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Addictive Substances And Neurological Disease

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Addictive Substances and Neurological Disease

Addictive Substances and Neurological Disease Book
Author : Ronald Ross Watson,Sherma Zibadi
Publisher : Academic Press
Release : 2017-02-18
ISBN : 0128092963
Language : En, Es, Fr & De

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Book Description :

Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. Integrates current research on the actions of addictive substances in neurological disease Includes functional foods, such as caffeine beverages, that have habituating effects on the brain Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances

Drugs Brains and Behavior

Drugs  Brains  and Behavior Book
Author : Anonim
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

"Drugs, Brains, and Behavior" is an online textbook written by C. Robin Timmons and Leonard W. Hamilton. The book was previously published by Prentice Hall, Inc. in 1990 as "Principles of Behavioral Pharmacology." The authors attempt to develop an understanding of the interpenetration of brain, behavior and environment. They discuss the chemistry of behavior in both the literal sense of neurochemistry and the figurative sense of an analysis of the reactions with the environment.

Evaluating the Brain Disease Model of Addiction

Evaluating the Brain Disease Model of Addiction Book
Author : Nick Heather,Matt Field,Antony C. Moss,Sally Satel
Publisher : Routledge
Release : 2022-03-07
ISBN : 1000540065
Language : En, Es, Fr & De

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Book Description :

This ground-breaking book advances the fundamental debate about the nature of addiction. As well as presenting the case for seeing addiction as a brain disease, it brings together all the most cogent and penetrating critiques of the brain disease model of addiction (BDMA) and the main grounds for being skeptical of BDMA claims. The idea that addiction is a brain disease dominates thinking and practice worldwide. However, the editors of this book argue that our understanding of addiction is undergoing a revolutionary change, from being considered a brain disease to a disorder of voluntary behavior. The resolution of this controversy will determine the future of scientific progress in understanding addiction, together with necessary advances in treatment, prevention, and societal responses to addictive disorders. This volume brings together the various strands of the contemporary debate about whether or not addiction is best regarded as a brain disease. Contributors offer arguments for and against, and reasons for uncertainty; they also propose novel alternatives to both brain disease and moral models of addiction. In addition to reprints of classic articles from the addiction research literature, each section contains original chapters written by authorities on their chosen topic. The editors have assembled a stellar cast of chapter authors from a wide range of disciplines – neuroscience, philosophy, psychiatry, psychology, cognitive science, sociology, and law – including some of the most brilliant and influential voices in the field of addiction studies today. The result is a landmark volume in the study of addiction which will be essential reading for advanced students and researchers in addiction as well as professionals such as medical practitioners, psychiatrists, psychologists of all varieties, and social workers.

The Biology of Desire

The Biology of Desire Book
Author : Marc Lewis
Publisher : Doubleday Canada
Release : 2015-08-04
ISBN : 0385682298
Language : En, Es, Fr & De

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Book Description :

Through the vivid, true stories of five people who journeyed into and out of addiction, a renowned neuroscientist explains why the “disease model” of addiction is wrong and illuminates the path to recovery. The psychiatric establishment and rehab industry in the Western world have branded addiction a brain disease, based on evidence that brains change with drug use. But in The Biology of Desire, cognitive neuroscientist and former addict Marc Lewis makes a convincing case that addiction is not a disease, and shows why the disease model has become an obstacle to healing. Lewis reveals addiction as an unintended consequence of the brain doing what it’s supposed to do—seek pleasure and relief—in a world that’s not cooperating. Brains are designed to restructure themselves with normal learning and development, but this process is accelerated in addiction when highly attractive rewards are pursued repeatedly. Lewis shows why treatment based on the disease model so often fails, and how treatment can be retooled to achieve lasting recovery, given the realities of brain plasticity. Combining intimate human stories with clearly rendered scientific explanation, The Biology of Desire is enlightening and optimistic reading for anyone who has wrestled with addiction either personally or professionally.

The Addicted Brain

The Addicted Brain Book
Author : Michael J. Kuhar
Publisher : FT Press
Release : 2012
ISBN : 0132542501
Language : En, Es, Fr & De

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Book Description :

A scientific explanation of addiction by a leading neuroscientist looks at how and why people become addicts and discusses advances in prevention and treatment.

