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Advances In Chemical Proteomics

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Advances in Chemical Proteomics

Advances in Chemical Proteomics Book
Author : Xudong Yao
Publisher : Elsevier
Release : 2021-04-15
ISBN : 9780128214336
Language : En, Es, Fr & De

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Book Description :

Advances in Chemical Proteomics provides essential concepts and recent applications in the field of chemical proteomics, including chemical probes and tool compounds. The book begins with a section on probes, tool compounds and concepts for chemical proteomics, then moves on to cover applications including solid-phase reagents, fragment screening, designer compounds and protein lipidation. The second volume in the Developments in Organic Chemistry series, each chapter is written by an expert practitioner in the field. This book is a valuable reference for organic chemists and chemical biologists who are interested in developing tool compounds and reagents to measure and interrogate the proteome, develop drug leads and measure off-target effects and drug toxicity, as well as analytical chemists who are interested in better understanding organic chemistry behind commonly used reagents for quantitative proteomics and tools compounds in the emerging field of chemical proteomics. An ideal introductory book to chemical proteomics for organic chemists, pharmaceutical chemists, and chemical biologists Includes advanced, recent applications and reviews in chemical proteomics Written by a global team of experts practicing in the field of proteomics

Mass Spectrometry Based Chemical Proteomics

Mass Spectrometry Based Chemical Proteomics Book
Author : W. Andy Tao,Ying Zhang
Publisher : John Wiley & Sons
Release : 2019-09-04
ISBN : 1118969553
Language : En, Es, Fr & De

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Book Description :

Emphasizing mass spectrometry, this book provides strategies and concepts for understanding and analyzing chemical proteomics, their functions, modifications, and interactions. Chapters cover technical advances and applications in drug discovery, from target identification to validation and potential treatments. Provides a basic overview of chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including proteome profiling and chemical probes Explains technical advances in the field and describes on shotgun proteomics, protein profiling, quantitative proteomics, peptide biosensors, and glycoprotein analysis Includes a wide variety of applications in drug discovery, from drug targets to the chemoproteomics analysis of natural products

Mass Spectrometry Based Chemical Proteomics

Mass Spectrometry Based Chemical Proteomics Book
Author : W. Andy Tao,Ying Zhang
Publisher : John Wiley & Sons
Release : 2019-07-10
ISBN : 1118970217
Language : En, Es, Fr & De

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Book Description :

PROVIDES STRATEGIES AND CONCEPTS FOR UNDERSTANDING CHEMICAL PROTEOMICS, AND ANALYZING PROTEIN FUNCTIONS, MODIFICATIONS, AND INTERACTIONS—EMPHASIZING MASS SPECTROMETRY THROUGHOUT Covering mass spectrometry for chemical proteomics, this book helps readers understand analytical strategies behind protein functions, their modifications and interactions, and applications in drug discovery. It provides a basic overview and presents concepts in chemical proteomics through three angles: Strategies, Technical Advances, and Applications. Chapters cover those many technical advances and applications in drug discovery, from target identification to validation and potential treatments. The first section of Mass Spectrometry-Based Chemical Proteomics starts by reviewing basic methods and recent advances in mass spectrometry for proteomics, including shotgun proteomics, quantitative proteomics, and data analyses. The next section covers a variety of techniques and strategies coupling chemical probes to MS-based proteomics to provide functional insights into the proteome. In the last section, it focuses on using chemical strategies to study protein post-translational modifications and high-order structures. Summarizes chemical proteomics, up-to-date concepts, analysis, and target validation Covers fundamentals and strategies, including the profiling of enzyme activities and protein-drug interactions Explains technical advances in the field and describes on shotgun proteomics, quantitative proteomics, and corresponding methods of software and database usage for proteomics Includes a wide variety of applications in drug discovery, from kinase inhibitors and intracellular drug targets to the chemoproteomics analysis of natural products Addresses an important tool in small molecule drug discovery, appealing to both academia and the pharmaceutical industry Mass Spectrometry-Based Chemical Proteomics is an excellent source of information for readers in both academia and industry in a variety of fields, including pharmaceutical sciences, drug discovery, molecular biology, bioinformatics, and analytical sciences.

