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Principles and Applications of Antimicrobial Nanomaterials

Principles and Applications of Antimicrobial Nanomaterials Book
Author : Joseph L. Graves Jr
Publisher : Elsevier
Release : 2021-08-19
ISBN : 0128232633
Language : En, Es, Fr & De

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Book Description :

Principles and Applications of Antimicrobial Nanomaterials introduces the reader to the microbial world, antimicrobial nanomaterials, how microbial evolution works, and how knowledge of these areas can facilitate the development of sustainable antimicrobials. Due to the widespread occurrence of multidrug-resistant microbes, there is an increasing interest in the use of novel nanostructured materials as antimicrobials. This book is designed to help researchers from fields such as materials science, nanoscience, and nanoengineering who are attempting to develop these antimicrobial materials. Provides crucial background in microbiology and microbial evolution to help researchers design experiments that can produce sustainable results Offers detailed coverage on the antimicrobial properties of different types of nanomaterials Discusses the major challenges of using nanomaterials for antimicrobial applications

Recent Progress in Antimicrobial Nanomaterials

Recent Progress in Antimicrobial Nanomaterials Book
Author : Ana María Díez-Pascual
Publisher : MDPI
Release : 2021-01-20
ISBN : 3039439596
Language : En, Es, Fr & De

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Book Description :

Based on a fundamental understanding of the interaction between bacteria and nanomaterials, this book highlights the latest research on the antimicrobial properties of nanomaterials and provides an invaluable blueprint for improving the antimicrobial performance of devices and products. This book introduces the reader to the progress being made in the field, followed by an outline of applications in different areas. Various methods and techniques of synthesis and characterization are detailed. The content provides insight into the ongoing research, current trends, and technical challenges in this rapidly progressing field. Therefore, this book is highly suitable for materials scientists, engineers, biologists, and technologists.

Antimicrobial Nanoarchitectonics

Antimicrobial Nanoarchitectonics Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2017-06-22
ISBN : 0323527345
Language : En, Es, Fr & De

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Book Description :

Antimicrobial Nanoarchitectonics: From Synthesis to Applications brings together recent research in antimicrobial nanoparticles, specifically in the sustained and controlled delivery of antimicrobials. Particular attention is given to i) reducing the side effects of antibiotics, ii) increasing the pharmacological effect, and iii) improving aqueous solubility and chemical stability of different antimicrobials. In addition, antimicrobial nanoparticles in drug delivery are discussed extensively. The book also evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections. It is an important reference resource for materials scientists and bioengineers who want to learn how nanomaterials are used in antimicrobial therapy. Provides readers with the information necessary to select the appropriate bionanomaterial to solve particular infection problems Includes case studies, showing how particular bionanomaterials have been used to cure infections Explains the central role that nanotechnology plays in modern antimicrobial therapy Evaluates the pros and cons of using nanostructured biomaterials in the prevention and eradication of infections

Antimicrobial Nanomaterials Derived from Natural Products A Review

Antimicrobial Nanomaterials Derived from Natural Products  A Review Book
Author : Anonim
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Modern medicine has relied heavily on the availability of effective antibiotics to manage infections and enable invasive surgery. With the emergence of antibiotic-resistant bacteria, novel approaches are necessary to prevent the formation of biofilms on sensitive surfaces such as medical implants. Advances in nanotechnology have resulted in novel materials and the ability to create novel surface topographies. This review article provides an overview of advances in the fabrication of antimicrobial nanomaterials that are derived from biological polymers or that rely on the incorporation of natural compounds with antimicrobial activity in nanofibers made from synthetic materials. Furthermore, the availability of these novel materials will contribute to ensuring that the current level of medical care can be maintained as more bacteria are expected to develop resistance against existing antibiotics.