Surviving Addictive Substances Replacing Shame with Science

Surviving Addictive Substances  Replacing Shame with Science Book
Author : Bourne
Publisher : Unknown
Release : 2021-12
ISBN : 9780578969787
Language : En, Es, Fr & De

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Book Description :

The science about dopamine and the survival center of the brain shows that anyone with a brain can get a substance use disorder. Therefore, this is nobody's fault. The science also suggests why treatment requires staying away from drugs and alcohol, keeping safe from people, places, and things that trigger drug use, and getting support with past and present needs. In this book, Dr. Margaret Bourne shares her understanding of the science of addiction in an effort to give hope to people suffering from substance use disorders and to their friends and families, including: Shame and blame are our greatest barriers to recovery from substance use disorders. The words we use when talking about substance use disorders make a difference. Substance use disorders are chronic brain diseases that require lifelong daily treatment. Addictive substances take over a part of our brain that is supposed to help us survive, making us behave in ways that do the exact opposite. Substance use disorders are diseases of the brain and make people act differently from who they really are. Because substance use disorders are brain diseases, the treatment requires following directions given by people who understand the disease as the brain heals, rather than trying to solve your problems alone. Successful treatment of substance use disorders is not a matter of how bad the disease is but rather how willing you are to follow the directions of your treatment team. Substance use disorders can be treated just like any medical illness.

Addiction

Addiction Book
Author : Gene M. Heyman
Publisher : Harvard University Press
Release : 2009-10-15
ISBN : 0674053990
Language : En, Es, Fr & De

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Book Description :

In a book sure to inspire controversy, Gene Heyman argues that conventional wisdom about addiction - that it is a disease, a compulsion beyond conscious control - is wrong. At the heart of Heyman's analysis is a startling view of choice and motivation that applies to all choices, not just the choice to use drugs. Heyman’s analysis of well-established but frequently ignored research leads to unexpected insights into how we make choices - from obesity to McMansionization - all rooted in our deep-seated tendency to consume too much of whatever we like best.

Unbroken Brain

Unbroken Brain Book
Author : Maia Szalavitz
Publisher : St. Martin's Press
Release : 2016-04-05
ISBN : 1466859563
Language : En, Es, Fr & De

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Book Description :

A NEW YORK TIMES BESTSELLER More people than ever before see themselves as addicted to, or recovering from, addiction, whether it be alcohol or drugs, prescription meds, sex, gambling, porn, or the internet. But despite the unprecedented attention, our understanding of addiction is trapped in unfounded 20th century ideas, addiction as a crime or as brain disease, and in equally outdated treatment. Challenging both the idea of the addict's "broken brain" and the notion of a simple "addictive personality," The New York Times Bestseller, Unbroken Brain, offers a radical and groundbreaking new perspective, arguing that addictions are learning disorders and shows how seeing the condition this way can untangle our current debates over treatment, prevention and policy. Like autistic traits, addictive behaviors fall on a spectrum -- and they can be a normal response to an extreme situation. By illustrating what addiction is, and is not, the book illustrates how timing, history, family, peers, culture and chemicals come together to create both illness and recovery- and why there is no "addictive personality" or single treatment that works for all. Combining Maia Szalavitz's personal story with a distillation of more than 25 years of science and research,Unbroken Brain provides a paradigm-shifting approach to thinking about addiction. Her writings on radical addiction therapies have been featured in The Washington Post, Vice Magazine, The Wall Street Journal, and The New York Times, in addition to multiple other publications. She has been interviewed about her book on many radio shows including Fresh Air with Terry Gross and The Brian Lehrer show.

