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Analytical Chemistry For Assessing Medication Adherence

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Analytical Chemistry for Assessing Medication Adherence

Analytical Chemistry for Assessing Medication Adherence Book
Author : Sangeeta Tanna,Graham Lawson
Publisher : Elsevier
Release : 2016-04-14
ISBN : 012805459X
Language : En, Es, Fr & De

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Book Description :

The lack of adherence to medication is a growing public health problem worldwide and is costing many patients their good health and healthcare systems billions of dollars. A new volume in the Emerging Issues in Analytical Chemistry series, Analytical Chemistry for Assessing Medication Adherence introduces the concept of medication adherence/compliance and reports international perspectives on medication adherence while highlighting its importance. It then describes the opportunities for analytical chemistry to assess medication adherence and thereby provide an evidence base for clinicians to improve patient health outcomes. The authors highlight the strengths and weaknesses of each of the analytical techniques cited in addition to categorizing the findings in terms of the biological samples used to assess adherence and identifying methods to extract biological samples prior to analysis. The final chapter provides the authors’ perspective in this area, emphasising the importance of medication optimization for individual patients. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Thomas, Brian F. and ElSohly, Mahmoud. The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations, 9780128046463, December 2015. Hackney, Anthony C. Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice, 9780128092064, March 2016. Rao, Vikram, Knight, Rob, and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, forthcoming September 2016. Farsalinos, Konstantinos, et al. Analytical Assessment of e-Cigarettes: From Contents to Chemical and Particle Exposure Profiles, 9780128112410, forthcoming November 2016. Surveys the strengths, weaknesses, and appropriateness of existing instruments and techniques and points the way toward a program of therapeutic optimization Brings together data scattered amongst professional journals and other sources in a single convenient volume Presents the problem of adherence and the authors’ evaluation of possible solutions based on the analysis of patient bio-samples

Detection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid Book
Author : Robert M. White,Christine M. Moore
Publisher : Elsevier
Release : 2018-02-23
ISBN : 012814596X
Language : En, Es, Fr & De

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Book Description :

Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes discussed include amphetamines, cannabinoids, cocaine, opiates, phencyclidine, cannabimimetics, and miscellaneous drugs. This practical guide helps users turn knowledge into practice, moving logically from an outline of the problem, to the evaluation of the appropriateness of oral fluid as a test medium, and finally to a consideration of detection methods and their validation and employment. Compares different collection and testing systems to assist readers involved in clinical or forensic practice in selecting oral fluid as the matrix of choice Provides a sound basis for the detection of drugs and their metabolites in oral fluid and the interpretation of both positive and negative Places the need, or lack thereof, for specimen validity testing and confirmation testing in context with the purposes of oral fluid testing Describes drugs and drug classes that can be tested, along with useful information on a patient/donor’s drug status

Doping Performance Enhancing Drugs and Hormones in Sport

Doping  Performance Enhancing Drugs  and Hormones in Sport Book
Author : Anthony C Hackney
Publisher : Elsevier
Release : 2017-11-23
ISBN : 0128134437
Language : En, Es, Fr & De

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Book Description :

Doping, Performance-Enhancing Drugs, and Hormones in Sport: Mechanisms of Action and Methods of Detection examines the biochemistry and bioanalytical aspects of performance-enhancing drugs (PEDs) and other questionable procedures used by athletes to enhance performance. The book informs the specialist of emerging knowledge and techniques and allows the non-specialist to grasp the underlying science and current practice of the discipline. With clear and compelling language appropriate for a broad spectrum of readers, this book provides background on prevalence, types of agents, their actual or supposed benefits, and their negative effects on health. The technical aspects of detection are discussed, followed by a discussion of why detection is a problematic and still-evolving science. To facilitate comprehension, each chapter is organized in a uniform way with six sections: (1) standard medical uses, (2) why the drugs are used by athletes, (3) biological mechanism of action, (4) what research says about efficacy in improving performance, (5) major health side effects from use and abuse in sport, and 6) concluding key points. Presents the scientific concepts of how performance enhancers work, how they are used, and how they are detected and masked from detection Features language that is neither simplistic to scientists nor too sophisticated for a large, diverse global audience Provides a short “close-up” in each chapter to illustrate key topics that engage, entertain, and create a novel synthesis of thought

