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A History Of Modern Immunology

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A History of Modern Immunology

A History of Modern Immunology Book
Author : Zoltan A. Nagy
Publisher : Academic Press
Release : 2013-10-11
ISBN : 0124201083
Language : En, Es, Fr & De

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Book Description :

A History of Modern Immunology: A Path Toward Understanding describes, analyzes, and conceptualizes several seminal events and discoveries in immunology in the last third of the 20th century, the era when most questions about the biology of the immune system were raised and also found their answers. Written by an eyewitness to this history, the book gives insight into personal aspects of the important figures in the discipline, and its data driven emphasis on understanding will benefit both young and experienced scientists. This book provides a concise introduction to topics including immunological specificity, antibody diversity, monoclonal antibodies, major histocompatibility complex, antigen presentation, T cell biology, immunological tolerance, and autoimmune disease. This broad background of the discipline of immunology is a valuable companion for students of immunology, research and clinical immunologists, and research managers in the pharmaceutical and biotechnology industries. Contains the history of major breakthroughs in immunology featured with authenticity and insider details Gives an insight into personal aspects of the players in the history of immunology Enables the reader to recognize and select data of heuristic value which elucidate important facets of the immune system Provides good examples and guidelines for the recognition and selection of what is important for the exploration of the immune system Gives clear separation of descriptive and interpretive parts, allowing the reader to distinguish between facts and analysis provided by the author

A History of Immunology

A History of Immunology Book
Author : Arthur M. Silverstein
Publisher : Elsevier
Release : 2012-12-02
ISBN : 0080925839
Language : En, Es, Fr & De

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Book Description :

This is a professional-level intellectual history of the development of immunology from about 1720 to about 1970. Beginning with the work and insights of the early immunologists in the 18th century, Silverstein traces the development of the major ideas which have formed immunology down to the maturation of the discipline in the decade following the Second World War. Emphasis is placed on the philosophic and sociologic climate of the scientific milieu in which immunology has developed, providing a background to the broad culture of the discipline. A professional-level intellectual history of the development of immunology from about 1720 to 1970, with emphasis placed on the social climate of the scientific milieu in which modern immunology evolved Written by an author very well known both as a historian of medical science and for his substantial research contributions to the immunopathology of the eye The only complete history of immunology available

Immunology in the Twentieth Century

Immunology in the Twentieth Century Book
Author : Domenico Ribatti
Publisher : Academic Press
Release : 2018-04-24
ISBN : 0128161469
Language : En, Es, Fr & De

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Book Description :

Immunology in the Twentieth Century: From Basic Science to Clinical Application grew out of common knowledge that those who survived many of the common infectious diseases rarely contracted the same disease again. This book charts the historical development of this vital branch of medicine in a concise volume, covering both the basic science involved and the clinical applications. Immunology as a distinctive subject developed in the mid-twentieth century as researchers started to understand how the adaptive immune system aids the defense against pathogens. The subject has grown in importance and diversified into specialist fields, such as immunohistochemistry, immunogenetics and immunopathology. Provides a concise overhead of the history of immunology and its applications in medicine Includes a discussion of the scientists who were pioneers in landmark discoveries in immunology Summarizes the clinical applications of major discoveries

A History of Medical Bacteriology and Immunology

A History of Medical Bacteriology and Immunology Book
Author : W. D. Foster
Publisher : Butterworth-Heinemann
Release : 2014-05-20
ISBN : 1483162451
Language : En, Es, Fr & De

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Book Description :

A History of Medical Bacteriology and Immunology provides the account of the history of bacteriology from the year 1900 to 1938. This book presents details about the discovery of the important pathogenic bacteria of man, of how they were shown to be causally related to disease, and of the use of these discoveries in the diagnosis, treatment, and prevention of disease. Other topics discussed include the development of the germ theory of infectious diseases; contribution of Louis Pasteur and Robert Koch to medical bacteriology; and discovery of the more important human pathogenic bacteria. This text also discusses the scientific basis and practical application of immunology to medicine; main developments in bacteriology during the early 20th century; and chemotherapy of bacterial disease. This medically oriented text is beneficial for students and individuals conducting study on medical bacteriology and immunology.

