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Anti Cancer Treatments And Cardiotoxicity

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Anti Cancer Treatments and Cardiotoxicity

Anti Cancer Treatments and Cardiotoxicity Book
Author : Patrizio Lancellotti,Jose L. Zamorano,Maurizio Galderisi
Publisher : Academic Press
Release : 2016-06-01
ISBN : 9780128025093
Language : En, Es, Fr & De

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Book Description :

Download Anti Cancer Treatments and Cardiotoxicity book written by Patrizio Lancellotti,Jose L. Zamorano,Maurizio Galderisi, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Anticancer Treatments and Cardiotoxicity

Anticancer Treatments and Cardiotoxicity Book
Author : Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi
Publisher : Academic Press
Release : 2016-11-11
ISBN : 0128026472
Language : En, Es, Fr & De

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Book Description :

Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment

Cardiotoxicity

Cardiotoxicity Book
Author : Wenyong Tan
Publisher : BoD – Books on Demand
Release : 2018-11-14
ISBN : 1789842379
Language : En, Es, Fr & De

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Book Description :

Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.

Holland Frei Cancer Medicine

Holland Frei Cancer Medicine Book
Author : Robert C. Bast, Jr.,Carlo M. Croce,William N. Hait,Waun Ki Hong,Donald W. Kufe,Martine Piccart-Gebhart,Raphael E. Pollock,Ralph R. Weichselbaum,Hongyang Wang,James F. Holland
Publisher : John Wiley & Sons
Release : 2017-03-10
ISBN : 111900084X
Language : En, Es, Fr & De

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Book Description :

Holland-Frei Cancer Medicine, Ninth Edition, offers a balanced view of the most current knowledge of cancer science and clinical oncology practice. This all-new edition is the consummate reference source for medical oncologists, radiation oncologists, internists, surgical oncologists, and others who treat cancer patients. A translational perspective throughout, integrating cancer biology with cancer management providing an in depth understanding of the disease An emphasis on multidisciplinary, research-driven patient care to improve outcomes and optimal use of all appropriate therapies Cutting-edge coverage of personalized cancer care, including molecular diagnostics and therapeutics Concise, readable, clinically relevant text with algorithms, guidelines and insight into the use of both conventional and novel drugs Includes free access to the Wiley Digital Edition providing search across the book, the full reference list with web links, illustrations and photographs, and post-publication updates

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio oncology

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio oncology Book
Author : Imteyaz Qamar,Pawan Kumar Maurya
Publisher : Academic Press
Release : 2022-06-07
ISBN : 0323904629
Language : En, Es, Fr & De

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Book Description :

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications—arrhythmias, heart failure, and even death. Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications

Cardiotoxicity of Novel Cancer Therapies

Cardiotoxicity of Novel Cancer Therapies Book
Author : Edith Pituskin
Publisher : Unknown
Release : 2013
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Breast cancer is the most common malignancy among females, and the second leading cause of cancer death among Canadian women. Despite improved survival, both short and long term detrimental effects have been observed with both novel and conventional anti-cancer therapies. In particular, the effects of cancer therapy on the cardiovascular system, or 'cardiotoxicity', are increasingly recognized in terms of morbidity and mortality. Subtle or 'sub-clinical' early effects of anti-cancer therapies on cardiac structures may remain undetected, conveying potentially devastating longer-term effects. The overarching theme of this thesis is to examine the short and long-term effects of a novel anti-cancer therapy, trastuzumab, on left ventricular (LV) morphology and function in breast cancer patients. Two studies were undertaken; study #1 was a cross-sectional study of 17 female breast cancer survivors exposed to trastuzumab-based chemotherapy, examining LV remodeling and exercise capacity. We found that early breast cancer patients had significant alterations in left ventricular geometry and impairment of cardiorespiratory function four years following exposure to trastuzumab-based chemotherapy. The second study was performed to examine the effects of three months of standard heart failure therapy, consisting of angiotensin-converting enzyme inhibitor or beta-blocker vs placebo, on LV remodeling in breast cancer patients receiving trastuzumab-based therapy. The major finding was that that standard heart failure pharmacotherapy appeared to be effective in attenuating LV dysfunction associated with trastuzumab-based therapy. When compared to patients randomized to the pharmacotherapy group, significant decline in left ventricular ejection fraction occurred in the placebo group.