Advances in Clinical Chemistry and Laboratory Medicine

Advances in Clinical Chemistry and Laboratory Medicine Book
Author : Harald Renz,Rudolf Tauber
Publisher : Walter de Gruyter
Release : 2012-10-01
ISBN : 311022464X
Language : En, Es, Fr & De

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Book Description :

This volume comprises the invited plenary lectures and contributed papers presented at the WorldMedLab and the EuroMedLab in Berlin, May 2011 with more than 5.000 participants. The contributions in this volume provide a valuable and wide-ranging overview of current research in Laboratory Medicine and cognate disciplines. Special focus is given to Aging Society (neurological diseases), Tumors, Organ specific dysfunctions and Future of Laboratory Medicine.

Advances in Protein Chemistry and Structural Biology

Advances in Protein Chemistry and Structural Biology Book
Author : David S. Eisenberg,Alexander McPherson
Publisher : Academic Press
Release : 2009
ISBN : 9780123748270
Language : En, Es, Fr & De

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Book Description :

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This eclectic volume features articles on a variety of topical subjects. . Includes new information about protocols and analysis of proteins . Eclectic volume presents chapters by a wide range of leading experts . Presents new, cutting-edge information that will serve as an essential addition to any bookshelf or laboratory

Phorbols Advances in Research and Application 2012 Edition

Phorbols   Advances in Research and Application  2012 Edition Book
Author : Anonim
Publisher : ScholarlyEditions
Release : 2012-12-26
ISBN : 1481624660
Language : En, Es, Fr & De

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Book Description :

Phorbols—Advances in Research and Application: 2012 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Phorbols in a compact format. The editors have built Phorbols—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Phorbols in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Phorbols—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Genomics and Proteomics

Advances in Genomics and Proteomics Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Advances in Genomics and Proteomics book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Proteomics in Biomedicine and Pharmacology

Proteomics in Biomedicine and Pharmacology Book
Author : Rossen Donev
Publisher : Academic Press
Release : 2014-06-24
ISBN : 9780128004531
Language : En, Es, Fr & De

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Book Description :

Volume 95 of Advances in Protein Chemistry and Structural Biology focuses on advances in proteomic techniques and their application in biomedicine and pharmacology. This volume describes in detail the applications of these techniques in studying a number of diseases and specific protein modifications and profiles, including phosphoproteomics, glycoproteomics, and more. Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology series is the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins. Each thematically organized volume is guest edited by leading experts in a broad range of protein-related topics. Describes advances in application of powerful techniques in translational research (biomedicine and pharmacology) Chapters are written by authorities in their field Targeted to a wide audience of researchers, specialists, and students The information provided in the volume is well supported by a number of high quality illustrations, figures, and tables

Proteome Characterization and Proteomics

Proteome Characterization and Proteomics Book
Author : Timothy D. Veenstra,Richard D. Smith
Publisher : Academic Press
Release : 2003-09-04
ISBN : 9780120342655
Language : En, Es, Fr & De

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Book Description :

The content of this volume is designed to reach a wide audience, including those involved with relevant technologies such as electrophoresis and mass spectrometry, to those interested in how proteomics can benefit research. A wide range of techniques are discussed, each specifically designed to address different needs in proteomic analysis. The concluding chapter discusses the important issue related to handling large amounts of data accumulated in proteomic studies. Discusses proteomics in the postgenomic age Includes various strategies for quantitative proteomics Covers the role of MS in structural functional proteomics and proteomics in drug discovery and bioinformatics

Advances in Mathematical Chemistry and Applications

Advances in Mathematical Chemistry and Applications  Book
Author : Subhash C. Basak,Guillermo Restrepo,Jose L. Villaveces
Publisher : Elsevier
Release : 2016-02-11
ISBN : 1681081970
Language : En, Es, Fr & De

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Book Description :

