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An Introduction To Interdisciplinary Toxicology

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An Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology Book
Author : Carey N. Pope,Jing Liu
Publisher : Academic Press
Release : 2020-02-18
ISBN : 0128136030
Language : En, Es, Fr & De

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Book Description :

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from “simple molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology. Covers major topics and newer areas in toxicology, including nanotoxicology, Tox21, epigenetic toxicology, and organ-specific toxicity Includes a variety of perspectives to give a complete understanding of toxicology Written by specialists within each subject area, e.g., a chemical engineer, to ensure concepts are clearly explained

An Introduction to Interdisciplinary Toxicology

An Introduction to Interdisciplinary Toxicology Book
Author : Carey N. Pope,Jing Liu
Publisher : Academic Press
Release : 2020-02
ISBN : 0128136022
Language : En, Es, Fr & De

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Book Description :

An Introduction to Interdisciplinary Toxicology: From Molecules to Man integrates the various aspects of toxicology, from "simple" molecular systems, to complex human communities, with expertise from a spectrum of interacting disciplines. Chapters are written by specialists within a given subject, such as a chemical engineer, nutritional scientist, or a microbiologist, so subjects are clearly explained and discussed within the toxicology context. Many chapters are comparative across species so that students in ecotoxicology learn mammalian toxicology and vice versa. Specific citations, further reading, study questions, and other learning features are also included. The book allows students to concurrently learn concepts in both biomedical and environmental toxicology fields, thus better equipping them for the many career opportunities toxicology provides. This book will also be useful to those wishing to reference how disciplines interact within the broad field of toxicology.

Information Resources in Toxicology

Information Resources in Toxicology Book
Author : Steve Gilbert,Asish Mohapatra,Sol Bobst,Antoinette Hayes,Sara T. Humes
Publisher : Academic Press
Release : 2020-05-16
ISBN : 0128137258
Language : En, Es, Fr & De

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Book Description :

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children’s environmental health. Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources. Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles. Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals. Explores recent internet trends, web-based databases, and software tools in a section on the online environment. Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents. Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field.

Pharmacokinetics and Toxicokinetic Considerations Vol II

Pharmacokinetics and Toxicokinetic Considerations   Vol II Book
Author : Rakesh Kumar Tekade
Publisher : Academic Press
Release : 2022-02-17
ISBN : 0323913164
Language : En, Es, Fr & De

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Book Description :

Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists. Allows readers to systematically integrate up-to-date research findings into their laboratory work Presents focused explorations of bioanalytical methods for bioavailability and bioequivalence assessment Provides clinical applications of concepts

Environmental Systems Science

Environmental Systems Science Book
Author : Daniel Vallero
Publisher : Elsevier
Release : 2021-05-27
ISBN : 0128219440
Language : En, Es, Fr & De

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Book Description :

Environmental Systems Science: Theory and Practical Applications looks at pollution and environmental quality from a systems perspective. Credible human and ecological risk estimation and prediction methods are described, including life cycle assessment, feasibility studies, pollution control decision tools, and approaches to determine adverse outcome pathways, fate and transport, sampling and analysis, and cost-effectiveness. The book brings translational science to environmental quality, applying groundbreaking methodologies like informatics, data mining, and applications of secondary data systems. Multiple human and ecological variables are introduced and integrated to support calculations that aid environmental and public health decision making. The book bridges the perspectives of scientists, engineers, and other professionals working in numerous environmental and public health fields addressing problems like toxic substances, deforestation, climate change, and loss of biological diversity, recommending sustainable solutions to these and other seemingly intractable environmental problems. The causal agents discussed include physical, chemical, and biological agents, such as per- and polyfluoroalkyl substances (PFAS), SARS-CoV-2 (the COVID-19 virus), and other emerging contaminants. Provides an optimistic and interdisciplinary approach, underpinned by scientific first principles and theory to evaluate pollutant sources and sinks, applying biochemodynamic methods, measurements and models Deconstructs prior initiatives in environmental assessment and management using an interdisciplinary approach to evaluate what has worked and why Lays out a holistic understanding of the real impact of human activities on the current state of pollution, linking the physical sciences and engineering with socioeconomic, cultural perspectives, and environmental justice Takes a life cycle view of human and ecological systems, from the molecular to the planetary scale, integrating theories and tools from various disciplines to assess the current and projected states of environmental quality Explains the elements of risk, reliability and resilience of built and natural systems, including discussions of toxicology, sustainability, and human-pollutant interactions based on spatial, biological, and human activity information, i.e. the exposome

Environmental Toxicology

Environmental Toxicology Book
Author : David A. Wright,Pamela Welbourn
Publisher : Cambridge University Press
Release : 2002-03-14
ISBN : 9780521588607
Language : En, Es, Fr & De

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Book Description :

Comprehensive introductory textbook for students and specialists in ecology, environmental science, and chemistry.