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio oncology

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio oncology Book
Author : Imteyaz Qamar,Pawan Kumar Maurya
Publisher : Elsevier
Release : 2022-06-15
ISBN : 0323904610
Language : En, Es, Fr & De

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Book Description :

Cardiovascular Toxicity and Therapeutic Modalities Targeting Cardio-Oncology: From Basic Research to Advanced Study analyzes the emerging the field of cardio-oncology, reviewing recent advancements in the field, discussing how to monitor and treat cancer survivors for cardiotoxicity, and identifying potential cardiac side effects in novel cancer therapies. By adopting a translational approach, the book first comprehensively covers the basic science, mechanisms and concepts, which is followed by advanced state-of-art of cardio-oncology. Other sections cover tyrosine kinase inhibitors, Anthracyclines, and biomarkers in cardiotoxicity induced by chemotherapeutic drugs, noninvasive cardiovascular imaging techniques, radiotherapy induced cardiovascular, and more. Anti-cancer treatment is associated with serious cardiovascular adverse events, including arterial and pulmonary hypertension, supraventricular and ventricular arrhythmias, systolic and diastolic cardiac dysfunction and coronary artery disease. Progress in cancer therapy over the past decades improved long-term survival but increased cancer therapy-related cardiotoxicity. Both traditional chemotherapeutic agents and newer therapies have demonstrated profound cardiovascular toxicities. It is important to understand the mechanisms of these toxicities to establish strategies for the prevention and management of complications-arrhythmias, heart failure, and even death. Adopts a translational approach and comprehensively covers the basic science, mechanisms and concepts of cardio-oncology Outlines the current knowledge of biomarkers in cancer therapy-related cardiotoxicity Provides an understanding of the mechanisms of cardiovascular toxicity of various therapies that may lead to the identification of novel targets to reduce vascular complications

Handbook of Cancer Treatment Related Symptoms and Toxicities E Book

Handbook of Cancer Treatment Related Symptoms and Toxicities E Book Book
Author : Vamsidhar Velcheti,Salman R Punekar
Publisher : Elsevier Health Sciences
Release : 2021-01-28
ISBN : 032367299X
Language : En, Es, Fr & De

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Book Description :

Early recognition and management of adverse effects of cancer treatments are essential for optimal care of patients with cancer, and drastically different approaches are required for different physiologic reactions. Handbook of Cancer Treatment-Related Symptoms and Toxicities is a focused, one-stop resource that enables clinicians to quickly find up-to-date, reliable information needed at the point of care. The high-yield approach prioritizes the most common toxicities associated with cancer treatment, and concise, templated chapters offer fast access to information needed in day-to-day practice. Presents a user-friendly overview of cancer treatment-related symptoms and toxicities management in a practical, easy-to-use format, allowing you to quickly find information in one convenient, concise resource. Covers systemic and radiation therapies, including chemotherapy, immunotherapy, targeted therapies, and radiation therapy, detailing symptoms of each toxicity to confirm your diagnosis. Overviews pharmacologic and non-pharmacologic approaches to symptom management. Offers recommendations for mitigating toxicities in high-risk patients. Discusses key topics such as management of infusion reactions, when the need for biopsy is warranted, and the unique challenges posed by novel immunotherapies.

Cardio Oncology

Cardio Oncology Book
Author : Gretchen G. Kimmick,Daniel J. Lenihan,Douglas B. Sawyer,Erica L. Mayer,Dawn L. Hershman
Publisher : Springer
Release : 2017-04-11
ISBN : 3319430963
Language : En, Es, Fr & De

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Book Description :

Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics: • Cardiac complications in patients receiving cancer therapy • The treatment of cancer in patients with cardiovascular disease • The treatment of cardiovascular disease in patients with cancer When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.