Smokeless Tobacco Products

Smokeless Tobacco Products Book
Author : Anonim
Publisher : Elsevier
Release : 2020-01-23
ISBN : 0128181591
Language : En, Es, Fr & De

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Book Description :

Smokeless Tobacco Products: Characteristics, Usage, Health Effects, and Regulatory Implications, a title in the Emerging Issues in Analytical Chemistry series, presents an overview of research on the second most dangerous tobacco product. This book presents findings on public health risks emanating from the complex interaction between smokeless tobacco products and their users. It covers the key components of assessment and provides insight into scientific and public health considerations. The book does not take a simplistic condemnatory position, but rather conceptualizes tobacco use in terms of graduated public health danger and harm reduction. The book begins by introducing smokeless tobacco, its history of use, marketing, and implications for public health. It then continues with coverage of epidemiology, pathology and clinical implications, addiction, and treatment, and includes laboratory studies of human use. The following section explains the chemistry, biochemical mechanisms of carcinogenesis, and role of plant cultivation and manufacturing in toxicity. Finally, the book concludes by addressing regulatory considerations, the scientific basis of regulations, and the role of these products in harm reduction for smokers. This is the first resource of its kind to cover these topics together and in language appropriate to both specialists in the research community and informed persons responsible for legislative, funding, and public health matters in the community at large. Brings attention to smokeless tobacco product use and its association with addiction and disease Considers smokeless tobacco use historically and currently, as well as its place in a future harm-reduction conceptualization of tobacco Written by a distinguished, internationally recognized group of tobacco researchers from academia, independent research organizations, and the federal government with expertise in the many and various disciplines covered

Analytical Methods for Biomass Characterization and Conversion

Analytical Methods for Biomass Characterization and Conversion Book
Author : David C. Dayton,Thomas D. Foust
Publisher : Elsevier
Release : 2019-11-05
ISBN : 0128156066
Language : En, Es, Fr & De

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Book Description :

Analytical Methods for Biomass Characterization and Conversion is a thorough resource for researchers, students and professors who investigate the use of biomass for fuels, chemicals and products. Advanced analytical chemistry methods and techniques can now provide detailed compositional and chemical measurements of biomass, biomass conversion process streams, intermediates and products. This volume from the Emerging Issues in Analytical Chemistry series brings together the current knowledge on each of these methods, including spectroscopic methods (Fourier Transform Infrared Spectroscopy, Near-infrared Spectroscopy, Solid State Nuclear Magnetic Resonance), pyrolysis (Gas Chromatography/Mass Spectrometry), Liquid Chromatography/High Performance Liquid Chromatography, Liquid Chromatography/Mass Spectrometry, and so on. Authors David C. Dayton and Thomas D. Foust show how these can be used for measuring biomass composition and for determining the composition of intermediates with regard to subsequent processing for biofuels, bio-chemicals and bio-based products. Covers the broad range of techniques and applications that have been developed and perfected in the last decade Highlights specific analyses required for understanding biomass conversion to select intermediates Provides references to seminal books, review articles and technical articles that go into greater depth, serving as a basis for further study

Particulates Matter

Particulates Matter Book
Author : Vikram Rao,William Vizuete
Publisher : Elsevier
Release : 2020-11-28
ISBN : 0128169052
Language : En, Es, Fr & De

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Book Description :

A title in the Emerging Issues in Analytical Chemistry series, Particulates Matter: Impact, Measurement, and Remediation of Airborne Pollutants provides the latest technical findings in the study of particulate matter (PM). It links these findings to awareness-raising and actionable schemes for legislated remediation and engineered solutions. Written in an engaging and informative manner, the book begins with a multi-disciplinary overview of the major sources and unique classes of PM, detection techniques, and their impact, including molecular changes resulting in health effects. It then goes one step further by proposing and examining the means to curtail and contain PM generation and ameliorate their impacts. Particulates Matter: Impact, Measurement, and Remediation of Airborne Pollutants offers a high-quality reference guide to PM that will greatly benefit technology leaders in environmental compliance groups, epidemiologists and other public health professionals focused on pollution and health, and researchers and scholars working in pollution, climate change, and urbanization. It may also be useful to advanced undergraduate and early graduate students in environmental sciences. Includes a summary of the current knowledge on nanoparticles as pollutants and their negative health effects Provides a framework for the evolution and maturation of air pollution characterization and mitigation Describes an integrated set of engineered solutions that account for the concatenated relationships between technology, policy, and society necessary for long-term success

