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Antiphospholipid Syndrome In Systemic Autoimmune Diseases

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Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Antiphospholipid Syndrome in Systemic Autoimmune Diseases Book
Author : Ricard Cervera,Gerard Espinosa,Munther Khamashta
Publisher : Elsevier
Release : 2016-06-18
ISBN : 0444636560
Language : En, Es, Fr & De

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Book Description :

Antiphospholipid Syndrome in Systemic Autoimmune Diseases, Second Edition provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations in both the thrombotic and non-thrombotic manifestations of this important disease. Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy, and memory loss, and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, and from psychiatry to orthopedics. Brings the reader up-to-date and allows easy access to individual topics in one place Written by a respected panel of distinguished physicians/scientists actively involved in the field of Antiphospholipid Syndrome Includes box summaries at the end of each chapter that highlight important topics Gives up-to-date, basic knowledge and a modern approach to diagnosis and therapy Provides a comprehensive review of this major disease Includes information on treatment options available

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases

Reproductive and Hormonal Aspects of Systemic Autoimmune Diseases Book
Author : Michael Lockshin,D. Ware Branch
Publisher : Gulf Professional Publishing
Release : 2006
ISBN : 0444518010
Language : En, Es, Fr & De

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Book Description :

This volume of the Handbook of Systemic Autoimmune Diseases series represents a medical collaboration focusing primarily on female aspects of rheumatic diseases. This collaboration recognizes the need to understand and optimally manage the care of women with autoimmune conditions that may affect their reproduction and hormonal status. This handbook will prove useful to clinicians and researchers alike. It covers practical points, ranging from which anti-rheumatic medications are safe in pregnancy to how to counsel women with scleroderma contemplating pregnancy. * Authors share an academic interest in the unique relationship between being a woman and having an autoimmune disease * Touches on controversial topics, such as the mechanism of antiphospholipid-related fetal loss and whether or not non-steroidal anti-inflammatory agents should be used in pregnancy * Includes critical and balanced reviews of the controversial association between autoimmune disease and female infertility

The Skin in Systemic Autoimmune Diseases

The Skin in Systemic Autoimmune Diseases Book
Author : Piercarlo Sarzi-Puttini
Publisher : Elsevier
Release : 2006-01-26
ISBN : 9780080461922
Language : En, Es, Fr & De

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Book Description :

This book represents the state-of-the-art in the field of skin and autoimmune rheumatic diseases. It covers systematically a growing and multifaceted topic which is of great importance in the clinical practice. It also serves as a sharp educational tool as each chapter provides summaries and specific highlights to key references cited into the text. The pathophysiological link between skin involvement and autoimmunity has been explained in detail, as well as diagnostic and therapeutic aspects. This book yields an impressive body of well ordered information which summarizes the experience of a selected panel of distinguished physicians and scientists actively involved in the field of skin immunology and systemic autoimmunity. * Written by a respected panel of distinguished physician-scientists actively involved in the field of skin immunology and systemic autoimmunity * Box summaries at the end of each chapter highlight important topics * Up-to-date basic knowledge as well as modern approach to diagnosis and therapy

The Antiphospholipid Syndrome II

The Antiphospholipid Syndrome II Book
Author : Ronald A. Asherson,R. Cervera,J.C. Piette,Yehuda Shoenfeld
Publisher : Gulf Professional Publishing
Release : 2002-09-05
ISBN : 9780444509871
Language : En, Es, Fr & De

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Book Description :

This book provides the reader with a comprehensive overview of the Antiphospholipid syndrome. One of the most important advances in rheumatology and connective tissue diseases of the last decade. It provides an explanation for many previously undefined conditions with no clear pathogenesis encompassing all subspeculations in internal medicine as well as obstetrics. Clotting problems leading to strokes and myocardial infarctions (in younger people) as well as a large variety of other syndromes such as chorea, hyproadrenalism, pulmonary problems are now being understood.