Cardio Oncology

Cardio Oncology Book
Author : Roberta A. Gottlieb,Puja K Mehta
Publisher : Academic Press
Release : 2016-11-26
ISBN : 0128035536
Language : En, Es, Fr & De

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Book Description :

Cardio-Oncology: Principles, Prevention and Management is a clinical volume that focuses on the basic science of cardio-oncology, addresses cardiotoxicity as a consequence of cancer therapy, and discusses prevention, diagnosis and management of cardiovascular disease in patients with cancer. This comprehensive volume presents unique perspectives ranging from basic science to clinical medicine in the field of cardio-oncology. It would be a valuable resource for cardiologists, oncologists, internists, and pediatricians caring for patients with cancer who have cardiovascular risk factors, as well as for cardio-oncology researchers. Covers basic science of cardio-oncology to provide readers with the necessary background Addresses cardiotoxicity related to current cancer therapeutic modalities Discusses diagnostic and management approaches of patients with underlying cardiac risk factors as well as otherwise healthy cancer patients

Cardiac Management of Oncology Patients

Cardiac Management of Oncology Patients Book
Author : Gonzalo Baron Esquivias,Riccardo Asteggiano
Publisher : Springer
Release : 2015-05-25
ISBN : 3319158082
Language : En, Es, Fr & De

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Book Description :

This book is designed for clinical cardiologists and other physicians working with cardiac patients, where specific specialized teams of cardio-oncologists are not available and who are called to perform a clinical consultation to evaluate both the cardiac condition and the eligibility for chemotherapy or radiotherapy treatment, and to evaluate if a cancer treatment produces toxic effects on a patient treated with chemo or radiotherapy and if appearance of new symptoms is due to this treatment. In recent years, progress in oncologic therapy has resulted in important developments and the prognostic improvement of patients with malignancy. The cornerstone of chemotherapy are the anthracyclines (and the analogue Mitoxantrone), that are direct cellular toxic agents and that are among the most powerful anti-neoplastic drugs, but their cardiac toxicity is well known. Significant breakthroughs in cancer therapy have also been achieved with the introduction of signalling inhibitors, such as VEGF inhibitors, HERB2 inhibitors or TK inhibitors used alone or in combination with direct cellular toxic drugs. However, these signalling inhibitors may interact also with cardiovascular signalling and therefore may have functional or structural effects on the myocardium. This can be permanent or reversible, with impairment of the global conditions and important side effects, and increase both morbidity and mortality and worsening of quality of life. Chemotherapy and radiotherapy can have acute detrimental effects that can be present for years after treatment and that can lead to cardiac consequences also after long periods of no clinic sequelae. Patient numbers with cancer problems will dramatically increase in the next years and thus every cardiologist will need to have the correct information and the skills to manage these situations in the correct way. This book will provide these tools for them.

Surface Guided Radiation Therapy

Surface Guided Radiation Therapy Book
Author : Jeremy David Page Hoisak,Adam Brent Paxton,Benjamin James Waghorn,Todd Pawlicki
Publisher : CRC Press
Release : 2020-02-13
ISBN : 0429951809
Language : En, Es, Fr & De

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Book Description :

Surface Guided Radiation Therapy provides a comprehensive overview of optical surface image guidance systems for radiation therapy. It serves as an introductory teaching resource for students and trainees, and a valuable reference for medical physicists, physicians, radiation therapists, and administrators who wish to incorporate surface guided radiation therapy (SGRT) into their clinical practice. This is the first book dedicated to the principles and practice of SGRT, featuring: Chapters authored by an internationally represented list of physicists, radiation oncologists and therapists, edited by pioneers and experts in SGRT Covering the evolution of localization systems and their role in quality and safety, current SGRT systems, practical guides to commissioning and quality assurance, clinical applications by anatomic site, and emerging topics including skin mark-less setups. Several dedicated chapters on SGRT for intracranial radiosurgery and breast, covering technical aspects, risk assessment and outcomes. Jeremy Hoisak, PhD, DABR is an Assistant Professor in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Hoisak’s clinical expertise includes radiosurgery and respiratory motion management. Adam Paxton, PhD, DABR is an Assistant Professor in the Department of Radiation Oncology at the University of Utah. Dr. Paxton’s clinical expertise includes patient safety, motion management, radiosurgery, and proton therapy. Benjamin Waghorn, PhD, DABR is the Director of Clinical Physics at Vision RT. Dr. Waghorn’s research interests include intensity modulated radiation therapy, motion management, and surface image guidance systems. Todd Pawlicki, PhD, DABR, FAAPM, FASTRO, is Professor and Vice-Chair for Medical Physics in the Department of Radiation Medicine and Applied Sciences at the University of California, San Diego. Dr. Pawlicki has published extensively on quality and safety in radiation therapy. He has served on the Board of Directors for the American Society for Radiology Oncology (ASTRO) and the American Association of Physicists in Medicine (AAPM).

