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A Theranostic And Precision Medicine Approach For Female Specific Cancers 2

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A Theranostic and Precision Medicine Approach for Female Specific Cancers

A Theranostic and Precision Medicine Approach for Female Specific Cancers Book
Author : Rama Rao Malla,Ganji Purnachandra Nagaraju
Publisher : Academic Press
Release : 2020-11-06
ISBN : 0128226927
Language : En, Es, Fr & De

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Book Description :

A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of biomedical field who need to understand the most recent and promising approaches to manage FSCs. Explores new diagnostic biomarkers surrounding the early detection and prognosis of FSCs Examines new genetic and molecularly targeted approaches for the treatment of these aggressive diseases Discusses new theranostic approaches that combine diagnosis and treatment through the use of nanotechnology in FSCs Addresses how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care

Design of Nanostructures for Theranostics Applications

Design of Nanostructures for Theranostics Applications Book
Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Release : 2018-01-15
ISBN : 0128136707
Language : En, Es, Fr & De

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Book Description :

Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry. Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders Assesses the pros and cons of using different nanomaterials for different types of treatment

Theranostic Imaging in Cancer Precision Medicine

Theranostic Imaging in Cancer Precision Medicine Book
Author : Marie-France Penet,Zaver Bhujwalla
Publisher : Frontiers Media SA
Release : 2022-02-22
ISBN : 2889744728
Language : En, Es, Fr & De

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Book Description :

Download Theranostic Imaging in Cancer Precision Medicine book written by Marie-France Penet,Zaver Bhujwalla, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma Volume 3

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma  Volume 3 Book
Author : Ganji Purnachandra Nagaraju,Sarfraz Ahmad
Publisher : Academic Press
Release : 2022-04-15
ISBN : 0323992846
Language : En, Es, Fr & De

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Book Description :

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma: Translational and Clinical Outcomes, Volume Three provides comprehensive information about ongoing research and clinical data on liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This updated volume discusses topics such as clinical and safety assessment of HCC patients, liver transplantation as a therapeutic option, immunotherapy interventions, and image-based surveillance. In addition, it discusses immunohistology of HCC-enabled precision medicine and artificial intelligence for hepatocellular carcinomas. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting. Provides best practices for the management of hepatocellular carcinoma in the clinical setting Discusses emerging treatment approaches based on artificial intelligence and precision medicine tools and techniques Brings updated information on international clinical trials for the treatment of HCC

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma Volume 1

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma  Volume 1 Book
Author : Ganji Purnachandra Nagaraju,Sujatha Peela
Publisher : Academic Press
Release : 2022-02-16
ISBN : 0323993648
Language : En, Es, Fr & De

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Book Description :

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume One: Biology and Pathophysiology provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. This volume discusses topics such as tumor microenvironment in hepatocellular carcinoma, endoplasmic reticulum stress and unfolded protein response, effects of cirrhosis and hepatitis on the prognosis of HCC, mitochondrial metabolism, next generation sequencing, and telomerase. In addition, it discusses exosomes role in HCC progression, metastasis and chemokines. This is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer for their research work or clinical setting. Provides an updated literature review and detailed understanding of liver cancer tumor biology Discusses abnormal changes in the liver caused, resulting from, or associated with hepatocellular carcinoma from a holistic view Presents the content with fully colored images and summarizing tables for easy understanding of complex topics

Multifunctional Theranostic Nanomedicines in Cancer

Multifunctional Theranostic Nanomedicines in Cancer Book
Author : Malay K. Das
Publisher : Academic Press
Release : 2021-03-26
ISBN : 0128217006
Language : En, Es, Fr & De

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Book Description :

Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer. Provides a comprehensive resource of recent scientific progress and novel applications of theranostic nanomedicines Discusses treatment options from a pharmaceutical sciences perspective Includes translational science and targeted CNS cancer treatment

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma Volume 2

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma  Volume 2 Book
Author : Ganji Purnachandra Nagaraju,Ramakrishna Vadde
Publisher : Academic Press
Release : 2022-04-10
ISBN : 0323993656
Language : En, Es, Fr & De

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Book Description :

Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume Two: Diagnosis, Therapeutic Targets and Molecular Mechanisms for Hepatocellular Carcinoma Progression provides comprehensive information about ongoing research and clinical data surrounding liver cancer. The book presents detailed descriptions about diagnostics and therapeutic options for easy understanding, with a focus on precision medicine approaches to improve treatment outcomes. The volume discusses topics such as computational approaches for identification of biomarkers, enzymes and pathways of HCC, circulating and epigenetic biomarkers, drug resistance, metabolic pathways, and small molecule-target therapies. In addition, it discusses immunotherapies, immune check point inhibitors and nanotechnology-based therapies. This book is a valuable resource for cancer researchers, oncologists, graduate students, hepathologists and members of biomedical research who need to understand more about liver cancer to apply in their research work or clinical setting. Provides detailed information on traditional and novel diagnostic tools for hepatocellular carcinoma Discusses promising targeted therapies, both available and in development, explaining the best option to use for specific cases Brings recent findings in immunotherapies, immune checkpoint inhibitors and nanotechnology-based therapeutic approaches for treatment of HCC

Nanocarriers for the Delivery of Combination Drugs

Nanocarriers for the Delivery of Combination Drugs Book
Author : Sanjula Baboota,Javed Ali
Publisher : Elsevier
Release : 2021-05-18
ISBN : 0128209402
Language : En, Es, Fr & De

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Book Description :

Nanocarriers for the Delivery of Combination Drugs focuses on the role of nanocarriers in the delivery of combination drugs for the management and treatment of various diseases. Nanocarriers belonging to the category of polymeric nanoparticles, dendrimers, lipidic nanocarriers (like nanoemulsions), liposomes, solid lipid nanoparticles, nanostructured lipid carriers are now being used in the drug delivery of combination drugs. This book helps readers assimilate all the information available surrounding the application of various nanocarrier technologies for the delivery of combination drugs of synthetic and natural origin, including small and large molecules. This is an important reference source for pharmaceutical scientists and biomaterials scientists who are looking to gain an increased understanding on how nanotechnology is improving the efficiency of combination drug delivery. Outlines how nanocarriers are used to enhance combination drug delivery systems Assesses the major challenges of delivering combination drugs successfully, and explains how nanocarriers can help meet these challenges Explores the characteristics of a variety of nanocarrier material types

Personalised Cancer Medicine

Personalised Cancer Medicine Book
Author : Anne Kerr
Publisher : Unknown
Release : 2021-02-23
ISBN : 9781526141026
Language : En, Es, Fr & De

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Book Description :

Download Personalised Cancer Medicine book written by Anne Kerr, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Clinical Nuclear Medicine

Clinical Nuclear Medicine Book
Author : Hojjat Ahmadzadehfar,Hans-Jürgen Biersack,Leonard M. Freeman,Lionel S. Zuckier
Publisher : Springer Nature
Release : 2020-05-06
ISBN : 3030394573
Language : En, Es, Fr & De

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Book Description :

In the new edition of this very successful book, European and North American experts present the state of the art in diagnostic and therapeutic radionuclide procedures. The aim is to examine established and emerging clinical applications in detail, rather than to consider everything included in the comprehensive texts already available within the field. This “practical” approach ensures that the book will be a valuable guide for nuclear medicine physicians, technologists, students, and interested clinicians alike. This edition of Clinical Nuclear Medicine has been extensively revised to take account of recent developments. The roles of SPECT/CT, PET/CT, and PET/MRI are clearly explained and illustrated, and the coverage extended to encompass, for example, novel PET tracers and therapeutic radionuclides, advanced techniques of brain imaging, and the development of theranostics. Readers will be fully persuaded of the ever-increasing value of nuclear medicine techniques in depicting physiology and function and complementing anatomic modalities such as CT, MRI, and ultrasound.

Targeted Cancer Imaging

Targeted Cancer Imaging Book
Author : Mehdi Azizi,Hadi Kokabi,Hassan Diant Moghadam,Mohammad Mehrmohammadi
Publisher : Academic Press
Release : 2021-12-10
ISBN : 012824514X
Language : En, Es, Fr & De

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Book Description :

Targeted Cancer Imaging: Design and Synthesis of Nanoplatforms based on Tumour Biology reviews and categorizes imaging and targeting approaches according to cancer type, highlighting new and safe approaches that involve membrane-coated nanoparticles, tumor cell-derived extracellular vesicles, circulating tumor cells, cell-free DNAs, and cancer stem cells, all with the goal of pointing the way to developing precise targeting and multifunctional nanotechnology-based imaging probes in the future. This book is highly multidisciplinary, bridging the knowledge gap between tumor biology, nanotechnology, and diagnostic imaging, and thus making it suitable for researchers ranging from oncology to bioengineering. Although considerable efforts have been conducted to diagnose, improve and treat cancer in the past few decades, existing therapeutic options are insufficient, as mortality and morbidity rates remain high. One of the best hopes for substantial improvement lies in early detection. Recent advances in nanotechnology are expected to increase our current understanding of tumor biology, allowing nanomaterials to be used for targeting and imaging both in vitro and in vivo experimental models. Gives understanding of cancer biology that is appropriate for students and researchers in engineering and nanotechnology Demonstrates cancer targeting strategies of multifunctional nanotechnology-based imaging probes Shows how to design, synthesize and apply cancer imaging nanostructures