Basic Environmental Health

Basic Environmental Health Book
Author : Annalee Yassi
Publisher : Oxford University Press, USA
Release : 2001
ISBN : 019513558X
Language : En, Es, Fr & De

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Book Description :

This comprehensive interdisciplinary text introduces the principles and methods needed to assess and manage environmental health risk. It presents an overview of the scientific basis of environmental health hazards and a basic approach to risk assessment and risk management. The book provides a thorough discussion of routes of exposure and addresses the relationship between environmental health and sustainable development. It also covers ethical issues and action planning.

Toxicology and Risk Assessment

Toxicology and Risk Assessment Book
Author : Helmut Greim,Robert Snyder
Publisher : John Wiley & Sons
Release : 2018-08-10
ISBN : 1119135923
Language : En, Es, Fr & De

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Book Description :

Provides a complete understanding of how our bodies respond to toxicants, and the principles used to assess the health risks of specific exposure scenarios Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition reflects recent advances in science and technology, and provides the scientific background and methodological issues to enable the reader to understand the basic principles in toxicology and to evaluate the health risks of specific exposure scenarios. Completely updated with the latest information, this book offers a concise introduction to the subject. It is divided into five sections: Principles in Toxicology, Organ Toxicology, Methods in Toxicology, Regulatory Toxicology, and Specific Toxicity. The 2nd Edition adds new chapters that cover recent scientific and technological advances and current topics including the endocrine system, alternatives to animal testing, risk assessment and thresholds for carcinogens, European and international regulation, nanomaterials, fuels, fragrances, and agrochemicals. Concentrates on the basic concepts of toxicology and provides sufficient information for the reader to become familiar with them in order to understand the principles and to evaluate the risks at given exposures 30% new chapters cover recent scientific and technological advances including alternatives to animal testing; genotoxic carcinogens; REACH regulations; nanomaterials; fuels; fragrances; PAHs; and agrochemicals Written by a team of international specialists, and edited by two outstanding scientists in the field Fully updated and expanded, Toxicology and Risk Assessment: A Comprehensive Introduction, Second Edition is an essential text for any student or researcher with an interest in toxicology and related risk assessments.

Challenges in Endocrine Disruptor Toxicology and Risk Assessment

Challenges in Endocrine Disruptor Toxicology and Risk Assessment Book
Author : Alberto Mantovani,Alexandra Fucic
Publisher : Royal Society of Chemistry
Release : 2020-12-08
ISBN : 1839160837
Language : En, Es, Fr & De

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Book Description :

Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer’s disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.

Peterson s Annual Guides to Graduate Study

Peterson s Annual Guides to Graduate Study Book
Author : Anonim
Publisher : Unknown
Release : 1983
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Peterson s Annual Guides to Graduate Study book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Particle Toxicology

Particle Toxicology Book
Author : Ken Donaldson,Paul Borm
Publisher : CRC Press
Release : 2006-12-21
ISBN : 1420003143
Language : En, Es, Fr & De

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Book Description :

Exposure to particles in industry and mining and from accidental anthropogenic sources constitutes an ongoing threat. Most recently nanoparticles arising from advances in technology are exposing a wider population to pathogenic stimuli. The effects of inhaled particles are no longer confined to the lung as nanoparticles have the potential to translocate to the bloodstream, the brain, and other target sites. The new questions posed by nanoparticles underscore the importance of interdisciplinary research and exchange and highlight the need for new collaborations among disciplines in medicine, toxicology, chemistry, and material sciences. Particle Toxicology brings together the state of the science in particle physico-chemistry, cell biology, and toxicology in a single volume. While organized around the classical toxicology paradigm of exposure - dose - response, the book is unique in its emphasis on mechanistic toxicology. Preparing the reader with a brief historical overview and a conceptual framework for particle research, the book provides reviews on the mechanisms and properties of pathogenic particles and their effects on target cells at various sites in the body. The text describes how adverse effects are a consequence of deposition, translocation, and the complex issue of “dose” dominates. Contributions from leading researchers address particle-associated pro-inflammatory effects and inflammatory signaling, cellular and extracellular oxidative and nitrosative stress, particulate interactions in the pulmonary, cardiovascular, and central nervous systems, as well as genotoxic effects. Exemplar particles include quartz, asbestos, particulate material and nanoparticles. The book also covers mathematical modeling and human studies as avenues for future research. Responding to the evolving trend of consumer applications for particulate matter, Particle Toxicology provides the comprehensive resource for current knowledge from which to develop new concepts to understanding particle actions, measurement, testing, and pathogenic exposure to fine and ultrafine particles.