A History of Transplantation Immunology

A History of Transplantation Immunology Book
Author : Leslie Brent
Publisher : Academic Press
Release : 1996-11-18
ISBN : 9780080533995
Language : En, Es, Fr & De

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Book Description :

Those entering the field of transplantation are frequently unaware of the topics historical roots and even of the background on which modern discoveries in tolerance, histocompabatibility antigens, and xenotransplantation are based. A History of Transplantation Immunology is an account, written by one of the founding fathers of the field, of how tissue and organ transplantation has become one of the most successful branches of late 20th century medicine. The book helps place the work of contemporary scientists into its proper context and makes fascinating reading for immunologists in all stages of their career. Describes landmarks in immunology and places them in historical context Beautifully written by one of the founding fathers of the field Portrays the surprising history of events in a colorful and readable manner Contains biographical sketches of some of the pioneers Illustrates the development of key ideas in immunology--tolerance, graft rejection, and transplantation Foreword by Ray Owen

Metchnikoff and the Origins of Immunology

Metchnikoff and the Origins of Immunology Book
Author : Alfred I. Tauber,Leon Chernyak
Publisher : Oxford University Press on Demand
Release : 1991
ISBN : 019506447X
Language : En, Es, Fr & De

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Book Description :

This fascinating intellectual history is the first critical study of the work of Elie Metchnikoff, the founding father of modern immunology. Metchnikoff authored and championed the theory that phagocytic cells actively defend the host body against pathogens and diseased cells. His program developed from comparative embryological studies that sought to establish genealogical relations between species at the dawn of the Darwinian revolution. In this scientific biography, Tauber and Chernyak explore ore Metchnikoff's development as an embryologist, showing how it prepared him to propose his theory of host-pathogen interaction. They discuss the profound impact of Darwin's theory of evolution on Metchnikoff's progress, and the influence of 19th century debates on vitalism, teleology, and mechanism. As a case study of scientific discovery, this work offers lucid insight into the process of creative science and its dependence on cultural and philosophic sources. Immunologists and historians of science and medicine will find it an absorbing and accessible account of a remarkable individual.

Crafting Immunity

Crafting Immunity Book
Author : Jennifer Keelan
Publisher : Routledge
Release : 2017-03-02
ISBN : 1351947893
Language : En, Es, Fr & De

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Book Description :

Immunity is as old as illness itself, yet historians have only just begun to take up the challenge of reconstructing the modern transformation of attempts to protect against disease. Crafting Immunity assembles in one volume the most recent efforts of an international group of scholars to place the diverse practices of immunity in their historical contexts. It is this diversity that provides the book with its greatest source of strength. Collectively, the papers in this volume suggest that it was the craft-like, small-scale, and local conditions of clinical medicine that turned the immunity of individuals and populations into biomedical objects. That is to say, the modern conception of immunity was at least as much the product of the work of healing as it was the systematic result of discoveries about the immune system. Working outside the narrow confines of laboratory histories, Crafting Immunity is the first attempt to set the problems of immunity into a variety of social, technological, institutional and intellectual contexts. It will appeal not only to historians and sociologists of health, but also to social and cultural historians interested in the biomedical creation of modern health regimens.

Between Hope and Fear

Between Hope and Fear Book
Author : Michael Kinch
Publisher : Simon and Schuster
Release : 2018-07-03
ISBN : 1681778203
Language : En, Es, Fr & De

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Book Description :

If you have a child in school, you may have heard stories of long-dormant diseases suddenly reappearing—cases of measles, mumps, rubella, and whooping cough cropping up everywhere from elementary schools to Ivy League universities because a select group of parents refuse to vaccinate their children. Between Hope and Fear tells the remarkable story of vaccine-preventable infectious diseases and their social and political implications. While detailing the history of vaccine invention, Kinch reveals the ominous reality that our victories against vaccine-preventable diseases are not permanent—and could easily be undone. In the tradition of John Barry’s The Great Influenza and Siddhartha Mukherjee’s The Emperor of All Maladies, Between Hope and Fear relates the remarkable intersection of science, technology, and disease that has helped eradicate many of the deadliest plagues known to man.

A New History of Vaccines for Infectious Diseases

A New History of Vaccines for Infectious Diseases Book
Author : Anthony Robert Rees
Publisher : Academic Press
Release : 2022-01-04
ISBN : 0128127554
Language : En, Es, Fr & De

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Book Description :

A New History of Vaccines for Infectious Diseases: Immunization - Chance and Necessity covers the developments of vaccines and how they have obliterated many fatal diseases and infections over time. The book treads a neutral path but does not avoid discussion. As uncertainty in the outcome of vaccination can only be determined by experiment, the path to vaccine development has been scientifically complex because the immune system and the manner in which humans respond to infection is variable and complex. Finally, the book describes the risks and benefits of vaccines in a visibly objective manner. Gives an objective description of the science behind vaccine discovery Presents awareness and discussions on controversies, both past and present Provides historical context to the scientific aspects of immunization, including what worked, what didn't, and why Written by a scientist with no ‘vested interest’ in vaccine development Clears up many misunderstandings for today’s vaccination policies

