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A Roadmap For Curing Cancer Alzheimers And Cardiovascular Disease

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A Roadmap for Curing Cancer Alzheimer s and Cardiovascular Disease

A Roadmap for Curing Cancer  Alzheimer s  and Cardiovascular Disease Book
Author : Paul J. Marangos
Publisher : Academic Press
Release : 2017-04-25
ISBN : 012812797X
Language : En, Es, Fr & De

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Book Description :

Cancer, dementia, and cardiovascular disease are responsible for almost two million deaths each year in the United States alone and represent the largest immediate threat to humanity. Over the last century, we have made spectacular advances that have transformed our society – splitting the atom, space travel, telecommunications, and the Internet – but with medical research focused mostly on science for the sake of science, it has yielded precious few cures. A Roadmap for Curing Cancer, Alzheimer’s, and Cardiovascular Disease represents a "first of its kind" effort to address both the reasons for this and to posit solutions to fix our broken system, in an effort to finally end this cure crisis. Dr. Marangos draws on 45 years of experience in every aspect of the biomedical R&D field, from basic drug discovery research at the NIH to the co-founding of five drug companies. He has published 252 research papers and edited four books on drug discovery, is co-inventor on 14 patents, and founded "The Journal of Molecular Neuroscience". He argues that from a development perspective, the regulatory, patent, and legal hurdles that force industry to pursue so-called "me-too" drugs rather than cures for terminal diseases must be re-thought. Leadership accountability, strategy, focus, and urgency need to be re-evaluated, and major reforms to the NIH, FDA, and patent codes are proposed.to remedy these impediments to cures. Written for anyone frustrated with the seemingly endless threat of terminal disease, this book seeks to inform, energize, and provide the rationale for the public and industry stakeholders, as well as clinicians and researchers, to resurrect the physician-patient relationship and demand that we get serious about ridding society of this scourge on humanity. - This work contains the views and opinions of the author and are in no way intended to harm the reputation of any person, agency, organization, or commercial entity discussed herein. - First comprehensive analysis of the failures in curing cancer, Alzheimer’s, and cardiovascular disease with solutions proposed Defines deficiencies in academic life science research, including conflicting incentives, QA/QC issues, and how to fix them Provides a rationale for FDA reform especially as it relates to terminal disease drugs Details how a reformed NIH, regulators, and industry can partner to form a NASA-type effort to speed cures of terminal diseases Provides the first detailed roadmap for life science researchers to conquer terminal disease

The Roadmap to 100

The Roadmap to 100 Book
Author : Walter M. Bortz, II, MD,Randall Stickrod
Publisher : St. Martin's Press
Release : 2010-04-13
ISBN : 9780230107625
Language : En, Es, Fr & De

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Book Description :

With a baby boomer turning sixty every ten seconds, we are rapidly becoming an aging society. But cutting edge research on the connection between age and disease shows us that many of the preconceptions we had about how to grow old need a second look. This groundbreaking book is full of take-away prescriptive advice which the nearly seventy-five million boomers in this nation will value. Top gerontologist and Stanford medical school professor Dr. Walter Bortz and co-author Randall Stickrod draw on new science and a thirty-year longitudinal study of centenarians to show that: • Genetics plays a smaller role in aging than previously thought • Senility, dementia, and other diseases of the elderly, are largely preventable and not an inevitable consequence of aging • Engagement, through sexual relationships, social interaction, and professional activity, is a key factor in long, healthy lives • Physical fitness can recover at least 30 years of aging Filled with in-depth insight and practical advice, The Roadmap to 100 gives you the power to control your own destiny and live well beyond 100.

