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A Historical Perspective On Evidence Based Immunology

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A Historical Perspective on Evidence Based Immunology

A Historical Perspective on Evidence Based Immunology Book
Author : Edward J. Moticka
Publisher : Newnes
Release : 2015-11-25
ISBN : 0123983754
Language : En, Es, Fr & De

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Book Description :

A Historical Perspective on Evidence-Based Immunology focuses on the results of hypothesis-driven, controlled scientific experiments that have led to the current understanding of immunological principles. The text helps beginning students in biomedical disciplines understand the basis of immunologic knowledge, while also helping more advanced students gain further insights. The book serves as a crucial reference for researchers studying the evolution of ideas and scientific methods, including fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, the generation of diversity and mechanism of tolerance of T cells and B cells, the first cytokines, the concept of autoimmunity, the identification of NK cells as a unique cell type, the structure of antibody molecules and identification of Fab and Fc regions, and dendritic cells. Provides a complete review of the hypothesis-driven, controlled scientific experiments that have led to our current understanding of immunological principles Explains the types of experiments that were performed and how the interpretation of the experiments altered the understanding of immunology Presents concepts such as the division of lymphocytes into functionally different populations in their historical context Includes fundamental insights on immunologic tolerance, interactions of lymphocytes with antigen TCR and BCR, and the generation of diversity and mechanism of tolerance of T and B cells

Systems and Synthetic Immunology

Systems and Synthetic Immunology Book
Author : Shailza Singh
Publisher : Springer Nature
Release : 2020-04-24
ISBN : 9811533504
Language : En, Es, Fr & De

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Book Description :

Systems and Synthetic Immunology focuses on the similarities between biology and engineering at the systems level, which are important for applying engineering theories to biology problems. With the advent of new genomic techniques, there are numerous systematic investigations underway in the scientific world. This volume highlights techniques that can be used to effectively combine two of the most essential biological fields - Systems Biology and Synthetic Immunology. The respective chapters discuss the role of synthetic immunology in biotechnology, production of biomaterials, and their use in vaccine delivery. Further topics include the importance of cytokines; the use of genomic engineering tools in immunotherapy; immunosensors; nanotherapeutics; and bioinformatics tools in biomedical applications. Given its scope, the book offers readers an up-to-date and comprehensive review of this unique and dynamic field of research.

The Theory of Endobiogeny

The Theory of Endobiogeny Book
Author : Kamyar M. Hedayat,Jean-Claude Lapraz
Publisher : Academic Press
Release : 2019-06-18
ISBN : 0128173270
Language : En, Es, Fr & De

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Book Description :

The Theory of Endobiogeny Volume 2: Foundational Concepts for Treatments of Common Clinical Conditions addresses the core elements of the adaptation response to stressors: autonomic nervous system (ANS), corticotropic axis, immunity and digestive tract function. The volume is oriented for clinical practice, offering clear discussions on treating the root cause of numerous common disorders, and symptomatically addressing the destabilizing factor in a vast number of disorders ranging from depression to irritable bowel, and from migraines to insomnia called spasmophilia. Extends the concepts of global systems integrative physiology to practical applications in the clinic Detailed explanations of historical, exam and biological modeling indexes related to the ANS, corticotropic axis, hepatobiliary and exocrine pancreatic function Root cause, mechanisms, symptoms and treatments for disorders of immunity, dysbiosis, infectious diseases and spasmophilia, as well as hepatobiliary and pancreatic insufficiency and congestion Materia medica of 22 key medicinal plants with summary of action and indication of usage according to the theory of Endobigoeny Special monodiets and dietary suggestions for disorder discussed

Bionanotechnology

Bionanotechnology Book
Author : Anil Kumar Anal
Publisher : CRC Press
Release : 2018-02-02
ISBN : 1351643630
Language : En, Es, Fr & De

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Book Description :

This book deals with a subject of high interest and importance in all sectors, including biomedical, food, agriculture, energy, and environment. Biological systems are essential in nanotechnology, and many new applications are being developed by mimicking the natural systems. Approaching these topics from an engineering perspective, the book offers insight on the details of nanoscale fabrication processes as well as cell biology. The basics of biology and chemistry, with a focus on how to engineer the behavior of molecules at the nanoscale, are also explored and analyzed. The aim of the text is to provide the reader with broader knowledge of biological methods for signal transduction and molecular recognitions systems and how they can be replicated in bio-sensing applications. The reader will learn the basic structures and interactions of biomacromolecules for developing biocompatible and eco-friendly devices.

