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A Roadmap To Nonhematopoietic Stem Cell Based Therapeutics

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A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics

A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics Book
Author : Xiao-Dong Chen
Publisher : Academic Press
Release : 2018-08-31
ISBN : 0128119217
Language : En, Es, Fr & De

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Book Description :

A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Controversies in Latin American Bioethics

Controversies in Latin American Bioethics Book
Author : Eduardo Rivera-López,Martin Hevia
Publisher : Springer
Release : 2019-06-19
ISBN : 303017963X
Language : En, Es, Fr & De

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Book Description :

This book offers a first rate selection of academic articles on Latin American bioethics. It covers different issues, such as vulnerability, abortion, biomedical research with human subjects, environment, exploitation, commodification, reproductive medicine, among others. Latin American bioethics has been, to an important extent, parochial and unable to meet stringent international standards of rational philosophical discussion. The new generations of bioethicists are changing this situation, and this book demonstrates that change. All articles are written from the perspective of Latin American scholars from several disciplines such as philosophy and law. Working with the tools of analytical philosophy and jurisprudence, this book defends views with rational argument, and opening for pluralistic discussion.

Regenerative Therapy Using Blood Derived Stem Cells

Regenerative Therapy Using Blood Derived Stem Cells Book
Author : David S. Allan,Dirk Strunk
Publisher : Springer Science & Business Media
Release : 2011-11-16
ISBN : 9781617794711
Language : En, Es, Fr & De

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Book Description :

Blood has long been viewed as a conduit for therapy, stemming from the ancient days of phlebotomy to remove evil humors to the development of successful blood transfusions to replace missing blood components. The identification and characterization of hematopoietic stem cells by Drs. Till and McCulloch revolutionized the field and soon after, non-hematopoietic stem and progenitor cells were characterized from the blood and bone marrow. Some of these cell types and various blood-derived cell lineages are involved in the repair of various types of tissue damage that span the spectrum of medical disorders. The goal of this book is to provide an up-to-date review of the various types of blood-derived cells with regenerative capacity, identify opportunities for intervention by examining specific clinical applications, and recognize the regulatory environment that will encompass future therapies in regenerative medicine.

Stem Cell and Gene Therapy for Cardiovascular Disease

Stem Cell and Gene Therapy for Cardiovascular Disease Book
Author : Emerson C. Perin,Leslie W. Miller,Doris Taylor,James T. Willerson
Publisher : Academic Press
Release : 2015-08-21
ISBN : 0128018631
Language : En, Es, Fr & De

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Book Description :

Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic. Provides information on stem and gene therapy medical trials from contributors and specialists around the world, including not only what has been completed, but also what is planned for future research and trials Presents topics that can be applied to allogeneic cells, mesenchymal cells, gene therapy, cardiomyoctyes, iPS cells, MAPC's, and organogenesis Covers the three areas with the greatest clinical trials to date: chronic limb ischemia, chronic angina, and acute MI Covers the prevailing opinions on how to harness the body’s natural repair mechanisms Ideal resource for cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals

Blood Cell

Blood Cell Book
Author : Terry E. Moschandreou
Publisher : BoD – Books on Demand
Release : 2012-09-21
ISBN : 9535107534
Language : En, Es, Fr & De

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Book Description :

The editor has incorporated scientific contributions from a diverse group of leading researchers in the field of hematology and related blood cell research. This book aims to provide an overview of current knowledge pertaining to our understanding of hematology. The main subject areas will include blood cell morphology and function, the pathophysiology and genetics of hematological disorders and malignancies, blood testing and typing, and the processes governing hematopoiesis. Blood cell physiology, biochemistry and blood flow are covered in this book. This text is designed for hematologists, pathologists and laboratory staff in training and in practice. The work presented in this book will be of benefit to medical students and to researchers of hematology and blood flow in the microcirculation.This book is written primarily for those who have some knowledge of chemistry, biochemistry and general hematology. The authors of each section bring a strong clinical emphasis to the book.