A Body Worth Defending

A Body Worth Defending Book
Author : Ed Cohen
Publisher : Duke University Press
Release : 2009-09-25
ISBN : 0822391112
Language : En, Es, Fr & De

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Book Description :

Biological immunity as we know it does not exist until the late nineteenth century. Nor does the premise that organisms defend themselves at the cellular or molecular levels. For nearly two thousand years “immunity,” a legal concept invented in ancient Rome, serves almost exclusively political and juridical ends. “Self-defense” also originates in a juridico-political context; it emerges in the mid-seventeenth century, during the English Civil War, when Thomas Hobbes defines it as the first “natural right.” In the 1880s and 1890s, biomedicine fuses these two political precepts into one, creating a new vital function, “immunity-as-defense.” In A Body Worth Defending, Ed Cohen reveals the unacknowledged political, economic, and philosophical assumptions about the human body that biomedicine incorporates when it recruits immunity to safeguard the vulnerable living organism. Inspired by Michel Foucault’s writings about biopolitics and biopower, Cohen traces the migration of immunity from politics and law into the domains of medicine and science. Offering a genealogy of the concept, he illuminates a complex of thinking about modern bodies that percolates through European political, legal, philosophical, economic, governmental, scientific, and medical discourses from the mid-seventeenth century through the twentieth. He shows that by the late nineteenth century, “the body” literally incarnates modern notions of personhood. In this lively cultural rumination, Cohen argues that by embracing the idea of immunity-as-defense so exclusively, biomedicine naturalizes the individual as the privileged focus for identifying and treating illness, thereby devaluing or obscuring approaches to healing situated within communities or collectives.

The Oxford Companion to the History of Modern Science

The Oxford Companion to the History of Modern Science Book
Author : John L. Heilbron
Publisher : Oxford University Press
Release : 2003-02-14
ISBN : 9780195112290
Language : En, Es, Fr & De

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Book Description :

Containing 609 encyclopedic articles written by more than 200 prominent scholars, The Oxford Companion to the History of Modern Science presents an unparalleled history of the field invaluable to anyone with an interest in the technology, ideas, discoveries, and learned institutions that have shaped our world over the past five centuries. Focusing on the period from the Renaissance to the early twenty-first century, the articles cover all disciplines (Biology, Alchemy, Behaviorism), historical periods (the Scientific Revolution, World War II, the Cold War), concepts (Hypothesis, Space and Time, Ether), and methodologies and philosophies (Observation and Experiment, Darwinism). Coverage is international, tracing the spread of science from its traditional centers and explaining how the prevailing knowledge of non-Western societies has modified or contributed to the dominant global science as it is currently understood. Revealing the interplay between science and the wider culture, the Companion includes entries on topics such as minority groups, art, religion, and science's practical applications. One hundred biographies of the most iconic historic figures, chosen for their contributions to science and the interest of their lives, are also included. Above all The Oxford Companion to the History of Modern Science is a companion to world history: modern in coverage, generous in breadth, and cosmopolitan in scope. The volume's utility is enhanced by a thematic outline of the entire contents, a thorough system of cross-referencing, and a detailed index that enables the reader to follow a specific line of inquiry along various threads from multiple starting points. Each essay has numerous suggestions for further reading, all of which favor literature that is accessible to the general reader, and a bibliographical essay provides a general overview of the scholarship in the field. Lastly, as a contribution to the visual appeal of the Companion, over 100 black-and-white illustrations and an eight-page color section capture the eye and spark the imagination.

Measuring Immunity

Measuring Immunity Book
Author : Michael T. Lotze,Angus W. Thomson
Publisher : Elsevier
Release : 2011-05-04
ISBN : 9780080479330
Language : En, Es, Fr & De

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Book Description :

Most of the diseases of modern mankind involve either acute or chronic inflammation. Measuring Immunity integrates the current information available on biomarkers and surrogate assays into a single handbook. It highlights the principles behind various applications, gives a brief summary on how they are conducted and provides detailed and critical analyses of murine models of immunity, clinical trials, and tests to predict utility and benefit. Measuring Immunity is indispensable for scientists and clinicians interested in the clinical applications of modern immunobiology. * Defines which assays of immune function are helpful in the assessment of clinical disorders involving inflammation and immunity * Assesses the dynamics of cellular and soluble factors in the peripheral blood using modern techniques * Includes basic science foundations as well as the approaches currently applied