Advances in Mathematical Chemistry and Applications highlights the recent progress in the emerging discipline of discrete mathematical chemistry. Editors Subhash C. Basak, Guillermo Restrepo, and Jose Luis Villaveces have brought together 27 chapters written by 68 internationally renowned experts in these two volumes. Each volume comprises a wise integration of mathematical and chemical concepts and covers numerous applications in the field of drug discovery, bioinformatics, chemoinformatics, computational biology, mathematical proteomics, and ecotoxicology. Volume 1 includes chapters on mathematical structural descriptors of molecules and biomolecules, applications of partially ordered sets (posets) in chemistry, optimal characterization of molecular complexity using graph theory, different connectivity matrices and their polynomials, use of 2D fingerprints in similarity-based virtual screening, mathematical approaches to molecular structure generation, comparability graphs, applications of molecular topology in drug design, density functional theory of chemical reactivity, application of mathematical descriptors in the quantification of drug-likeness, utility of pharmacophores in drug design, and much more. Brings together both the theoretical and practical aspects of the fundamental concepts of mathematical chemistry Covers applications in diverse areas of physics, chemistry, drug discovery, predictive toxicology, systems biology, chemoinformatics, and bioinformatics Revised 2015 edition includes a new chapter on the current landscape of hierarchical QSAR modelling About half of the book focuses primarily on current work, new applications, and emerging approaches for the mathematical characterization of essential aspects of molecular structure, while the other half describes applications of structural approach to new drug discovery, virtual screening, protein folding, predictive toxicology, DNA structure, and systems biology

Recent Advances in Proteomics Research

Recent Advances in Proteomics Research Book
Author : Sameh Magdeldin
Publisher : BoD – Books on Demand
Release : 2015-11-11
ISBN : 9535122010
Language : En, Es, Fr & De

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Book Description :

Proteomics refers to the entire complement of proteins, including modification. This promising discipline has enabled us to study proteins from a massive and comprehensive point of view. The book Recent Advances in Proteomics Research describes in five sections some of the applications of proteomics. This fine research has been written by leading experts worldwide. This book is aimed mainly at those interested in proteins and in the field of proteins, particularly biochemists, biologists, pharmacists, advanced graduate students and postgraduate researchers.

Chemical Reagents for Protein Modification Fourth Edition

Chemical Reagents for Protein Modification  Fourth Edition Book
Author : Roger L. Lundblad
Publisher : Unknown
Release : 2014-01-01
ISBN : 9781306889926
Language : En, Es, Fr & De

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Book Description :

The use of the chemical modification of proteins has evolved over the past 80 years, benefiting from advances in analytical, physical, and organic chemistry. Over the past 30 years, the use of chemical reagents to modify proteins has been crucial in determining the function and structure of purified proteins. This groundbreaking work is part of the foundation of emerging disciplines of proteomics, chemical biology, structure biology, and chemical proteomics. Chemical Reagents for Protein Modification, Fourth Edition provides a comprehensive review of reagents used for the chemical modification of proteins, representing a major revision of the work presented in previous editions. The completely updated Fourth Edition is substantially larger and includes five new chapters: Alkylating Agents Acylating Agents Nitration and Nitrosylation Oxidation Modification of Proteins with Reducing Agents There is greatly increased coverage of the chemical modification of cysteine, which is critical for bioconjugate synthesis. The chapter on reduction also provides information necessary for bioconjugate synthesis as well as for the processing of inclusion bodies. The book places emphasis on conditions that affect the specificity of the chemical modification of proteins, such as solvent and temperature. The format has been markedly revised, presenting information based on the chemical nature of the modifying material and on the amino acid residue modified. This new version has increased significance to biopharmaceuticals. Much of the information is in tabular form, which enables the rapid location of cited material.

Computational Chemistry Methods in Structural Biology

Computational Chemistry Methods in Structural Biology Book
Author : Christo Christov
Publisher : Academic Press
Release : 2011
ISBN : 0123864852
Language : En, Es, Fr & De

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Book Description :

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. This volume features articles on Computational Chemistry methods in Structural Biology. Essential resource for protein chemists This volume features articles on Computational Chemistry methods in Structural Biology

Inflammation in Neuropsychiatric Disorders

Inflammation in Neuropsychiatric Disorders Book
Author : Anonim
Publisher : Academic Press
Release : 2012-08-16
ISBN : 9780123983145
Language : En, Es, Fr & De

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Book Description :

Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. Covers reviews of methodology and research in all aspects of protein chemistry Brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics

Advances in Computational Toxicology

Advances in Computational Toxicology Book
Author : Huixiao Hong
Publisher : Springer
Release : 2019-05-21
ISBN : 3030164438
Language : En, Es, Fr & De

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Book Description :

This book provides a comprehensive review of both traditional and cutting-edge methodologies that are currently used in computational toxicology and specifically features its application in regulatory decision making. The authors from various government agencies such as FDA, NCATS and NIEHS industry, and academic institutes share their real-world experience and discuss most current practices in computational toxicology and potential applications in regulatory science. Among the topics covered are molecular modeling and molecular dynamics simulations, machine learning methods for toxicity analysis, network-based approaches for the assessment of drug toxicity and toxicogenomic analyses. Offering a valuable reference guide to computational toxicology and potential applications in regulatory science, this book will appeal to chemists, toxicologists, drug discovery and development researchers as well as to regulatory scientists, government reviewers and graduate students interested in this field.

Advances in Mass Spectrometry

Advances in Mass Spectrometry Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Advances in Mass Spectrometry book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Advances in Potato Chemistry and Technology

Advances in Potato Chemistry and Technology Book
Author : Jaspreet Singh,Lovedeep Kaur
Publisher : Academic Press
Release : 2016-01-19
ISBN : 0128005769
Language : En, Es, Fr & De

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Book Description :

Advances in Potato Chemistry and Technology, Second Edition, presents the latest knowledge on potato chemistry, including the identification, analysis, and uses of chemical components in potatoes. Beginning with a brief description of potato components, the book then delves into their role during processing, then presenting information on strategies for quality optimization that provides students, researchers, and technologists working in the area of food science with recent information and updates on state-of-the-art technologies. The updated edition includes the latest information related to the identification, analysis, and use of chemical components of potatoes, carbohydrate and non-carbohydrate composition, cell wall chemistry, an analysis of glycoalkaloids, phenolics and anthocyanins, thermal processing, and quality optimization. In addition, new and sophisticated methods of quality determination of potatoes and their products, innovative and healthy potato-based foods, the future of genetically modified potatoes, and the non-food use of potatoes and their products is discussed. Includes both the emerging non-food uses of potato and potato-by-products as well as the expanding knowledge on the food-focused use of potatoes Presents case studies on the problems, factors, proposed solutions, and pros and cons of each, allowing readers facing similar concerns and issues to effectively and efficiently identify an appropriate solution Written by a global collection of experts in both food and non-food potato science

Chemical Engineering Progress

Chemical Engineering Progress Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Chemical Engineering Progress book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Chemical Reagents for Protein Modification

Chemical Reagents for Protein Modification Book
Author : ROGER L. LUNDBLAD
Publisher : CRC Press
Release : 2021-03-30
ISBN : 9780367659165
Language : En, Es, Fr & De

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Book Description :

The use of the chemical modification of proteins has evolved over the past 80 years, benefiting from advances in analytical, physical, and organic chemistry. Over the past 30 years, the use of chemical reagents to modify proteins has been crucial in determining the function and structure of purified proteins. This groundbreaking work is part of the foundation of emerging disciplines of proteomics, chemical biology, structure biology, and chemical proteomics. Chemical Reagents for Protein Modification, Fourth Edition provides a comprehensive review of reagents used for the chemical modification of proteins, representing a major revision of the work presented in previous editions. The completely updated Fourth Edition is substantially larger and includes five new chapters: Alkylating Agents Acylating Agents Nitration and Nitrosylation Oxidation Modification of Proteins with Reducing Agents There is greatly increased coverage of the chemical modification of cysteine, which is critical for bioconjugate synthesis. The chapter on reduction also provides information necessary for bioconjugate synthesis as well as for the processing of inclusion bodies. The book places emphasis on conditions that affect the specificity of the chemical modification of proteins, such as solvent and temperature. The format has been markedly revised, presenting information based on the chemical nature of the modifying material and on the amino acid residue modified. This new version has increased significance to biopharmaceuticals. Much of the information is in tabular form, which enables the rapid location of cited material.

Philosophical Transactions

Philosophical Transactions Book
Author : Anonim
Publisher : Unknown
Release : 2021-06-17
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Philosophical Transactions book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.