Drugs and the Future

Drugs and the Future Book
Author : David J. Nutt,Trevor W. Robbins,Gerald V. Stimson,Martin Ince,Andrew Jackson
Publisher : Elsevier
Release : 2006-12-11
ISBN : 9780080467740
Language : En, Es, Fr & De

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Book Description :

Drugs and the Future presents 13 reviews collected to present the new advances in all areas of addiction research, including knowledge gained from mapping the human genome, the improved understanding of brain pathways and functions that are stimulated by addictive drugs, experimental and clinical psychology approaches to addiction and treatment, as well as both ethical considerations and social policy. The book also includes chapters on the history of addictive substances and some personal narratives of addiction. Introduced by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and Nora Volkow, director of the National Institute on Drug Abuse in the USA, the book uniquely covers the full range of disciplines which can provide insight into the future of addiction, from genetics to the humanities. Written for a scientific audience, it is also applicable to non-specialists as well. Provides an unique overview of what we know about addiction, and how scientific knowledge can and should be applied in the societal, ethical, and political context Applies the state-of-the-art research in fields such as Genomics, Neuroscience, Pharmacology, Social Policy and Ethics to addiction research Includes a preface by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and in introduction by Nora Volkow, director of the National Institute on Drug Abuse in the USA

Memoirs of an Addicted Brain

Memoirs of an Addicted Brain Book
Author : Marc Lewis
Publisher : Doubleday Canada
Release : 2011-10-04
ISBN : 0385669267
Language : En, Es, Fr & De

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Book Description :

A gripping, ultimately triumphant memoir that's also the most comprehensive and comprehensible study of the neuroscience of addiction written for the general public. FROM THE INTRODUCTION: "We are prone to a cycle of craving what we don't have, finding it, using it up or losing it, and then craving it all the more. This cycle is at the root of all addictions, addictions to drugs, sex, love, cigarettes, soap operas, wealth, and wisdom itself. But why should this be so? Why are we desperate for what we don't have, or can't have, often at great cost to what we do have, thereby risking our peace and contentment, our safety, and even our lives?" The answer, says Dr. Marc Lewis, lies in the structure and function of the human brain. Marc Lewis is a distinguished neuroscientist. And, for many years, he was a drug addict himself, dependent on a series of dangerous substances, from LSD to heroin. His narrative moves back and forth between the often dark, compellingly recounted story of his relationship with drugs and a revelatory analysis of what was going on in his brain. He shows how drugs speak to the brain - which is designed to seek rewards and soothe pain - in its own language. He shows in detail the neural mechanics of a variety of powerful drugs and of the onset of addiction, itself a distortion of normal perception. Dr. Lewis freed himself from addiction and ended up studying it. At the age of 30 he traded in his pharmaceutical supplies for the life of a graduate student, eventually becoming a professor of developmental psychology, and then of neuroscience - his field for the last 12 years. This is the story of his journey, seen from the inside out.

The Effects of Drug Abuse on the Human Nervous System

The Effects of Drug Abuse on the Human Nervous System Book
Author : Bertha Madras,Michael Kuhar
Publisher : Elsevier
Release : 2013-11-15
ISBN : 0124186858
Language : En, Es, Fr & De

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Book Description :

Drug use and abuse continues to thrive in contemporary society worldwide and the instance and damage caused by addiction increases along with availability. The Effects of Drug Abuse on the Human Nervous System presents objective, state-of-the-art information on the impact of drug abuse on the human nervous system, with each chapter offering a specific focus on nicotine, alcohol, marijuana, cocaine, methamphetamine, MDMA, sedative-hypnotics, and designer drugs. Other chapters provide a context for drug use, with overviews of use and consequences, epidemiology and risk factors, genetics of use and treatment success, and strategies to screen populations and provide appropriate interventions. The book offers meaningful, relevant and timely information for scientists, health-care professionals and treatment providers. A comprehensive reference on the effects of drug addiction on the human nervous system Focuses on core drug addiction issues from nicotine, cocaine, methamphetamine, alcohol, and other commonly abused drugs Includes foundational science chapters on the biology of addiction Details challenges in diagnosis and treatment options

Chronic Pain and Addiction

Chronic Pain and Addiction Book
Author : M.R. Clark,G.J. Treisman
Publisher : Karger Medical and Scientific Publishers
Release : 2011-04-20
ISBN : 3805597266
Language : En, Es, Fr & De

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Book Description :

Patients with chronic pain understandably seek relief from their distress and discomfort, but many medications that alleviate pain are potentially addictive, and most chronic pain conditions only have a temporary response to opiate analgesic drugs. This volume reviews the fundamental topics that underlie the complex relationships of this controversial domain. The authors review behavioral models and practical methods for understanding and treating chronic pain and addiction including methods to formulate patients with complex comorbidity and screen patients with chronic pain for addictive liability. Finally, the authors describe the current findings from clinical and basic science that illuminate the role of opiates, cannabinoids and ketamine in the treatment of chronic pain. Up to date and comprehensive, this book is relevant to all professionals engaged in the care of patients with chronic pain or addiction and all others interested in these contemporary issues, particularly non-clinicians seeking clarity in the controversy over the best approach to patients with chronic pain.

