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Age Related Macular Degeneration

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Age Related Macular Degeneration E Book

Age Related Macular Degeneration   E Book Book
Author : Weiye Li
Publisher : Elsevier Health Sciences
Release : 2021-03-23
ISBN : 0128220635
Language : En, Es, Fr & De

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Book Description :

A consolidated view of a complex disorder, Age-Related Macular Degeneration, summarizes the latest evidence-based studies and translates these advancements into practical, actionable knowledge. This concise resource covers the fundamentals of age-related macular degeneration (AMD) diagnosis and treatment along with a modern definition of the disorder that acknowledges the range of presentations that ophthalmologists see in real practice. Offering practical, clinical guidance in addition to capturing new therapeutic approaches in the pipeline, this book is an essential reference for ophthalmologists, optometrists, and researchers. Takes a concise, yet comprehensive, approach to AMD, covering both basic science and clinical guidance. Features clinical guidelines on the diagnosis and treatment of AMD, including classification, signs/symptoms, imaging, and differential diagnosis in the pre-optical coherence tomography (OCT) and modern OCT eras. Presents up-to-date information on AMD therapies currently in the development pipeline and offers insights for the future of translational research. Explains molecular genetics and pathogenic events of AMD from both basic and clinical perspectives, which may help readers seek promising new therapeutic targets Contains more than 250 images, with multimodal imaging techniques that clearly demonstrate AMD pathophysiology and clinical pathology.

Age Related Macular Degeneration

Age Related Macular Degeneration Book
Author : Jay S. Duker,Andre J. Witkin
Publisher : Slack
Release : 2014-09-01
ISBN : 9781617116421
Language : En, Es, Fr & De

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Book Description :

Retinal disease in general, and age-related macular degeneration (AMD) specifically, is of major interest worldwide due to the increasing aging population and the revolution in management of wet AMD over the past several years. Age-Related Macular Degeneration presents an up-to-date, clinically relevant monograph on the current diagnosis and management of AMD. Age-Related Macular Degeneration by Drs. Jay S. Duker and Andre J. Witkin serves as a reference for ophthalmologists treating AMD in the clinic as well as other eye care professionals who see and counsel patients with AMD. Chapters will focus on the pathogenesis and risk factors for AMD, the diagnosis of AMD, treatment options, and promising investigative interventions. To help readers gain familiarity recognizing AMD, the book contains multiple images in different formats: high quality color fundus photographs, black-and-white angiograms, black-and-white autofluorence images, and both color and black-and-white OCT images. Relevant to current management of AMD, Age-Related Macular Degeneration: Current Management concentrates on "clinical utility" rather than emphasizing published studies, filling the current void in the market for the general ophthalmology and optometry audience. Comprehensive ophthalmologists, optometrists and retinal specialists will appreciate the book's practical approach to AMD.

Age related Macular Degeneration

Age related Macular Degeneration Book
Author : G. Robert Hampton,Philip T. Nelsen
Publisher : Raven Press (ID)
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

The epidemiology, pathology, and potential treatments of age-related macular degeneration (AMD) are discussed, along with guidelines for determining the advisability of angiography or referral to specialists. Primarily for general ophthalmologists and ophthalmology students--although chapters on rehabilitation, low vision and the patient's viewpoint are helpful to lay people interested in AMD. Annotation copyright by Book News, Inc., Portland, OR

Age related Macular Degeneration Diagnosis and Treatment

Age related Macular Degeneration Diagnosis and Treatment Book
Author : Allen C. Ho,Carl D. Regillo
Publisher : Springer Science & Business Media
Release : 2011-08-09
ISBN : 9781461401254
Language : En, Es, Fr & De

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Book Description :

Age-Related Macular Degeneration: Diagnosis and Treatment is written by two leading experts from Wills Eye Hospital. Covering the latest therapies and treatments developed in the last few years, this is a concise yet highly illustrated and practical text that guides the clinician through diagnosis and treatment of the leading cause of blindness in older Americans.

