Computational Intelligence Methods for Bioinformatics and Biostatistics

Computational Intelligence Methods for Bioinformatics and Biostatistics PDF Book
  • Author : Francesco Masulli
  • Publisher : Springer
  • Release : 2009-06-23
  • ISBN : 9783642025044
  • Language : En, Es, Fr & De
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Book Description :

This book constitutes the thoroughly refereed post-conference proceedings of the Fifth International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2008, held in Vietri sul Mare, Italy, in October 2008. The 23 revised full papers presented together with 3 invited lectures were carefully reviewed and selected from 69 submissions. The main goal of the CIBB meetings is to provide a forum open to researchers from different disciplines to present and discuss problems concerning computational techniques in bioinformatics, systems biology and medical informatics with a particular focus on neural networks, machine learning, fuzzy logic, and evolutionary computation methods.

Bioinformatics and Computational Biology Solutions Using R and Bioconductor

Bioinformatics and Computational Biology Solutions Using R and Bioconductor PDF Book
  • Author : Robert Gentleman
  • Publisher : Springer Science & Business Media
  • Release : 2006-01-27
  • ISBN : 9780387293622
  • Language : En, Es, Fr & De
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Book Description :

Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.

Breeding Grasses and Protein Crops in the Era of Genomics

Breeding Grasses and Protein Crops in the Era of Genomics PDF Book
  • Author : Gintaras Brazauskas
  • Publisher : Springer
  • Release : 2018-04-25
  • ISBN : 9783319895789
  • Language : En, Es, Fr & De
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Book Description :

This book includes papers presented at the 2017 Joint meeting of Fodder Crops and Amenity Grasses Section and Protein Crops Working Group of EUCARPIA-Oil and Protein Crops Section. The theme of the meeting “Breeding Grasses and Protein Crops in the Era of Genomics” has been divided into six parts: (1) Utilisation of genetic resources and pre-breeding, (2) Genetic improvement of quality and agronomic traits, (3) Breeding for enhanced stress tolerance (4) Implementation of phenomics and biometrics, (5) Development of genomic tools and bioinformatics and (6) Reports of Parallel Sessions.

The Statistical Analysis of Functional MRI Data

The Statistical Analysis of Functional MRI Data PDF Book
  • Author : Nicole Lazar
  • Publisher : Springer Science & Business Media
  • Release : 2008-06-10
  • ISBN : 9780387781914
  • Language : En, Es, Fr & De
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Book Description :

The study of brain function is one of the most fascinating pursuits of m- ern science. Functional neuroimaging is an important component of much of the current research in cognitive, clinical, and social psychology. The exci- ment of studying the brain is recognized in both the popular press and the scienti?c community. In the pages of mainstream publications, including The New York Times and Wired, readers can learn about cutting-edge research into topics such as understanding how customers react to products and - vertisements (“If your brain has a ‘buy button,’ what pushes it?”, The New York Times,October19,2004),howviewersrespondtocampaignads(“Using M. R. I. ’s to see politics on the brain,” The New York Times, April 20, 2004; “This is your brain on Hillary: Political neuroscience hits new low,” Wired, November 12,2007),howmen and womenreactto sexualstimulation (“Brain scans arouse researchers,”Wired, April 19, 2004), distinguishing lies from the truth (“Duped,” The New Yorker, July 2, 2007; “Woman convicted of child abuse hopes fMRI can prove her innocence,” Wired, November 5, 2007), and even what separates “cool” people from “nerds” (“If you secretly like Michael Bolton, we’ll know,” Wired, October 2004). Reports on pathologies such as autism, in which neuroimaging plays a large role, are also common (for - stance, a Time magazine cover story from May 6, 2002, entitled “Inside the world of autism”).

Combined Discrete and Continual Approaches in Biological Modelling

Combined Discrete and Continual Approaches in Biological Modelling PDF Book
  • Author : Alexander E. Filippov
  • Publisher : Springer Nature
  • Release : 2020-06-30
  • ISBN : 9783030415280
  • Language : En, Es, Fr & De
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Book Description :

Basic laws of nature are rather simple, but observed biological structures and their dynamic behaviors are unbelievably complicated. This book is devoted to a study of this “strange” relationship by applying mathematical modeling to various structures and phenomena in biology, such as surface patterns, bioadhesion, locomotion, predator-prey behavior, seed dispersal, etc. and revealing a kind of self-organization in these phenomena. In spite of diversity of biological systems considered, two main questions are (1) what does self-organization in biology mean mathematically and (2) how one can apply this knowledge to generate new knowledge about behavior of particular biological system? We believe that this kind of “biomimetics” in computer will lead to better understanding of biological phenomena and possibly towards development of technical implications based on our modeling.