Antiphospholipid Syndrome in Systemic Autoimmune Diseases

Antiphospholipid Syndrome in Systemic Autoimmune Diseases Book
Author : R. Cervera,Ricard Cervera
Publisher : Elsevier
Release : 2009-04-01
ISBN : 9780080932347
Language : En, Es, Fr & De

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Book Description :

Antiphospholipid syndrome is an autoimmune disease that causes abnormal blood clots. It is now recognized as a major cause of common conditions, including stroke, heart attack, miscarriage, epilepsy and memory loss and as such is gaining recognition in all branches of medicine, from obstetrics to cardiology, from psychiatry to orthopedics. This book provides an overview of our current understanding of this major disease. It includes the latest information on the new pathogenetic mechanisms involved as well as clinical manifestations in both “the thrombotic and “non-thrombotic manifestations of this important disease. * Comprehensive review of this major disease * Includes information on treatment options available

Autoimmune Diseases

Autoimmune Diseases Book
Author : Munther A Khamashta,Manuel Ramos-Casals
Publisher : Springer
Release : 2011-05-27
ISBN : 9780857293572
Language : En, Es, Fr & De

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Book Description :

Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

Antiphospholipid Syndrome

Antiphospholipid Syndrome Book
Author : Doruk Erkan,Silvia S. Pierangeli
Publisher : Springer Science & Business Media
Release : 2012-05-19
ISBN : 1461431948
Language : En, Es, Fr & De

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Book Description :

The International Congress on Antiphospholipid Antibodies is held every three years to discuss the recent advances and future directions in Antiphospholipid Syndrome (APS). This volume collects the scientific highlights and new findings about APS that were generated from the most recent 13th Congress, held in Galveston, Texas in 2010. Chapters were written by an internationally-distinguished group of scientists from the point-of-view of multiple specialty areas. Each chapter was written in a uniform and systematic basis to present the latest evidence-based research, including the basic science of APS, task force reports from the Congress on controversial aspects of APS, and future directions of APS research. This book will appeal to all clinicians involved in the treatment and management of APS patients, to residents in a variety of medical subspecialties, and to research scientists interested in a better understanding of this complex and evolving disease.

Autoimmune Diseases

Autoimmune Diseases Book
Author : Munther A Khamashta,Manuel Ramos-Casals
Publisher : Springer Science & Business Media
Release : 2011-05-26
ISBN : 9780857293589
Language : En, Es, Fr & De

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Book Description :

Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus Book
Author : Caroline Gordon,David Isenberg
Publisher : Oxford University Press
Release : 2016-03-10
ISBN : 0191059706
Language : En, Es, Fr & De

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Book Description :

Systemic Lupus Erythematosus (often abbreviated to SLE or lupus) is a systemic autoimmune disease that can affect any part of the body, causing the immune system to attack the body's cells and tissue, and resulting in inflammation and tissue damage. This new addition to the Oxford Rheumatology Library series provides a practical approach to the assessment and management of patients with this complex, multisystem autoimmune disease to improve the diagnosis and treatment of the disease and its complications. It provides comprehensive but easy to assimilate reading for consultant rheumatologists, dermatologists, nephrologists, obstetricians and other specialists and their trainees, interested GPs, specialist nurses, and clinical trial teams both in hospitals and contract research organizations.

Antiphospholipid Antibody Syndrome

Antiphospholipid Antibody Syndrome Book
Author : Pier Luigi Meroni
Publisher : Springer
Release : 2014-11-20
ISBN : 3319110446
Language : En, Es, Fr & De

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Book Description :

This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

The Association of Other Autoimmune Diseases in Patients With Thyroid Autoimmunity

The Association of Other Autoimmune Diseases in Patients With Thyroid Autoimmunity Book
Author : Alessandro Antonelli,Salvatore Benvenga
Publisher : Frontiers Media SA
Release : 2018-11-02
ISBN : 2889456250
Language : En, Es, Fr & De

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Book Description :

Autoimmune thyroid diseases (AITD) are T cell-mediated organ-specific autoimmune disorders resulting from an immune dysregulation leading to a thyroid immune attack (Antonelli and Benvenga). Graves’ disease and Hashimoto’s thyroiditis are the two main clinical presentations of AITD, and their clinical hallmarks are thyrotoxicosis and hypothyroidism, respectively. In many cases, AITD may be associated in the same patient with other organ-specific autoimmune attacks (such as in the case of type II autoimmune polyglandular syndrome, or type I diabetes, etc). Furthermore, AITD and thyroid function abnormalities have been frequently described in patients with systemic rheumatologic autoimmune diseases. Conversely, patients affected with the above mentioned autoimmune disorders are more frequently affected by AITD. In this Research Topic, constituted by nineteen papers, we review and discuss new evidence about the association of other autoimmune diseases in patients with AITD. Among other organ-specific autoimmune disorders, the associations of AITD with chronic autoimmune gastritis (Cellini et al.), vitiligo (Baldini E et al.), lichen (Guarneri et al.), psoriasis (Ruffilli et al.), myasthenia gravis (Lopomo and Berrih-Aknin) and glomerulopathies (Santoro et al.) have been treated. Also the associations of AITD, in systemic autoimmune diseases have been treated (as Sjögren’s syndrome, Baldini C et al.; systemic sclerosis, Fallahi et al.; systemic lupus erythematosus, Ferrari et al.; Antiphospholipid syndrome, Versini; sarcoidosis, Fazzi et al.; the autoimmune/inflammatory syndrome induced by adjuvants, Watad et al.; rheumatoid arthritis, Bliddal et al.; Hepatitis C Virus and mixed cryoglobulinemia, Ferri et al.; and, psoriathic arthritis, Ruffilli et al.). Furthermore peculiar aspects associated with post partum thyroiditis have been reviewed too (Di Bari et al., Le Donne et al.). The exact pathogenetic mechanisms underlying the above reported associations are not completely known. It has been hypothesized that the influence of genetic (Coppedè), and environmental factors (Antonelli and Benvenga), could lead to the onset of autoimmune phenomena in different organs in the same subject, characterized by predominance of a Th1 immune pattern at the beginning, and in the active phase of these disorders. In conclusion, an association of other autoimmune diseases in patients with thyroid autoimmunity has been shown, and this Research Topic provides an extensive update of the literature, and suggests interesting points for new investigations.