Age related Macular Degeneration

Age related Macular Degeneration Book
Author : Anonim
Publisher : Unknown
Release : 1999
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Age related Macular Degeneration book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Age Related Macular Degeneration

Age Related Macular Degeneration Book
Author : Jennifer I. Lim
Publisher : CRC Press
Release : 2007-10-18
ISBN : 9781420019865
Language : En, Es, Fr & De

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Book Description :

Addressing a major condition affecting millions worldwide, this source compiles the most practical and groundbreaking research on the etiology, assessment, and treatment of Age-Related Macular Degeneration (AMD). With full-color illustrations throughout, this reference explores research advancements that have resulted in novel therapies that offer

Age Related Macular Degeneration

Age Related Macular Degeneration Book
Author : W.E. Alberti,G. Richard,R.H. Sagerman
Publisher : Springer Science & Business Media
Release : 2012-12-06
ISBN : 3642564399
Language : En, Es, Fr & De

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Book Description :

Age-related macular degeneration (ARMD) is a frequent disease of the elderly and the most common cause of blindness. Recently, various new treatment options have become available for ARMD. This book, written by recognized experts and including the results of international study groups, provides a comprehensive report on these treatments, documenting their rationale, uses, side-effects, and benefits. It will be of immense value to all with an interest in ARMD.

Age related Macular Degeneration

Age related Macular Degeneration Book
Author : D. Virgil Alfaro
Publisher : Lippincott Williams & Wilkins
Release : 2006
ISBN : 0781738997
Language : En, Es, Fr & De

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Book Description :

A renowned group of retina surgeons presents promising new developments in age-related macular degeneration, with emphasis on the most significant advances in the past five years. Content addresses all aspects of management, including anatomy, physiology, and pathophysiology; imaging of the macula in age-related macular degeneration; prevention measures and treatment; treatment; and future directions. Abundantly illustrated and superbly organized, this book serves as an excellent reference and textbook.

Age Related Macular Degeneration

Age Related Macular Degeneration Book
Author : Melanie Carter
Publisher : Unknown
Release : 2015-01-01
ISBN : 9781634833295
Language : En, Es, Fr & De

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Book Description :

Age-related macular degeneration (AMD) is the leading cause of blindness in individuals older than 65 years of age. The authors of this book discuss the role of genetics, sunlight, diet, cardiovascular factors, smoking and alcohol as possible risk factors for AMD. Furthermore, the dry form is more common and accounts for about 85-90% of AMD patients in the USA, while Japanese AMD patients predominantely progress to wet-form or polypoidal choroidal vasculopathy (PCV). The function of a serine protein gene, HTRA1, in wet-form AMD patients is explored in detail. Conversely, the final chapter evaluates the therapeutic effects of high omega-3 fatty acids as anti-inflammatory agents in dry AMD patients. The preliminary findings indicate a promising therapeutic regime for dry AMD and perhaps for other retinopathies as well.

Age Related Macular Degeneration

Age Related Macular Degeneration Book
Author : Mischayra Torres Rodríguez
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Age-related macular degeneration is a disease that causes blurring of your central vision. The blurring happens because of damage to the macula, a small area at the back of the eye. The macula helps you see the fine detail in things that your eye focusing on. There are two types of macular degeneration: Wet and Dry. The dry form is by far the most common type. The wet form is less common, but it happens more quickly and is more severe. The dry form accounts for about 9 out of 10 cases of macular degeneration. It develops slowly and causes central vision to become dimmer or more blurry over time. It usually does not cause severe vision loss unless it turns into the wet form. The wet form accounts for only about 1 out of 10 cases of macular degeneration. It can cause serious vision loss within months or even weeks. People who have the wet form have the dry form first.

Age related macular degeneration

Age related macular degeneration Book
Author : Frank G. Holz,Daniel Pauleikhoff,Richard F. Spaide,Alan C. Bird
Publisher : Springer Science & Business Media
Release : 2013-03-09
ISBN : 3662051990
Language : En, Es, Fr & De

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Book Description :

Age-related macular degeneration has become the most common cause of blindness. With population ageing AMD will become an ever more prevalent cause of visual loss unless more effective modes of treatment will be found. Here, an expert panel of experienced clinicians and eminent basic scientists provide for an authoritative review on the pathogenesis, epidemiology and risk factors, diagnostic methods and imaging modalities for age-related macular degeneration. Many photographs and diagrams add to a clear understanding.

Age related Macular Degeneration and the Role of the Complement System

Age related Macular Degeneration and the Role of the Complement System Book
Author : Anonim
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Highlights: The alternative complement pathway plays a major role in AMD pathogenesis. Variants in genes including CFH, CFHRs, CFI, CFB and C3 modify AMD risk. MAC accumulates in the choriocapillaris and Bruch's membrane during ageing. The truncated version of FH, FHL-1 protects Bruch's membrane from complement activation. Abstract: Age-related macular degeneration (AMD) is a leading cause of visual impairment. It is characterised by damage to a tissue complex composed of the retinal pigment epithelium, Bruch's membrane and choriocapillaris. In early AMD extracellular debris including drusen accumulates in Bruch's membrane and then in late AMD geographic atrophy and/or neovascularisation develop. Variants in genes encoding components of the alternative pathway of the complement cascade have a major influence on AMD risk, especially at the RCA locus on chromosome 1, which contains CFH and the CFHR genes. Immunohistochemical studies have demonstrated complement components in unaffected and AMD macular tissue. Whilst other factors, including oxidative stress, play important roles in AMD pathogenesis, evidence for the central role played by complement dysregulation is discussed in this review.