Inhaled Pharmaceutical Product Development Perspectives

Inhaled Pharmaceutical Product Development Perspectives Book
Author : Anthony J. Hickey
Publisher : Elsevier
Release : 2017-11-23
ISBN : 0128123362
Language : En, Es, Fr & De

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Book Description :

Inhaled Pharmaceutical Product Development Perspectives: Challenges and Opportunities describes methods and procedures for consideration when developing inhaled pharmaceuticals, while commenting on product development strategies and their suitability to support regulatory submission. It bridges the gap between the aspirations of scientists invested in new technology development and the requirements that must be met for any new product. The book brings together emerging analytical and inhalation technologies, providing perspectives that illuminate formulation and device design, development, regulatory compliance, and practice. Focusing on underlying scientific and technical principles known to be acceptable from the current regulatory perspective, this monograph will remain useful as a high-level guide to inhaled product development for the foreseeable future. Discusses development strategies and best practices in the context of regulatory requirements Written by a broadly qualified expert drawing on the knowledge and critical opinions of key individuals in the field Includes a foreword by Charles G. Thiel

Endocrine Disrupting Chemicals induced Metabolic Disorders and Treatment Strategies

Endocrine Disrupting Chemicals induced Metabolic Disorders and Treatment Strategies Book
Author : Muhammad Sajid Hamid Akash,Kanwal Rehman,Muhammad Zaffar Hashmi
Publisher : Springer Nature
Release : 2020-08-04
ISBN : 3030459233
Language : En, Es, Fr & De

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Book Description :

This volume offers a detailed and comprehensive analysis of Endocrine Disrupting Chemicals (EDCs), covering their occurrence, exposure to humans and the mechanisms that lead to the parthogenesis of EDCs-induced metabolic disorders. The book is divided into three parts. Part I describes the physiology of the human endocrine system, with special emphasis on various types of metabolic disorders along with risk factors that are responsible for the development of these disorders. Part II addresses all aspects of EDCs, including their role in the induction of various risk factors that are responsible for the development of metabolic disorders. Part III covers up-to-date environmental regulatory considerations and treatment strategies that have been adopted to cure and prevent EDCs-induced metabolic disorders. This section will primarily appeal to clinicians investigating the causes and treatment of metabolic disorders. The text will also be of interest to students and researchers in the fields of Environmental Pharmacology and Toxicology, Environmental Pollution, Pharmaceutical Biochemistry, Biotechnology, and Drug Metabolism/Pharmacokinetics.

Exercise Sport and Bioanalytical Chemistry

Exercise  Sport  and Bioanalytical Chemistry Book
Author : Anthony C Hackney
Publisher : Elsevier
Release : 2016-03-14
ISBN : 0128096918
Language : En, Es, Fr & De

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Book Description :

A new volume in the Emerging Issues in Analytical Chemistry series, Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice focuses on the basic and applied aspects of energy metabolism in humans. Concise and scientific, yet intelligible to the nonscientist, the book consists of two parts. Part I, Introduction: Basics and Background, provides the biochemistry necessary to understand the rest of the book and describes analytical processes and results as an aid to grasping the science. Part II, Applications: Knowledge into Practice, explores measurement techniques for metabolism, energy expenditure of various activities, techniques that enhance expenditure, metabolic adaptation, foods and drugs that enhance expenditure, and the role of bioanalytical chemistry in future research in exercise and sport. Discussion of the benefits of exercise and practices for improving the capacity to perform exercise is illustrated by many useful and entertaining examples. This volume allows readers to come away with a grasp of the scientific concepts, how they are manifested in research techniques, and how the results of research can be applied in the real world of public health and personal development. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Thomas, Brian F. and ElSohly, Mahmoud. The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations, 9780128046463, December 2015. Tanna, Sangeeta and Lawson, Graham. Analytical Chemistry for Assessing Medication Adherence, 9780128054635, April 2016. Rao, Vikram, Knight, Rob, and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, forthcoming September 2016. Farsalinos, Konstantinos, et al. Analytical Assessment of e-Cigarettes: From Contents to Chemical and Particle Exposure Profiles, 9780128112410, forthcoming November 2016. Provides readers with the fundamental biochemistry and some elements of the physiology behind physical activity/exercise and describes the analytical techniques used to elucidate the science Written in clear, concise, compelling prose that is neither simplistic to scientists nor too sophisticated for a large, diverse global audience A one-page Close-Up in each chapter illustrates key topics to catch, engage, entertain, and create a novel synthesis of thought

