Skip to main content

A Laboratory Guide To The Tight Junction

Download A Laboratory Guide To The Tight Junction Full eBooks in PDF, EPUB, and kindle. A Laboratory Guide To The Tight Junction is one my favorite book and give us some inspiration, very enjoy to read. you could read this book anywhere anytime directly from your device.

A Laboratory Guide to the Tight Junction

A Laboratory Guide to the Tight Junction Book
Author : Jianghui Hou
Publisher : Academic Press
Release : 2020-04-24
ISBN : 0128226439
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

A Laboratory Guide to the Tight Junction offers broad coverage of the unique methods required to investigate its characteristics. The methods are described in detail, including its biochemical and biophysical principles, step-by-step process, data analysis, troubleshooting, and optimization. The coverage includes various cell, tissue, and animal models. Chapter 1 provides the foundations of cell biology of tight junction. Chapter 2 covers the Biochemical approaches for paracellular channels and is followed by chapter 3 providing the Biophysical approaches. Chapter 4 describes and discusses Histological approaches for tissue fixation and preparation. Chapter 5 discusses Light microscopy, while chapter 6 presents Electron microscopic approaches. Chapter 7 covers Transgenic manipulation in cell cultures, including DNA and siRNA, Mutagenesis, and viral infection. Chapter 8 covers transgenic manipulation in mice, including: Knockout, Knockin, siRNA knockdown, GFP/LacZ reporter, and overexpression. The final chapter discusses the future developments of new approaches for tight junction research. Researchers and advanced students in bioscience working on topics of cell junction, ion channel and membrane protein will benefit from the described methods. Clinicians and pathologists interested in tissue barrier diseases will also benefit from the biochemical and biophysical characterization of tight junctions in organ systems, and their connection to human diseases. Provides consistent and detailed research methods Covers various cell, tissue and animal models Includes step-by-step guidance from beginner to sophisticated levels

A Laboratory Guide to Human Physiology

A Laboratory Guide to Human Physiology Book
Author : Stuart Ira Fox
Publisher : Unknown
Release : 1984
ISBN : 9780697047243
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download A Laboratory Guide to Human Physiology book written by Stuart Ira Fox, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Claudins

Claudins Book
Author : Kursad Turksen
Publisher : Humana Press
Release : 2011-07-02
ISBN : 9781617791840
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Since the initial discovery of the claudins, the field of tight junctions and cell polarity has become increasingly energized, mainly due to the fact that the claudins have provided an opportunity to understand the molecular basis of the tight junction function and their tissue specific roles. In Claudins: Methods and Protocols, experts and pioneers in the field provide an extensive collection of techniques involving these tight junction proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective topics, detailed lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Claudins: Methods and Protocols serves as an ideal guide for all scientists seeking to further our understanding of this vital area of research.

A Laboratory Guide to the Mammalian Embryo

A Laboratory Guide to the Mammalian Embryo Book
Author : David K. Gardner,Michelle Lane,Andrew J. Watson
Publisher : Oxford University Press
Release : 2004-01-08
ISBN : 9780195142266
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Never before has there been such a comprehensive book of protocols. This compendium offers a full range of research techniques-from cell culture, to biochemical, to microscopic and genetic. More focused books, like Cold Spring Harbor's Manipulating the Mouse Embryo, are similar though more narrow in scope. This book will appeal to a broad range of researchers, from basic experimental scientists to clinical and animal scientists.

The Paracellular Channel

The Paracellular Channel Book
Author : Jianghui Hou
Publisher : Academic Press
Release : 2018-06-08
ISBN : 0128146362
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization. Offers integrated coverage of all key aspects of the paracellular channel, an understudied field that may hold key insights into some of the most mysterious aspects of physiology Targets different levels of expertise, spanning from graduate students, interns and clinical fellows, to seasoned researchers that study functions, regulation and dysfunctions of different tissue barriers Provides a cohesive and unifying picture that describes the critical functions of paracellular channels (tight junctions) in different tissues

Human Stem Cell Manual

Human Stem Cell Manual Book
Author : Suzanne Peterson,Jeanne F. Loring
Publisher : Academic Press
Release : 2012-10-22
ISBN : 0123854741
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