A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics

A Roadmap to Nonhematopoietic Stem Cell Based Therapeutics Book
Author : Xiao-Dong Chen
Publisher : Academic Press
Release : 2018-08-31
ISBN : 0128119217
Language : En, Es, Fr & De

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Book Description :

A Roadmap to Non-hematopoietic Stem Cell-Based Therapeutics: From the Bench to the Clinic is a resource that provides an overview of the principles of stem cell therapy, the promises and challenges of using stem cells for treating various clinical conditions, and future perspectives. The overall goal is to facilitate the translation of basic research on stem cells to clinical applications. The properties of stem cells from various sources are reviewed and the advantages and disadvantages of each for clinical use are discussed. Modifying stem cell properties through preconditioning strategies using physical, chemical, genetic, and molecular manipulation to improve cell survival, increase cell differentiation potential, enhance production of paracrine factors, and facilitate homing to the site of injury or disease upon transplantation are reviewed. Various routes of stem cell administration and dosing, and the duration of effects, are explored. Individual chapters are written by experts in the field and focus on the use of stem cells in treating various degenerative diseases, autoimmune diseases, wound healing, cardiovascular disease, spinal cord injury, oral and dental diseases, and skeletal disorders. Finally, experts in the regulatory arena discuss mechanisms used in different countries for approving the use of stem cells to treat diseases and many common issues that are typically encountered while seeking approval for this class of therapeutic agent. Offers advanced students, as well as new researchers, an overview of the principles of stem cell therapy Discusses a wide array of pressing clinical issues with stem cell-based therapies so that new ideas in the laboratory can be efficiently translated to the clinic through better designed clinical trials Helps clarify current regulatory mechanisms so that the safe use of stem cells for treating a variety of diseases can move forward Fosters cross-disciplinary dialogue between research scientists and physicians to accelerate the safe implementation of efficacious cell therapies

Geriatric Psycho Oncology

Geriatric Psycho Oncology Book
Author : Jimmie C. Holland,Talia Weiss Wiesel,Christian J. Nelson,Andrew J. Roth,Yesne Alici
Publisher : Oxford University Press
Release : 2015-02-03
ISBN : 0199361487
Language : En, Es, Fr & De

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Book Description :

Geriatric Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of older adults living with cancer and their families. Chapters cover a wide range of topics including screening tools and interventions, psychiatric emergencies and disorders, physical symptom management, communication issues, and issues specific to common cancer sites. A resource section is appended to provide information on national services and programs. This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating older cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Geriatric Psycho-Oncology is an ideal resource for helping oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing or adding psychosocial components to existing clinics.

Metabolism and Medicine

Metabolism and Medicine Book
Author : Brian Fertig
Publisher : CRC Press
Release : 2022-01-26
ISBN : 1000472132
Language : En, Es, Fr & De

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Book Description :

Chronic disease states of aging should be viewed through the prism of metabolism and biophysical processes at all levels of physiological organization present in the human body. This book describes the building blocks of understanding from a reasonable but not high-level technical language viewpoint, employing the perspective of a clinical physician. It brings together concepts from five specific branches of physics relevant to biology and medicine, namely, biophysics, classical electromagnetism, thermodynamics, systems biology and quantum mechanics. Key Features: Broad and up-to-date overview of the field of metabolism, especially connecting the spectrum of topics that range from modern physical underpinnings with cell biology to clinical practice. Provides a deeper basic science and interdisciplinary understanding of biological systems that broaden the perspectives and therapeutic problem solving. Introduces the concept of the Physiological Fitness Landscape, which is inspired by the physics of phase transitions This first volume in a two-volume set, primarily targets an audience of clinical and science students, biomedical researchers and physicians who would benefit from understanding each other’s language.

Outlive

Outlive Book
Author : Peter Attia,Bill Gifford
Publisher : Random House
Release : 2023-03-28
ISBN : 1529910897
Language : En, Es, Fr & De

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Book Description :

This is the ultimate manual for longevity. For all its successes, mainstream medicine has failed to make much progress against the diseases of ageing that kill most people: heart disease, cancer, Alzheimer's disease, and type 2 diabetes. Too often, it intervenes with treatments too late, prolonging lifespan at the expense of quality of life. Dr Peter Attia, the world's top longevity expert, believes we must replace this outdated framework with a personalised, proactive strategy for longevity. This isn't 'biohacking,' it's science: a well-founded strategic approach to extending lifespan while improving our physical, cognitive and emotional health, making each decade better than the one before. With Outlive's practical advice and roadmap, you can plot a different path for your life, one that lets you outlive your genes to make each decade better than the one before.