Never Enough

Never Enough Book
Author : Judith Grisel
Publisher : Anchor
Release : 2020-01-14
ISBN : 0525434909
Language : En, Es, Fr & De

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Book Description :

A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

Substance and Nonsubstance Related Addiction Disorder Diagnosis and Treatment

Substance and Nonsubstance Related Addiction Disorder  Diagnosis and Treatment Book
Author : Subhash C. Bhatia,Frederick Petty,Teri Gabel
Publisher : Bentham Science Publishers
Release : 2017-02-09
ISBN : 1681083434
Language : En, Es, Fr & De

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Book Description :

Substance and Non substance Related Addiction Disorders: Diagnosis and Treatment is an accessible handbook about the two main types of addiction disorders. It is divided into three sections which cover 1) the scientific underpinnings of addiction disorders (neurobiology, addiction neural reward pathways, genetic and psychosocial basis of addiction, screening and treatment), 2) information about substances commonly used by addicts (pharmacology, diagnostics and treatment considerations) and 3) current understandings of the diagnosis and treatment of behavioral problems (such as gambling), respectively. Key features: -covers both substance abuse and behavioral problems -uses a reader friendly format with a patient education handout style -includes key learning points listed in each chapter -includes clinical vignettes which outline brief history, evaluation, diagnostic considerations with successful pharmacological, psychological and social interventions -includes references in each chapter The handbook meets the information needs of medical students and professionals (family physicians, nurses, addiction therapists, psychiatry residents, and other health care professionals) interested in the primary care of patients afflicted with addiction disorders.

Magnesium in the Central Nervous System

Magnesium in the Central Nervous System Book
Author : Robert Vink,Mihai Nechifor
Publisher : University of Adelaide Press
Release : 2011
ISBN : 0987073052
Language : En, Es, Fr & De

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Book Description :

The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.

Dispelling the Myths About Addiction

Dispelling the Myths About Addiction Book
Author : Institute of Medicine,Committee to Identify Strategies to Raise the Profile of Substance Abuse and Alcoholism Research
Publisher : National Academies Press
Release : 1997-11-10
ISBN : 9780309174596
Language : En, Es, Fr & De

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Book Description :

Every year about half a million men, women, and children in the United States die from the effects of using nicotine, alcohol, and illegal drugs: one of every four American deaths. Yet research to solve this terrible problem is often perceived as less important than other types of biomedical investigation. Focusing on four major classes of drugs with the greatest social and economic impact--nicotine, alcohol, opioids, and stimulants--Dispelling the Myths About Addiction examines what is known about addiction and what is needed to develop a talented cadre of investigators and to educate the public about addiction research. The committee explores these areas: Economic costs of addiction. What has been learned about addiction from research into basic neurobiology and the brain, psychosocial and behavioral factors, and epidemiology. Education and training of researchers and the research infrastructure. Public perceptions and their impact on public policy in this field. This volume outlines the challenges and opportunities in addiction research today and makes recommendations to educators, treatment professionals, public and private institutions, and others for how to build support for addiction research and treatment.

Addictive Disorders

Addictive Disorders Book
Author : Michael F. Fleming,Kristen Lawton Barry
Publisher : Year Book Medical Pub
Release : 1992
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Focuses on ambulatory care of patients adversely affected by addictive substances such as tobacco and alcohol. Topics include urine drug screening, medical withdrawal and detoxification, smoking cessation strategies, and substance abuse in adolescents, women and elderly patients.