Issues in Analysis Measurement Monitoring Imaging and Remote Sensing Technology 2013 Edition

Issues in Analysis  Measurement  Monitoring  Imaging  and Remote Sensing Technology  2013 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2013-06-20
ISBN : 1490105859
Language : En, Es, Fr & De

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Book Description :

Issues in Analysis, Measurement, Monitoring, Imaging, and Remote Sensing Technology: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Analysis and Measurement. The editors have built Issues in Analysis, Measurement, Monitoring, Imaging, and Remote Sensing Technology: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Analysis and Measurement in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Analysis, Measurement, Monitoring, Imaging, and Remote Sensing Technology: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Contemporary Practice in Clinical Chemistry

Contemporary Practice in Clinical Chemistry Book
Author : William Clarke,Mark Marzinke
Publisher : Academic Press
Release : 2020-06-11
ISBN : 0128158336
Language : En, Es, Fr & De

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Book Description :

Contemporary Practice in Clinical Chemistry, Fourth Edition, provides a clear and concise overview of important topics in the field. This new edition is useful for students, residents and fellows in clinical chemistry and pathology, presenting an introduction and overview of the field to assist readers as they in review and prepare for board certification examinations. For new medical technologists, the book provides context for understanding the clinical utility of tests that they perform or use in other areas in the clinical laboratory. For experienced laboratorians, this revision continues to provide an opportunity for exposure to more recent trends and developments in clinical chemistry. Includes enhanced illustration and new and revised color figures Provides improved self-assessment questions and end-of-chapter assessment questions

Clinical Challenges in Therapeutic Drug Monitoring

Clinical Challenges in Therapeutic Drug Monitoring Book
Author : William Clarke,Amitava Dasgupta
Publisher : Elsevier
Release : 2016-07-21
ISBN : 0128020520
Language : En, Es, Fr & De

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Book Description :

Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations. Offers busy clinicians, pathologists, and trainees a concise resource on the key aspects and critical issues in therapeutic drug monitoring Focuses on patient populations such as infants and children, pregnant women, elderly patients, and obese patients, who have special requirements in therapeutic drug monitoring Explores special topics in therapeutic drug monitoring including free drug monitoring and common immunoassay interference Explains how individual dosage adjustments can prevent drug toxicity for certain drugs within a narrow therapeutic window

Analytical Assessment of e Cigarettes

Analytical Assessment of e Cigarettes Book
Author : Konstantinos E. Farsalinos,I. Gene Gillman,Stephen S. Hecht,Riccardo Polosa,Jonathan Thornburg
Publisher : Elsevier
Release : 2016-11-16
ISBN : 0128112425
Language : En, Es, Fr & De

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Book Description :

A volume in the Emerging Issues in Analytical Chemistry series, Analytical Assessment of E-Cigarettes: From Contents to Chemical and Particle Exposure Profiles addresses the many issues surrounding electronic cigarettes in an unprecedented level of scientific detail. The plethora of product devices, formulations, and flavors, combined with the lack of industry standards and labeling requirements, quality control, and limited product oversight, has given rise to public concern about initiation of use and potential for adverse exposure and negative long-term health outcomes. This volume discusses how analytical methods can address these issues and support the manufacturing, labeling, distribution, testing, regulation, and monitoring for consistency of products with known chemical content and demonstrated performance characteristics. The book begins with the background on aerosol drug delivery services and e-cigarettes, constituents of nicotine-containing liquid dosing formulations, typical use scenarios and associated aerosol emissions, and chemical exposures and pharmacological and toxicological effect profiles, and then continues with descriptions of the analytical methods used to characterize the chemicals in formulations and emissions from e-cigarettes, including their stability, physical particle-size distribution and thermal degradation under commonly employed conditions of use. Analytical methods enabling detection of biomarkers of exposure and harm in complex biological matrices are discussed, with an emphasis on constituents or emissions of current medicinal interest or with potential to produce harm. Opportunities and challenges for analytical chemistry in supporting the continued development and use of safe and consistent dosage formulations as alternatives to tobacco products are also explored, with a concluding section describing an analytical approach to a risk-benefit assessment of e-cigarette use on human health. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Thomas, Brian F. and ElSohly, Mahmoud. The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations, 9780128046463, December 2015. Hackney, Anthony C. Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice, 9780128092064, March 2016. Tanna, Sangeeta and Lawson, Graham. Analytical Chemistry for Assessing Medication Adherence, 9780128054635, April 2016. Rao, Vikram; Knight, Rob; and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, September 2016. Discusses the chemistry and physics involved in aerosol production, inhalation, deposition, chemical exposure, and effect assessment Contains current information and state-of-the-science methods on e-cigarette emissions, exposures, and harm assessment Offers an authoritative, objective perspective from five of the most well-recognized scientists in their areas of expertise who have no personal stake in the e-cigarette industry or the opposition Includes a foreword written by Dr. Neal Benowitz