Fundamentals of Toxicology

Fundamentals of Toxicology Book
Author : PK Gupta
Publisher : Academic Press
Release : 2016-08-26
ISBN : 0128054034
Language : En, Es, Fr & De

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Book Description :

Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty. Explains the essential concepts of toxicology in a clear fashion Provides in-depth coverage of testing protocols, common drugs, chemicals, and laboratory-based diagnostic and analytical toxicology Explores the history, foundations, and most recent concepts of toxicology Serves as an essential reference for advanced students in toxicology and across the biomedical, life, and environmental sciences who want to learn the concepts of toxicology

Quantitative Environmental Risk Analysis for Human Health

Quantitative Environmental Risk Analysis for Human Health Book
Author : Robert A. Fjeld,Norman A. Eisenberg,Keith L. Compton
Publisher : John Wiley & Sons
Release : 2007-03-22
ISBN : 0470096195
Language : En, Es, Fr & De

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Book Description :

A COMPREHENSIVE TEXTBOOK AND REFERENCE FOR QUANTITATIVE ENVIRONMENTAL RISK ANALYSIS FOR BOTH CHEMICAL AND RADIOACTIVE CONTAMINANTS Environmental risk analysis is complex and interdisciplinary; this book explains the fundamental concepts and analytical methods in each essential discipline. With an emphasis on concepts and applications of quantitative tools plus coverage of analysis of both chemical and radioactive contaminants, this is a comprehensive resource. After an introduction and an overview of the basics of environmental modeling, the book covers key elements in environmental risk analysis methodology, including: Release assessment and source characterization Migration of contaminants in various media, including surface water, groundwater, the atmosphere, and the food chain Exposure assessment Basic human toxicology and dose-response Risk characterization, including dose-response modeling and analysis Risk management process and methods Risk communication and public participation This reference also relates risk analysis to current environmental laws and regulations. An ideal textbook for graduate students and upper-level undergraduates in various engineering and quantitative science disciplines, especially civil and environmental engineering, it is also a great reference for practitioners in industry, environmental consulting firms, and regulatory agencies.

Formaldehyde

Formaldehyde Book
Author : Luoping Zhang
Publisher : Royal Society of Chemistry
Release : 2018-05-24
ISBN : 1782629734
Language : En, Es, Fr & De

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Book Description :

Formaldehyde is virtually ubiquitous in the modern environment due to its cost-effective nature, its use in resin formation, and its preservative properties. Though formaldehyde is necessary for many products and processes important to the world’s economy, this economic dependence on formaldehyde comes at a cost to public health. Growth and consequent industrialization rely heavily on formaldehyde use. New buildings—residences, public places, and offices—are not only built with timber preserved by formaldehyde, but they are also furnished with wood, wool, and textile products that contain formaldehyde. The general population faces environmental exposure from indoor and outdoor air pollution, food, and even medicine. Scientific inquiry into formaldehyde exposure has grown in response. This book consolidates the new and established body of formaldehyde research in the scholarly community, focusing on exposure, genotoxicity, and adverse health outcomes. Through this resource, we hope to increase awareness of the broad range of health effects posed by formaldehyde exposure, and to encourage interdisciplinary interest, as well as research, into this pervasive compound—especially in the United States and China, where formaldehyde production and usage is high. This book will be useful to researchers of environmental and occupational exposure, students, and government regulators and anyone exposed to formaldehyde in the workplace and/or at home.

Biological Monitoring

Biological Monitoring Book
Author : Shane Que Hee
Publisher : John Wiley & Sons
Release : 1993-06-01
ISBN : 9780471290834
Language : En, Es, Fr & De

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Book Description :

This definitive source provides practicing professionals and students in the occupational, environmental, and public health and safety fields with the functional basics of biological monitoring. The author examines how environmental exposures to particular chemicals are related to concentrations of markers in body tissues and fluids. Biological Monitoring integrates the applied sciences of industrial/environmental hygiene, epidemiology, public health, occupational medicine, toxicology, biochemistry, and analytical chemistry with the basic sciences to interpret the connections between exposures and lifestyle/environmental influences, and their effects on humans. This comprehensive introduction provides dependable, detailed coverage of: * monitoring for harmful substances in the workplace * the benefits and limitations of testing for critical levels of toxic materials in bodily tissues and fluids * state-of-the-art developments in biological monitoring * a wide variety of toxic chemicals and selected physical agents * immunoassays * monitoring for HIV and AIDS * importance of exposure routes * the most up-to-date methods of health and medical surveillance * the interpretation of adduct concentrations * biological exposure indices * biological monitoring of pesticides * biological monitoring in the home and around hazardous waste sites * and much more This essential, compelling guide is the only inclusive and thorough introduction available. Biological Monitoring's rigorous, accessible, interdisciplinary approach makes this an invaluable reference and text for industrial and environmental hygienists, physicians, pharmacists, nurses, epidemiologists, toxicologists, laboratory technicians, chemical engineers, science graduate students, and the environmentally concerned.