Modeling Phase Transitions in the Brain

Modeling Phase Transitions in the Brain PDF Book
  • Author : D. Alistair Steyn-Ross
  • Publisher : Springer Science & Business Media
  • Release : 2010-03-14
  • ISBN : 9781441907967
  • Language : En, Es, Fr & De
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Book Description :

Foreword by Walter J. Freeman. The induction of unconsciousness using anesthetic agents demonstrates that the cerebral cortex can operate in two very different behavioral modes: alert and responsive vs. unaware and quiescent. But the states of wakefulness and sleep are not single-neuron properties---they emerge as bulk properties of cooperating populations of neurons, with the switchover between states being similar to the physical change of phase observed when water freezes or ice melts. Some brain-state transitions, such as sleep cycling, anesthetic induction, epileptic seizure, are obvious and detected readily with a few EEG electrodes; others, such as the emergence of gamma rhythms during cognition, or the ultra-slow BOLD rhythms of relaxed free-association, are much more subtle. The unifying theme of this book is the notion that all of these bulk changes in brain behavior can be treated as phase transitions between distinct brain states. Modeling Phase Transitions in the Brain contains chapter contributions from leading researchers who apply state-space methods, network models, and biophysically-motivated continuum approaches to investigate a range of neuroscientifically relevant problems that include analysis of nonstationary EEG time-series; network topologies that limit epileptic spreading; saddle--node bifurcations for anesthesia, sleep-cycling, and the wake--sleep switch; prediction of dynamical and noise-induced spatiotemporal instabilities underlying BOLD, alpha-, and gamma-band Hopf oscillations, gap-junction-moderated Turing structures, and Hopf-Turing interactions leading to cortical waves.

Bioinformatics Research and Applications

Bioinformatics Research and Applications PDF Book
  • Author : Zhipeng Cai
  • Publisher : Springer Nature
  • Release : 2020-08-17
  • ISBN : 9783030578213
  • Language : En, Es, Fr & De
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Book Description :

This book constitutes the proceedings of the 16th International Symposium on Bioinformatics Research and Applications, ISBRA 2020, held in Moscow, Russia, in December 2020. The 23 full papers and 18 short papers presented in this book were carefully reviewed and selected from 131 submissions. They were organized in topical sections named: genome analysis; systems biology; computational proteomics; machine and deep learning; and data analysis and methodology.

Multivariate Statistical Machine Learning Methods for Genomic Prediction

Multivariate Statistical Machine Learning Methods for Genomic Prediction PDF Book
  • Author : Osval Antonio Montesinos López
  • Publisher : Springer Nature
  • Release : 2022-02-14
  • ISBN : 9783030890100
  • Language : En, Es, Fr & De
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Book Description :

This book is open access under a CC BY 4.0 license This open access book brings together the latest genome base prediction models currently being used by statisticians, breeders and data scientists. It provides an accessible way to understand the theory behind each statistical learning tool, the required pre-processing, the basics of model building, how to train statistical learning methods, the basic R scripts needed to implement each statistical learning tool, and the output of each tool. To do so, for each tool the book provides background theory, some elements of the R statistical software for its implementation, the conceptual underpinnings, and at least two illustrative examples with data from real-world genomic selection experiments. Lastly, worked-out examples help readers check their own comprehension.The book will greatly appeal to readers in plant (and animal) breeding, geneticists and statisticians, as it provides in a very accessible way the necessary theory, the appropriate R code, and illustrative examples for a complete understanding of each statistical learning tool. In addition, it weighs the advantages and disadvantages of each tool.

The Calculus of Life

The Calculus of Life PDF Book
  • Author : Andrés Moya
  • Publisher : Springer
  • Release : 2015-04-13
  • ISBN : 9783319169705
  • Language : En, Es, Fr & De
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Book Description :

This book explores the exciting world of theoretical biology and is divided into three sections. The first section examines the roles played by renowned scientists such as Jacob, Monod, Rosen, Turing, von Bertalanffy, Waddington and Woodger in developing the field of theoretical biology. The second section, aided with numerous examples, supports the idea that logic and computing are suitable formal languages to describe and understand biological phenomena. The third and final section is, without doubt, the most intellectually challenging and endeavors to show the possible paths we could take to compute a cell - the basic unit of life - or the conditions required for a predictive theory of biological evolution; ultimately, a theory of life in the light of modern Systems Biology. The work aims to show that modern biology is closer than ever to making Goethe's dream come true and that we have reached a point where synthetic and analytical traditions converge to shed light on the living being as a whole.