Connective Tissue Disease

Connective Tissue Disease Book
Author : Dario Roccatello,Lorenzo Emmi
Publisher : Springer
Release : 2016-04-09
ISBN : 331924535X
Language : En, Es, Fr & De

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Book Description :

In this volume devoted to systemic lupus erythematosus (SLE) and Sjögren syndrome, leading specialists from different disciplines present the latest research findings on many aspects of the diseases and describe the most recent trends in treatment, such as the “treat to target” approach. Both basic science and clinical medicine are addressed, with emphasis on the most promising clinical and laboratory-based studies. The coverage is comprehensive in scope, encompassing, for example, epidemiology, pathogenesis, autoantibodies and biomarkers, disease manifestations, involvement of different organs or systems, relationships with other disorders, biological therapy of SLE, and systemic treatment of Sjögren syndrome. Readers will find this first volume of Connective Tissue Disease to be an excellent source of information on the current understanding of, and clinical approach to, SLE and Sjögren syndrome that clearly conveys the progress made in recent years.

ANTIPHOSPHOLIPID ANTIBODY SYNDROME PRESENTING AS STROKE U2013 SIGNIFICANCE OF APTT

ANTIPHOSPHOLIPID ANTIBODY SYNDROME PRESENTING AS STROKE U2013 SIGNIFICANCE OF APTT Book
Author : Abhas Kumar
Publisher : Unknown
Release : 2017
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The antiphospholipid syndrome is a systemic autoimmune disease defined by thrombotic or obstetrical events that occur in patients with persistent antiphospholipid antibodies. Anti-phospholipid antibodies (APLA) are a part of heterogeneous group of circulating serum polyclonal immunoglobulins (IgG, IgM, IgA or mixed) that bind negatively charged or neutral phospholipid component of cell membranes and cause increased tendency to venous or arterial thrombosis. Persistently positive APS requires that laboratory tests be conducted at least 12 weeks apart.

Systemic Lupus Erythematosus and Antiphospholipid Syndrome

Systemic Lupus Erythematosus and Antiphospholipid Syndrome Book
Author : Pier Luigi Meroni,George C. Tsokos
Publisher : Frontiers Media SA
Release : 2019-08-12
ISBN : 2889459799
Language : En, Es, Fr & De

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Book Description :

Download Systemic Lupus Erythematosus and Antiphospholipid Syndrome book written by Pier Luigi Meroni,George C. Tsokos, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Sj gren s Syndrome in Clinical Practice

Sj  gren   s Syndrome in Clinical Practice Book
Author : Graham Hughes,Shirish Sangle,Simon Bowman
Publisher : Springer
Release : 2014-06-17
ISBN : 3319060597
Language : En, Es, Fr & De

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Book Description :

Sjögren’s syndrome is now considered pivotal in the spectrum of auto-immune disorders. It presents in a variety of guises, including fatigue, aches and pains, food and other allergies and not surprisingly is frequently misdiagnosed as, for example, ‘fibromyalgia, ‘M.E.’, glandular fever etc. It also frequently overlaps with other auto-immune conditions such as hypothyroidism (Hashimotos), Hughes Syndrome and coeliac disease. Diagnosis is especially important as it usually responds to treatment, notably with quinine derivatives (Plaquenil).

