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Antiphospholipid Syndrome In Systemic Autoimmune Diseases

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Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Antiphospholipid Syndrome in Systemic Autoimmune Diseases Book
Author : Ricard Cervera,Gerard Espinosa,Munther Khamashta
Publisher : Elsevier
Release : 2016-06-18
ISBN : 0444636560
Language : En, Es, Fr & De

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Book Description :

Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease. Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics. Brings the reader up-to-date and allows easy access to individual topics in one place Written by a respected panel of distinguished physicians/scientists actively involved in the field of Antiphospholipid Syndrome Includes box summaries at the end of each chapter that highlight important topics Gives up-to-date, basic knowledge and a modern approach to diagnosis and therapy Provides a comprehensive review of this major disease Includes information on treatment options available

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases Book
Author : Michael Lockshin,D. Ware Branch
Publisher : Gulf Professional Publishing
Release : 2006
ISBN : 0444518010
Language : En, Es, Fr & De

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Book Description :

This volume of the Handbook of Systemic Autoimmune Diseases series represents a medical collaboration focusing primarily on female aspects of rheumatic diseases. This collaboration recognizes the need to understand and optimally manage the care of women with autoimmune conditions that may affect their reproduction and hormonal status. This handbook will prove useful to clinicians and researchers alike. It covers practical points, ranging from which anti-rheumatic medications are safe in pregnancy to how to counsel women with scleroderma contemplating pregnancy. * Authors share an academic interest in the unique relationship between being a woman and having an autoimmune disease * Touches on controversial topics, such as the mechanism of antiphospholipid-related fetal loss and whether or not non-steroidal anti-inflammatory agents should be used in pregnancy * Includes critical and balanced reviews of the controversial association between autoimmune disease and female infertility

The Skin in Systemic Autoimmune Diseases

The Skin in Systemic Autoimmune Diseases Book
Author : Piercarlo Sarzi-Puttini
Publisher : Elsevier
Release : 2006-01-26
ISBN : 9780080461922
Language : En, Es, Fr & De

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Book Description :

This book represents the state-of-the-art in the field of skin and autoimmune rheumatic diseases. It covers systematically a growing and multifaceted topic which is of great importance in the clinical practice. It also serves as a sharp educational tool as each chapter provides summaries and specific highlights to key references cited into the text. The pathophysiological link between skin involvement and autoimmunity has been explained in detail, as well as diagnostic and therapeutic aspects. This book yields an impressive body of well ordered information which summarizes the experience of a selected panel of distinguished physicians and scientists actively involved in the field of skin immunology and systemic autoimmunity. * Written by a respected panel of distinguished physician-scientists actively involved in the field of skin immunology and systemic autoimmunity * Box summaries at the end of each chapter highlight important topics * Up-to-date basic knowledge as well as modern approach to diagnosis and therapy

Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Antiphospholipid Syndrome in Systemic Autoimmune Diseases Book
Author : R. Cervera,Ricard Cervera
Publisher : Elsevier
Release : 2009-04-01
ISBN : 9780080932347
Language : En, Es, Fr & De

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Book Description :

Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy and memory loss and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, from psychiatry to orthopedics. This book provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved as well as clinical manifestations in both “the thrombotic and “non-thrombotic manifestations of this important disease. * Comprehensive review of this major disease * Includes information on treatment options available

Systemic Lupus Erythematosus and Antiphospholipid Syndrome

Systemic Lupus Erythematosus and Antiphospholipid Syndrome Book
Author : Pier Luigi Meroni,George C. Tsokos
Publisher : Frontiers Media SA
Release : 2019-08-12
ISBN : 2889459799
Language : En, Es, Fr & De

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Book Description :

Download Systemic Lupus Erythematosus and Antiphospholipid Syndrome book written by Pier Luigi Meroni,George C. Tsokos, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Autoimmune Diseases

Autoimmune Diseases Book
Author : Munther A Khamashta,Manuel Ramos-Casals
Publisher : Springer
Release : 2011-05-27
ISBN : 9780857293572
Language : En, Es, Fr & De

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Book Description :

Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

Antiphospholipid Syndrome

Antiphospholipid Syndrome Book
Author : Doruk Erkan,Michael D. Lockshin
Publisher : Springer
Release : 2017-06-09
ISBN : 3319554425
Language : En, Es, Fr & De