Oxford Handbook of Cancer Nursing

Oxford Handbook of Cancer Nursing Book
Author : Michael Tadman,Dave Roberts,Mark Foulkes
Publisher : Oxford University Press
Release : 2019-06-07
ISBN : 0191059218
Language : En, Es, Fr & De

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Book Description :

This second edition of the Oxford Handbook of Cancer Nursing is an essential aid to the practising cancer nurse. It provides a quick reference to the key issues in cancer nursing, and a concise and systematic account of all of the main areas of cancer nursing practice. Filled with key tips and reflection points, each chapter supports professional development for the reader. The patient, their family, and the experience of cancer are at the heart of this handbook. For the new edition there is a greater focus on survivorship, drawing on recent developments in the area. The Oxford Handbook of Cancer Nursing promotes a multidisciplinary approach to cancer care, with references to current best evidence and the latest developments in treatment. Detailed guidance on complex aspects of care are outlined, integrating both psychosocial and physical care to better treat the whole patient. Written by experienced nurses, the book is laid out to enable quick access to precise, targeted information on the vast majority of potential clinical scenarios.

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2006 National Institutes of Health

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2006  National Institutes of Health Book
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2006 National Institutes of Health book written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2006

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2006 Book
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2006 book written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

VA Research on Alzheimer s Disease Parkinson s Disease and Diabetes

VA Research on Alzheimer s Disease  Parkinson s Disease  and Diabetes Book
Author : United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Oversight and Investigations
Publisher : Unknown
Release : 2005
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download VA Research on Alzheimer s Disease Parkinson s Disease and Diabetes book written by United States. Congress. House. Committee on Veterans' Affairs. Subcommittee on Oversight and Investigations, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Endothelial Progenitor Cells

Endothelial Progenitor Cells Book
Author : Carmela Rita Balistreri
Publisher : Springer
Release : 2017-05-25
ISBN : 3319551078
Language : En, Es, Fr & De

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Book Description :

This book explores the role of endothelial progenitor cells (EPCs) in the context of regenerative medicine (RegMed). In particular, it reveals the value of RegMed as a new TM branch intended to improve the health and quality of life, by restoring, maintaining or enhancing tissue and functions of organs. The book is divided into three chapters, the first of which describes the relevance of translational medicine (TM) as a new research approach to counteract the imposing challengeof age-related diseases. Of the diverse RegMed approaches, particular attention is paid to stem/progenitor cell-based therapies, their benefits and shortcomings, as well as to the description of types of stem and progenitor cells considered for regenerative cell therapies, such as EPCs as emerging candidates for RegMed applications. In turn, the second chapter outlines the clinical relevance of EPCs as both potential predictors, diagnostic and prognostic biomarkers of age-related diseases and therapeutic agents,discussing their advantages, disadvantages, and conflicting data. Chapter three proposes a potential roadmap for revising the findings and creating a clearer picture of valid data, which can provide support for various important aspects, i.e.isolating and characterizing EPCs by establishing standardized criteria for EPC research, identifying appropriate sub-populations for cell therapy, timing, dosing, priming of cells,and defining delivery modes for different applications. The book concludes with an overview of innovative strategies that could improve the efficacy of cell therapy at all levels, including cell priming, bio-nanotechnology, and tissue engineering.