Essentials of Cancer Genomic Computational Approaches and Precision Medicine

 Essentials of Cancer Genomic  Computational Approaches and Precision Medicine Book
Author : Nosheen Masood,Saima Shakil Malik
Publisher : Springer Nature
Release : 2020-03-20
ISBN : 9811510679
Language : En, Es, Fr & De

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Book Description :

This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy Book
Author : Ganji Purnachandra Nagaraju
Publisher : Academic Press
Release : 2019-02-26
ISBN : 0128176628
Language : En, Es, Fr & De

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Book Description :

Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery. Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy. Modulates the biologic properties of stroma in pancreatic cancer by targeting the several chemotherapy resistance mechanisms to impede their malignant property by introducing new strategies and drugs Provides information about on-going research as well as clinical data on pancreatic cancer and detailed descriptions about therapeutic options for easy understanding Utilizes full color figures to help the understanding of the content and tables for easy comparison of information as well as quick access to it

Panel of Tumor Markers Towards Precision Medicine in Genitourinary Cancers

Panel of Tumor Markers  Towards Precision Medicine in Genitourinary Cancers Book
Author : Daniela Terracciano,Matteo Ferro,Carlo Buonerba
Publisher : Frontiers Media SA
Release : 2022-06-14
ISBN : 2889762025
Language : En, Es, Fr & De

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Book Description :

Download Panel of Tumor Markers Towards Precision Medicine in Genitourinary Cancers book written by Daniela Terracciano,Matteo Ferro,Carlo Buonerba, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Precision Medicine in Oncology

Precision Medicine in Oncology Book
Author : Bulent Aydogan,James A. Radosevich
Publisher : John Wiley & Sons
Release : 2020-09-23
ISBN : 1119432448
Language : En, Es, Fr & De

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Book Description :

A FRESH EXAMINATION OF PRECISION MEDICINE'S INCREASINGLY PROMINENT ROLE IN THE FIELD OF ONCOLOGY Precision medicine takes into account each patient's specific characteristics and requirements to arrive at treatment plans that are optimized towards the best possible outcome. As the field of oncology continues to advance, this tailored approach is becoming more and more prevalent, channelling data on genomics, proteomics, metabolomics and other areas into new and innovative methods of practice. Precision Medicine in Oncology draws together the essential research driving the field forward, providing oncology clinicians and trainees alike with an illuminating overview of the technology and thinking behind the breakthroughs currently being made. Topics covered include: Biologically-guided radiation therapy Informatics for precision medicine Molecular imaging Biomarkers for treatment assessment Big data Nanoplatforms Casting a spotlight on this emerging knowledge base and its impact upon the management of tumors, Precision Medicine in Oncology opens up new possibilities and ways of working – not only for oncologists, but also for molecular biologists, radiologists, medical geneticists, and others.

Role of Transcription Factors in Gastrointestinal Malignancies

Role of Transcription Factors in Gastrointestinal Malignancies Book
Author : Ganji Purnachandra Nagaraju,Pallaval Veera Bramhachari
Publisher : Springer
Release : 2018-03-27
ISBN : 9811067287
Language : En, Es, Fr & De

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Book Description :

This book illustrates the importance of transcription factors in gastrointestinal cancer progression and metastasis with regard to understanding the mechanism and target definition in drug discovery. Further, it describes the complex issues associated with cancer cell growth and metastasis. The respective chapters provide detailed information on the various types of transcription factors (NF-kB, HIF-1, STAT-3, E2F1, and Sp1) and gastric-associated cancers (esophagus, stomach, colorectal, liver and pancreatic cancers) in connection with specific functional studies like cell cycle, angiogenesis, migration, invasion and apoptosis. These transcription factors control the expression of several signaling pathways involved in tumor growth, making them ideal targets for gastrointestinal cancer therapy. In closing, the book provides comprehensive descriptions of the major challenges associated with gastrointestinal cancer therapy.