Cardiac Complications of Cancer Therapy

Cardiac Complications of Cancer Therapy Book
Author : Anecita P. Fadol
Publisher : Unknown
Release : 2013-01-01
ISBN : 9781935864240
Language : En, Es, Fr & De

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Book Description :

Cardiac complications of anticancer therapy represent an emerging clinical issue in both established chemotherapeutics as well as novel molecular therapies. As a result, healthcare providers are under greater pressure to be vigilant in evaluating patients with cancer for acute and chronic or late physical effects of cancer therapy some of which could be life-threatening. Cardiac Complications of Cancer Therapy, edited by Anecita P. Fadol, PhD, RN, FNP-BC, FAANP, provides you with the essentials of clinical management of the most common cardiac complications of cancer therapy. While you can find a multitude of literature on the management of cardiac problems, including both texts and journal articles, no other clinical reference book on the current market is written for nurses and midlevel providers and examines both the complexity of cardiac problems in conjunction with a cancer diagnosis. Describing the assessment and management of common cardiac problems, chapters in this quick-reference guide examine issues such as cardiovascular anatomy, the development of cardiotoxicity and the management of cardiomyopathy in patients with cancer, targeted therapies and cardiomyopathy, acute coronary syndromes in patients with cancer, cardiac inflammatory conditions and cardiac tamponade in patients with cancer, hypertension in patients with cancer, heart failure in patients with cancer, screening and management of cardiovascular risk factors in cancer survivors, and much more.

Pediatric Cancer Survivors

Pediatric Cancer Survivors Book
Author : Karen Wonders,Brittany Stout
Publisher : BoD – Books on Demand
Release : 2017-06-07
ISBN : 9535132199
Language : En, Es, Fr & De

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Book Description :

Pediatric cancer develops in 1 to 500 children. Typically, the type of cancers that develop in children is different than those that develop in adults, in that they are often the result of a DNA mutation rather than environmental or lifestyle risk factors. Leukemia, brain and central nervous system tumors, and neuroblastomas are the most common cancer types in child populations. Children tend to respond better to anticancer treatments, including chemotherapy and radiation. However, long-term side effects are common in children, often requiring follow-up care and lifestyle intervention for the rest of their lives. The percentage of 5-year survivors was over 50% for the most common cancers. This suggests that a majority of cancers in this population are highly survivable. As such, research should focus on aspects of survivorship for these individuals. This book will explore issues related to pediatric cancer and their associated treatments.

Clinical Cases in Cardio Oncology

Clinical Cases in Cardio Oncology Book
Author : Atooshe Rohani
Publisher : Springer Nature
Release : 2021-04-26
ISBN : 3030711552
Language : En, Es, Fr & De

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Book Description :

This latest book in the Clinical Cases in Cardiology series presents a variety of commonly and rarely encountered cases associated with ​cardio-oncology. It explores the history of the discipline and each case described features concise practically orientated information on how to appropriately carry out physical examinations and utilize diagnostic tests including electrocardiography and monoclonal antibodies. Practically focused guidance is also provided on how to apply therapeutic techniques and the latest management strategies appropriately. Clinical Cases in Cardio-Oncology provides a concise practically applicable guide of how to diagnose and treat a range of conditions associated with ​cardio-oncology, making it a critical addition to the literature on the topic and a valuable resource for all medical practitioners who encounter these patients in their day-to-day practice.

