Computational Systems Biology and Bioinformatics

Computational Systems Biology and Bioinformatics PDF Book
  • Author : Jonathan H. Chan
  • Publisher : Springer
  • Release : 2010-11-08
  • ISBN : 9783642167508
  • Language : En, Es, Fr & De
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Book Description :

This book constitutes the refereed proceedings of the First International Conference on Computational Systems-Biology and Bioinformatics, CSBio 2010, held in Bangkok, Thailand, in November 2010. The 19 revised full papers presented were carefully reviewed and selected from a total of 48 submissions. The papers cover a wide range of topics and are organized in five topical sections on modeling and simulation of biological processes, gene expression analysis, biological sequence analysis and network reconstruction, bio-data visualization and biological databases, as well as medical and biomedical informatics.

Advances in Bioinformatics and Computational Biology

Advances in Bioinformatics and Computational Biology PDF Book
  • Author : Marie-France Sagot
  • Publisher : Springer
  • Release : 2007-08-14
  • ISBN : 9783540737315
  • Language : En, Es, Fr & De
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Book Description :

This book constitutes the refereed proceedings of the Second Brazilian Symposium on Bioinformatics, BSB 2007, held in Angra dos Reis, Brazil, in August 2007, co-located with IWGD 2007, the International Workshop on Genomic Databases. The papers address a broad range of current topics in computational biology and bioinformatics.

Bioinformatics and Computational Biology Solutions Using R and Bioconductor

Bioinformatics and Computational Biology Solutions Using R and Bioconductor PDF Book
  • Author : Robert Gentleman
  • Publisher : Springer Science & Business Media
  • Release : 2006-01-27
  • ISBN : 9780387293622
  • Language : En, Es, Fr & De
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Book Description :

Full four-color book. Some of the editors created the Bioconductor project and Robert Gentleman is one of the two originators of R. All methods are illustrated with publicly available data, and a major section of the book is devoted to fully worked case studies. Code underlying all of the computations that are shown is made available on a companion website, and readers can reproduce every number, figure, and table on their own computers.

Breeding Grasses and Protein Crops in the Era of Genomics

Breeding Grasses and Protein Crops in the Era of Genomics PDF Book
  • Author : Gintaras Brazauskas
  • Publisher : Springer
  • Release : 2018-04-25
  • ISBN : 9783319895789
  • Language : En, Es, Fr & De
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Book Description :

This book includes papers presented at the 2017 Joint meeting of Fodder Crops and Amenity Grasses Section and Protein Crops Working Group of EUCARPIA-Oil and Protein Crops Section. The theme of the meeting “Breeding Grasses and Protein Crops in the Era of Genomics” has been divided into six parts: (1) Utilisation of genetic resources and pre-breeding, (2) Genetic improvement of quality and agronomic traits, (3) Breeding for enhanced stress tolerance (4) Implementation of phenomics and biometrics, (5) Development of genomic tools and bioinformatics and (6) Reports of Parallel Sessions.

Probabilistic Modeling in Bioinformatics and Medical Informatics

Probabilistic Modeling in Bioinformatics and Medical Informatics PDF Book
  • Author : Dirk Husmeier
  • Publisher : Springer Science & Business Media
  • Release : 2006-03-30
  • ISBN : 9781846281198
  • Language : En, Es, Fr & De
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Book Description :

Probabilistic Modelling in Bioinformatics and Medical Informatics has been written for researchers and students in statistics, machine learning, and the biological sciences. The first part of this book provides a self-contained introduction to the methodology of Bayesian networks. The following parts demonstrate how these methods are applied in bioinformatics and medical informatics. All three fields - the methodology of probabilistic modeling, bioinformatics, and medical informatics - are evolving very quickly. The text should therefore be seen as an introduction, offering both elementary tutorials as well as more advanced applications and case studies.

