. This book will be of great benefit to organic and analytical chemists, scientists, and students.

Mass Spectrometry

Mass Spectrometry Book
Author : Jürgen H Gross
Publisher : Springer Science & Business Media
Release : 2006-04-05
ISBN : 3540407391
Language : En, Es, Fr & De

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Book Description :

Mass Spectrometry is an ideal textbook for students and professionals as well as newcomers to the field. Starting from the very first principles of gas-phase ion chemistry and isotopic properties, the textbook takes the reader through the design of mass analyzers and ionization methods all the way to mass spectral interpretation and coupling techniques. Step-by-step, the reader learns how mass spectrometry works and what it can do. The book comprises a balanced mixture of practice-oriented information and theoretical background. It features a clear layout and a wealth of high-quality figures. Exercises and solutions are located on the Springer Global Web.

Metabolic Profiling

Metabolic Profiling Book
Author : Georgios A. Theodoridis,Helen G. Gika,Ian D. Wilson
Publisher : Humana
Release : 2019-04-30
ISBN : 9781493992522
Language : En, Es, Fr & De

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Book Description :

This volume explores the different approaches and techniques used by researchers to study the recent challenges and developments in metabolic profiling. This book is divided into IV parts. Part I contains chapters that highlight basic concepts, such as experimental design, data treatment, metabolite identification, and harmonization. Part II describes experimental protocols for both targeted and untargeted metabolomics covering the basic analytical technologies: LC-MS, GC-MS, NMR and CE-MS. In addition the protocols describe methods for the study of tissues, feces, blood and other types of biological samples as well as the application of chemical derivatization for GC-MS. Parts III and IV present the use of metabolomics in the study of food, plants and the life sciences, with examples from the quest for the discovery of disease biomarkers, physical exercise omics and metabolic profiling of food, fruit and wine. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Metabolic Profiling: Methods and Protocols is a valuable resource for researchers who are interested in expanding their knowledge of this rapidly developing field.

Clinical Applications of Mass Spectrometry in Biomolecular Analysis

Clinical Applications of Mass Spectrometry in Biomolecular Analysis Book
Author : Uttam Garg
Publisher : Humana Press
Release : 2015-11-25
ISBN : 9781493931811
Language : En, Es, Fr & De

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Book Description :

This volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and no need for specialized reagents. The techniques described are a must for the measurement of many clinically relevant analytes in the fields of drug analysis, endocrinology, and inborn errors of metabolism. Each chapter provides a brief introduction about a specified analyte, followed by detailed instructions on the analytical protocol. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols is a great resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.