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Book Description :

This new edition is a comprehensive and updated resource on antiphospholipid syndrome (APS), which is an autoimmune disorder. In APS, the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies (antiphospholipid antibodies) against them. APS is associated with recurrent clotting events (thrombosis) including premature stroke, repeated miscarriages, phlebitis, venous thrombosis, and pulmonary thromboembolism. It is also associated with low platelet or blood elements that prevent bleeding. Recently, however, even more disease states have been linked with APS, including premature heart attack, various cardiac valvular abnormalities, skin lesions, kidney disease, abnormal involuntary movement/chorea, diseases that mimic multiple sclerosis, and vascular diseases of the eye that can lead to visual loss and blindness. The International Congress on Antiphospholipid Antibodies, held every 3 years, is the venue where representatives from different disciplines gather to discuss the recent advances in APS. The conference intends to cover basic aspects of APS, such as pathogenesis, origins, genetics, intracellular and molecular events, the role of infections, as well as traditional and non-traditional clinical manifestations associated with antiphospholipid antibodies. The 15th Congress took place in September 2016. A novel aspect of the Congress was that multiple teams, chaired by Scientific Planning Committee members, used evidence-based literature reviews and expert discussions to answer specific pre-defined APS-related questions. These teams included points of view from experts in rheumatology, hematology, cardiovascular medicine, obstetrics, neurology, and immunology. The Scientific Planning Committee members also chaired the congress sessions and supervised completion of the reports that are the bases of the chapters of this book. In addition, there are two chapters included specifically written for APS patients. Much like the previous volume, dedicated to the 13th International Congress on Antiphospholipid Antibodies (April 2010), this up-to-date and comprehensive work gathers invaluable insights from a multidisciplinary team of world-renowned experts and represents the authoritative resource on causes, symptoms, diagnosis, and treatment of APS.​​

Antiphospholipid Antibody Syndrome

Antiphospholipid Antibody Syndrome Book
Author : Pier Luigi Meroni
Publisher : Springer
Release : 2014-11-20
ISBN : 3319110446
Language : En, Es, Fr & De

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Book Description :

This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

Connective Tissue Disease

Connective Tissue Disease Book
Author : Dario Roccatello,Lorenzo Emmi
Publisher : Springer
Release : 2016-04-09
ISBN : 331924535X
Language : En, Es, Fr & De

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Book Description :

In this volume devoted to systemic lupus erythematosus (SLE) and Sjögren syndrome, leading specialists from different disciplines present the latest research findings on many aspects of the diseases and describe the most recent trends in treatment, such as the “treat to target” approach. Both basic science and clinical medicine are addressed, with emphasis on the most promising clinical and laboratory-based studies. The coverage is comprehensive in scope, encompassing, for example, epidemiology, pathogenesis, autoantibodies and biomarkers, disease manifestations, involvement of different organs or systems, relationships with other disorders, biological therapy of SLE, and systemic treatment of Sjögren syndrome. Readers will find this first volume of Connective Tissue Disease to be an excellent source of information on the current understanding of, and clinical approach to, SLE and Sjögren syndrome that clearly conveys the progress made in recent years.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus Book
Author : Hani Almoallim
Publisher : BoD – Books on Demand
Release : 2012-03-21
ISBN : 9535102664
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive overview of the basic and clinical sciences of Systemic Lupus Erythematosus. It is suitable for basic scientists looking for detailed coverage of their areas of interest. It describes how advances in molecular biology have increased our understanding of this disease. It is a valuable clinical resource for practicing clinicians from different disciplines including rheumatologists, rheumatology fellows and residents. This book provides convenient access to information you need about cytokines, genetics, Fas pathway, toll like receptors and atherogenesis in SLE. Animal models have been reviewed as well. How to avoid delay in SLE diagnosis and management, in addition to various clinical manifestations including pregnancy and SLE have all been explained thoroughly in this book.