This manual is a comprehensive compilation of "methods that work" for deriving, characterizing, and differentiating hPSCs, written by the researchers who developed and tested the methods and use them every day in their laboratories. The manual is much more than a collection of recipes; it is intended to spark the interest of scientists in areas of stem cell biology that they may not have considered to be important to their work. The second edition of the Human Stem Cell Manual is an extraordinary laboratory guide for both experienced stem cell researchers and those just beginning to use stem cells in their work. Offers a comprehensive guide for medical and biology researchers who want to use stem cells for basic research, disease modeling, drug development, and cell therapy applications. Provides a cohesive global view of the current state of stem cell research, with chapters written by pioneering stem cell researchers in Asia, Europe, and North America. Includes new chapters devoted to recently developed methods, such as iPSC technology, written by the scientists who made these breakthroughs.

Oral Histology Laboratory Guide

Oral Histology Laboratory Guide Book
Author : Anonim
Publisher : Unknown
Release : 1978
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download Oral Histology Laboratory Guide book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Human Neuroanatomy

Human Neuroanatomy Book
Author : J. Edward Bruni,Donald G. Montemurro
Publisher : Oxford University Press, USA
Release : 2009
ISBN : 0195371429
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

The Human Brain in Dissection will significantly update the previous edition published in 1988. The last 20 years have sen a significant shift in the way that neuroanatomy is taught in both undergraduate and graduate neuroscience courses, as well as doctorate courses: not only has the time allocated for these courses been reduced, but the methodologies for teaching have become more focused and specific due to these time constraints. The Human Brain in Dissection, Third Edition will provide detailed features of the human brain with the above limitations in mind. 50 new plates will be added to the existing 123 in order to permit the student to see all salient structures and to visualize microscopic structures of the brain stem and spinal cord. Each chapter will cover a specific are of the human brain in such a way that each chapter can be taught in one two-hour neuroanatomy course. New to this edition is the inclusion of a section in each chapter on clinically relevant examples. Each chapter will also include a specific laboratory exercise. And finally, the author has included a question and answer section that is relevant to the USMLE, as as recommended readings, neither of which were included in the previous editions. This new edition of The Human Brain in Dissection will allow the student to: understand basic principles of cellular neuroscience; learn gross and microscopic anatomy of the central nervous system (Brain, brainstem, and spinal cord); relate the anatomy of central neural pathways to specific functional systems; be able to localize and name a CNS legion when presented with neurological symptoms, and appreciate higher cortical functions and how they relate to the practice of neurology. neuroscience

NIH Guide for Grants and Contracts

NIH Guide for Grants and Contracts Book
Author : National Institutes of Health (U.S.)
Publisher : Unknown
Release : 2022-09-26
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download NIH Guide for Grants and Contracts book written by National Institutes of Health (U.S.), available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

General Zoology Laboratory Guide

General Zoology Laboratory Guide Book
Author : Charles F. Lytle,John R. Meyer
Publisher : McGraw-Hill Science, Engineering & Mathematics
Release : 2004-02-28
ISBN : 9780072349009
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

General Zoology Laboratory Manual is ideal for the laboratory that emphasizes the dissection and microscopic study of live and preserved specimens. Recognized for its accuracy and readability, this manual is comprehensive in its representation of the major groups of animal phyla.This new edition is suitable for a wide range of course needs and structures.

Current Trends in Exploiting Molecular Signaling in Bacteria Host Crosstalk

Current Trends in Exploiting Molecular Signaling in Bacteria Host Crosstalk Book
Author : Monica Cartelle Gestal,Carmen Mariana Chifiriuc,Alina Maria Holban,Karl Kuchler
Publisher : Frontiers Media SA
Release : 2022-06-27
ISBN : 2889764303
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download Current Trends in Exploiting Molecular Signaling in Bacteria Host Crosstalk book written by Monica Cartelle Gestal,Carmen Mariana Chifiriuc,Alina Maria Holban,Karl Kuchler, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development Book
Author : Ali S. Faqi
Publisher : Academic Press
Release : 2016-11-03
ISBN : 0128036214
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology

The Impact of Food Bioactives on Health

The Impact of Food Bioactives on Health Book
Author : Kitty Verhoeckx,Paul Cotter,Iván López-Expósito,Charlotte Kleiveland,Tor Lea,Alan Mackie,Teresa Requena,Dominika Swiatecka,Harry Wichers
Publisher : Springer
Release : 2015-04-29
ISBN : 3319161040
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.