Applied Biological Engineering

Applied Biological Engineering Book
Author : Ganesh R. Naik
Publisher : BoD – Books on Demand
Release : 2012-03-23
ISBN : 9535104128
Language : En, Es, Fr & De

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Book Description :

Biological engineering is a field of engineering in which the emphasis is on life and life-sustaining systems. Biological engineering is an emerging discipline that encompasses engineering theory and practice connected to and derived from the science of biology. The most important trend in biological engineering is the dynamic range of scales at which biotechnology is now able to integrate with biological processes. An explosion in micro/nanoscale technology is allowing the manufacture of nanoparticles for drug delivery into cells, miniaturized implantable microsensors for medical diagnostics, and micro-engineered robots for on-board tissue repairs. This book aims to provide an updated overview of the recent developments in biological engineering from diverse aspects and various applications in clinical and experimental research.

Evidence Based Validation of Herbal Medicine

Evidence Based Validation of Herbal Medicine Book
Author : Pulok K. Mukherjee
Publisher : Elsevier
Release : 2022-07-12
ISBN : 0323984568
Language : En, Es, Fr & De

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Book Description :

Globalization in the context of drug development has increased the use of natural products worldwide. The trends in use of herbal medicine in therapeutics is becoming more popular and is still open to fascinating realms of research. ‘Evidence-Based Validation of Herbal Medicines’ brings together current thinking and practice in the areas of characterization and validation of natural products. This book describes different approaches and techniques for evaluating the quality, safety and efficacy of herbal medicine, particularly methods to assess their activity and understand the compounds responsible and their probable underlying mechanisms of action, which improve the level of understanding of various aspects on evaluation of natural products. This book is an effort to bring together the views, expertise and experiences of scientific experts in the field of medicinal plant research. This will be useful for the researcher to know more about the natural lead with their validation and also useful to exploit traditional medicines, leading to discovery and development of newer drugs through translational research with cutting edge technologies on natural remedies. This book will be an essential reading for the researchers whose professional life impinges on the use of natural resources. Includes state-of-the-art methods for detecting, isolating, and performing structure elucidation by degradation and spectroscopic techniques Highlights the trends in validation and value addition of herbal medicine with different scientific approaches used in therapeutics Contains several all-new chapters on topics such as traditional-medicine-inspired drug development to treat emerging viral diseases, medicinal plants in antimicrobial resistance, TLC bio profiling, botanicals as medicinal foods, bioprospecting and bioassay-guided isolation of medicinal plants, immunomodulators from medicinal plants, and more

A Comprehensive Guide to Toxicology in Preclinical Drug Development

A Comprehensive Guide to Toxicology in Preclinical Drug Development Book
Author : Ali S. Faqi
Publisher : Academic Press
Release : 2012-11-16
ISBN : 0123878152
Language : En, Es, Fr & De

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Book Description :

A Comprehensive Guide to Toxicology in Preclinical Drug Development is a resource for toxicologists in industry and regulatory settings, as well as directors working in contract resource organizations, who need a thorough understanding of the drug development process. Incorporating real-life case studies and examples, the book is a practical guide that outlines day-to-day activities and experiences in preclinical toxicology. This multi-contributed reference provides a detailed picture of the complex and highly interrelated activities of preclinical toxicology in both small molecules and biologics. The book discusses discovery toxicology and the international guidelines for safety evaluation, and presents traditional and nontraditional toxicology models. Chapters cover development of vaccines, oncology drugs, botanic drugs, monoclonal antibodies, and more, as well as study development and personnel, the role of imaging in preclinical evaluation, and supporting materials for IND applications. By incorporating the latest research in this area and featuring practical scenarios, this reference is a complete and actionable guide to all aspects of preclinical drug testing. Chapters written by world-renowned contributors who are experts in their fields Includes the latest research in preclinical drug testing and international guidelines Covers preclinical toxicology in small molecules and biologics in one single source