Antiphospholipid Syndrome

Antiphospholipid Syndrome Book
Author : Alena Bulikova
Publisher : BoD – Books on Demand
Release : 2012-04-20
ISBN : 9535105264
Language : En, Es, Fr & De

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Book Description :

The antiphospholipid syndrome has been described for the first time by Graham Hughes in 1983 as a condition connected with thromboses or foetal losses and antiphospholipid antibodies presence. Form that time there has been a great progress in knowledge, including antiphospholipid antibodies characterisation, their probable and also possible action, clinical manifestations, laboratory detection and treatment possibilities . This book provides a wide spectrum of clinical manifestations through Chapters written by well known researchers and clinicians with a great practical experience in management of diagnostics or treatment of antiphospholipid antibodies' presence.

Vascular Manifestations of Systemic Autoimmune Diseases

Vascular Manifestations of Systemic Autoimmune Diseases Book
Author : Ronald A. Asherson,Ricard Cervera,Douglas A. Triplett,Steven B. Abramson
Publisher : CRC Press
Release : 2001-01-25
ISBN : 9781420040395
Language : En, Es, Fr & De

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Book Description :

Not too long ago, it was thought that inflammation of blood vessels was the sole manifestation of systemic autoimmune diseases. Today, however, we know that disorders of coagulation, injuries to both neutrophils and endothelial cells, and certain lipids and amino acids are all intricately involved in the development of vascular disease. How are all

Women s Health in Autoimmune Diseases

Women s Health in Autoimmune Diseases Book
Author : Shefali Khanna Sharma
Publisher : Springer
Release : 2020-05-28
ISBN : 9789811501135
Language : En, Es, Fr & De

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Book Description :

This book focuses on conveying autoimmune disease expertise to gynecologists and other clinicians, allowing them to approach the treatment of each disease in a pragmatic manner. Each chapter reviews the current literature on treatments for autoimmune diseases, especially under special circumstances like pregnancy; rating disease severity; and providing practical guidelines based on the current state of knowledge. How autoimmune diseases affect fertility, and how to best prepare patients with these diseases for pregnancy, is also addressed. Unfortunately the current literature does not provide effective guidelines. This book addresses that shortcoming, and will help clinicians to implement appropriate treatments, while also outlining possible alternatives in order to provide effective treatment for women living with autoimmune diseases. It also explores important issues concerning autoimmune diseases in women such as: lupus nephritis, vasculitis, Sjogren’s syndrome, anti phospholipid syndrome and systemic sclerosis, and their potential effects on unborn children. Given its scope, the book offers a valuable reference guide for Practicing Clinicians, Rheumatologists and Gynecologists, among others.

The Antiphospholipid Syndrome

The Antiphospholipid Syndrome Book
Author : Ronald A. Asherson
Publisher : CRC Press
Release : 2018-05-04
ISBN : 1351094025
Language : En, Es, Fr & De

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Book Description :

Written by the foremost researchers in the field, this book gathers together in a single source the many important clinical associations of antiphospholipid antibodies. Antibody-related clotting mechanisms and their relationship to conditions such as recurrent strokes, chorea, multi infarct dementias, a variety of spinal syndromes, Addison's Disease, recurrent miscarriages, and many more are discussed in depth. The importance of these antibodies in 'Primary,' 'Secondary,' and 'Catastrophic' Antiphospholipid Syndrome is highlighted. Each chapter is devoted to a specific internal system and the clinical effects this syndrome has on that system. This authoritative book is an essential addition to medical libraries as well as an invaluable reference for general physicians, internists, rheumatologists, neurologists, cardiologists, nephrologists, endocrinologists, gastroenterologists, pulmonologists, dermatologists, and obstetricians.

Anti phospholipid Syndrome at Cairo University Hospitals

Anti phospholipid Syndrome at Cairo University Hospitals Book
Author : Zaghloul Fatma,Ali Abd El- Hamid Azza,Shaaban Abdl-Monem Amel
Publisher : LAP Lambert Academic Publishing
Release : 2015-10-07
ISBN : 9783659785054
Language : En, Es, Fr & De

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Book Description :

Antiphospholipid syndrome (APS), is a disorder of the immune system that is characterised by excessive clotting of blood in the arteries and veins, and/or certain complications of pregnancy as recurrent miscarriages, unexplained fetal death, or premature birth with the presence of antiphospholipid antibodies like anti-cardiolipin or lupus anticoagulant antibodies in the blood.Antiphospholipid syndrome is classified into primary and secondary; the primary is referred to the condition that found in pregnant women with neither clinical nor laboratory evidence of another definite autoimmune condition. While, secondary APS is the condition that, associated with other diseases, mainly systemic lupus erythematosus (SLE), and also can be found in other autoimmune diseases, occasionally during infections, malignancies and in response to some types of drugs