The Heart in Systemic Autoimmune Diseases

The Heart in Systemic Autoimmune Diseases Book
Author : Andrea Dorea
Publisher : Elsevier
Release : 2004-01-20
ISBN : 0080507964
Language : En, Es, Fr & De

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Book Description :

This first volume represents the state-of-the-art in the field of cardiovascular disease and autoimmune rheumatic diseases. Systemic autoimmune diseases comprise a family of conditions that share common pathogenetic mechanisms as well as a multi-organ involvement including the heart. This volume has been subdivided into three parts. In the first part, the immune mechanisms involved in cardiac damage have been considered. The role of proinflammatory and regulatory cytokines in driving an autoimmune response to cardiac self-tissues has been analysed. Moreover, the prevalence, the clinical meaning and the hypothetical pathogenicity of a broad spectrum of organ and non-organ specific autoantibodies have been discussed in detail. In the second part of the volume, the role of humoral and innate immunity in promoting the development of atherosclerotic plaque has been extensively reviewed, along with the newly discovered anti-inflammatory properties of statins. These two parts of the volume deal with exciting aspects of this topic, suggesting a very close connection between heart diseases and immunology. Finally, in the third part, the cardiac manifestations observed in the major systemic autoimmune conditions have been comprehensively examined. This book yields an impressive body of well ordered information, highlighting key references and summarising the experience of a selected panel of distinguished physician-scientists actively involved in the field of cardiovascular disease and systemic autoimmunity.

The Antiphospholipid Syndrome

The Antiphospholipid Syndrome Book
Author : Ronald A. Asherson
Publisher : CRC Press
Release : 2018-05-04
ISBN : 1351094025
Language : En, Es, Fr & De

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Book Description :

Written by the foremost researchers in the field, this book gathers together in a single source the many important clinical associations of antiphospholipid antibodies. Antibody-related clotting mechanisms and their relationship to conditions such as recurrent strokes, chorea, multi infarct dementias, a variety of spinal syndromes, Addison's Disease, recurrent miscarriages, and many more are discussed in depth. The importance of these antibodies in 'Primary,' 'Secondary,' and 'Catastrophic' Antiphospholipid Syndrome is highlighted. Each chapter is devoted to a specific internal system and the clinical effects this syndrome has on that system. This authoritative book is an essential addition to medical libraries as well as an invaluable reference for general physicians, internists, rheumatologists, neurologists, cardiologists, nephrologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, and obstetricians.

Vascular Manifestations of Systemic Autoimmune Diseases

Vascular Manifestations of Systemic Autoimmune Diseases Book
Author : Ronald A. Asherson,Ricard Cervera,Douglas A. Triplett,Steven B. Abramson
Publisher : CRC Press
Release : 2001-01-25
ISBN : 1420040391
Language : En, Es, Fr & De

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Book Description :

Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all

The Antiphospholipid Syndrome II

The Antiphospholipid Syndrome II Book
Author : Ronald A. Asherson,R. Cervera,J.C. Piette,Yehuda Shoenfeld
Publisher : Gulf Professional Publishing
Release : 2002-09-05
ISBN : 9780444509871
Language : En, Es, Fr & De

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Book Description :

This book provides the reader with a comprehensive overview of the Antiphospholipid syndrome. One of the most important advances in rheumatology and connective tissue diseases of the last decade. It provides an explanation for many previously undefined conditions with no clear pathogenesis encompassing all subspeculations in internal medicine as well as obstetrics. Clotting problems leading to strokes and myocardial infarctions (in younger people) as well as a large variety of other syndromes such as chorea, hyproadrenalism, pulmonary problems are now being understood.

Antiphospholipid Syndrome

Antiphospholipid Syndrome Book
Author : Alena Bulikova
Publisher : BoD – Books on Demand
Release : 2012-04-20
ISBN : 9535105264
Language : En, Es, Fr & De

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Book Description :

The antiphospholipid syndrome has been described for the first time by Graham Hughes in 1983 as a condition connected with thromboses or foetal losses and antiphospholipid antibodies presence. Form that time there has been a great progress in knowledge, including antiphospholipid antibodies characterisation, their probable and also possible action, clinical manifestations, laboratory detection and treatment possibilities . This book provides a wide spectrum of clinical manifestations through Chapters written by well known researchers and clinicians with a great practical experience in management of diagnostics or treatment of antiphospholipid antibodies' presence.