Cancer and the Heart

Cancer and the Heart Book
Author : Michael S. Ewer,Edward T. H. Yeh, M.D.
Publisher : PMPH-USA
Release : 2013
ISBN : 9781607950400
Language : En, Es, Fr & De

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Book Description :

The book begins with the basic science behind the medical applications of the knowledge: cardiovascular biology, pathways, and their relationship to cancer treatment and principles of chemotherapy and immunotherapy. The second section consists of an overview and classification of anti-cancer drugs and a look at their cardiotoxicity. The third section looks at cardiac imaging in the cancer patient, including cardiac ultrasound, Doppler imaging, nuclear imaging, magnetic resonance imaging, and computed tomography in the cancer patient. In section four, management of cardiac disease in the cancer patient is discussed, including cardiac rhythm disturbances and heart failure. Cardiac emergencies and interventions are described as is preoperative assessment of the cancer patient for non- cardiovascular surgery. The final section includes a range of topics such as the pericardium, cardiovascular effects of endocrine treatments, primary cardiac tumors and malignancies of the myocardium and pericardium. Cardiac monitoring during clinical trials and pulmonary concerns are also addressed, as are psychosocial, social, economic, and legal issues of the cancer patient with heart disease.

Recent Advances in Cardiotoxicity Testing

Recent Advances in Cardiotoxicity Testing Book
Author : Tamer M. A. Mohamed,Javid Moslehi,Jonathan Satin
Publisher : Frontiers Media SA
Release : 2022-01-05
ISBN : 2889719545
Language : En, Es, Fr & De

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Book Description :

Download Recent Advances in Cardiotoxicity Testing book written by Tamer M. A. Mohamed,Javid Moslehi,Jonathan Satin, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Cancer Treatment

Cancer Treatment Book
Author : Letícia Rangel
Publisher : BoD – Books on Demand
Release : 2013-05-09
ISBN : 9535110985
Language : En, Es, Fr & De

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Book Description :

Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections: i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches; ii) Section 2: Combinatorial strategies to fight cancer: Surgery, radiotherapy, backytherapy, chemotherapy, and hyperthermia; iii) Section 3: The immunotherapy of cancer; iv) Section 4: Multidisciplinarity in cancer therapy: nutrition and beyond; v) Section 5: Supportive care for cancer patients; vi) Section 6: Perspectives in cancer biology and modeling. Ultimately, we hope this book can enlighten important issues involved in the management of cancer, summarizing the state-of-the-art knowledge regarding the disease control and treatment; thus, providing means to improve the overall care of patients that daily battle against this potentially lethal condition.

Practical Cardio Oncology

Practical Cardio Oncology Book
Author : Susan F. Dent
Publisher : CRC Press
Release : 2019-08-30
ISBN : 1351583565
Language : En, Es, Fr & De

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Book Description :

This book takes a holistic view of the treatment of cardio-oncology patients, from evaluating those at high risk of developing cardio-toxicity, guidance for monitoring and managing patients during therapy to cardiac care of cancer survivors. Throughout, this book utilizes the latest research and guidance to offer advice on treatment strategy as well as practical elements of such as training, cardio-oncology nursing, patient education and how to establish a cardio-oncology unit. This book focuses on the practical knowledge and skills key to successful collaboration between cardiologists and oncologists to achieve the optimum cardiac care for cancer patients. Key Features Focuses on the practical elements of cardio-oncology care Outlines the importance and process of setting up a cardio-oncology unit and cardio-oncology fellowships Provides advice and guidance on the set up and common pit falls of coordinating care for cardio-oncology patients Outlines current guidelines and potential future directions for the field of cardio-oncology

Annals of Oncology

Annals of Oncology Book
Author : European Society for Medical Oncology
Publisher : Springer
Release : 2013-12-14
ISBN : 1489973052
Language : En, Es, Fr & De

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Book Description :

Download Annals of Oncology book written by European Society for Medical Oncology, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.