Environmental Toxicology

Environmental Toxicology Book
Author : Luis M. Botana
Publisher : Walter de Gruyter GmbH & Co KG
Release : 2018-05-22
ISBN : 311043363X
Language : En, Es, Fr & De

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Book Description :

Organic and inorganic chemicals frequently exhibit toxic, mutagenic, carcinogenic, or sensitizing properties when getting in contact with the environment. This comprehensive introduction discusses risk assessment and analysis, environmental fate, transport, and breakdown pathways of chemicals, as well as methods for prevention and procedures for decontamination.

Introduction to Toxicology Third Edition

Introduction to Toxicology  Third Edition Book
Author : John Timbrell
Publisher : CRC Press
Release : 2001-11-15
ISBN : 9780415247634
Language : En, Es, Fr & De

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Book Description :

Since the publication of the first edition of Introduction to Toxicology , toxicology has become a more mature science, the number of undergraduate and postgraduate courses has increased and thus the need for a regularly updated introductory text has become more pressing. This third edition caters for this need in a clear and easy-to-read style, featuring: * Up-to-the-minute information * Relevant toxicological examples that reinforce principles * End-of-chapter essay questions * New and redrawn illustrations * Glossary of terms * Extensively revised bibliography The fundamental principles of absorption, distribution, metabolism and excretion are described in the introductory chapters, as are the types of exposure and response. In subsequent chapters these are clarified with the use of carefully chosen examples. Among the topics considered are the potential adverse effects of drugs, pesticides, food additives and industrial chemicals.

Principles of Toxicology Second Edition

Principles of Toxicology  Second Edition Book
Author : Stine Karen,Thomas M. Brown
Publisher : CRC Press
Release : 2006-01-24
ISBN : 084932856X
Language : En, Es, Fr & De

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Book Description :

Written by two experienced toxicology lecturers, Principles of Toxicology provides a broad-based yet in-depth introduction to this diverse subject. Comprehensive and easy-to-read, the book covers this broad and interdisciplinary field from the viewpoint of three different functional levels: molecular and cellular; physiological; and ecological and environmental. This revised second edition expands the coverage of the book while keeping the organizational format that made the first edition a bestseller. It also includes a series of brief case studies illustrating the application of toxicological principles to current issues of interest. Each and every chapter has been revised, several have been significantly rewritten, and three are entirely new. This new edition retains the extensive cross-referencing system that links all sections and enhances the integration of material. It also includes an appendix of selected toxicants that describes chemical structure and category of use. These features combine to make finding specific information quick and easy. The highly readable format and uniform, consistent presentation of information will make this the most used reference on your shelf. See what's new in the second edition:

Clinical Pharmacology During Pregnancy

Clinical Pharmacology During Pregnancy Book
Author : Donald Mattison
Publisher : Academic Press
Release : 2013
ISBN : 0123860075
Language : En, Es, Fr & De

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Book Description :

Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems, as well as essential content on dosing and efficacy. Written in a clear and practical manner, this reference provides easily accessible information and clinical guidance on how best to treat women with medications during pregnancy. Utilizes an evidence-based approach for therapeutics during pregnancy Includes a summary of specific medications by indication with up-to-date information on dosing and efficacy in pregnancy for the given indication Highlights current research in this area and provides easily accessible and vital information for clinicians Complements the companion volume, Drugs During Pregnancy and Lactation by Schaefer et al and presents a bundling opportunity to the same target audience of medical professionals Includes a companion website containing support materials for professional or continuing education courses in OB pharmacology

Coronavirus Drug Discovery

Coronavirus Drug Discovery Book
Author : Chukwuebuka Egbuna
Publisher : Elsevier
Release : 2022-05-25
ISBN : 0323851789
Language : En, Es, Fr & De

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Book Description :

Coronavirus Drug Discovery: SARS-CoV-2 (Covid 19) Prevention, Diagnosis, and Treatment presents comprehensive information on antiviral drug discovery from medicinal plants, animals, marine organisms and microorganisms. This book present special chapters on the COVID-19 disease outbreak and detailed information on drug discovery for the COVID-19 virus, including its diagnosis and prevention strategies. Subsequent chapters present drug discovery opportunities for the treatment and management of respiratory viral diseases, gastrointestinal viral diseases, exanthematous viral diseases, hepatic viral diseases, cutaneous viral diseases, hemorrhagic viral diseases and neurologic viral diseases. The book's contributors are specialists from key institutions around the world, making this a key resource for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, and toxicologists, among others. Details the various natural bioactive compounds for antiviral drug discoveries surrounding treatments for the coronavirus Discuses recent drug discovery for covid-19 treatment and drug discovery from natural sources Focuses on the discovery of drugs against acute viral diseases of world importance Reviews recent advances in research tools for the discovery of new antiviral drugs