Homeopathy for Mumps

Homeopathy for Mumps Book
Author : Dsh Ann Sorrell Ba(hons)
Publisher : CreateSpace
Release : 2013-09-10
ISBN : 9781492355304
Language : En, Es, Fr & De

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Book Description :

Homeopathy for Mumps is an easy-to-use practical guide for newcomers to homeopathy to self-prescribing safe, non-toxic homeopathic remedies for the common symptoms of the mumps virus in an otherwise healthy child. It does not discourage essential treatment for conditions for which medical supervision should be sought - parents and guardians are encouraged to make their own well-informed decisions regarding vaccinations. Homeopathy treats the person not the disease and homeopathic remedies have no side-effects and cannot weaken your child's immune system. Homeopathy for Mumps is written in an easy to follow style and recommends ten of the most effective homeopathic remedies for the symptoms of mumps in the 30c potency. Homeopathic remedy descriptions are short and self-explanatory. Readers may find the Self-Help chapter especially useful particularly the guidelines on treating fever. This chapter also explains how to recognize and deal with any complications. Care and safety of the child are paramount and professional medical help, which may include classical homeopaths, is advised should problems arise. A choice of international specialist suppliers of homeopathic remedies is included to help locate remedies in various countries. Another important addition is a simple three-step guide to observing and classifying reactions after giving remedies, with follow-up actions if necessary. These suggestions concur with the principles of classical homeopathy to ensure optimal success in prescribing. Homeopathy for Mumps is interspersed with color photographs and pertinent quotations. For instance, does homeopathy work? Paolo Bellavite et al explains: "We now have the results of studies that have used homeopathic remedies under well-known experimental conditions, as well as conventionally produced experimental evidence indirectly explaining homeopathic phenomena. The current scientific literature contains a substantial body of evidence and examples that may provide new insights improving our understanding of the principle of similarity and the action of small (or highly diluted) doses of medicines, particularly on the immune system and host defenses (39-45). These studies document and may clarify some of the specific aspects of the biochemical regulatory mechanisms possibly underlying the observed paradoxical phenomena. The 'simile' - brought back to its biological meaning of the inverted, or paradoxical, effects of the same or similar compounds - can operate under a number of experimental and reproducible conditions." "Anyone who adopts an unprejudiced position will discover that immunology and the whole of modern biology in general can offer a considerable contribution to the understanding of homeopathy in a framework that is not very different from the conventional context. In other words, although it is true that some of the most reductionist molecular lines of modern science are ultimately incompatible with the systemic nature of homeopathic thought, it is equally true that many others are perfectly compatible." (Paolo Bellavite, Anita Conforti, Valeria Piasere, and Riccardo Ortolani, "Immunology and Homeopathy. 1. Historical Background," Evidence-Based Complementary and Alternative Medicine, vol. 2, no. 4, pp. 441-452, 2005. doi:10.1093/ecam/neh141 - distributed under the Creative Commons Attribution License http: //creativecommons.org/licenses/by/3.0/ ). Homeopathy for Mumps also contains additional informative chapters like Brief History and Explanation of Homeopathy, Some Mumps Cases, Some Useful Contacts, and Suggested Reading.