The Law of Biologic Medicine

The Law of Biologic Medicine Book
Author : United States. Congress. Senate. Committee on the Judiciary
Publisher : Unknown
Release : 2004
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download The Law of Biologic Medicine book written by United States. Congress. Senate. Committee on the Judiciary, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2007

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2007 Book
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release : 2006
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2007 book written by United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Departments of Labor and Health and Human Services Education and Related Agencies Appropriations

Departments of Labor  and Health and Human Services  Education  and Related Agencies Appropriations Book
Author : United States. Congress. Senate. Committee on Appropriations
Publisher : Unknown
Release : 2007
ISBN : 0987650XXX
Language : En, Es, Fr & De

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Book Description :

Download Departments of Labor and Health and Human Services Education and Related Agencies Appropriations book written by United States. Congress. Senate. Committee on Appropriations, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

The Disease Delusion

The Disease Delusion Book
Author : Dr. Jeffrey S. Bland
Publisher : Harper Collins
Release : 2014-05-06
ISBN : 0062290754
Language : En, Es, Fr & De

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Book Description :

For decades, Dr. Jeffrey Bland has been on the cutting edge of Functional Medicine, which seeks to pinpoint and prevent the cause of illness, rather than treat its symptoms. Managing chronic diseases accounts for three quarters of our total healthcare costs, because we’re masking these illnesses with pills and temporary treatments, rather than addressing their underlying causes, he argues. Worse, only treating symptoms leads us down the path of further illness. In The Disease Delusion, Dr. Bland explains what Functional Medicine is and what it can do for you. While advances in modern science have nearly doubled our lifespans in only four generations, our quality of life has not reached its full potential. Outlining the reasons why we suffer chronic diseases from asthma and diabetes to obesity, arthritis and cancer to a host of other ailments, Dr. Bland offers achievable, science-based solutions that can alleviate these common conditions and offers a roadmap for a lifetime of wellness.

The XX Brain

The XX Brain Book
Author : Lisa Mosconi PhD
Publisher : Penguin
Release : 2020-03-10
ISBN : 0593083113
Language : En, Es, Fr & De

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Book Description :

The instant New York Times bestseller! "In The XX Brain, Lisa meticulously guides us in the ways we can both nourish and protect ourselves, body and mind, to ensure our brains remain resilient throughout our lives." --from the foreword by Maria Shriver The first book to address cognitive enhancement and Alzheimer's prevention specifically in women--and to frame brain health as an essential component of Women's Health. In this revolutionary book, Dr. Lisa Mosconi, director of the Women's Brain Initiative at Weill Cornell Medical College, provides women with the first plan to address the unique risks of the female brain. Until now, medical research has focused on "bikini medicine," assuming that women are essentially men with breasts and tubes. Yet women are far more likely than men to suffer from anxiety, depression, migraines, brain injuries, and strokes. They are also twice as likely to end their lives suffering from Alzheimer's disease, even when their longer lifespans are taken into account. But in the past, the female brain has received astonishingly little attention and was rarely studied by medical researchers-- resulting in a wealth of misinformation about women's health. The XX Brain confronts this crisis by revealing how the two powerful X chromosomes that distinguish women from men impact the brain first and foremost and by focusing on a key brain-protective hormone: estrogen. Taking on all aspects of women's health, including brain fog, memory lapses, depression, stress, insomnia, hormonal imbalances, and the increased risk of dementia, Dr. Mosconi introduces cutting-edge, evidence-based approaches to protecting the female brain, including a specific diet proven to work for women, strategies to reduce stress, and useful tips for restorative sleep. She also examines the controversy about soy and hormonal replacement therapy, takes on the perils of environmental toxins, and examines the role of our microbiome. Perhaps best of all, she makes clear that it is never too late to take care of yourself. The XX Brain is a rallying cry for women to have full access to information regarding what is going on in their brains and bodies as well as a roadmap for the path to optimal, lifelong brain health.