The First Year Age Related Macular Degeneration

The First Year  Age Related Macular Degeneration Book
Author : Daniel L. Roberts
Publisher : Da Capo Lifelong Books
Release : 2006-08-29
ISBN : 9781569242865
Language : En, Es, Fr & De

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Book Description :

Age-related macular degeneration (AMD) is a progressive disease of the retina that develops when the light-sensing cells in the central area of vision (the macula) stop working and eventually die. Thought to be caused by a combination of genetic and environmental factors, the disease is the leading cause of blindness in people over 50. In 1995, Dan Roberts retired from teaching to help others who also suffered from macular degeneration. Roberts has established support networks for AMD patients and provided free presentations about vision impairment at schools, community organizations, and support groups across the country. The First Year: Age-Related Macular Degeneration is an essential resource for those who want to be an informed, active participant in the management of their condition.

Combined Therapies to Treat CNV in AMD PDT Anti VEGF

Combined Therapies to Treat CNV in AMD  PDT   Anti VEGF  Book
Author : Jorge Mataix,Amparo Navea,Elena Palacios,M. Carmen Desco
Publisher : Unknown
Release : 2012
ISBN : 9789533078649
Language : En, Es, Fr & De

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Book Description :

Download Combined Therapies to Treat CNV in AMD PDT Anti VEGF book written by Jorge Mataix,Amparo Navea,Elena Palacios,M. Carmen Desco, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Non age Related Macular Degeneration

Non age Related Macular Degeneration Book
Author : Enzo B. Mercier
Publisher : Nova Biomedical Books
Release : 2008-01-01
ISBN : 9781604563054
Language : En, Es, Fr & De

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Book Description :

Macular degeneration is diagnosed as either dry (non-neovascular) or wet (neovascular). Neovascular refers to growth of new blood vessels in an area, such as the macula, where they are not supposed to be. The dry form is more common than the wet, with about 85%-90% patients diagnosed. The wet form of the disease usually leads to more serious vision loss. Different forms of macular degeneration may occur in younger patients. These non-age related cases may be linked to heredity, diabetes, nutritional deficits, head injury, infection, or other factors. This new book presents the latest research from around the world.

Essential Hypertension in the Pathogenesis of Age related Macular Degeneration

Essential Hypertension in the Pathogenesis of Age related Macular Degeneration Book
Author : Anonim
Publisher : Unknown
Release : 2015
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Abstract : Age-related macular degeneration (AMD) is one of the main causes of vision loss, especially in the elderly. The involvement of essential hypertension in its pathogenesis has been well covered in the literature since it was first recognized. Hemodynamic abnormalities appear to contribute to AMD, with the renin–angiotensin system playing a significant role. Many studies have demonstrated that high blood pressure is associated with lower choroidal blood flow and disturbed vascular homeostasis in these patients. In addition, AMD is characterized by abnormal neovascularization, to which angiotensin II and growth factors make a large contribution. Most epidemiological studies have found essential hypertension to be a risk factor for AMD. However, although all agree that the strongest predisposing factors are age and smoking, overall there is some inconsistency regarding the exact role of hypertension in its pathogenesis. In particular, there are no data in the literature to support the view that antihypertensive medication and the successful management of hypertension have a positive effect on the clinical outcome of AMD. This reinforces the data indicating that the cause of AMD is multifactorial and suggests that, although essential hypertension probably plays a role, in itself it is unlikely to be a major contributor to the future occurrence of AMD.