Growing Explanations

Growing Explanations Book
Author : M. Norton Wise
Publisher : Duke University Press
Release : 2004-11-24
ISBN : 9780822333197
Language : En, Es, Fr & De

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Book Description :

For much of the twentieth century scientists sought to explain objects and processes by reducing them to their components—nuclei into protons and neutrons, proteins into amino acids, and so on—but over the past forty years there has been a marked turn toward explaining phenomena by building them up rather than breaking them down. This collection reflects on the history and significance of this turn toward “growing explanations” from the bottom up. The essays show how this strategy—based on a widespread appreciation for complexity even in apparently simple processes and on the capacity of computers to simulate such complexity—has played out in a broad array of sciences. They describe how scientists are reordering knowledge to emphasize growth, change, and contingency and, in so doing, are revealing even phenomena long considered elementary—like particles and genes—as emergent properties of dynamic processes. Written by leading historians and philosophers of science, these essays examine the range of subjects, people, and goals involved in changing the character of scientific analysis over the last several decades. They highlight the alternatives that fields as diverse as string theory, fuzzy logic, artificial life, and immunology bring to the forms of explanation that have traditionally defined scientific modernity. A number of the essays deal with the mathematical and physical sciences, addressing concerns with hybridity and the materials of the everyday world. Other essays focus on the life sciences, where questions such as “What is life?” and “What is an organism?” are undergoing radical re-evaluation. Together these essays mark the contours of an ongoing revolution in scientific explanation. Contributors. David Aubin, Amy Dahan Dalmedico, Richard Doyle, Claus Emmeche, Peter Galison, Stefan Helmreich, Ann Johnson, Evelyn Fox Keller, Ilana Löwy, Claude Rosental, Alfred Tauber

Handbook of Mucosal Immunology

Handbook of Mucosal Immunology Book
Author : Anonim
Publisher : Academic Press
Release : 2012-12-02
ISBN : 0323138527
Language : En, Es, Fr & De

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Book Description :

Researchers have recently made tremendous progress in the area of mucosal immunology, greatly increasing our understanding of the common mucosal immune system, mucosal infections, and oral immunization. However, thisresearch has not previously been made available in a single work. In its large 81/2"x 11"format, Handbook of Mucosal Immunology covers the entire spectrum of mucosal immunity and is organized in two main sections to present the basic biology of the common mucosal immune system and the immune responses of the mucosae. The first section provides an introduction and historical perspective of the mucosal immune system and includes comprehensive discussion of the development and physiology of mucosal defense. It discusses such topics as the structure and function of themucosal epithelium, characteristics of mucosal-associated lymphoid tissue (MALT), Peyers patches, and concepts of mucosal vaccines. The second section focuses on the secretory immune system with special reference to mucosal diseases in the digestive (GALT), respiratory (BALT), and genitourinary tracts. This information is especially important in light of the current interest in the mechanisms, transmission, and prevention of infectious diseases such as AIDS, hepatitis, and tuberculosis. Virtually all chapters have been authored by the original investigators responsible for key observations on which current concepts are based. This handbook will be an invaluable resource for a diverse group of both researchers and practicing clinicians.Molecular biologists, immunologists, veterinarians, public health workers, physicians in specialties from pediatrics to pulmonology, and graduate students of mucosal immunology will all find this handbook the most complete work on the subject.

A History of Transplantation Immunology

A History of Transplantation Immunology Book
Author : Leslie Brent
Publisher : Academic Press
Release : 1996-11-18
ISBN : 9780080533995
Language : En, Es, Fr & De

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Book Description :

Those entering the field of transplantation are frequently unaware of the topics historical roots and even of the background on which modern discoveries in tolerance, histocompabatibility antigens, and xenotransplantation are based. A History of Transplantation Immunology is an account, written by one of the founding fathers of the field, of how tissue and organ transplantation has become one of the most successful branches of late 20th century medicine. The book helps place the work of contemporary scientists into its proper context and makes fascinating reading for immunologists in all stages of their career. Describes landmarks in immunology and places them in historical context Beautifully written by one of the founding fathers of the field Portrays the surprising history of events in a colorful and readable manner Contains biographical sketches of some of the pioneers Illustrates the development of key ideas in immunology--tolerance, graft rejection, and transplantation Foreword by Ray Owen