The Drug Development Paradigm in Oncology

The Drug Development Paradigm in Oncology Book
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,National Cancer Policy Forum
Publisher : National Academies Press
Release : 2018-03-12
ISBN : 0309457947
Language : En, Es, Fr & De

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Book Description :

Advances in cancer research have led to an improved understanding of the molecular mechanisms underpinning the development of cancer and how the immune system responds to cancer. This influx of research has led to an increasing number and variety of therapies in the drug development pipeline, including targeted therapies and associated biomarker tests that can select which patients are most likely to respond, and immunotherapies that harness the body's immune system to destroy cancer cells. Compared with standard chemotherapies, these new cancer therapies may demonstrate evidence of benefit and clearer distinctions between efficacy and toxicity at an earlier stage of development. However, there is a concern that the traditional processes for cancer drug development, evaluation, and regulatory approval could impede or delay the use of these promising cancer treatments in clinical practice. This has led to a number of effortsâ€"by patient advocates, the pharmaceutical industry, and the Food and Drug Administration (FDA)â€"to accelerate the review of promising new cancer therapies, especially for cancers that currently lack effective treatments. However, generating the necessary data to confirm safety and efficacy during expedited drug development programs can present a unique set of challenges and opportunities. To explore this new landscape in cancer drug development, the National Academies of Sciences, Engineering, and Medicine developed a workshop held in December 2016. This workshop convened cancer researchers, patient advocates, and representatives from industry, academia, and government to discuss challenges with traditional approaches to drug development, opportunities to improve the efficiency of drug development, and strategies to enhance the information available about a cancer therapy throughout its life cycle in order to improve its use in clinical practice. This publication summarizes the presentations and discussions from the workshop.

Nanotheranostics for Cancer Applications

Nanotheranostics for Cancer Applications Book
Author : Prakash Rai,Stephanie A. Morris
Publisher : Springer
Release : 2018-11-12
ISBN : 3030017753
Language : En, Es, Fr & De

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Book Description :

This book is the first to focus specifically on cancer nanotheranostics. Each of the chapters that make up this comprehensive volume is authored by a researcher, clinician, or regulatory agency member known for their expertise in this field. Theranostics, the technology to simultaneously diagnose and treat a disease, is a nascent field that is growing rapidly in this era of personalized medicine. As the need for cost-effective disease diagnosis grows, drug delivery systems that can act as multifunctional carriers for imaging contrast and therapy agents could provide unique breakthroughs in oncology. Nanotechnology has enabled the development of smart theranostic platforms that can concurrently diagnose disease, start primary treatment, monitor response and initiate secondary treatments if required. In oncology, chemotherapeutics have been routinely used. Some drugs have proven effective but all carry risks of adverse side effects. There is growing interest in using remotely triggered drug delivery systems to limit cytotoxicity in the diseased area. This book reviews the use of theranostic nanoparticles for cancer applications over the past decade. First, it briefly discusses the challenges and limitations of conventional cancer treatments, and presents an overview of the use of nanotechnology in treating cancer. These introductory chapters are followed by those exploring cancer diagnosis and a myriad of delivery methods for nanotherapeutics. The book also addresses multifunctional platforms, treatment monitoring, and regulatory considerations. As a whole, the book aims to briefly summarize the development and clinical potential of various nanotheranostics for cancer applications, and to delineate the challenges that must be overcome for successful clinical development and implementation of such cancer theranostics.

My Beautiful Genome

My Beautiful Genome Book
Author : Lone Frank
Publisher : Simon and Schuster
Release : 2011-09-01
ISBN : 1851688641
Language : En, Es, Fr & De

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Book Description :

Internationally acclaimed science writer Lone Frank swabs up her DNA to provide the first truly intimate account of the new science of consumer-led genomics. She challenges the business mavericks intent on mapping every baby's genome, ponders the consequences of biological fortune-telling, and prods the psychologists who hope to uncover just how much or how little our environment will matter in the new genetic century - a quest made all the more gripping as Frank considers her family's and her own struggles with depression.

Diagnostic Immunohistochemistry

Diagnostic Immunohistochemistry Book
Author : David J. Dabbs
Publisher : Unknown
Release : 2002
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

17 world-renowned experts offer the most current information and reliable guidance on immunohistochemical diagnoses in surgical pathology and cytopathology. Introductory chapters cover cost modeling for immunohistochemistry and immunohistochemical techniques. The following chapters utilize an organ systems and diseases approach to diagnostic tumor pathology. A newly updated book that our laboratory staff have found very useful in our day to day work Reviewed by: PathLab.org, Sept 2014 ...It also acts as an up-to-date bench-top reference tool. It is an easy-to-read, wellpresented text that I would recommend as a 'must have' for every pathology department. Reviewed by: Dr Gemma Petts, Imperial College London on behalf of The Bulletin of The Royal College of Pathologists, Oct 2014 Consistently organized chapters for quick access to vital information Each chapter stands alone, providing all the information you might need on a specific topic Quick-reference boxes summarize the most important diagnostic points at the end of each text Section Colour photographs and illustrations reinforce key diagnostic points