ANTIPHOSPHOLIPID ANTIBODY SYNDROME PRESENTING AS STROKE U2013 SIGNIFICANCE OF APTT

ANTIPHOSPHOLIPID ANTIBODY SYNDROME PRESENTING AS STROKE U2013 SIGNIFICANCE OF APTT Book
Author : Abhas Kumar
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The antiphospholipid syndrome is a systemic autoimmune disease defined by thrombotic or obstetrical events that occur in patients with persistent antiphospholipid antibodies. Anti-phospholipid antibodies (APLA) are a part of heterogeneous group of circulating serum polyclonal immunoglobulins (IgG, IgM, IgA or mixed) that bind negatively charged or neutral phospholipid component of cell membranes and cause increased tendency to venous or arterial thrombosis. Persistently positive APS requires that laboratory tests be conducted at least 12 weeks apart.

The Neurologic Involvement in Systemic Autoimmune Diseases

The Neurologic Involvement in Systemic Autoimmune Diseases Book
Author : Anonim
Publisher : Elsevier
Release : 2004-11-05
ISBN : 9780080479682
Language : En, Es, Fr & De

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Book Description :

Systemic autoimmune diseases can affect both the central and peripheral nervous systems in a myriad of ways and through a heterogeneous number of mechanisms leading to many different clinical manifestations. As a result, neurological complications of these disorders can result in significant morbidity and mortality. Advances in the diagnosis, laboratory investigations, and management of these conditions has placed an increasing burden on the practicing clinician to correctly assess and treat these patients. This volume of the Handbook of the Systemic Autoimmune Diseases will help the clinician and researcher better understand the current concepts of nervous system involvement from systemic autoimmune disorders, recognize current approaches to diagnosis and treatment, current controversies, and areas that need significant research efforts. It is believed that providing this approach in a single volume will facilitate its use as a frequent resource for all those caring for or investigating these patients and their diseases. Each chapter follows a consistent outline to provide the reader with important and useful information in an easy-to-navigate manner and is also liberally referenced to provide more primary source material for further consideration. The standardized approach to each chapter will allow the reader to be able to compare and contrast more efficiently the neurological complications of the autoimmune diseases discussed.

Anti phospholipid Syndrome at Cairo University Hospitals

Anti phospholipid Syndrome at Cairo University Hospitals Book
Author : Zaghloul Fatma,Ali Abd El- Hamid Azza,Shaaban Abdl-Monem Amel
Publisher : LAP Lambert Academic Publishing
Release : 2015-10-07
ISBN : 9783659785054
Language : En, Es, Fr & De

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Book Description :

Antiphospholipid syndrome (APS), is a disorder of the immune system that is characterised by excessive clotting of blood in the arteries and veins, and/or certain complications of pregnancy as recurrent miscarriages, unexplained fetal death, or premature birth with the presence of antiphospholipid antibodies like anti-cardiolipin or lupus anticoagulant antibodies in the blood.Antiphospholipid syndrome is classified into primary and secondary; the primary is referred to the condition that found in pregnant women with neither clinical nor laboratory evidence of another definite autoimmune condition. While, secondary APS is the condition that, associated with other diseases, mainly systemic lupus erythematosus (SLE), and also can be found in other autoimmune diseases, occasionally during infections, malignancies and in response to some types of drugs

Immune System Diseases Advances in Research and Treatment 2011 Edition

Immune System Diseases  Advances in Research and Treatment  2011 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-01-09
ISBN : 146492905X
Language : En, Es, Fr & De

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Book Description :

Immune System Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immune System Diseases. The editors have built Immune System Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immune System Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Immune System Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Heart in Systemic Autoimmune Diseases

The Heart in Systemic Autoimmune Diseases Book
Author : Fabiola Atzeni,Andrea Dorea,Mike Nurmohamed,Paolo Pauletto
Publisher : Elsevier
Release : 2017-02-11
ISBN : 0444636692
Language : En, Es, Fr & De

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Book Description :

The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics. Presents an impressive body of well ordered information on the topic of cardiovascular diseases and their relationship to autoimmune illness Highlights key references Summarizes the experience of a selected panel of distinguished physician-scientists who are actively involved in the field of cardiovascular disease and systemic autoimmunity