Conceptual Modelling in Computational Immunology

Conceptual Modelling in Computational Immunology Book
Author : Martina Husakova
Publisher : Tomas Bruckner
Release : 2015-09-10
ISBN : 9788087924013
Language : En, Es, Fr & De

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Book Description :

The natural immune system is an amazing complex system aiming at the homeostasis maintenance of a living organism. The non-linear, dynamic and complex nature of this system renders the behaviour far from predictable. This fact complicates exploration of immune processes and their understanding with traditional in vivo or in vitro strategies. Techniques of computer science are a promising alternative for the investigation of the natural immune system. Computational immunology investigates an inner life of the natural immune system with the assistance of various approaches of computer science (artificial or computational intelligence), mathematics, physics or statistics. It offers in silico strategies helping with the understanding of phenomena that are difficult to explore through traditional techniques. The monograph introduces the historical context of this research area and the first computer science-based applications. It concentrates mainly on conceptual modelling of various biological processes with the usage of particular conceptual languages and approaches (concept maps, entity-relationship diagrams, ontologies, topic maps, SBML, CellML, SBGN, statecharts and UML) differing in the degree of formality and use. Conceptual models are crucial, because they highlight the most important "players" of immune processes and relations between them. Conceptualisation is inevitable especially if we study really complex system. The primary goal of the monograph is to investigate the usefulness of the Agent Modelling Language for conceptualisation of particular immune processes. The Agent Modelling Language (AML) extends the UML for conceptualisation of multi-agent systems. The natural immune system is perceived as the multi-agent system in the monograph. Selected types of AML-based diagrams represent properties and processes occurring in a secondary lymphoid organ - a lymph node where interactions between T-cells and dendritic cells are mainly taken into account.

Encyclopedia of Microbiology

Encyclopedia of Microbiology Book
Author : Thomas M. Schmidt
Publisher : Academic Press
Release : 2019-09-11
ISBN : 0128117370
Language : En, Es, Fr & De

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Book Description :

Encyclopedia of Microbiology, Fourth Edition gathers both basic and applied dimensions in this dynamic field that includes virtually all environments on Earth. This range attracts a growing number of cross-disciplinary studies, which the encyclopedia makes available to readers from diverse educational backgrounds. The new edition builds on the solid foundation established in earlier versions, adding new material that reflects recent advances in the field. New focus areas include `Animal and Plant Microbiomes’ and ‘Global Impact of Microbes`. The thematic organization of the work allows users to focus on specific areas, e.g., for didactical purposes, while also browsing for topics in different areas. Offers an up-to-date and authoritative resource that covers the entire field of microbiology, from basic principles, to applied technologies Provides an organic overview that is useful to academic teachers and scientists from different backgrounds Includes chapters that are enriched with figures and graphs, and that can be easily consulted in isolation to find fundamental definitions and concepts

K hler s Invention

K  hler s Invention Book
Author : Klaus Eichmann
Publisher : Springer Science & Business Media
Release : 2006-01-16
ISBN : 9783764374136
Language : En, Es, Fr & De

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Book Description :

Georges Köhler was one of the most prominent German scientists of recent history. In 1984, at an age of 38, he received the Nobel Prize in Physiology or Medicine, together with N.K. Jerne and C. Milstein, for inventing the technique for generating monoclonal antibodies. This method and its subsequent applications had an enormous impact on basic research, medicine and the biotech industry. In the same year, Köhler became one of the directors of the Max-Planck-Institute of Immunobiology in Freiburg; his unfortunate premature death in 1995 set an end to his extraordinary career. Prof. Klaus Eichmann, who had invited Köhler to become his codirector, is one of the people who were closest to him. This scientific biography commemorates the 10th anniversary of Köhler's untimely death. Köhler's scientific achievements are explained in a way to make them understandable for the general public and discussed in the historical context of immunological research.