Nanobiomaterials in Antimicrobial Therapy

Nanobiomaterials in Antimicrobial Therapy Book
Author : Alexandru Grumezescu
Publisher : William Andrew
Release : 2016-03-08
ISBN : 0323428878
Language : En, Es, Fr & De

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Book Description :

Nanobiomaterials in Antimicrobial Therapy presents novel antimicrobial approaches that enable nanotechnology to be used effectively in the treatment of infections. This field has gained a large amount of interest over the last decade, in response to the high resistance of pathogens to antibiotics. Leading researchers from around the world discuss the synthesis routes of nanobiomaterials, characterization, and their applications as antimicrobial agents. The books covers various aspects: mechanisms of toxicity for inorganic nanoparticles against bacteria; the development of excellent carriers for the transport of a high variety of antimicrobials; the use of nanomaterials to facilitate both diagnosis and therapeutic approaches against infectious agents; strategies to control biofilms based on enzymes, biosurfactants, or magnetotactic bacteria; bacterial adhesion onto polymeric surfaces and novel materials; and antimicrobial photodynamic inactivation. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians. A methodical approach to this highly relevant subject for researchers, practitioners and students working in biomedical, biotechnological and engineering fields A valuable guide to recent scientific progress and the latest application methods Proposes novel opportunities and ideas for developing or improving technologies in nanomedicine and nanobiology

Antimicrobial Nanomaterials Derived from Natural Products u2014 A Review

Antimicrobial Nanomaterials Derived from Natural Products u2014 A Review Book
Author : Anonim
Publisher : Unknown
Release : 2016
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Modern medicine has relied heavily on the availability of effective antibiotics to manage infections and enable invasive surgery. With the emergence of antibiotic-resistant bacteria, novel approaches are necessary to prevent the formation of biofilms on sensitive surfaces such as medical implants. Advances in nanotechnology have resulted in novel materials and the ability to create novel surface topographies. This review article provides an overview of advances in the fabrication of antimicrobial nanomaterials that are derived from biological polymers or that rely on the incorporation of natural compounds with antimicrobial activity in nanofibers made from synthetic materials. Furthermore, the availability of these novel materials will contribute to ensuring that the current level of medical care can be maintained as more bacteria are expected to develop resistance against existing antibiotics.

Nanomaterials for Environmental Protection

Nanomaterials for Environmental Protection Book
Author : Boris I. Kharisov,Oxana Vasilievna Kharissova,H. V. Rasika Dias
Publisher : John Wiley & Sons
Release : 2014-08-27
ISBN : 1118845544
Language : En, Es, Fr & De

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Book Description :

This book is divided into four main sections thoroughly analyzing the use of nanomaterials for water, air and soil solutions, and emphasizing environmental risks. Providing background on nanomaterials' two-decade study, it discusses the characterization and application of unconventional disinfectants, called antimicrobial nanomaterials, which fall into three categories and, while seemingly harmless, have potential hazards if applied improperly. Special attention is given to the process of remediation, synthetics techniques, and properties of nanomaterials, with examples to which new and trained readers in the field can relate and understand. an interdisciplinary approach, aimed at scientists in physical chemistry, nanotechnology, and environmental sciences includes applications of non-conventional techniques in environmental protection furthers the development of applied nanoscience and nanotechnology suggests new industrial projects and university courses addressing nanotechnology in and for the environment includes applications for water, air and soil protection

Antibacterial Activity of Nanomaterials

Antibacterial Activity of Nanomaterials Book
Author : Ana María Díez-Pascual
Publisher : MDPI
Release : 2018-09-14
ISBN : 3038970492
Language : En, Es, Fr & De

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Book Description :

This book is a printed edition of the Special Issue "Antibacterial Activity of Nanomaterials" that was published in Nanomaterials

Functionalized Nanomaterials for the Management of Microbial Infection

Functionalized Nanomaterials for the Management of Microbial Infection Book
Author : Rabah Boukherroub,Sabine Szunerits,Djamel Drider
Publisher : William Andrew
Release : 2016-12-14
ISBN : 032341737X
Language : En, Es, Fr & De