The Statistical Analysis of Functional MRI Data

The Statistical Analysis of Functional MRI Data PDF Book
  • Author : Nicole Lazar
  • Publisher : Springer Science & Business Media
  • Release : 2008-06-10
  • ISBN : 9780387781914
  • Language : En, Es, Fr & De
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Book Description :

The study of brain function is one of the most fascinating pursuits of m- ern science. Functional neuroimaging is an important component of much of the current research in cognitive, clinical, and social psychology. The exci- ment of studying the brain is recognized in both the popular press and the scienti?c community. In the pages of mainstream publications, including The New York Times and Wired, readers can learn about cutting-edge research into topics such as understanding how customers react to products and - vertisements (“If your brain has a ‘buy button,’ what pushes it?”, The New York Times,October19,2004),howviewersrespondtocampaignads(“Using M. R. I. ’s to see politics on the brain,” The New York Times, April 20, 2004; “This is your brain on Hillary: Political neuroscience hits new low,” Wired, November 12,2007),howmen and womenreactto sexualstimulation (“Brain scans arouse researchers,”Wired, April 19, 2004), distinguishing lies from the truth (“Duped,” The New Yorker, July 2, 2007; “Woman convicted of child abuse hopes fMRI can prove her innocence,” Wired, November 5, 2007), and even what separates “cool” people from “nerds” (“If you secretly like Michael Bolton, we’ll know,” Wired, October 2004). Reports on pathologies such as autism, in which neuroimaging plays a large role, are also common (for - stance, a Time magazine cover story from May 6, 2002, entitled “Inside the world of autism”).

Foundations on Natural and Artificial Computation

Foundations on Natural and Artificial Computation PDF Book
  • Author : José M. Ferrández
  • Publisher : Springer
  • Release : 2011-05-12
  • ISBN : 9783642213441
  • Language : En, Es, Fr & De
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Book Description :

The two volumes, LNCS 6686 resp. LNCS 6687, constitute the refereed proceedings of the 4th International Work-Conference on the Interplay between Natural and Artificial Computation, IWINAC 2011, held in La Palma, Canary Islands, Spain, in May/June 2011. The 108 revised full papers presented in LNCS 6686 resp. LNCS 6687 were carefully reviewed and selected from numerous submissions. The first part, LNCS 6686, entitled "Foundations on Natural and Artificial Computation", includes all the contributions mainly related to the methodological, conceptual, formal, and experimental developments in the fields of neurophysiology and cognitive science. The second part, LNCS 6687, entitled "New Challenges on Bioinspired Applications", contains the papers related to bioinspired programming strategies and all the contributions related to the computational solutions to engineering problems in different application domains, specially Health applications, including the CYTED ``Artificial and Natural Computation for Health'' (CANS) research network papers.

Combined Discrete and Continual Approaches in Biological Modelling

Combined Discrete and Continual Approaches in Biological Modelling PDF Book
  • Author : Alexander E. Filippov
  • Publisher : Springer Nature
  • Release : 2020-06-30
  • ISBN : 9783030415280
  • Language : En, Es, Fr & De
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Book Description :

Basic laws of nature are rather simple, but observed biological structures and their dynamic behaviors are unbelievably complicated. This book is devoted to a study of this “strange” relationship by applying mathematical modeling to various structures and phenomena in biology, such as surface patterns, bioadhesion, locomotion, predator-prey behavior, seed dispersal, etc. and revealing a kind of self-organization in these phenomena. In spite of diversity of biological systems considered, two main questions are (1) what does self-organization in biology mean mathematically and (2) how one can apply this knowledge to generate new knowledge about behavior of particular biological system? We believe that this kind of “biomimetics” in computer will lead to better understanding of biological phenomena and possibly towards development of technical implications based on our modeling.

Modeling Phase Transitions in the Brain

Modeling Phase Transitions in the Brain PDF Book
  • Author : D. Alistair Steyn-Ross
  • Publisher : Springer Science & Business Media
  • Release : 2010-03-14
  • ISBN : 1441907963
  • Language : En, Es, Fr & De
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Book Description :

Foreword by Walter J. Freeman. The induction of unconsciousness using anesthetic agents demonstrates that the cerebral cortex can operate in two very different behavioral modes: alert and responsive vs. unaware and quiescent. But the states of wakefulness and sleep are not single-neuron properties---they emerge as bulk properties of cooperating populations of neurons, with the switchover between states being similar to the physical change of phase observed when water freezes or ice melts. Some brain-state transitions, such as sleep cycling, anesthetic induction, epileptic seizure, are obvious and detected readily with a few EEG electrodes; others, such as the emergence of gamma rhythms during cognition, or the ultra-slow BOLD rhythms of relaxed free-association, are much more subtle. The unifying theme of this book is the notion that all of these bulk changes in brain behavior can be treated as phase transitions between distinct brain states. Modeling Phase Transitions in the Brain contains chapter contributions from leading researchers who apply state-space methods, network models, and biophysically-motivated continuum approaches to investigate a range of neuroscientifically relevant problems that include analysis of nonstationary EEG time-series; network topologies that limit epileptic spreading; saddle--node bifurcations for anesthesia, sleep-cycling, and the wake--sleep switch; prediction of dynamical and noise-induced spatiotemporal instabilities underlying BOLD, alpha-, and gamma-band Hopf oscillations, gap-junction-moderated Turing structures, and Hopf-Turing interactions leading to cortical waves.