Methods and Advances in Traditional Chinese Medicine

Methods and Advances in Traditional Chinese Medicine Book
Author : David Yue-Wei Lee,Kai-Shun Bi,Gerald T. Pollard,Ronghua Dai
Publisher : Unknown
Release : 2016-03-07
ISBN : 9780128051610
Language : En, Es, Fr & De

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Book Description :

Methods and Advances in Traditional Chinese Medicine describes analytical chemistry methods used to characterize constituents of herbal remedies, explore their mechanisms of action singly and in concert, and support the clinical trials necessary to bring Traditional Chinese Medicine (TCM) into the mainstream of therapeutics. With recent advances in analytical instruments, molecular pharmacology, and genetics, it is now possible to investigate the bioactive molecules in a complex medicine on a rational basis. This book is the first to combine TCM with analytical chemistry methods toward this goal. The book begins with a brief history of TCM, consideration of its strengths and weaknesses, and a review of the literature on application of Western analytical methods. It continues with an examination of the concept of synergistic, multi-targeted action among components, followed by an analysis of how analytical chemistry and other methods are used to assure quality and uniformity of natural products within tolerable limits. It then addresses the complexity introduced by absorption, distribution, and metabolism of an already complex drug. The last chapter advocates a system biological approach as the way forward for drug discovery and development in TCM. Emphasizes the advantages of combining traditional medicine and modern tools for drug discovery and development Provides examples which source, identify, and assay materials; describe preparation of complex remedies and isolate or synthesize their components; characterize complexes and derivatives; and test selected entities for efficacy in animals and humans Explains the capabilities and limitations of various methods for evaluating test results, establishing the parameters of quality assurance

Federal Register

Federal Register Book
Author : Anonim
Publisher : Unknown
Release : 2012-03
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Federal Register book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Introduction to Pharmaceutical Analytical Chemistry

Introduction to Pharmaceutical Analytical Chemistry Book
Author : Stig Pedersen-Bjergaard,Bente Gammelgaard,Trine G. Halvorsen
Publisher : John Wiley & Sons
Release : 2019-02-11
ISBN : 111936275X
Language : En, Es, Fr & De

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Book Description :

The definitive textbook on the chemical analysis of pharmaceutical drugs – fully revised and updated Introduction to Pharmaceutical Analytical Chemistry enables students to gain fundamental knowledge of the vital concepts, techniques and applications of the chemical analysis of pharmaceutical ingredients, final pharmaceutical products and drug substances in biological fluids. A unique emphasis on pharmaceutical laboratory practices, such as sample preparation and separation techniques, provides an efficient and practical educational framework for undergraduate studies in areas such as pharmaceutical sciences, analytical chemistry and forensic analysis. Suitable for foundational courses, this essential undergraduate text introduces the common analytical methods used in quantitative and qualitative chemical analysis of pharmaceuticals. This extensively revised second edition includes a new chapter on chemical analysis of biopharmaceuticals, which includes discussions on identification, purity testing and assay of peptide and protein-based formulations. Also new to this edition are improved colour illustrations and tables, a streamlined chapter structure and text revised for increased clarity and comprehension. Introduces the fundamental concepts of pharmaceutical analytical chemistry and statistics Presents a systematic investigation of pharmaceutical applications absent from other textbooks on the subject Examines various analytical techniques commonly used in pharmaceutical laboratories Provides practice problems, up-to-date practical examples and detailed illustrations Includes updated content aligned with the current European and United States Pharmacopeia regulations and guidelines Covering the analytical techniques and concepts necessary for pharmaceutical analytical chemistry, Introduction to Pharmaceutical Analytical Chemistry is ideally suited for students of chemical and pharmaceutical sciences as well as analytical chemists transitioning into the field of pharmaceutical analytical chemistry.

CDER Report to the Nation

CDER     Report to the Nation Book
Author : Center for Drug Evaluation and Research (U.S.)
Publisher : Unknown
Release : 2022-09-29
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download CDER Report to the Nation book written by Center for Drug Evaluation and Research (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.