Understanding Addiction as Self Medication

Understanding Addiction as Self Medication Book
Author : Edward J. Khantzian,Mark J. Albanese
Publisher : Rowman & Littlefield Publishers
Release : 2008-09-18
ISBN : 0742565513
Language : En, Es, Fr & De

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Book Description :

Addictive behaviors beg for an informed explanation to guide patients, families, students, and clinicians through the maddening and often incomprehensible nature of the addictions. Too often addiction is perceived to be merely a moral weakness or purely a brain disease, ignoring the deep personal pain that can permeate the lives of the addicted. But taking an honest look at the underlying emotional or mental issues can more clearly illuminate not only the causes of the addiction, but also the cure. Doctors Edward J. Khantzian and Mark J. Albanese, leading researchers in the field of addiction, see addictions primarily as a kind of self medication—a self medication that can temporarily soothe anxiety or pain, but that ultimately wreaks havoc on the lives and health of both the addicted and their loved ones. With practical advice, compelling case studies, and nuanced theory drawn from their years in clinical practice, Doctors Khantzian and Albanese look at the core reasons behind many addictions and provide a pathway to hope. Understanding Addiction as Self Medication looks at a range of addictions, including alcohol and substance abuse, and clearly explains how to understand other addictive behaviors through the lens of the Self Medication Hypothesis. This book provides a much-needed guide to both understanding addictions and working towards healing.

Addiction Medicine E Book

Addiction Medicine E Book Book
Author : Bankole Johnson
Publisher : Elsevier Health Sciences
Release : 2019-12-12
ISBN : 0323680534
Language : En, Es, Fr & De

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Book Description :

Integrating scientific knowledge with today’s most effective treatment options, Addiction Medicine: Science and Practice, 2nd Edition, provides a wealth of information on addictions to substances and behavioral addictions. It discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes. This essential text is ideal for anyone who deals with patients with addictions in clinical practice, including psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners. Clearly explains the role of brain function in drug taking and other habit-forming behaviors, and shows how to apply this biobehavioral framework to the delivery of evidence-based treatment. Provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding). Discusses current behavioral and medical therapies in depth, while also addressing social contexts that may affect personalized treatment. Contains new information on compliance-enhancing interventions, cognitive behavioral treatments, behavioral management, and other psychosocial interventions. Includes neurobiological, molecular, and behavioral theories of addiction, and includes a section on epigenetics. Contains up-to-date information throughout, including a new definition of status epilepticus, a current overview of Lennox Gastaut syndrome, and updates on new FDA-approved drugs for pediatric neurological disorders. Features expanded sections on evidence-based treatment options including pharmacotherapy, pharmacogenetics, and potential vaccines. Addresses addiction in regards to specific populations, including adolescents, geriatric, pregnant women, and health care professionals. Includes contributions from expert international authors, making this a truly global reference to addiction medicine.

Neuropathology of Drug Addictions and Substance Misuse Volume 1

Neuropathology of Drug Addictions and Substance Misuse Volume 1 Book
Author : Victor R. Preedy
Publisher : Academic Press
Release : 2016-03-07
ISBN : 0128003766
Language : En, Es, Fr & De

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Book Description :

Neuropathology of Drug Addictions and Substance Misuse, Volume One: Foundations of Understanding, Tobacco, Alcohol, Cannabinoids, Opioids and Emerging Addictions provides the latest research in an area that shows that the neuropathological features of one addiction are often applicable to those of others. The book also details how a further understanding of these commonalties can provide a platform for the study of specific addictions in greater depth, all in an effort to create new modes of understanding, causation, prevention, and treatment. The three volumes in this series address new research and challenges, offering comprehensive coverage on the adverse consequences of the most common drugs of abuse, with each volume serving to update the reader’s knowledge on the broader field of addiction, while also deepening our understanding of specific addictive substances. Volume One addresses tobacco, alcohol, cannabinoids, and opioids, with each section providing data on the general, molecular/cellular, and structural/functional neurological aspects of a given substance, along with a focus on the adverse consequences of addictions. Provides a modern approach on the pathology of substances of abuse, offering an evidence based ethos for understanding the neurology of addictions Fills an existing gap in the literature by proving a one-stop-shopping synopsis of everything to do with the neuropathology of drugs of addiction and substance misuse Includes a list of abbreviations, abstracts, applications to other addictions and substance misuse, mini-dictionary of terms, summary points, 6+ figures and tables, and full references in each chapter Offers coverage of preclinical, clinical, and population studies, from the cell to whole organs, and the genome to whole body