An Investigation Into the Inflammatory Axis of Age Related Macular Degeneration

An Investigation Into the Inflammatory Axis of Age Related Macular Degeneration Book
Author : D. P. Gates
Publisher : Unknown
Release : 2008
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download An Investigation Into the Inflammatory Axis of Age Related Macular Degeneration book written by D. P. Gates, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

BIOMARKERS OF NEOVASCULAR ACTIVITY IN AGE RELATED MACULAR DEGENERATION USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

BIOMARKERS OF NEOVASCULAR ACTIVITY IN AGE RELATED MACULAR DEGENERATION USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY  Book
Author : Anonim
Publisher : Unknown
Release : 2018
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Abstract : Purpose: To study the qualitative and quantitative features of choroidal neovascular (NV) membranes in age-related macular degeneration using optical coherence tomography angiography in patients with active and quiescent NV lesions before and after treatment with anti–vascular endothelial growth factor. Methods: Macular optical coherence tomography angiography images were obtained using RTVue XR Avanti with AngioVue. Morphologic features and quantitative measurements of the NV lesion were analyzed using en face projection images. The NV lesion was subdivided into inner segment and outer fringe for further fractal dimension analysis. Results: In a series of 31 eyes, 11 eyes with active NV lesions at baseline and after consecutive follow-up after treatment with anti–vascular endothelial growth factor therapy and 20 eyes with quiescent NV lesions were included in this study. Morphologically, all the quiescent NV lesions versus 63.6% of the active NV lesions demonstrated a prominent central vessel and active leasions demonstrated a greater rate of small vessels branching (82%) and peripheral arcades (82%) than quiescent lesions (30% and 40% respectively) and this was statistically significant. The lesion area and vessel density was not statistically significantly different after treatment or versus quiescent lesions although the latter lesions were reduced in area. Lesion pattern complexity measured by the fractal dimension was statistically significantly lower in the inner part of the lesion after treatment and statistically significantly lower in the total lesion of the quiescent NV compared with the active NV. Conclusion: Optical coherence tomography angiography is a new, noninvasive imaging modality that can be used to perform qualitative and quantitative analyses of NV lesions. In the future, OCT angiography may provide biomarkers of activity and guide the evaluation and treatment and monitoring of neovascularization in age-related macular degeneration. Abstract : The authors evaluated the structural features of active neovascularization before and after treatment versus inactive or quiescent neovascularization secondary to age-related macular degeneration using qualitative and quantitative OCT angiography. Active lesions showed similar morphologic and quantitative features before and after treatment but quiescent lesions differed qualitatively and quantitatively compared with active neovascularization.

Age Related Macular Degeneration

Age Related Macular Degeneration Book
Author : Weiye Li
Publisher : Elsevier
Release : 2021-03
ISBN : 9780128220610
Language : En, Es, Fr & De

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Book Description :

Authoritative and research-based, Age-Related Macular Degeneration summarizes the latest evidence-based research on this complex disorder and translates these advancements into practical, actionable knowledge. This concise resource covers the fundamentals of age-related macular degeneration (AMD) diagnosis and treatment along with a modern definition of the disorder that acknowledges the range of presentations that ophthalmologists see in patients. Offering useful clinical guidance in addition to capturing new therapeutic approaches in the pipeline, this book is an essential reference for ophthalmologists, optometrists, and researchers. Focuses on practical application of the latest evidence-based research, summarizing current clinical trials and translating advancements into clinical practice. Provides a well-rounded view of the diagnosis of age-related macular degeneration at various stages through a work-up of key differential diagnoses for both wet and dry AMD. Summarizes the genetics of AMD and how genetics can impact response to therapy. Includes an overview of key imaging modalities, such as fundus autofluorescence (FAF), fluorescein angiography (FA), indocyanine green angiography (ICG), optical coherence tomography (OCT), and OCT-angiography (OCTA). Covers current therapeutic approaches as well as those on the horizon, including anti-VEGF therapy, Brolucizumab and Abicipar pegol, immunotherapy, and complement modulators.

Age related Macular Degeneration

Age related Macular Degeneration Book
Author : Emily Chew,Anand Swaroop
Publisher : Springer
Release : 2021-05-24
ISBN : 9783030660130
Language : En, Es, Fr & De

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Book Description :

This edited book focuses on the recent advances in our understanding of age-related macular degeneration (AMD), combining epidemiology and clinical diagnosis, with genetics and immunological aspects as well as the role of proteostasis and mitochondria before diving into new therapies including stem cell based approaches. AMD is a leading cause of largely incurable blindness worldwide and projected to double from 2.07 million to 5.44 million individuals by 2050 in the United States. Globally, 288 million individuals are projected to have AMD by 2040. The disease has enormous socioeconomic impact on the affected individuals, their families and the society. This book will bring together the state of the art basic science knowledge with clinically relevant findings and address the challenges for future research in AMD. The intersection of different disciplines will provide potential areas for further investigations to reduce the burden of blindness from AMD. This book offers an appealing and insightful resource for clinicians, scientists, students and fellows.