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Book Description :

Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. Provides the information users need to integrate antibacterial nanoparticles into future treatments Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection

Biological and Pharmaceutical Applications of Nanomaterials

Biological and Pharmaceutical Applications of Nanomaterials Book
Author : Polina Prokopovich
Publisher : CRC Press
Release : 2015-06-26
ISBN : 1482250179
Language : En, Es, Fr & De

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Book Description :

Biological and Pharmaceutical Applications of Nanomaterials presents the findings of cutting-edge research activities in the field of nanomaterials, with a particular emphasis on biological and pharmaceutical applications. Divided into four sections—nanomaterials for drug delivery, antimicrobial nanomaterials, nanomaterials in biosensors, and safety of nanomaterials—this book: Covers topics such as stimuli-responsive nanostructured silica matrixes, gold nanoparticles, and liposomes for targeting drug delivery and dental applications Describes the use of nanocarriers and nanoparticles as cancer and peptide therapeutics, the influence of surface characteristics on microbial adhesion, and the latest developments in antimicrobial nanostructured polymers for medical applications Discusses recent advances in nanodiagnostic techniques for infectious agents, chromogenic biosensors for pathogen detection, electrochemical biosensors for detecting DNA damage and genotoxicity, and molecular imaging with quantum dots including surface modifications by polymers for biosensing applications Featuring contributions from field experts and researchers in industry and academia, Biological and Pharmaceutical Applications of Nanomaterials provides state-of-the-art information on nanomaterials and their use in drug delivery, infection control, and biomedicine.

Materials for Biomedical Engineering Bioactive Materials for Antimicrobial Anticancer and Gene Therapy

Materials for Biomedical Engineering  Bioactive Materials for Antimicrobial  Anticancer  and Gene Therapy Book
Author : Alexandru Grumezescu,Alina-Maria Holban
Publisher : Elsevier
Release : 2019-06-28
ISBN : 0128184361
Language : En, Es, Fr & De

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Book Description :

Materials for Biomedical Engineering: Bioactive Materials for Antimicrobial, Anticancer, and Gene Therapy offers an up-to-date perspective on recent research findings regarding the application and use of these materials for disease treatment and prevention. Various types of currently investigated bioactive materials, including therapeutic nanostructures and antimicrobial hydrogels are discussed, as are their properties, impact and future role in therapeutic applications. The book will be extremely useful for new researchers who want to explore more information on the use of bioactive materials or for more experienced researchers who are interested in new trends and specific applications. Provides knowledge on the range of bioactive materials available, enabling the reader to make optimal materials selection decisions Contains detailed information on current and proposed applications of the latest bioactive materials to empower readers to design innovative products and processes Presents a strong emphasis on chemistry and the physico-chemical characterization of these materials and their application in antimicrobial, anticancer and gene therapy

Nanostructures for Antimicrobial and Antibiofilm Applications

Nanostructures for Antimicrobial and Antibiofilm Applications Book
Author : Ram Prasad,Busi Siddhardha,Madhu Dyavaiah
Publisher : Springer Nature
Release : 2020-05-12
ISBN : 3030403378
Language : En, Es, Fr & De

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Book Description :