Computational Electrostatics for Biological Applications

Computational Electrostatics for Biological Applications PDF Book
  • Author : Walter Rocchia
  • Publisher : Springer
  • Release : 2014-11-29
  • ISBN : 9783319122113
  • Language : En, Es, Fr & De
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Book Description :

This book presents established and new approaches to perform calculations of electrostatic interactions at the nanoscale, with particular focus on molecular biology applications. It is based on the proceedings of the Computational Electrostatics for Biological Applications international meeting, which brought together researchers in computational disciplines to discuss and explore diverse methods to improve electrostatic calculations. Fostering an interdisciplinary approach to the description of complex physical and biological problems, this book encompasses contributions originating in the fields of geometry processing, shape modeling, applied mathematics, and computational biology and chemistry. The main topics covered are theoretical and numerical aspects of the solution of the Poisson-Boltzmann equation, surveys and comparison among geometric approaches to the modelling of molecular surfaces and related discretization and computational issues. It also includes a number of contributions addressing applications in biology, biophysics and nanotechnology. The book is primarily intended as a reference for researchers in the computational molecular biology and chemistry fields. As such, it also aims at becoming a key source of information for a wide range of scientists who need to know how modeling and computing at the molecular level may influence the design and interpretation of their experiments.

Chemical Complexity

Chemical Complexity PDF Book
  • Author : Alexander S. Mikhailov
  • Publisher : Springer
  • Release : 2017-08-10
  • ISBN : 9783319573779
  • Language : En, Es, Fr & De
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Book Description :

This book provides an outline of theoretical concepts and their experimental verification in studies of self-organization phenomena in chemical systems, as they emerged in the mid-20th century and have evolved since. Presenting essays on selected topics, it was prepared by authors who have made profound contributions to the field. Traditionally, physical chemistry has been concerned with interactions between atoms and molecules that produce a variety of equilibrium structures - or the 'dead' order - in a stationary state. But biological cells exhibit a different 'living' kind of order, prompting E. Schrödinger to pose his famous question “What is life?” in 1943. Through an unprecedented theoretical and experimental development, it was later revealed that biological self-organization phenomena are in complete agreement with the laws of physics, once they are applied to a special class of thermodynamically open systems and non-equilibrium states. This knowledge has in turn led to the design and synthesis of simple inorganic systems capable of self-organization effects. These artificial 'living organisms' are able to operate on macroscopic to microscopic scales, even down to single-molecule machines. In the future, such research could provide a basis for a technological breakthrough, comparable in its impact with the invention of lasers and semiconductors. Its results can be used to control natural chemical processes, and to design artificial complex chemical processes with various functionalities. The book offers an extensive discussion of the history of research on complex chemical systems and its future prospects.

Neotropical Ethnoprimatology

Neotropical Ethnoprimatology PDF Book
  • Author : Bernardo Urbani
  • Publisher : Springer Nature
  • Release : 2020-03-23
  • ISBN : 9783030275044
  • Language : En, Es, Fr & De
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Book Description :

Ethnoprimatology is situated at the intersection between the biological and cultural subfields of anthropology. Research on the interface between human and nonhuman primates has been steadily increasing since 1997, when the term ethnoprimatology was first coined. Although there have been studies on human–nonhuman primate interactions in the tropical Americas, no single comprehensive volume has been published that integrates this information to fully understand it in this region. Eighteen novel chapters written by outstanding scholars with various backgrounds are included in this edited volume. They refer to the complex interconnections between different indigenous peoples with New World monkeys that sympatrically share their ancestral territories. Geographically, the range covers all of the Neotropics, from southern Mexico through northern Argentina. This work includes topics such as primates as prey and food, ethnozoology/ethnoecology, cosmology, narratives about monkeys, uses of primates, monkeys as pets, and ethnoclassification. Multiple views as well as diverse theoretical and methodological approaches are found within the pages. In sum, this is a compendium of ethnoprimatological research that will be prized by anthropologists, ethnobiologists, primatologists, conservationists, and zoologists alike. “This book... provides a historical benchmark for all subsequent research in ethnoprimatology in the Neotropics and beyond.” — Leslie E. Sponsel, University of Hawai ́i at Mānoa.