Biologics for the Treatment of Allergic Diseases An Issue of Immunology and Allergy Clinics of North America E Book

Biologics for the Treatment of Allergic Diseases  An Issue of Immunology and Allergy Clinics of North America  E Book Book
Author : Lanny J. Rosenwasser
Publisher : Elsevier Health Sciences
Release : 2020-10-15
ISBN : 0323777317
Language : En, Es, Fr & De

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Book Description :

This issue of Immunology and Allergy Clinics, guest edited by Dr. Lanny Rosenwasser, will provide up-to-date clinical concepts regarding Biologics for the Treatments of Allergic Conditions. Articles in this outstanding issue include: Allergic Rhinitis/CRS/Polyposis, Eosinophilic Asthma, Pediatric Asthma, Severe Asthma, ACOS/COPD, Food Allergy, Atopic Dermatitis, Chronic Urticaria, Anaphylaxis, Drug Allergy, Cell Disorders, Biologics and Immunotherapy, and much more.

Cannabis

Cannabis Book
Author : Lucas Richert,Jim Mills
Publisher : MIT Press
Release : 2021-08-03
ISBN : 0262362066
Language : En, Es, Fr & De

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Book Description :

Cannabis consumption, commerce, and control in global history, from the nineteenth century to the present day. This book gathers together authors from the new wave of cannabis histories that has emerged in recent decades. It offers case studies from Africa, Asia, the Americas, Europe, and the Middle East. It does so to trace a global history of the plant and its preparations, arguing that Western colonialism shaped and disseminated ideas in the nineteenth century that came to drive the international control regimes of the twentieth. More recently, the emergence of commercial interests in cannabis has been central to the challenges that have undermined that cannabis consensus. Throughout, the determination of people around the world to consume substances made from the plant has defied efforts to stamp them out and often transformed the politics and cultures of using them. These texts also suggest that globalization might have a cannabis history. The migration of consumers, the clandestine networks established to supply them, and international cooperation on control may have driven much of the interconnectedness that is a key feature of the contemporary world.

Stress Challenges and Immunity in Space

Stress Challenges and Immunity in Space Book
Author : Alexander Chouker
Publisher : Springer Science & Business Media
Release : 2011-12-20
ISBN : 3642222722
Language : En, Es, Fr & De

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Book Description :

Stress of either psychological or physical nature can activate and/or paralyse humans’ innate and adaptive immunity. However, adequate immunity is crucial to the maintenance of health on earth and in space. During space flight, human physiology and health are challenged by complex environmental stressors which might be at their most pronounced during lunar or interplanetary missions. While previous publications have addressed the physiological changes that occur during space flight, this book goes further, by adopting an interdisciplinary approach to analyze the complex interaction of living conditions in space, the immune system, and astronauts’ health. It is explained how such analysis of the consequences of stress for the immune system may help in preventing, diagnosing, and counteracting immune-related alterations in health on earth as well as in space

Immunity

Immunity Book
Author : William E. Paul
Publisher : JHU Press
Release : 2015-11-15
ISBN : 1421418029
Language : En, Es, Fr & De

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Book Description :

Paul argues that we must take advantage of cutting-edge technologies and promising new tools in immunological research.

Beyond Medicine

Beyond Medicine Book
Author : Patricia A. Muehsam
Publisher : New World Library
Release : 2021-11-16
ISBN : 1608687007
Language : En, Es, Fr & De

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Book Description :

A pioneer in the synthesis of science, holistic health, and contemporary spirituality, Dr. Patricia Muehsam introduces and explores a path to health and well-being that is extraordinary in its ease and profound in its results. This groundbreaking work explores what health and healing — physical, mental, emotional, and spiritual — really mean and offers a revolutionary new way to think about health. You’ll discover experiences of illness and healing that defy conventional thinking, explore the ancient wisdom and the modern science of consciousness, and learn practical tools for experiencing Absolute Health — which are also tools for navigating being human.