Immunology The Making of a Modern Science

Immunology  The Making of a Modern Science Book
Author : Richard B. Gallagher,Jean Gilder,Gustav J.V. Nossal,Gaetano Salvatore
Publisher : Elsevier
Release : 1995-07-14
ISBN : 0080534538
Language : En, Es, Fr & De

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Book Description :

Immunology has progressed in spectacular fashion in the last four decades. Studies of the response to infectious agents, transplanted organs and tumours (and the potential to manipulate that response), and the study of the immune system as a model system in molecular cell biology have yielded dramatic advances in our understanding of the mechanisms of immunity. The field has attracted a continuous stream of the brightest theoretical and experimental scientists for over forty years. This book conveys the philosophies and approaches of sixteen of the most successful of these scientists in the form of a series of narratives that describe the circumstances that led to a major discovery in immunology. Contributors not only recall an exciting period of research that helped shape modern immunology, but set it in the personal context of place and time. Jacques Miller, for example, describes the discovery of the function of the thymus, Rolf Zinkernagel explains how experiments on viral immunity led to the discovery of MHC restriction and Susumu Tonegawa provides an account of how antibody gene structure was defined. Medically-important discoveries include descriptions of early studies of autoimmunity by Noel Rose and of tumour immunology by George and Eva Klein. Far from being a collection of disinterested, historical accounts, this volume comprises a series of passionately biographical, personal essays that provide an unusually intimate insight into the scientific process. This book will be essential, and fascinating, reading for all those with an interest in immunology, and in the life sciences in general. For students and teachers, this will provide the background necessary for a true understanding of immunology, and to place subsequent discoveries in perspective.

The Politics of Immunity

The Politics of Immunity Book
Author : Mark Neocleous
Publisher : Verso Books
Release : 2022-03-22
ISBN : 1839764864
Language : En, Es, Fr & De

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Book Description :

The violence and destruction hiding behind the obsession with immunity Our contemporary political condition is obsessed with immunity. The immunity of bodies and the body politic; personal immunity and herd immunity; how to immunize the social system against breakdown. The obsession intensifies with every new crisis and the mobilization of yet more powers of war and police, from quarantine to border closures and from vaccination certificates to immunological surveillance. Engaging four key concepts with enormous cultural weight – Cell, Self, System and Sovereignty – Politics of Immunity moves from philosophical biology to intellectual history and from critical theory to psychoanalysis to expose the politics underpinning the way immunity is imagined. At the heart of this imagination is the way security has come to dominate the whole realm of human experience. From biological cell to political subject, and from physiological system to the social body, immunity folds into security, just as security folds into immunity. The book thus opens into a critique of the violence of security and spells out immunity’s tendency towards self-destruction and death: immunity, like security, can turn its aggression inwards, into the autoimmune disorder. Wide-ranging and polemical, Politics of Immunity lays down a major challenge to the ways in which the immunity of the self and the social are imagined.

The Beautiful Cure

The Beautiful Cure Book
Author : Daniel M. Davis
Publisher : University of Chicago Press
Release : 2021-03-19
ISBN : 022637114X
Language : En, Es, Fr & De

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Book Description :

“Visceral.”—Wall Street Journal “Illuminating.”—Publishers Weekly “Heroic.”—Science The immune system holds the key to human health. In The Beautiful Cure, leading immunologist Daniel M. Davis describes how the scientific quest to understand how the immune system works—and how it is affected by stress, sleep, age, and our state of mind—is now unlocking a revolutionary new approach to medicine and well-being. The body’s ability to fight disease and heal itself is one of the great mysteries and marvels of nature. But in recent years, painstaking research has resulted in major advances in our grasp of this breathtakingly beautiful inner world: a vast and intricate network of specialist cells, regulatory proteins, and dedicated genes that are continually protecting our bodies. Far more powerful than any medicine ever invented, the immune system plays a crucial role in our daily lives. We have found ways to harness these natural defenses to create breakthrough drugs and so-called immunotherapies that help us fight cancer, diabetes, arthritis, and many age-related diseases, and we are starting to understand whether activities such as mindfulness might play a role in enhancing our physical resilience. Written by a researcher at the forefront of this adventure, The Beautiful Cure tells a dramatic story of scientific detective work and discovery, of puzzles solved and mysteries that linger, of lives sacrificed and saved. With expertise and eloquence, Davis introduces us to this revelatory new understanding of the human body and what it takes to be healthy.