In the pursuit of technological advancement in the field of biotechnology and pharmaceutical industries to counteract health issues, bacterial infections remain a major cause of morbidity and mortality. The ability of bacterial pathogens to form biofilms further agglomerates the situation by showing resistance to conventional antibiotics. To overcome this serious issue, bioactive metabolites and other natural products were exploited to combat bacterial infections and biofilm-related health consequences. Natural products exhibited promising results in vitro, however; their efficacy in in vivo conditions remain obscured due to their low-solubility, bioavailability, and biocompatibility issues. In this scenario, nanotechnological interventions provide a multifaceted platform for targeted delivery of bioactive compounds by slow and sustained release of drug-like compounds. The unique physico-chemical properties, biocompatibility and eco-friendly nature of bioinspired nanostructures has revolutionized the field of biology to eradicate microbial infections and biofilm-related complications. The green-nanotechnology based metal and metal oxide nanoparticles and polymeric nanoparticles have been regularly employed for antimicrobial and antibiofilm applications without causing damage to host tissues. The implications of these nanoparticles toward achieving sustainability in agriculture by providing systemic resistance against a variety of phytopathogens therefore plays crucial role in growth and crop productivity. Also the advent of smart and hybrid nanomaterials such as metal-based polymer nanocomposites, lipid-based nanomaterials and liposomes have the inherent potential to eradicate bacterial biofilm-related infections in an efficient manner. The recent development of carbon-based nanomaterials such as carbon nanotubes (CNTs) and silica based nanomaterials such as mesoporous silica nanoparticles (MSNs) also exploit a target of dreadful healthcare conditions such as cancer, immunomodulatory diseases, and microbial infections, as well as biofilm-related issues owing to their stability profile, biocompatibility, and unique physio-chemical properties. Recently novel physical approaches such as photothermal therapy (PTT) and antimicrobial photodynamic therapy (aPDT) also revolutionized conventional strategies and are engaged in eradicating microbial biofilm-related infections and related health consequences. These promising advancements in the development of novel strategies to treat microbial infections and biofilm-related multidrug resistance (MDR) phenomenon may provide new avenues and aid to conventional antimicrobial therapeutics.

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy Book
Author : Anton Ficai,Alexandru Mihai Grumezescu
Publisher : Elsevier
Release : 2017-05-29
ISBN : 0323461514
Language : En, Es, Fr & De

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Book Description :

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Nanotoxicity

Nanotoxicity Book
Author : Susai Rajendran,Anita Mukherjee,Tuan Anh Nguyen,Chandraiah Godugu,Ritesh K. Shukla
Publisher : Elsevier
Release : 2020-04-09
ISBN : 012819944X
Language : En, Es, Fr & De

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Book Description :

Nanotoxicity: Prevention, and Antibacterial Applications of Nanomaterials focuses on the fundamental concepts for cytotoxicity and genotoxicity of nanomaterials. It sheds more light on the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media. The book provides good guidance for toxic prevention methods and management in the manufacture/application/disposal. The book also discusses the potential applications of nanomaterials-based antibiotics. The potential toxic effects of nanomaterials result not only from the type of base materials, but also from their size/ ligands/surface chemical modifications. This book discusses why different classes of nanomaterials display toxic properties, and what can be done to mitigate this toxicity. It also explores how nanomaterials are being used as antimicrobial agents, being used to purify air and water, and counteract a range of infectious diseases. This is an important reference for materials scientists, environmental scientists and biomedical scientists, who are seeking to gain a greater understanding of how nanomaterials can be used to combat toxic agents, and how the toxicity of nanomaterials themselves can best be mitigated. Explains the underlying phenomena and fundamental mechanisms through which nanomaterials interact with organisms and physiological media Outlines major methods for mitigating and prevention of nanotoxicity Discusses the applications of nanomaterials-based antibiotics

Functional Hybrid Nanomaterials for Environmental Remediation

Functional Hybrid Nanomaterials for Environmental Remediation Book
Author : Ahmad Fauzi Ismail,Pei Sean Goh
Publisher : Royal Society of Chemistry
Release : 2021-09-24
ISBN : 1839165294
Language : En, Es, Fr & De

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Book Description :

Functional and structural nanomaterials are emerging materials that display interesting physical and chemical properties because of their size and surface area to volume ratio. Applications for these materials include uses in removing pollutants from the environment. Looking at the current state-of-the-art as well as future trends in the use of nanomaterials for tackling environmental issues this book covers everything from the synthesis and characterisation of these materials to their use in the removal of specific contaminants. Functional Hybrid Nanomaterials for Environmental Remediation is a useful resource both for nanomaterial scientists interested in the real world application of hybrid nanomaterials and for environmental chemists and environmental engineers interested in novel materials for environmental remediation.