Clinical Applications of Immunomics

Clinical Applications of Immunomics PDF Book
  • Author : Andras Falus
  • Publisher : Springer Science & Business Media
  • Release : 2008-12-23
  • ISBN : 0387792082
  • Language : En, Es, Fr & De
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Book Description :

Innate immunity is one the most evolutionally conserved systems, designed to protect the organism from viruses and bacterial infections, stress and many other types of attacks from the outside world. During the past decade, the capacity of molecular biology and information technology to produce and analyse data have grown exponentially, rapidly reforming many aspects of immunology research in the post-genomics era. As a result, scientific understanding of signalling networks governing the innate immunity response in human tissues and other organisms has evolved beyond recognition, compared to even just a decade ago. Many strategies have been designed over the years to identify novel proteins, which have a crucial role in innate immunity responses by regulating particular signalling pathways. These projects had many advantages, including the definition of novel drug targets, as exemplified by the recent success of anti-TNF therapy, as well as leading to a better, system-wide understanding of the molecular control of innate immunity. In the past few years, a new concept, Immunomics, has been adopted to define an emerging, multidisciplinary field of research (Schonbach, 2003). Although rapid progress has been made to identify the proteins playing pivotal roles in the innate immunity–related signalling pathways (for example, TIR signalling pathways), the catalogue of proteins with a key regulatory function identified and studied is far from completed. Novel proteins need to be char- terised to gain a more comprehensive picture of how signalling networks are regulated.

Selected Topics in Image Science

Selected Topics in Image Science PDF Book
  • Author : O. Nalcioglu
  • Publisher : Springer Science & Business Media
  • Release : 2012-12-06
  • ISBN : 9783642932533
  • Language : En, Es, Fr & De
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Book Description :

The continuing growth of computed tomography (CT) and other imaging techniques motivated us to bring together a comprehensive review of the state of the art in diagnostic imaging. Twelve years after the first appearance of x-ray CT, computerized diagnostic imaging has grown so rapidly in sophistication that it is difficult to follow current developments in this diversified field. In this book, we have attempted to cover the basic developments in several areas. The first part includes some of the fundamental aspects of computerized diagnostic imaging such as algorithms and detectors. Specific applications in emission tomography, digital radiography, ultrasound and nuclear magnetic resonance imaging are dealt with in the secondpart. The contributed papers are by experts currently in the field, whom we feel would certainly enlighten the subject matter and possibly suggest directions for future development. We would like to express our sincere thanks to those who have contributed to this volume. We are sure that their original papers will be beneficial for readers and will also remain as an important reference for researchers in the years to come. We would also like to thank Betty Trent for her expert and patient typing of the entire book. Finally, special thanks are due to Mrs. Ingeborg Mayer of Springer-Verlag for her encouragements, support and patience throughout the preparation of this book.

Field Crops Sustainable Management by PGPR

Field Crops  Sustainable Management by PGPR PDF Book
  • Author : Dinesh Kumar Maheshwari
  • Publisher : Springer Nature
  • Release : 2019-10-12
  • ISBN : 9783030309268
  • Language : En, Es, Fr & De
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Book Description :

This book discusses the most challenging task ahead of researchers from India and around the globe: providing disease-free field crops for the ever-growing world population. In Asia, despite being cultivated in massive volumes, major crops, including cereals, oil seed, tuber and non-tuber vegetables, and fruit, are not meeting the demands of the increasing population. This book showcases naturally occurring beneficial microbes in the form of plant growth promoting rhizobacteria, or PGPR, which make it possible to grow field crops without applying synthetic chemicals. Our understanding of PGPR has increased exponentially in recent decades. They play a multifarious role in developing sustainable systems of crop production and protection. The book focuses on the mechanistic behaviors of PGPRs, their use to develop sustainable cultivation techniques, and their application to enhance crop growth and productivity at the cutting edge of tech-oriented agriculture and to replace hazardous chemicals with microbial inoculants. The book is useful to agronomists, microbiologists, ecologists, plant pathologists, molecular biologists, environmentalists, policy makers, conservationists, and NGOs working on organically grown field crops.