The Laboratory Guide

The Laboratory Guide Book
Author : Sir Arthur Herbert CHURCH
Publisher : Unknown
Release : 1894
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download The Laboratory Guide book written by Sir Arthur Herbert CHURCH, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

A Practical Guide to the Histology of the Mouse

A Practical Guide to the Histology of the Mouse Book
Author : Cheryl L. Scudamore
Publisher : John Wiley & Sons
Release : 2013-12-24
ISBN : 1118789474
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues. This book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions. This will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology. Written by experienced pathologists and specifically tailored to the needs of scientists and histologists Full colour throughout Provides advice on sampling tissues, necropsy and recording data Includes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation

NIH Guide for Grants and Contracts

NIH Guide for Grants and Contracts Book
Author : Anonim
Publisher : Unknown
Release : 1978
ISBN : 0987650XXX
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download NIH Guide for Grants and Contracts book written by , available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Foodborne Enterobacteriaceae of Animal Origin Epidemic Characteristics of Drug Resistance Pathogenic Mechanisms and Novel Control Measures

Foodborne Enterobacteriaceae of Animal Origin  Epidemic Characteristics of Drug Resistance  Pathogenic Mechanisms  and Novel Control Measures Book
Author : Fangkun Wang,Dongyan Niu,Zhang Wan Jiang
Publisher : Frontiers Media SA
Release : 2021-11-25
ISBN : 288971697X
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Download Foodborne Enterobacteriaceae of Animal Origin Epidemic Characteristics of Drug Resistance Pathogenic Mechanisms and Novel Control Measures book written by Fangkun Wang,Dongyan Niu,Zhang Wan Jiang, available in PDF, EPUB, and Kindle, or read full book online anywhere and anytime. Compatible with any devices.

Practical Guide to Chemical Safety Testing

Practical Guide to Chemical Safety Testing Book
Author : Derek J. Knight,Mike B. Thomas
Publisher : iSmithers Rapra Publishing
Release : 2003
ISBN : 9781859573723
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Annotation This book describes the different tests that must be performed on new chemicals and other materials to demonstrate to the regulatory authorities that they are safe for use. Tests vary from physico-chemical, measuring properties such as melting point and density, through genetic toxicity studies, to mammalian toxicology and studies to investigate effects on the environment. This book describes clearly the process of obtaining approval for use in a variety of global regions and across different applications. It also explains why different tests are performed and the implications of the results.

Neuroglia

Neuroglia Book
Author : Sergey Kasparov
Publisher : MDPI
Release : 2019-06-17
ISBN : 3038979902
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Neuroglia is now published as part of Brain Sciences with a new section Editor-in-Chief Prof. Sergey Kasparov.

Handbook of In Vivo Chemistry in Mice

Handbook of In Vivo Chemistry in Mice Book
Author : Katsunori Tanaka,Kenward Vong
Publisher : John Wiley & Sons
Release : 2020-02-25
ISBN : 3527344322
Language : En, Es, Fr & De

DOWNLOAD

Book Description :

Provides timely, comprehensive coverage of in vivo chemical reactions within live animals This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers decide which tools are suitable and best for their experimental needs. The Handbook of In Vivo Chemistry in Mice: From Lab to Living System introduces readers to general information about live animal experiments and detection methods commonly used for these animal models. It focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release. Topics include: currently available mouse models; biocompatible fluorophores; radionuclides for radiodiagnosis/radiotherapy; live animal imaging techniques such as positron emission tomography (PET) imaging; magnetic resonance imaging (MRI); ultrasound imaging; hybrid imaging; biocompatible chemical reactions; ligand-directed nucleophilic substitution chemistry; biorthogonal prodrug release strategies; and various selective targeting strategies for live animals. -Completely covers current techniques of in vivo chemistry performed in live animals -Describes general information about commonly used live animal experiments and detection methods -Focuses on chemistry-based techniques to develop selective in vivo targeting methodologies, as well as strategies for in vivo chemistry and drug release -Places emphasis on material properties required for the development of appropriate compounds to be used for imaging and therapeutic purposes in preclinical applications Handbook of In Vivo Chemistry in Mice: From Lab to Living System will be of great interest to pharmaceutical chemists, life scientists, and organic chemists. It will also appeal to those working in the pharmaceutical and biotechnology industries.