Interfaces Between Nanomaterials and Microbes

Interfaces Between Nanomaterials and Microbes Book
Author : Munishwar Nath Gupta,Sunil Kumar Khare,Rajeshwari Sinha
Publisher : CRC Press
Release : 2021-06-24
ISBN : 1000345017
Language : En, Es, Fr & De

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Book Description :

Nanomaterials are becoming ubiquitous; microbes similarly are everywhere. This book focuses on various ways the diverse nanomaterials interact with microbial communities and implications of such interactions. Both toxicity and beneficial effects of nanomaterial-microbe interactions have been covered. This includes areas such as fate and bioavailability of nanomaterials in environments, microbial synthesis of nanomaterials and antimicrobial action of nanomaterials. Fairly comprehensive but with narrow focus, the book provides useful insights into these interactions which need to be factored in while designing nanoscience based new technologies.

Advances in Polymeric Nanomaterials for Biomedical Applications

Advances in Polymeric Nanomaterials for Biomedical Applications Book
Author : Anil Kumar Bajpai,Rajesh Kumar Saini
Publisher : Elsevier
Release : 2021-03-26
ISBN : 0128146583
Language : En, Es, Fr & De

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Book Description :

Advances in Polymeric Nanomaterials for Biomedical Applications examines advanced polymer synthetic strategies for developing novel biomaterials for use in medicine. With a strong focus on fundamentals and structure, the authors also explore their fabrication, along with their current and potential biomedical applications. The book begins with a look at the fundamentals of polymeric nanomaterials and their properties and then discusses the design of biomaterials and their applications in drug delivery. Further chapters explore important applications, such as imaging and regenerative medicine, including current challenges and future trends. This valuable resource is especially useful for materials and polymer scientists, and bioengineers wishing to broaden their knowledge of polymeric nanobiomaterials. Covers the complete spectrum of polymer nanomaterials used in biomedical applications Includes various applications, such as drug delivery, gene delivery, bio-imaging, tissue engineering and regenerative medicine, anti-microbial agents, and neuroscience Explores fundamental correlations between structures, properties and applications, as well as synthetic strategies for polymer nanomaterials

Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer

Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer Book
Author : Saravanan, Muthupandian,Gopinath, Venkatraman,Deekonda, Karthik
Publisher : IGI Global
Release : 2021-02-12
ISBN : 1799850501
Language : En, Es, Fr & De

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Book Description :

Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.

Silver Nanoparticles for Antibacterial Devices

Silver Nanoparticles for Antibacterial Devices Book
Author : Huiliang Cao
Publisher : CRC Press
Release : 2017-05-18
ISBN : 1315353474
Language : En, Es, Fr & De

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Book Description :

Since the potential toxicity of silver nanoparticles (Ag NPs) has raised serious concerns in the biomaterials and biomedical engineering community, Silver Nanoparticles for Antibacterial Devices: Biocompatibility and Toxicity brings together the synthesis, the physicochemical properties and the biological actions of Ag NPs, as well as the clinical demands for fabricating antibacterial medical devices, discussing how to suppress the side effects of nanomaterials and how to impart to them the selective toxicity. This book presents the two primary paradigms that have emerged in probing the antibacterial applications of Ag NPs, i.e. the active attacking releasing way and the conservative defending approach by taking advantage of various short-range actions; it shows readers how the ways in which Ag NPs have behaved can be engineered purposively. With contributions from leading international experts and extensive references listed in each chapter, this volume provides the general principles on controlling the physicochemical behaviors of nanomaterials and managing their toxicity risks.

Preclinical Evaluation of Antimicrobial Nanodrugs

Preclinical Evaluation of Antimicrobial Nanodrugs Book
Author : Juan Bueno
Publisher : Springer Nature
Release : 2020-05-08
ISBN : 3030438554
Language : En, Es, Fr & De

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Book Description :

Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.