Meaningful Healthcare Experience Design

Meaningful Healthcare Experience Design Book
Author : Scott Goodwin
Publisher : CRC Press
Release : 2020-05-10
ISBN : 1351646621
Language : En, Es, Fr & De

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Book Description :

This book offers a new perspective on improving healthcare that draws inspiration from sources as diverse as American healthcare history, Lean Six Sigma, patient experience, employee engagement, clinical microsystems, physician burnout, and industrial design thinking. This work focuses on the three value streams that form the foundation of all healthcare service processes: healthcare-worker value stream, patient value stream, and organizational process. The interaction of patients and healthcare workers in the context of these three value streams creates the meaningful experience that is essential to healing and to the success of healthcare organizations. Meaningful healthcare experience design guides the work of designing these value streams and improving them to promote experiences that are meaningful and healing for both patients and healthcare workers.

Understanding Fever and Body Temperature

Understanding Fever and Body Temperature Book
Author : Ewa Grodzinsky,Märta Sund Levander
Publisher : Springer Nature
Release : 2019-08-22
ISBN : 3030218864
Language : En, Es, Fr & De

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Book Description :

This book covers several areas, such as immunology, infectious diseases, physiology, general nursing, and medicine as well as measurement accuracy and the history of our understanding of fever. This book employs an interdisciplinary approach to exploring our concept of body temperature and specifically fever. The present volume revolves around thermometry, taking the reader on a journey from the past to the present. Yet while the emphasis is on the clinical importance of obtaining accurate, quantitative measurements of body temperature, the reader is also introduced to the most recent clinical work on the subject. This book represents a truly cross-disciplinary collaboration, using evidence-based practice to integrate physiological and immunological knowledge. The authors’ intention with this volume is to help readers gain better insight into the importance of using knowledge from different disciplines to develop an appreciation of the different aspects of body temperature. In addition, the reader will come to understand the concept of fever in a broader perspective than is traditionally adopted.

Bacteriophage Applications Historical Perspective and Future Potential

Bacteriophage Applications   Historical Perspective and Future Potential Book
Author : Jessica Nicastro,Shirley Wong,Zahra Khazaei,Peggy Lam,Jonathan Blay,Roderick A. Slavcev
Publisher : Springer
Release : 2016-10-04
ISBN : 3319457918
Language : En, Es, Fr & De

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Book Description :

This book explores key applications of phage biotechnology and reviews recent advances in phage display technologies. The applications covered were selected on the basis of their significance and representativeness in the field. The small size and enormous diversity of bacteriophages make them ideal candidates for numerous applications across many industries. Since the discovery of phages and the advent of phage display systems, considerable attention has been focused on the development of novel therapeutic and industrial applications. Recent studies combine the genomic flexibility of phages with phage display systems in order to generate modified phages for targeted delivery.

Clinical Epidemiology Evidence Based Medicine

Clinical Epidemiology   Evidence Based Medicine Book
Author : David L. Katz
Publisher : SAGE Publications
Release : 2001-08-21
ISBN : 1452264317
Language : En, Es, Fr & De

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Book Description :

"The presentation is consistently excellent. One, the writing is lucid and organized in a way that should be very natural for the clinical reader. Two, the text requires no background in mathematics and uses a minimum of symbols. And, three, the methodological concepts and clinical issues are well integrated through a number of carefully prepared and comprehensive examples." Greg Samsa, Associate Director, Duke Center for Clinical Health Policy Research If a patient is older or younger than, sicker or healthier than, taller or shorter than or simply different from the subjects of a study, do the results pertain? Clinical Epidemiology & Evidence-based Medicine is a resource for all health-care workers involved in applying evidence to the care of their patients. Using clinical examples and citing liberally from the peer-reviewed literature, the book shows how statistical principles can improve medical decisions. Plus, as Katz shows how probability, risk and alternatives are fundamental considerations in all clinical decisions, he demonstrates the intuitive basis for using clinical epidemiolgy as a science underlying medical decisions. After reading this text, the practitioner should be better able to access, interpret, and apply evidence to patient care as well as better understand and control the process of medical decision making.