Essential Immunology for Surgeons

Essential Immunology for Surgeons Book
Author : Oleg Eremin,Herb Sewell
Publisher : Oxford University Press
Release : 2011-04-28
ISBN : 019958687X
Language : En, Es, Fr & De

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Book Description :

Previously published as: The Immunological basis of surgical science and practice, 1992.

On Immunity

On Immunity Book
Author : Eula Biss
Publisher : Graywolf Press
Release : 2014-09-30
ISBN : 1555973272
Language : En, Es, Fr & De

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Book Description :

A New York Times Best Seller A National Book Critics Circle Award Finalist A New York Times Book Review Top 10 Book of the Year A Facebook "Year of Books" Selection One of the Best Books of the Year * National Book Critics Circle Award finalist * The New York Times Book Review (Top 10) * Entertainment Weekly (Top 10) * New York Magazine (Top 10)* Chicago Tribune (Top 10) * Publishers Weekly (Top 10) * Time Out New York (Top 10) * Los Angeles Times * Kirkus * Booklist * NPR's Science Friday * Newsday * Slate * Refinery 29 * And many more... Why do we fear vaccines? A provocative examination by Eula Biss, the author of Notes from No Man's Land, winner of the National Book Critics Circle Award Upon becoming a new mother, Eula Biss addresses a chronic condition of fear-fear of the government, the medical establishment, and what is in your child's air, food, mattress, medicine, and vaccines. She finds that you cannot immunize your child, or yourself, from the world. In this bold, fascinating book, Biss investigates the metaphors and myths surrounding our conception of immunity and its implications for the individual and the social body. As she hears more and more fears about vaccines, Biss researches what they mean for her own child, her immediate community, America, and the world, both historically and in the present moment. She extends a conversation with other mothers to meditations on Voltaire's Candide, Bram Stoker's Dracula, Rachel Carson's Silent Spring, Susan Sontag's AIDS and Its Metaphors, and beyond. On Immunity is a moving account of how we are all interconnected-our bodies and our fates.

Immunity

Immunity Book
Author : Luba Vikhanski
Publisher : Chicago Review Press
Release : 2016-04-01
ISBN : 1613731132
Language : En, Es, Fr & De

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Book Description :

Around Christmas of 1882, while peering through a microscope at starfish larvae in which he had inserted tiny thorns, Russian zoologist Elie Metchnikoff had a brilliant insight: what if the mobile cells he saw gathering around the thorns were nothing but a healing force in action? Metchnikoff's daring theory of immunity—that voracious cells he called phagocytes formed the first line of defense against invading bacteria—would eventually earn the scientist a Nobel Prize, shared with his archrival, as well as the unofficial moniker "Father of Natural Immunity." But first he had to win over skeptics, especially those who called his theory "an oriental fairy tale." Using previously inaccessible archival materials, author Luba Vikhanski chronicles Metchnikoff's remarkable life and discoveries in the first moder n biography of this hero of medicine. Metchnikoff was a towering figure in the scientific community of the early twentieth century, a tireless humanitarian who, while working at the Pasteur Institute in Paris, also strived to curb the spread of cholera, syphilis, and other deadly diseases. In his later years, he startled the world with controversial theories on longevity, launching a global craze for yogurt, and pioneered research into gut microbes and aging. Though Metchnikoff was largely forgotten for nearly a hundred years, Vikhanski documents a remarkable revival of interest in his ideas on immunity and on the gut flora in the science of the twenty-first century.

Viruses and Man A History of Interactions

Viruses and Man  A History of Interactions Book
Author : Milton W. Taylor
Publisher : Springer
Release : 2014-07-21
ISBN : 3319077589
Language : En, Es, Fr & De

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Book Description :

Milton Taylor, Indiana University, offers an easy-to-read and fascinating text describing the impact of viruses on human society. The book starts with an analysis of the profound effect that viral epidemics had on world history resulting in demographic upheavals by destroying total populations. It also provides a brief history of virology and immunology. Furthermore, the use of viruses for the treatment of cancer (viral oncolysis or virotherapy) and bacterial diseases (phage therapy) and as vectors in gene therapy is discussed in detail. Several chapters focus on viral diseases such as smallpox, influenza, polio, hepatitis and their control, as well as on HIV and AIDS and on some emerging viruses with an interesting story attached to their discovery or vaccine development. The book closes with a chapter on biological weapons. It will serve as an invaluable source of information for beginners in the field of virology as well as for experienced virologists, other academics, students, and readers without prior knowledge of virology or molecular biology.