Behavioral Intervention Research in Hospice and Palliative Care

Behavioral Intervention Research in Hospice and Palliative Care Book
Author : George Demiris,Debra Parker Oliver,Karla T. Washington
Publisher : Academic Press
Release : 2018-10-12
ISBN : 0128144505
Language : En, Es, Fr & De

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Book Description :

Behavioral Intervention Research in Hospice and Palliative Care: Building an Evidence Base sets forth research considerations and guidelines to build evidence-based interventions to improve end-of-life care. It is an in-depth introduction to implementation research and showcases how a clinical need is identified to inform an intervention. The book extensively examines the various phases of intervention research, including design, implementation, evaluation, dissemination and translation. The book focuses on methodological, ethical and practical issues. The science behind the quality of hospice and palliative care lags behind that of traditional medical practice, despite the continuous growth of palliative care interdisciplinary teams. Researching, developing and testing strategies is essential to advancing the effectiveness and value of this care. Informs readers how to conduct intervention research toward identifying best care Advises readers on design, implementation and evaluation of research Provides step-by-step templates to develop an intervention study Includes mock protocols from successful intervention trials Synthesizes lessons learned by established intervention researchers in hospice and palliative care

Life Force

Life Force Book
Author : Tony Robbins,Peter H. Diamandis
Publisher : Simon and Schuster
Release : 2022-02-08
ISBN : 1982121734
Language : En, Es, Fr & De

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Book Description :

INSTANT #1 NEW YORK TIMES BESTSELLER Transform your life or the life of someone you love with Life Force—the newest breakthroughs in health technology to help maximize your energy and strength, prevent disease, and extend your health span—from Tony Robbins, author of the #1 New York Times bestseller Money: Master the Game. What if there were scientific solutions that could wipe out your deepest fears of falling ill, receiving a life-threatening diagnosis, or feeling the effects of aging? What if you had access to the same cutting-edge tools and technology used by peak performers and the world’s greatest athletes? In a world full of fear and uncertainty about our health, it can be difficult to know where to turn for actionable advice you can trust. Today, leading scientists and doctors in the field of regenerative medicine are developing diagnostic tools and safe and effective therapies that can free you from fear. In this book, Tony Robbins, the world’s #1 life and business strategist who has coached more than fifty million people, brings you more than 100 of the world’s top medical minds and the latest research, inspiring comeback stories, and amazing advancements in precision medicine that you can apply today to help extend the length and quality of your life. This book is the result of Robbins going on his own life-changing journey. After being told that his health challenges were irreversible, he experienced firsthand how new regenerative technology not only helped him heal but made him stronger than ever before. Life Force will show you how you can wake up every day with increased energy, a more bulletproof immune system, and the know-how to help turn back your biological clock. This is a book for everyone, from peak performance athletes, to the average person who wants to increase their energy and strength, to those looking for healing. Life Force provides answers that can transform and even save your life, or that of someone you love.

Knowing What Works in Health Care

Knowing What Works in Health Care Book
Author : Institute of Medicine,Board on Health Care Services,Committee on Reviewing Evidence to Identify Highly Effective Clinical Services
Publisher : National Academies Press
Release : 2008-05-29
ISBN : 0309113563
Language : En, Es, Fr & De

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Book Description :

There is currently heightened interest in optimizing health care through the generation of new knowledge on the effectiveness of health care services. The United States must substantially strengthen its capacity for assessing evidence on what is known and not known about "what works" in health care. Even the most sophisticated clinicians and consumers struggle to learn which care is appropriate and under what circumstances. Knowing What Works in Health Care looks at the three fundamental health care issues in the United States-setting priorities for evidence assessment, assessing evidence (systematic review), and developing evidence-based clinical practice guidelines-and how each of these contributes to the end goal of effective, practical health care systems. This book provides an overall vision and roadmap for improving how the nation uses scientific evidence to identify the most effective clinical services. Knowing What Works in Health Care gives private and public sector firms, consumers, health care professionals, benefit administrators, and others the authoritative, independent information required for making essential informed health care decisions.